• Computers and Concrete
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• v.16 no.2
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• pp.287-309
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• 2015

FormWorks-Plus is a generalized public domain user-friendly preprocessor developed to facilitate the process of creating finite element models for structural analysis programs. The lack of a graphical user interface in most academic analysis programs forces users to input the structural model information into the standard text files, which is a time-consuming and error-prone process. FormWorks-Plus enables engineers to conveniently set up the finite element model in a graphical environment, eliminating the problems associated with conventional input text files and improving the user's perception of the application. In this paper, a brief overview of the FormWorks-Plus structure is presented, followed by a detailed explanation of the main features of the program. In addition, demonstration is made of the application of FormWorks-Plus in combination with VecTor programs, advanced nonlinear analysis tools for reinforced concrete structures. Finally, aspects relating to the modelling and analysis of three case studies are discussed: a reinforced concrete beam-column joint, a steel-concrete composite shear wall, and a SFRC shear panel. The unique mixed-type frame-membrane modelling procedure implemented in FormWorks-Plus can address the limitations associated with most frame type analyses.

• Development and Reproduction
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• v.25 no.2
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• pp.113-121
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• 2021

This article aims to introduce German discussion on the approval of the non-invasive prenatal diagnosis (NIPD), which started with the development of PrenaTest^® by LifeCodexx AG. The discussion started with the concern that the non-invasive nature of NIPD, such as PrenaTest^®, may rapidly expand the use and scope of similar tests, thus leading to a new era of eugenics. Based on this concern, the need for clear clinical guidelines on specific indications for NIPD has been suggested. Along the same line, it was discussed whether PrenaTest^® is against the Basic Law prohibiting discrimination on grounds of disability and whether the test is outside the scope of the purpose of gene testing limited by Genetic Diagnosis Act. Through such discussion, the Federal Ministry of Health of Germany established the preconditions for inclusion of NIPD in the German public health insurance system. For this, the German motherhood guideline was amended and the information for the insured persons provided to pregnant women was included in the amended guideline. Such discussion made in Germany provides insight on which points should be considered when various gene testings are accepted in Korea, in which genetic communication has not been systematized yet. In particular, German counseling system for pregnant women will provide valuable insights for Korea where the direction for regulations on abortion has not been established even after the ruling by the Constitutional Court that charges for abortion are against the constitution.

• Toxicological Research
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• v.35 no.4
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• pp.319-330
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• 2019

Adverse drug reactions (ADRs) constitute key factors in determining successful medication therapy in clinical situations. Integrative analysis of electronic medical record (EMR) data and use of proper analytical tools are requisite to conduct retrospective surveillance of clinical decisions on medications. Thus, we suggest that electronic medical recording and human genetic databases are considered together in future directions of pharmacovigilance. We analyzed EMR-based ADR studies indexed on PubMed during the period from 2005 to 2017 and retrospectively acquired 1161 (29.6%) articles describing drug-induced adverse reactions (e.g., liver, kidney, nervous system, immune system, and inflammatory responses). Of them, only 102 (8.79%) articles contained useful information to detect or predict ADRs in the context of clinical medication alerts. Since insufficiency of EMR datasets and their improper analyses may provide false warnings on clinical decision, efforts should be made to overcome possible problems on data-mining, analysis, statistics, and standardization. Thus, we address the characteristics and limitations on retrospective EMR database studies in hospital settings. Since gene expression and genetic variations among individuals impact ADRs, pharmacokinetics, and pharmacodynamics, appropriate paths for pharmacovigilance may be optimized using suitable databases available in public domain (e.g., genome-wide association studies (GWAS), non-coding RNAs, microRNAs, proteomics, and genetic variations), novel targets, and biomarkers. These efforts with new validated biomarker analyses would be of help to repurpose clinical and translational research infrastructure and ultimately future personalized therapy considering ADRs.

• International Journal of Advanced Culture Technology
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• v.10 no.4
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• pp.337-344
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• 2022

The ecological expression of art in modern society takes the harmonious developmental relationship between man and nature as an element and combines it with the various manifestations of painting as an expression of ecological artistic development. The necessary relationship for the harmonious development of nature is accurately articulated, and the ecological changes in people are expressed in integrated materials that inspire human reflection. In the pursuit of material pleasures, mankind is neglectful and indifferent to the environment. The development of composite painting in art and ecology is a process that more reveres the harmony between man and nature as well as satisfying the creative value of the work. After systematic evaluation and research, people have engaged in various structural forms of composite art painting development in the long history of art development, focusing on the integration of environmental and ecological culture.In the process of nature education going through development, the comprehensive practical development of nature education is enhanced and efforts are made to feel new ecological art ideas and new ways of valuing environmental protection. In this paper, an observational study of eco-art will be carried out, starting from the theory of hierarchical division and analyzing the contradictory relationship between man and nature. Recognize nature, understand it and feel it through eco-art painting. The analysis of the contradictory relationship between man and nature is combined with the identification of various types of information that give value to the environmental protection public, and the combination of ecological painting and nature art to achieve an upgrade of the environmental protection idea of the value of painting.

• 한국약용작물학회:학술대회논문집
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• 2006.11a
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• pp.23-39
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• 2006

The application of the knowledge from the Human Genome Project to clinical medicine will be through both industrial drug development and the application of pharmacogenomics (PG) to patient care. The slow uptake of clinical innovations into clinical practice can be frustrating, but understanding the history of acceptance and sustaining medical innovation is critically important to position PG to succeed. This primarily means that PG tests must have legitimacy; they must be thoroughly validated, must be cost-effective, must be widely accepted by medical practitioners, must be supported by public policy, and must have a way of being easily incorporated into current medical practice. They must also lead to actionalble decisions by health care providers for their patients. Innovative PG assays should be tested in the best US laboratories, and reimbursement for testing must be accepted at the federal and state level. The companies providing these PG tests should be capable of supporting the interpretation and use of the test throughout medical practice. Advances such as the addition of PG information to drug labeling and the routine use of validated biomarkers to determine choice of cancer chemotherapy have been made. The PG research community must pay attention to the principles that have been previously described for acceptance and sustaining medical innovations in order for PG to be widely accepted in clinical medical practice.

• International conference on construction engineering and project management
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• 2009.05a
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• pp.883-889
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• 2009

The importance of cost estimate in early stage such has been increasing due to market change and severe competition in construction industry. Because the adjustable budget is only 20% after design stage, most of the crucial decisions to influence cost is made in the early stage. However, in the early stage, the project scope is not defined completely so that estimator has inaccurate information to make critical decision. Therefore, this research suggests the cost estimate method using case-based reasoning. Case-based reasoning is appropriate for the early cost estimating, as it has the strength of rapidity and convenience in cost estimation. This research analyzes 84 actual data of public apartment on the scale of 11~15 stories. In order to extract the most similar case, at the first step this research identifies influence factors and calculates attribute similarity. In case-based reasoning, the most challenging task is determining attribute weight. At the third step, this research calculates case similarity which is aggregated attribute similarity multipled by attribute weight. Finally, extracts the most similar case which has the highest score of case similarity.

• International conference on construction engineering and project management
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• 2022.06a
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• pp.1154-1161
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• 2022

Building Information Modelling (BIM) has evolved into a comprehensive, collaborative method in construction project delivery. Most industrialized and developed countries have made BIM mandatory in the government and public projects, whereas developing countries are embracing and catching up BIM technologies to improve their professional's abilities and reduce claims in the construction projects. However, BIM awareness and professional's competence have become critical in implementing BIM in infrastructure projects in Nepal, particularly hydropower projects. The objectives of this study are to find the BIM awareness among hydropower professionals in Nepal and assess their response. The study used a questionnaire survey to assess the awareness. The results showed that only few professionals (12 percentage in this study) are aware of BIM and its application in Hydropower infrastructures. Majority of the respondents (more than 50%) were interested in BIM trainings and believed BIM implementation in future projects. The study indicated that lack of BIM training and lack of BIM awareness were the top factors affecting BIM implementation in hydropower projects in Nepal. The findings showed that about 66 percent of the respondents who used BIM in their projects mainly used during construction phase. More than 80 percent believed that BIM should be mandated for the hydropower projects in Nepal. The findings presented in this study could promote awareness among different professionals, organization, and construction team and encourage BIM implementation in Hydropower projects. The findings could raise awareness of BIM in Nepal's infrastructure sectors and its invaluable benefits in construction.

• The Journal of Economics, Marketing and Management
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• v.4 no.3
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• pp.12-24
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• 2016

Fraudulent financial reporting practices can have significant consequences for organizations and all stakeholders, as well as, for public confidence in the capital and security markets. In fact, comprehensive, accurate and reliable financial reporting is the bedrock upon which our markets are based. Keen to project a rosy picture of the Satyam to investors, employees and analysts, Mr. Raju (CEO and Chairman) fudged the account books so that it appeared to be a far bigger enterprise, with high profits and fast growth rate, than it actually was. The Satyam fraud has shattered the dreams of different categories of investors, shocked the government and regulators alike, and led to questioning of the accounting practices of statutory auditors and corporate governance norms in India. This is an exploratory study based on secondary sources of information. An attempt has been made to provide an explanation for various intriguing questions about Satyam scam. After thorough investigations by the CBI and SEBI, they have unveiled the methodology by which Satyam fraud was engineered. Finally, we recommend "Fraudulent reporting practices should be considered as a serious crime, and accounting bodies, courts and other regulatory authorities in India need to adopt very strict punitive measures to stop such unethical practices."

• The Journal of Korean Institute of Communications and Information Sciences
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• v.39B no.1
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• pp.17-28
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• 2014

The increase of smartphone users have made mobile carriers offload increasingly congested traffic of 3/4G by providing Wi-Fi hot-spots in the public places such as coffee shops and subway stations. In the traditional authentication in WLAN, the users should convince the service providers that they are valid customers before they use WLAN services. Since the authentication protocol is designed for service providers. Even with the mutual authentication based on the IEEE 802.1X, which is supported by IEEE 802.11 standard, it is difficult to be convinced of that the service providers really have installed the WLAN APs, which users are confronted with. An attacker can install rogue APs that masquerade as legitimate APs by copying the SSID, MAC address, etc. in order to obtain users' private information. In this paper, we introduce a method of authenticating legitimate APs for smartphone users. And we show our proposal can be well utilized for the current Wi-Fi hot-spots as a security plug-in and prove it through our experiments.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.25 no.1
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• pp.153-171
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• 2014

This paper detailed the content and methods of the instructional activities of teacher-librarians in Korea. Using Kuhlthau's levels of education model as a theoretical framework, the study analyzed its data on the direct instructional activities the Korean teacher-librarians reported. The participants included four researchers in school libraries as well as the high school teacher-librarians in Seoul. Written survey were conducted for researchers and teacher-librarians respectively. The results show that there exists a gap between the theoretical emphasis on instructional activities of teacher-librarians and the practice of teacher -librarians in schools, and that the level of instructional activities has not yet advanced fully to the high levels of instructional activities. Future efforts should be made on developing legal as well as educational systems to support advancing the instructional levels of teacher-librarians. Integrating information literacy curricula into the national-level curriculum for public education could be a good example.