• Investigative Magnetic Resonance Imaging
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• v.17 no.3
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• pp.232-238
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• 2013

Purpose : We investigated the possible added value of magnetic resonance imaging (MR) in staging of malignant pleural mesothelioma (MPM) compared to computed tomography (CT). Materials and Methods: We retrospectively enrolled 20 patients (M;F = 14:6; mean age, 53.5 yrs) who diagnosed as MPM by histology and underwent CT and MR at initial evaluation from Jan 1997 to Dec 2012. Two radiologists performed clinical staging by using CT alone or MR alone in consensus. In patients underwent surgery (n = 13), we evaluated the diagnostic accuracy of CT and MR in terms of staging compared to surgical staging. In all patients, we compared clinical staging of CT only and CT with MR. Results: The diagnostic accuracy for T staging of CT only was 23.1% (3/13) and that of combined CT and MR was 38.5% (5/13), respectively. Among 13 patients underwent surgery, surgical stage was higher than combined CT and MR stage in 5 patients, but lower in 3 patients. CT only and combined CT and MR agreed in 85.0% (17/ 20). In cases of disagree (15.0%, 3/20), combined CT and MR showed higher stage than CT only. Conclusion: Combined CT and MR increases the diagnostic accuracy in staging of MPM compared to CT only and is important in determining the appropriate treatment in patients being considered for surgery.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.11
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• pp.555-558
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• 1997

A new approach to silent MR imaging using a rotating DC gradient has been explored and experimentally studied. As is known, acoustic or sound noise has been one of the major problems in handling patients, mainly due to the fast gradient pulsings in interaction with the main magnetic field. The sound noise is also proportionally louder as the magnetic field strength becomes larger. In this article, we have described a new imaging technique using a mechanically rotating DC gradient coil as an approach toward silent MR imaging, i.e., a mechanically rotated DC gradient effectively replaces both the phase encoding as well as the readout gradient pulsings and data obtained in this manner provides a set of project ion data which later can be used or the projection reconstructionorwithsomeinterpolation techniques one can also perform conventional 2-D FFT (Fast Fourier Transform) image reconstruction. We found, with this new technique, that the sound noise intensity compared with the conventional imaging technique, such as spin echo sequence, is reduced down to -20.7 dB or about 117.5 times. The experimental pulse sequence and its principle are described and images obtained by the new silent MR imaging technique are reported.

• Journal of Biomedical Engineering Research
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• v.19 no.3
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• pp.243-250
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• 1998

Reconstruction aspects of spiral scan imaging for ultra fast magnetic resonance imagine(MRI) have been investigated with polar and rectangular coordinates-based reconstruction. For the reconstruction of the spiral scan imaging, acquired data in spiral trjectory should be converted to polar or rectangular grids, where interpolation techniques are used. Various reconstruction algorithms for spiral scan imaging are tested, and reconstructed image qualities are compared with computed phantom. An improved reconstruction algorithm with dc-offset correction in projection domain is proposed, which provides the best reconstructed image quality from the simulation. Image artifact with existing algorithms is completely removed with the proposed method.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.3
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• pp.924-929
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• 2004

Pigmented villonodular synovitis is a rare proliferating process of the synovium, tendon sheaths and bursae usually affecting the bone and joints. The disease can be localized or diffuse. Patients with this condition typically present with symptoms of mild discomfort and associated swelling of the involved joint. However, the spectrum of presentations is broad. Diagnosis of Pigmented villonodular synovitis can be clinically difficult, and plain radiographs are usually nonspecific. Magnetic resonance imaging is a highly diagnostic modality in characterizing pigmented villonodular synovitis when it contains hemosiderin deposits exhibiting low signal intensity on all pulse sequences. Magnetic resonance imaging is recommended for accurate preoperative staging of the disease and for follow up after treatment. I report a case of pigmented nodular synovitis in the knee joint, with review of literatures.

• Journal of the Korean Magnetics Society
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• v.6 no.4
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• pp.272-276
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• 1996

1948년 Harvard 대학의 Purcell교수와 Stanford 대학의 Bloch교수가 핵자기 공명(Nuclear Magnetic Resonance : NMR) 현상을 발견한 이래로 NMR은 물질의 분자단위에서 화학적, 물리학적 성질을 밝혀내는 탁월한 방법으로 널리 이용되어 왔다. NMR 현상을 이용한 영상촬영법(Magnetic Resonance Imaging, MRI)은 1970년대초 Lauterber와 Damadian 교수가 처음 영상을 얻을 수 있다는 가능성을 제시한 이후 급속한 발전을 하여 1980년대 초에는 Moore와 Holland에 의해 의학분야에 응용 가능할 정도의 영상이 얻어졌다. 1980년대 중반부터 상용화 되었으며 최근 그 기법도 NMR현상과 연관된 파라미터인 $T_{1}$, $T_{2}$는 물론 혈류의 속도, 자화율, 확산(Diffusion), Perfusion의 영상기법을 비롯해 혈관조영술(MR Angiography), 뇌기능영상(Functional Imaging)등 과거에는 상상도 할 수 없었던 다양한 영상기법 개발되었다. 여기서는 먼저 MRI의 원리를 설명한 후 MRI의 여러 촬영기법들과 그 응용에 관해 설명하겠다.

• Journal of Yeungnam Medical Science
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• v.26 no.1
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• pp.70-73
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• 2009

A 78-year-old woman presented with weakness of the extremities, dysarthria, dizziness, and sensory impairment. Magnetic resonance imaging showed acute bilateral medial medullary infarction. Contrast enhanced magnetic resonance angiography demonstrated stenosis or occlusion of both intracranial vertebral arteries. We present a rare case of bilateral medullary infarction seen on diffusion-weighted imaging.

• Investigative Magnetic Resonance Imaging
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• v.3 no.1
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• pp.13-19
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• 1999

MRI imaging provides many benefits such as noninvasive, 3-dimensional imaging capabilities. But it has relatively serious drawback that is the long data collection time, compared with other imaging modality. Many studies have been performed for fast MR imaging. But EPI and SEPI (4-6) are required to expensive hardware. In this paper, we introduce to Burst imaging technique. It can reduce imaging time by use of a mulitple RF excitation technique. Further it is easily implemented to the normal MRI system. But a pixel profile in the conventional burst sequence is so poor that excited area by burst sequence is a small portion of a pixel. This causes poor signal to noise ratio in burst image. therefore frequency sweeping of RF pulse for burst imaging sequence is proposed to improve pixel profile. A burst pulse train is shaped by liner or nonlinear frequency sweeping function so that all the spins within a pixel are excited, thereby improving the signal to noise ratio. It also shows that the pixel profiles are dependent on how frequency sweep is made. Computer simulations with Bloch equation and experimental results obtained using a 1.0 T NMR imaging system are presented.

• Biomedical Science Letters
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• v.10 no.2
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• pp.115-120
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• 2004

To investigate the correlation between the magnetic resonance imaging (MRI) of cerebral fat embolism that is induced by injecting oleic acid into 10 cats, and a pathologic diagnosis. Using a microcatheter, 30 ${mu}ell$ of oleic acid was injected into the internal carotid artery of 10 cats. MR T2-weighted image (T2WI), diffusion-weighted image (DWI) and Gadolinium-enhanced T1-weighted image (Gd-enhanced T1WI) were obtained after 30 minutes and 2 hours of embolization. After 30 minutes of the embolization, lesions of very high signal intensity were detected by T2WI in 6 cats, and of slightly high signal intensity in 2 cats; in the remaining 2 cats, signal intensity was normal. DWI showed lesions of very high intensity in 9 cats and of slightly high intensity in one cat. According to the findings of light microscopic examination, infarcted lesions mainly involved the gray matter, but also some white matter. A magnetic resonance imaging diagnosis for cerebral fat embolism that was induced by oleic acid through the internal carotid artery in cats showed high signal intensity on the T2WI and the DWI within an initial 2 hours, and with a well enhancement on the Gd-enhanced T1WI. Considering cellular edema, cerebrovascular injury and extracellular space widening, we assumed pathologically that cytotoxic and vasogenic edema exists at the same time.

• Investigative Magnetic Resonance Imaging
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• v.14 no.2
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• pp.151-155
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• 2010

Primary hepatic lymphoma is extremely rare, representing less than 1% of all extranodal lymphomas. We report MR imaging features and pathologic correlation of a case of primary hepatic lymphoma. MR images showed a large lobulated mass with gradual contrast enhancement, resembling intrahepatic cholangiocarcinoma. However, both hepatobiliary phase image obtained 20 minutes after injection of hepatocyte specific contrast agent and diffusion-weighted image demonstrated characteristic three layered pattern representing viable lymphoma in the outer layer, tumor necrosis in the middle layer and necrotic hepatic parenchyma in the center.

• Journal of Biomedical Engineering Research
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• v.27 no.2
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• pp.53-58
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• 2006

In this study, transverse relaxation time (T2) measurement and the evaluation of the characteristics of the spectral peak related to stomach tissue metabolites were performed using ex vivo proton magnetic resonance spectroscopic imaging (MRSI) at 1.5-T MRI/S instruments. Thirty-two gastric tissues resected from 12 patients during gastric cancer surgery, of which 19 were normal tissue and 13 were cancerous tissue, were used to measure the $T_2$ of the magnetic resonance spectroscopy (MRS) peaks. The volume of interest data results from the MRSI measurements were extracted from the proper muscle (MUS) layer and the composite mucosa/submucosa (MC/SMC) layer and were statistically analyzed. MR spectra were acquired using the chemical shift imaging (CSI) point resolved spectroscopy (CSI-PRESS) technique with the parameters of pulse repetition time (TR) and echo times (TE) TR/(TE1,TE2)=1500 msec/(35 msec, 144 msec), matrix $size=24{\times}24$, NA=1, and voxel $size=2.2{\times}2.2{\times}4mm^3$. In conclusion, the measured $T_2$ of the metabolite peaks, such as choline (3.21ppm) and lipid (1.33ppm), were significantly decreased (p<0.01 and p<0.05, respectively) in the cancerous stomach tissue.