• 제목/요약/키워드: Main component

검색결과 2,137건 처리시간 0.032초

실리마린의 용출개선 및 흰쥐에서의 생체이용률 평가 (Improved Dissolution Characteristics of Silymarin and Their Bioavailability in Rats)

  • 김정훈;장선우;권종원;김원배;최영욱
    • Journal of Pharmaceutical Investigation
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    • 제33권1호
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    • pp.61-65
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    • 2003
  • Silybin is the main component of Cardus marianus extracts originated from Silybum marianum and has a hepato-protective effect. It is a water-insoluble compound and poorly absorbed from the gastrointestinal tract, resulting in very low oral bioavailability(BA). Polymeric mixed-micelle precursor formulation was made to enhance the dissolution rate of silybin, showing the results of pH-independent release profile with increased dissolution. Oral BA of different preparations in rats was evaluated, revealing that the new formulation showed increased BA more than 2-fold and 4-fold compared to the marketed product and Cardus marianus extracts itself, respectively.

음양곽으로부터 Icariin의 분리 및 함량분석 (Isolation and Quantitative Analysis of Icariin from Epimedii Herba)

  • 이혜원;황성원;고병섭;김호경
    • 생약학회지
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    • 제32권1호통권124호
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    • pp.43-48
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    • 2001
  • Epimedii Herba has been used for tonic, cardiotonic, impotency, amnestic and diuretic. Icariin, a main component was isolated from the Epimedii Herba and identified by the spectroscopic methods. In order to evaluate the quality of Epimedii Herba purchased from various regions of Korea, quantitative determination of icariin in Epimedii Herba using HPLC method has been conducted. Quantitative analysis showed the average amount of icariin in commercial 42 samples was 0.34% on the dry weight basis.

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참당귀근 성분이 간의 약물대사효소에 미치는 효과 (Effect of the Constituents of Angelicae gigantis Radix on Hepatic Drug Metabolizing Enzymes)

  • 한정미;이인란;신국현
    • 생약학회지
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    • 제27권4호
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    • pp.323-327
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    • 1996
  • The ether soluble fraction of the roots of Angelicae gigantis Radix caused a significant prolongation of hexobarbital(HB) induced sleeping time in mice. Through systematic fractionation of the ether fraction monitored by bioassays, two pyranocoumarins, decursinol angelate and decursin were isolated as active principles. Decursin, as a main component, exhibited significant prolongation of HB-induced hypnosis as well as significant inhibition of hepatic microsomal drug metabolizing enzyme(DME) activities at relatively high dose which indicated that it is a weak DME inhibitor.

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SaaS 비즈니스 모델별 서비스 기업 경쟁력 결정 요인분석: 그룹웨어, POS 시스템, CRM 및 ERP를 중심으로 (An Analysis on Enterprise Competitive Advantage Determination Factors to Effect Enterprise Results for Each SaaS Business Model: focusing on Group-Wares, POS-System, CRM and ERP)

  • 김신표;이춘열
    • 디지털융복합연구
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    • 제6권2호
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    • pp.65-76
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    • 2008
  • Recently, software distribution method, along with advent of era of Web 2.0, is rapidly evolving from ASP(Application Service Provider) method into SaaS(Soft as a Service) method due to development in concepts and technologies including SOA(Service Oriented Architecture) Web Service, On Demand and Component. Determining factor in market competitiveness of newly emerging SaaS business model will be analyzed by focusing on Group-Wares, POS(Point of Sale) System, CRM(Customer Relationship Management) and ERP(Enterprise Resource Planning), which are the most representative SaaS business models in Korea. It is anticipated that the outcome of analysis of determining factors for market competitiveness for each of the main SaaS Business Models acquired through questionnaire survey can be utilized as important benchmarking material in setting the direction of cultivating SaaS market by the government as well as new entries into SaaS market.

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Reevaluation of Operational Policies for a Reservoir System

  • Ko, Ick-Hwan;Choi, Ye-Hwan
    • 한국농공학회지
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    • 제39권2호
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    • pp.1-8
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    • 1997
  • Abstract The need for integrated reservoir system operation become more intense as the demands from the system increase. A deterministic, three-dimensional discrete incremental dynamic programming approach is presented to derive reservoirs system operational planning strategies. The developed H3DP model optimizes the monthly operation of the Hwachon and Soyang Projects on the North Han river and Chungju Main Project on the South Han river. By using the H3DP model, Hwachon project was reevaluated as a component of the upstream multipurpose storage reservoirs in the basin based on 1993 hydrology. This case study demonstrates the practical use of the developed model for the basin multi-reservoir system operation in an integrated, multipurpose fashion.

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위상이동 방식 Full-Bridge 컨버터의 손실 분석에 관한 연구 (A Study on the Loss Analysis for the Phase-Shaft Full-Bridge Converter)

  • 배진용;김용;백수현;이은영;최근수
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2003년도 춘계학술대회 논문집 전기기기 및 에너지변환시스템부문
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    • pp.157-162
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    • 2003
  • This paper presents the loss analysis of Phase-Shift Full-Bridge Converter. Full-Bridge DC/DC Converter presented in this paper used a phase shift control in the primary side to achieve ZVS (Zero-Voltage-Switching) for main switch. Phase-Shaft Full-Bridge converter have an effect on the high power system. This paper analyses the loss of each component and the various losses in the circuit assessed. The result of the analysis are verified using 2.5kW, 50kHz prototype.

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송전선로용 디지털 고장점 표정장치에 관한 연구 (A Study on Digital Fault Locator for Transmission Line)

  • 이경민;박철원
    • 전기학회논문지P
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    • 제64권4호
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    • pp.291-296
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    • 2015
  • Transmission line is exposed to a large area, and then faults are likely to occur than the other component of power system. When a fault occurs on a transmission line, fault locator helps fast recovery of power supply on power system. This paper deals with the design of a digital fault locator for improvement accuracy of the fault distance estimation and a fault occurrence position for transmission line. The algorithm of a fault locator uses a DC offset removal filter and DFT filter. The algorithm utilizes a fault data of GPS time synchronized. The computed fault information is transmitted to the other side substation through communication. The digital fault locator includes MPU module, ADPU module, SIU module, and a power module. The MMI firmware and software of the fault locator was implemented.

사건수목분석을 통한 수배전설비의 전기화재위험성 분석 (Risk Analysis of Electrical Fire for Electric Power Installations by Event Tree Analysis)

  • 박영호;김두현;김성철
    • 한국안전학회지
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    • 제31권5호
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    • pp.16-21
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    • 2016
  • The purpose of this paper is to conduct ETA on 15 components of power installations: the DS/LBS, LA, MOF, CT, PT, A/V meter, VCB, OCR, COS, PF, Transformer, Condenser(C), Grounding, Cable and Connector. To achieve that, power installations work flow and its components are categorized. Based on performance, human, environmental, management, and safety, this paper drew Initiation events (IE) and End states (ES). ETA is applied to the main functions of each component, and the end states that may occur in one initiation event are suggested. In addition, detailed classification was performed to induce various end states on the basis of the suggested initiation events. If the suggested IEs and ESs are applied on the basis of power installations event cases, it is expected to prevent the same kinds of accident and operate power installations safely.

회전자 구조에 따른 브러시리스 모터 편심 특성 분석 (Analysis of the Eccentric Characteristics of the Brushless Motor by the Rotor Structure)

  • 손병욱;이주
    • 조명전기설비학회논문지
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    • 제24권12호
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    • pp.156-163
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    • 2010
  • The brushless motor is getting widely applied to the automotive component with the advantage of the high efficiency, high reliability and etc.. Most of the motor applications require the low vibration and acoustic noise. The cogging torque is the one of the main cause of the noise and vibration. The step-skewed rotor is used to reduce the cogging torque. We analyze the characteristics of the step-skewed rotor and non skewed rotor with the same stator by using 2-dimensional FEM. And then we analyze the characteristics variation according to the rotor eccentricity. The prototype is made and tested. As the results, the step-skewed rotor structure reduce the cogging torque and local radial force but it is more sensitive to rotor eccentricity.

하이브리드 자동차 고전압 배터리 충, 방전을 위한 49kW급 고효율 양방향 DC/DC 컨버터 설계 (Design of a 49kW high efficiency bidirectional DC-DC converter for charge and discharge of high voltage battery in HEV)

  • 양진영;윤창우;박성식;최세완;박래관;장서건
    • 전력전자학회:학술대회논문집
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    • 전력전자학회 2007년도 추계학술대회 논문집
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    • pp.21-23
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    • 2007
  • In this paper a high efficiency bi-directional DC-DC converter for hybrid vehicles is proposed. The proposed converter a three-phase half-bridge interleaved ZVS converter, is designed to have high efficiency in the main operation range. The component ratings are calculated, the actual devices are selected, and the efficiency analysis has been performed to determine optimal ZVS range. The input and output current ripples are significantly reduced due to the interleaved operation. The dual loop control for the interleaved three-phase converter is also presented. To confirm the proposed convert ter, The simulation and experimental results are presented.

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