• 대한두경부종양학회지
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• 제33권2호
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• pp.59-62
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• 2017

Solitary fibrous tumor (SFT) is an uncommon spindle cell neoplasm that is usually presented as a pleural origin localized tumor. There are few cases, found in thyroid. Twenty six cases found in thyroid have been reported since 1993, and two of these were malignant. We report another malignant case in this study; a 55 years old man visited out-patient clinic due to palpable mass of anterior neck, and pathologically diagnosed as malignant SFT of thyroid after surgical resection. In this study, we focus on the clinical features of this uncommon disease along with other literature reviews.

• Archives of Reconstructive Microsurgery
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• 제10권2호
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• pp.111-117
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• 2001

Introduction : The Functional muscle transfer is used to reconstruct the injuried muscle and paralysis of the shoulder. Especially transfer of the trapezius has been the treatment of choice but it has disadvantages of inadequate function and deformed contour, and instability of humeral head in case of acromion resection. We report an operation for shoulder reconstruction after wide resection of malignant fibrous histiocytoma, using rotational latissimus dorsi flap and review the operation method and clinical outcome. Materials and Methods : A patient, 53 year old, with malignant fibrous histiocytoma in the acromioclavicular joint area had been underwent wide excision, including the deltoid, clavicular head of pectoralis major, part of trapezius, lateral 1/3 of clavicle and acromion including scapular spine. The rotational latissimus dorsi flap with its neurovascular pedicle was dissected and then placed over the resected area and transfer of muscle attached at coracoid process was done to achieve stability of the humeral head. The range of motion of the shoulder and test of muscle power were evaluated for functional outcome. Total follow-up period is 2 years 11 months. Results : At last follow-up, the range of motion of the shoulder is abduction $90^{\circ}$, flexion $90^{\circ}$, internal rotation $40^{\circ}$, external rotation $50^{\circ}$ and the muscle power is 4 grade in all direction and then we obtained good functional results. There are no complications such as instability or subluxation of the humeral head and deformed contour and he is a disease-free survival state. Conclusions : The transfered latissimus dorsi flap provides adequate lever arm and stabilization and covering of the humeral head by sufficient muscle volume and width. This procedure can be useful not only for the paralysed deltoid reconstruction but also for use in reconstructive surgery after wide resection of the shoulder for malignant tumor.

• Radiation Oncology Journal
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• 제13권3호
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• pp.225-231
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• 1995

악성 섬유성 조직구종은 상악골부위에서는 매우 드물게 발생하는 악성 종양으로서, 두경부에 발생되는 예가 전체 악성 섬유성 조직구종의 $7{\%}$ 이며 이들 $7{\%}$ 중 $12{\%}$가 상악골에 발생한다고 한다. 상악골의 악성 섬유성 조직구종은 국소재발이나 원격전이가 $55{\%}$의 환자들에서 발생하며 평균 생존기간은 상악골, 하악골 및 구강연부조직의 악성 섬유성 조직구종에 관한 연구에서 30개월로 보고되었다. 상악골의 악성 섬유성 조직구종은 일차적으로 근치적 수술요법이 주 치료방법이다. 방사선치료에 관한 보고들은 대상환자들이 적어서 지금까지 체계적으로 보고되지 않았고, 증례보고에 의한 종양의 퇴행 또는 조직학적 변화가 발표된 바 있으며 일부 저자들은 수술후 방사선치료가 도움이 되지 않으므로 재발성 또는 수술 불가능한 경우에 시행하기를 권하기도 한다. 재발성 또는 전이성 악성 섬유성 조직구종 환자들에서 항암화학요법으로 $33{\%}$의 관해율을 보였다는 보고가 있다. 저자들은 상악골의 악성 섬유성 조직구종 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• 대한두경부종양학회지
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• 제17권2호
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• pp.230-233
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• 2001

Malignant fibrous histiocytoma (MFH) is a sarcoma that occurs principally in soft tissue and typically involved the skeletal muscle and deep fascia. Although it is one of the most common types of soft tissue sarcoma in late adult life, the involvement of the head and neck area is relatively rare. MFH shows variable histologic appearance, and may be classified into several subtypes(storiform-pleomorphic, myxoid, giant cell, inflammatory, angiomatoid) and the storiform-pleomorphic type is the most common type. The authors have recently experienced a case of MFH in the right maxillary sinus, and report it with a brief review of the related literature.

• 대한두경부종양학회지
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• 제37권2호
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• pp.87-90
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• 2021

Solitary fibrous tumor (SFT) is rare mesenchymal tumor usually arising from pleura. SFT can be found at all anatomic site in our body but incidence of SFT is much lower in head and neck region especially at lower neck area. We found a case of SFT that presented as a lower neck mass in a 41-year old woman. Ultrasonography showed a 3×1cm sized hypoechoic mass in the intermuscular fat plane of left lower neck, and computed tomography showed a well circumscribed, low-density mass with contrast enhancement. Fine needle aspiration showed no malignant cells with abundant red blood cells, but it was not possible to completely rule out malignant tumors or nodules clinically. Surgery was performed to make a definitive diagnosis and histopathology showed tightly packed, round to fusiform cells with staghorn shaped vessels at microscopic examination. The tumor cell were positive for CD34 but negative for CD31 and S-100 protein.

• 한국수의병리학회:학술대회논문집
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• 한국수의병리학회 2003년도 추계학술대회초록집
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• pp.54-54
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• 2003

Malignant fibrous histiocytomas (MFHs) is the most common type of soft tissue sarcoma in the old animal with a aggressiveness, a high local recurrence rate and significant metastatic rate, which associated with a poor prognosis. In most histologic and immunohistological studies, the tumor cells raised from a fibroblastic and/or myofibroblastic phenotype, presumably from undifferentiated mesenchymal cell origin. MFHs are usually firm and invasive, arising in the subcutis; metastasis depends on tumor grade (many are grade 3) [1,2]. The primary tumor cells are pleomorphic, varying in appearance from fusiform to round. Often nucleoli are prominent and irregular [5]. Extracellular amorphous eosinophilic material may be prominent and likely represents reactive collagen production by the tumor [5]. (omitted)

• Journal of Chest Surgery
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• 제22권2호
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• pp.297-304
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• 1989

A 45-year old woman with congestive heart failure due to left atrial tumor was operated on. Three tumor masses arising from posterior wall, atrial septum, anterior portion of mitral valve were resected. Pathological diagnosis was malignant fibrous histiocytoma [MFH]. Above one case and sixteen previous reports are reviewed. Eleven cases out of 17 were females. The tumors all originated primarily in the left atrium and 8 had distant metastases. The metastatic sites are lung [4 cases], brain [2 cases], liver, jejunum, cervix and pleura etc. Careful pathologic study is necessary to differentiate the uniformly fatal MFH of the heart from the more common benign atrial myxoma. The treatment modalities are surgical resection, chemotherapy, and radiation therapy & the prognosis of intracardiac MFH is poor. We underwent partial resection of left atrial MFH and obtained symptom relief and patient still alive 7 months post-operatively in state of NYHA class II.

• Journal of Chest Surgery
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• 제46권4호
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• pp.295-298
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• 2013

Solitary fibrous tumor is a rare spindle cell mesenchymal tumor entity, with either benign or malignant behavior that cannot be accurately predicted by histological findings. An intrapulmonary site of origin is even rarer. We report a case of a 51-year-old woman in whom an abnormal nodule in the lower right lung was detected during staging for sigmoid adenocarcinoma. The nodule was excised and pathological examination revealed an intrapulmonary solitary fibrous tumor.

• Archives of Plastic Surgery
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• 제37권1호
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• pp.79-82
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• 2010

Purpose: Carcinosarcomas are rare neoplasms in which both malignant epithelial and mesenchymal elements are identified. We have found only twenty one cases of primary cutaneous carcinosarcoma in the English language literature. Therefore it has been difficult to diagnosis because its unclear etiology and low frequency. Methods: A 31-year-old young man with a protruding mass on his ankle dorsum was examined. The tumor was $7{\times}6{\times}3\;cm$ sized and arose from a burn scar. The mass was wide excised and applied split thickness skin graft. Characteristic pathologic finding was a mixture of squamous cell carcinoma and malignant fibrous histiocytoma. Results: Three months after the operation, the patient died of multiple metastasis to the liver, lung and finally of sepsis despite adjuvant chemotherapy and adjuvant radiotherapy. Conclusion: If a metastatic cutaneous carcinosarcoma is diagnosed, wide excision is required. There should be more aggressive management to minimize the risk of recurrence. Further research into the etiology and pathophysiology of the disease and a more careful differential diagnosis may allow improvement in treatment.

• Journal of Chest Surgery
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• 제39권10호
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• pp.802-804
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• 2006

악성 섬유 조직구종은 사지나 후복막의 연부조직에 주로 발생하는 종양으로 종격동에 발생하는 경우는 극히 드물다. 환자는 71세 남자 환자로 전종격동에 발생한 원발성 종양에 대해 종양 제거술을 시행하였고 조직학적으로 악성 섬유 조직구종으로 진단되었다.