• 수면정신생리
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• 제9권2호
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• pp.86-95
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• 2002

Various sleep-related problems are common in pregnant women. Sleep disorders may result in intrauterine growth restriction as well as harm to pregnant women. Pharmacotherapy of sleep disorders in pregnancy require cautious judgement. All physicians managing sleep-related problems of pregnant women in clinical practice need to understand sleep-related problems and their management in pregnancy. Therefore, I have reviewed the literature on normal sleep, sleep disorders and their management in pregnancy.

• 수면정신생리
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• 제7권2호
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• pp.79-83
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• 2000

Sleep disturbances are frequently associated with neurological disorders. Sleep disorders interfere with rehabilitation of patients with neurological disorders such as stroke and may increase the severity of their symptoms and recurrence rate of stroke. The treatment of sleep apnea syndrome is particularly important in managing patients with cerebral infarction of whom 50-80% have moderate to severe sleep apnea. Sleep apnea produces not only poor quality sleep but also excessive daytime sleepiness, fatigue and lack of energy. Sleep problems frequently found in patients with dementia are sleep-wake cycle abnormality, fragmentation of sleep, nocturnal insomnia, decreased slow wave sleep and REM sleep, and sleep disordered breathing. The management of sleep disturbances is very important for controlling symptoms such as nocturnal wandering and sundowning syndrome in patients with dementia. Parkinson's disease and epilepsy are other neurological disorders that may have sleep disturbances.

• 수면정신생리
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• 제27권1호
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• pp.8-15
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• 2020

Sleep disorder in chronic obstructive pulmonary disease (COPD) is common and typically is associated with oxygen desaturation. The mechanisms of desaturation include hypoventilation and ventilation to perfusion mismatch. Despite the importance of sleep in patients with COPD, this topic is under-assessed in clinical practice. Impaired sleep quality is associated with more severe COPD and may contribute to worse clinical outcomes. Recent data have indicated that specific respiratory management of patients with COPD and sleep disordered breathing improves clinical outcomes. Clinicians managing patients with COPD should pay attention to and actively manage symptoms of comorbid sleep disorders. Management of sleep-related problems in COPD should particularly focus on minimizing sleep disturbance.

• 수면정신생리
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• 제2권1호
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• pp.13-22
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• 1995

To provide the physician with adequate information to diagnose and treat sleepwalking and sleep terrors, the author reviewed clinical features, epidemiology, causative and precipitating factors, polysomnography, diagnosis, differential diagnosis, and treatment for these disorders. Sleepwalking and sleep terrors have been defined as disorders of arousal that occur early in the night and have their onset during stage 3 or 4 sleep. In both disorders, patients are difficult to arouse, and complete amnesia or minimal recall of the episode is frequent. Genetic, developmental, and psychological factors have been identified as causes of both sleepwalking and sleep terrors. Sleepwalking and sleep terrors typically begin in childhood or early adolescence and are usually outgrown by the end of adolescence. When sleepwalking or sleep terrors have a post-pubertal onset or continue to adulthood, psychopathology is a more significant causative factors. The behavior that occur from deep slow-wave sleep can be painful or dangerous to the individual and/or disturbing to those close to that individual. The assessment of patients suspected of having these conditions requires a thorough medical and sleep history. The most important consideration in managing patients with sleepwalking or sleep terrors episodes is protection from injury.

• 수면정신생리
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• 제29권2호
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• pp.40-44
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• 2022

Bipolar disorders are a group of mood disorders characterised by relapsing mood episodes throughout the course of illness. Patients with bipolar disorders commonly present with various sleep problems. Patients in a manic episode generally show decreased need of sleep and those in a depressed episode frequently complain about hypersomnia. Current literature even points to evidence that patients with bipolar disorder in euthymic state may still show signs of sleep disturbances when compared to the general population. Clinicians may also note intricate interactions between changes of circadian rhythm and evolution of mood episodes in patients with bipolar disorder. Also, commonly prescribed medications which plays a crucial role in treatment of bipolar disorders including mood stabilisers and antipsychotic medications often cause significant weight gain over time. Being a risk factor of sleep apnoea, weight gain can predispose the patient to develop sleep apnoea. In this narrative review, we summarised current evidence and literature regarding characteristics of circadian rhythm and comorbid sleep apnoea in patients with bipolar disorder. We also present literature regarding implications of circadian disturbance and comorbid sleep apnoea in managing patients with bipolar disorder.

• 수면정신생리
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• 제8권2호
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• pp.83-89
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• 2001

In all ages and countries, dreaming has always been a topic that has interested people. Throughout history, theories about dreaming have been heavily dependent on concurrent theories in related domains. Many researchers have claimed that dreaming occurs during REM and NREM sleep and have rejected the strict association between REM sleep mechanisms and dreams. Although dreams may occur in both REM and NREM periods, they are likely to be produced by different mechanisms during REM and NREM sleep. All physicians managing dreaming-related problems in clinical practice need to understand the multidimensional aspects of dreaming. Therefore, I have reviewed the literature on mechanisms generating and the meaning of dreaming in the neurobiological and psychophysiological perspectives.

• 수면정신생리
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• 제3권1호
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• pp.47-55
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• 1996

Narcolepsy is characterized by sleep attack with excessive daytime sleepiness(EDS), cataplexy, sleep paralysis, and hypnagogic hallucination. Paradoxically, narcoleptics tend to complain of frequent arousals and shallow sleep during the night time despite their excessive sleepiness. However, nocturnal sleep fragmentation in narcoleptics is relatively ignored in treatment strategies, compared with sleep attack/EDS and cataplexy. In our paper, we attempted to investigate further on the poor nocturnal sleep in narcoleptics and to discuss possible treatment interventions. Out of consecutively seen patients at Seoul National University Sleep Disorders Clinic and Division of Sleep Studies, we recruited 57 patients, clinically assessed as having sleep attack and/or EDS. Nocturnal polysomnography and multiple sleep latency test(MSLT) were done in each of the subjects. We selected 19 subjects finally diagnosed as narcolepsy(mean age $26.0{\pm}18.3$ years, 16 men and 3 women) for this study, depending on the nocturnal polysomnographic and MSLT findings as well as clinical history and symptomatology. Any subject co-morbid with other hypersomnic sleep disorders such as sleep apnea or periodic limb movements during sleep was excluded. Sleep staging was done using Rechtschaffen and Kales criteria. Sleep parameters were calculated using PSDENT program(Stanford Sleep Clinic, version 1.2) and were compared with the age-matched normal values provided in the program. In narcoleptics, compared with the normal controls, total wake time was found to be significantly increased with significantly decreased sleep efficiency(p<.01, p<.05, respectively), despite no difference of sleep period time and total sleep time between the two groups. Stage 2 sleep%(p<.05), slow wave sleep%(p<.05), and REM sleep%(p<.01) were found to be significantly decreased in narcoleptics compared with normal controls, accompanied by the significant increase of stage 1 sleep%(p<.01). Age showed negative correlation with slow wave sleep%(p<.05). The findings in the present study indicate significant fragmentation of nocturnal sleep in narcoleptics. Reduction of REM sleep% and the total number of REM sleep periods suggests the disturbance of nocturnal REM sleep distribution in narcoleptics. No significant correlations between nocturnal polysomnographic and MSLT variables in narcoleptics suggest that nocturnal sleep disturbance in narcoleptics may be dealt with, in itself, in diagnosing and managing narcolepsy. With the objective demonstration of qualitative and quantitative characteristics of nocturnal and daytime sleep in narcoleptics, we suggest that more attention be paid to the nocturnal sleep fragmentation in narcoleptics and that appropriate treatment interventions such as active drug therapy and/or circadian rhythm-oriented sleep hygiene education be applied as needed.

• Journal of Korean Biological Nursing Science
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• 제21권4호
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• pp.266-274
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• 2019

Purpose: The aim of this research was to identify the mediating effect of sleep quality on the relationship between job stress and stress response of shift-working nurses. Methods: The participants in this study were 150 nurses who had more than 6 months of shift-working experience. A survey was conducted from May to June 2017 in a hospital in Gyeonggi-do, South Korea. The data were collected through self-report questionnaires. The collected data were analyzed using SAS 9.4 program. The analysis was based on Baron and Kenny's model to examine the mediating effects of sleep quality on the relationship between job stress and stress response of shift-working nurses. Results: In the first and second steps, job stress was identified as a significant predictor of sleep quality (β= .29, p= .001) and stress response (β = .24, p= .004). In the third step, sleep (B = .55, p< .001) was observed as a significant predictor of stress response, and the direct relationship between job stress and stress response was not significant (β= .07, p= .291). Sleep quality was found to exhibit complete mediating effect on the relationship between job stress and stress response. Conclusion: The results of this study suggest that strategies for managing the stress of shift-working nurses should include effective ways to ensure sleep quality.

• 성인간호학회지
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• 제26권2호
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• pp.214-222
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• 2014

Purpose: This study was to identify factors predicting the occurrence of depression among patients with hepatitis C treated with Peg-interferon. Methods: The subjects were 134 patients treated with Peg-interferon after the diagnosis with hepatitis C at the D University Hospital and 3 hospitals located in Busan, South Korea. The predictors of depression were identified by measuring the general characteristics of the subjects and their disease-related characteristics, social support, sleep disorders, and degree of side effects by interferon. The data were analyzed with a t-test, ANOVA, and logistic regression using the SPSS/WIN 18.0 program. Results: Sixty-six point four percent of the subjects suffered from mild to more severe depression. Fatigue, hair loss, itching, and sleep disorders turned out to be significant predictors. In addition, the explanatory power of these variables for the occurrence of depression was 70%. Conclusion: Sleep disorders and drug side effects were determined to have significant influence on the development of depression in hepatitis C patients treated with Peg-interferon. Therefore, the development of nursing intervention programs aimed to prevent depression by effectively managing sleep disorders and side effects is mandated in future to help the given population.

• 한국융합학회논문지
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• 제11권1호
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• pp.33-39
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• 2020

전문의에 의해 옆으로 누워도 편안함을 주는 등 수면과학과 인체공학을 고려한 베개가 개발되었다. 이 베개는 천연라텍스를 소재로 하여 일정시간 지나면 복원력이 떨어지는 점을 개선하였다. 이 베개에 새로운 아이디어가 추가되었는데 베개는 당연이 수면을 위해 사용되는 것이나, 건강관리를 위한 부가적인 기능을 여기에 추가할 수도 있지 않을까 하는 것이었다. 여기서 건강관리는 심각한 질병과 연관된 것으로 알려진 수면무호흡증을 대상으로 한다. 본 논문은 압력센서와 음성센서를 이용해 정보를 구하고 이 정보로부터 질병에 관한 이상증상을 파악하여 전문의에 의뢰하는 종합적인 서비스를 설계함을 목적으로 한다. 그리고 이 시스템의 성공 가능성을 확인하기 위한 기초적인 설계와 구현을 다룬다. 이 설계를 바탕으로 얻어진 정보를 DB화하고 전문의와의 상담을 위한 서버 시스템을 완성하여 수면 무호흡증을 위한 보조건강기기로 역할을 담당할 수 있도록 업그레이드하는 방안에 대해 살펴본다.