• Journal of Dental Rehabilitation and Applied Science
• /
• v.17 no.2
• /
• pp.85-90
• /
• 2001

In order to investigate the amount of oral malodor of denture wearers, concentration of volatile sulfur compounds of 20 denture wearers(10 male, 10 female) was measured by Halimeter(RH-17, Interscan, CA, USA) at following four conditions ; condition 1(with denture) : male - $415.0{\pm}90.1$, female - $430.9{\pm}101.3$ condition 2(immediately after denture removal) : male - $291.4{\pm}35.5$, female - $259.8{\pm}20.4$ condition 3(with denture after 30 minutes immersing in chlorhexidine) :male - $210.1{\pm}25.7$, 여자 - $197.4{\pm}22.2$ condition 4(with denture after 24 hours immersing in chlorhexidine) : male - $120.1{\pm}35.2$, 여자 - $109.2{\pm}20.0$ There was no sexual difference, but, value at the condition 1 showed statistically significant difference from the others(p<0.05). It is dentists' responsibility and privilege to understand and diagnose the strong association between mouth and oral malodor and treat it.

• Journal of Environmental Science International
• /
• v.29 no.3
• /
• pp.241-247
• /
• 2020

Ulmus davidiana Nakai (UDN) has been traditionally used as a herbal medicine in Korea. In the present study, we investigated the anti-ecotoxic potential of a 116 kDa glycoprotein isolated from UDN (UDN glycoprot ein) in regulating fecal malodor and feed efficiency in mice. We found that UDN glycoprotein (200 μg/ml) has an inhibitory effect on the cell death induced by an ecotoxicological endocrine disrupting chemical, bisphenol A, in colon epithelial HT-29 cells. UDN glycoprotein did not show significant differences regarding the weight of ecotoxicity-related organs (liver, heart, kidneys, and spleen) and the levels of serum glutamate oxaloacetate transaminase, glutamate pyruvate transaminase, and lactate dehydrogenase in mice for 2 weeks, compared to the control. Additionally, UDN glycoprotein reduced the levels of hydrogen sulfide and ammonia as markers of fecal malodor in mice. Interestingly, UDN glycoprotein can improve the mouse feed efficiency. In conclusion, our data indicate that anti-ecotoxicological UDN glycoprotein has the ability to increase the feed efficiency and reduce the fecal malodor by maintaining the viability of colonic epithelial cells in mice.

• Journal of Periodontal and Implant Science
• /
• v.30 no.1
• /
• pp.203-212
• /
• 2000

Putrefactive activity within the oral cavity is the principal cause of halitosis. The most common intraoral sites of oral malodor production are tongue, interdental and subgingival areas. The other foci may include faulty restorations, sites of food impaction and abscesses. Periodontal disease frequently involves pathological oral malodor, which is caused mainly by volatile sulfur compounds(VSC), such as hydrogen sulfide, methyl mercaptan, and dimethyl sulfide. The purpose of this study is to evaluate the association between oral malodor and periodontal status. Volatile sulfur compounds in mouth air were estimated by portable sulfide monitor($Halimeter^{TM}$). The results were as follows : 1. The levels of volatile sulfur compounds were significantly greater in a periodontitis group than in a control group(P<0.01). The amounts of VSC in mouth air from patients with periodontal involvement were four times greater than those of the control group. 2. The significant positive correlation was found between VSC concentrations and the number of pocket depth above 4mm(P<0.01), but correlation between VSC concentrations and plaque score was not statistically significant(P>0.05). 3. In the periodontitis group, VSC concentrations of pre-treatment significantly decreased after scaling and root planing(P<0.01). 4. No statistically significant correlation was found between VSC concentrations and sex / age in the periodontitis group. The above results indicate that periodontal disease may play a role as an important factor of oral malodor and deep periodontal pockets are a source of volatile sulfur compounds.

• Journal of Veterinary Clinics
• /
• v.24 no.2
• /
• pp.192-196
• /
• 2007

Oral malodor in companion animals is noticed by owners at first and it makes owners unpleasant. Therefore oral malodor affects the relationship between pet and owner. Oral malodor is produced by some putrefactive bacteria which putrefy proteins to volatile sulfur compounds (VSC) such as methyl mercaptan, hydrogen sulfide and dimethyl sulfide in the food remnants. And oral malodor is mostly consisted with these VSC. On oral examinations in dogs with oral malodor, it is common that plaque and calculus index were increased than normal dogs'. But organoleptic method is subjective to evaluate halitosis, in this study we measured VSC using organoleptic method and portable sulfide monitor to clarify the relationship between halitosis and periodontal disease in dogs with halitosis. And we found that plaque index and calculus index were significantly related with VSC (P<0.05, P<0.05) in measurement using Halimeter. However there was not significant relationship between gingivitis index and VSC. In conclusion, there was the significant, positive relationship between periodontal disease and halitosis.

• Asian-Australasian Journal of Animal Sciences
• /
• v.16 no.12
• /
• pp.1795-1798
• /
• 2003

Fecal malodor is an acute environmental issue to be solved for the intensive animal agriculture in Japan. Among these substances volatile sulfur such as hydrogen sulfide (HS), methanethiol, and dimethyl sulfide, and dimethyl disulfide are the ones most strictly controlled in the Japanese national regulations. In this experiment, we have screened a range of standard strains of chemoheterotrophic bacteria and of the presently isolated soil bacteria for their capacity to decompose HS. We have demonstrated that Comamonas testosteroni $JCM5832^T$ and our isolate Bacillus sp. had a potential to reduce malodor when applied to the pig feces.

• Proceedings of the SCSK Conference
• /
• 2003.09b
• /
• pp.110-116
• /
• 2003

We have developed a high performance powder, which has a quenching efficacy not only for short-chain fatty acids and amines, but also for vinyl ketones (l-octen-3-one, cis-l,5-octadien-3-one), newly found as other key compounds in axillary malodor. By investigating various powders known to have a quenching efficacy, we finally developed a highly porous silica bead containing magnesium oxide. We found that the superior deodorant effect performed by this powder was the result of multiple effects due to both an excellent physical adsorption capability from its high porosity and a specific adsorption of vinyl ketones by magnesium in the powder. An antiperspirant formulation containing both this powder and a Morus alba extract showed good efficacy as a deodorant.

• Proceedings of the SCSK Conference
• /
• 2003.09b
• /
• pp.139-144
• /
• 2003

Using GC/MS and GC/Olfactmetry analysis, we identified two vinyl ketones such as 1-Octen-3-one (OEO) and cis-1, 5-Octadien-3-one (ODO) as key materials in axillary odor. OEO and ODO showed a strong metallic odor and low odor threshold. These two materials were occurred from the reaction of unsaturated long fatty acids in lipids and the iron ion in our body's metabolism. Then, it was recognized that Morus alba (Japanese name, Kuwa) extract, one of the plant extract, showed a very good effect to control the generation of these vinyl ketones due to its remarkable anti-oxidization effects.

• Journal of Oral Medicine and Pain
• /
• v.23 no.3
• /
• pp.263-270
• /
• 1998

Considering various factors contributing oral malodor, the accurate prediction of prognosis is very important to both clinician and patients. The present study has been performed to invetigate the relationship between treatment effeicacy and pre-treatment volatile sulfur compounds (VSC) level. Ninety patients were divided into three groups, A(<150ppb), B(150< <200ppb), and C(>200ppb) groups, according to pre-treatment VSC level detected by Halimeter, and each group included 30 patients. Routine therapeutic measures for oral were provided to each patient which consisted of oral prophylaxis, tooth brushing and flossing instruction, tongue scraping by proper device, and gargling of 0.25% ZnCl2 Solution. The group with high pre-treatment VSC level (>150ppb) showed significant reduction of VSC level at 1 and 3 weeks after. However, the group with low pre-treatment VSC level (<150ppb) did not show any significant reduction during the experimental periods. Collectively, the results suggested that patients with high pre-treatment VSC level show better prognosis.

• Journal of dental hygiene science
• /
• v.12 no.1
• /
• pp.45-53
• /
• 2012

The purpose of this study is to work out plans to reduce oral malodor by carrying out effective methods. In the research, 17 volunteers were selected from the students at Sahmyook Health University's Dental Hygiene Dept. in order to measure the effects of reduction of oral malodor. The results are as follows. 1. As time passes, both the control group and the experimental group proved the effects of the reduction of oral malodor for 20 minutes after the experiment(p<0.05). 2. The experimental group with tooth-brushing showed a statistically significant difference compared with the control group from a lapse of 5 minutes after the experiment to 20 minutes(p<0.05). 3. The experimental group with tongue cleaner did not prove a statistically significant difference compared with the experimental group with toothbrushing( p>0.05). 4. The experimental group in which participants took a candy showed a statistically significant difference compared with the control group after 5 minutes(p<0.05). 5. The experimental group with chewing a gum proved a statistically significant difference compared with the control group for 10 minutes(p<0.05). Using a washing implement of the tongue, taking a candy, and chewing a gum proved the same effect of reducing foul breath as in the case of operating a tooth-brushing. This experiment proves that taking a candy or extending time of chewing a gum was effective in a short time, and using a tongue cleaner or chewing a gum for 5 minutes was a useful method for reducing oral malodor if not operating a tooth-brushing.

• Journal of the Korea Convergence Society
• /
• v.9 no.4
• /
• pp.99-110
• /
• 2018

The data were collected from 171 physiologic malodor patients diagnosed in KUMC halitosis control clinic between 2008 and 2016. We selected 11 independent variables and 3 dependent variables, then planned to extract some convergent common factors affecting their physiologic malodor. We thought that those extracted convergent common factors could be utilized when preparing the contents of oral malodor preventive program. We used multiple regression analysis and path analysis method, for the analysis of influence of 11 independent factors to three salivary dependent factors(resting salivary flow rate, salivary buffering capacity, salivary precipitation rate). We have presented the physiologic malodor patients' chracteristics by descriptive statistical analysis, and also statistically analysed convergent common factors influencing directly or indirectly to their three dependent factors. We could reason that the sex, the character, the intake habit of breakfast, and the regular food intake habit could affect resting salivary flow rate, salivary buffering capacity and salivary precipitation rate.