The pupose of the present paper is to estimate the effects of constraint condition of pile head, ground condition(dry unit weight. $\gamma_4$) and embedded pile lengths on the behavior of single pile which is embedded in normally consolidated clay. BBperiment functions can be quantified to these effects obtained from the results of model teats. The ground of model tests is normally consolidated( NC ) clay under three kinds of effective vertical stress. The results of the model tests using the steel pile of two different embedded pile length and of free-head and fired-head show that the lateral load-deflection relationship is to be elasto plastic behavior below $\gamma_d/\gamma_{dmax}$: 0.84 and that the reduction of lateral load of beyond maximum lateral load($Q_{max}$) at each model test is significantly time-dependent. In this study, it is shown that the displacement relationship can be fitted to exponential function of time by model best results. The effect of ground conditions on the ultimate and yield lateral load is fitted to exponential function including the ratio of dry unit weight to maximum dry unit weight. When tests by results are compared with those from Broms and Budhu et at., the predicted results are over-estimated about 27-87 ayo. In effectivity of constraint condition of pile head on the lateral load-deflection response, the $Q_{fixed}/Q_{gree}-y/D$ relationship is highly non-linear and fitted to parabolic function.
The main objective of this dissertation is to find out the measurement methods of household work organization and manger style and the quantitative analysis methods of influential factors on household work organization and manager style. Subjects were homemakers living in metropolitan , medium and small cities. Questionnaires were sent to subjects and usable responses were 1139 out of 1239 received questionnaires. Data collected through both preliminary and main survey were analyzed by using frequencies, percentage, analysis of variance, chi-square test and pearson's correlation analysis. Results are as follows; 1) The degree of household work organization was distributed on upper middle level exceeding middle score. Among subsystems of household work such as task assignment , test regularization, task arrangement and task standardization. subjects show the highest positive attitude in task standardization. 2) The characteristics of management in household work have task centered orientation. By the prority of task centered orientation, the order was integrated style. dedicated style. It means that the most ideal style is an integrated style which accounts for one-third of the total homemakers. 3) Household organization's subsystems and household work manager style are related with socio-demographic variables. Integrated style is significantly related with homemaker's employment and having helpers for household work. homemakers who are employed and have helpers for household work exhibit high scores in task assignment and task arrangement. Dedicated style is significantly related with homemaker's age and the number of children. Homemakers who are older and have many children exhibit high scores in task assignment. Related style is significantly related with marriage duration, education level and income level. Homemakers who have a long marriage duration exhibit high scores in task assignment and who have high education and income level exhibit high scores in task regularization. Seperates style is significantly related with homemaker's age m marriage duration an family life cycle. homemakers who ar older, have a long marriage duration and are of late stage in family life cycle exhibit seperated style and high scores in organization. To summarize research findings, household work manger and household work organization are related with family life experiences, and task assignment is an influential variable on manager style. in conclusion, it is evident that household work organization emphasizes efficiency as cognitive component and such organization. Finally it is necessary to broaden this research considered social psychological variables. And also it needs to build household manger style models appropriate fro the characteristics of each style.
In order to produce xylitol with high yield, experiments were carried out to develope xylitol dehydrogenase (XDH) defective m mutant from Pichia stipitis and to investigate the xylit이 fermentation characteristics of mutant strain. After treatment of P s stipitis with EMS, mutant PXM-4 was selected based on the XDH activity and xylitol production capability. Among the tested c cosubstrates, galactose was selected as an adequate cosubstrate on xyl뻐I production of mutant PXM-4. With the increase of galactose concentration, xylitol production was decreased because the transport of xylose into cell was inhibited by g galactose. The optimal concentration of galactose for the production of xylitol using 20 g/L xylose was 20 g/L. Under this c condition, maximum concentration of xylitol and yield were 14.4 g/L and 97%, respectively. In order to prevent the inhibitory e effect of xylose transport by galactose, galactose was fed with low concentration and the concentration of xylitol produced w was increased up to 25 g/L. In the fermentation of corn cob hydrolyzate by mutant PXM-4, xylose was completely converted t to xylit이 with a 100% yield in 4 days culture.
The influence of the relative humidity, the temperature and the velocity of supply air on evaporation rate has been studied with non-boiling forced evaporation system in order to treat very low level radioactive liquid wastes produced from the decontamination and decommissioning activities. Experimental data on the evaporation rate have been obtained with the divers variables and experimental equation of air velocity was also obtained by the correlation of those data. The decontamination factor of this system was also obtained by the experimental data from a simulated liquid waste containing Cs-137 radio isotope ; $DF=10^4$. Since the commercial system will be operated for the treatment of the very low level radioactive liquid waste produced from decontamination & decommissioning of TRIGA Mark-II&III research reactor, the environmental assessment has been conducted to improve the operational safety. Exposure dose rate for an individual member of general public was assessed, and it showed that it was very lower than individual dose limits. The release of radioactivity of radioisotope material (Cs-137) to the environment was assessed, and result showed that it was $4.637{\times}10^{-14}\;{\mu}Ci/cc$.
Journal of the Korean Institute of Landscape Architecture
/
v.33
no.6
s.113
/
pp.98-108
/
2006
The climate of urban area is an unstable type with considerable seasonal variation in precipitation wind speed, and temperature and it grows worse. Besides, ozone is a serious air pollutant in most of large cities. So worldwide, some of large cities are investing in forestry options to offset their climate problems, but lack of information has hindered comparisons of urban un cost effectiveness to other options. This research intends to study the economic benefits of tree shading of 19 parking lots in UCD campus. The economic benefits of tree shading are air conditioning savings, air quality, stormwater run-off, and other benefits. Especially, this study focuses how much the economic benefit of parking lot shading has been increased from 1995 to 2003 year by aerophoto. Some data on dimensions of parking lots and the number, size, tree species, and location of trees around each parking lot was inventoried. Two aerophotos(1995,2003) were used in order to analyze the increasement of tree canopy in 19 parking lots for 8 years. However, increasing coverage of trees and managing them for healthy growth would not be sufficient for avoiding adverse impacts by future climate change. Additional measures should be followed such as an increase of energy use efficiency and development of substitute energy. For example, coverage of trees help to save cooling energy by blocking solar radiation reaching parking cars and building structures through shading, and creating cool micro-climates through evapotranspiration. They also reduce heating demand by decreasing air infiltration and heat conduction out of the interior of buildings. Proper arrangement of vegetation over the parking lots can reduce cooling and heating costs. So proper planting design around hard space paving including species selection and location can significantly save cooling and heating energy. And a reduction in car and building's heating and cooling costs results in the reduction in energy demand which causes to emissions of air pollutants. Total increased tree canopy from 1995 to 2003 is $8,470.45m^2$ and the economic benefits is US$ 5,282.10. The economic benefit of one tree has been US$ 7.21 for 8 years. And an annually increased benefit is US$ 0.9 per a tree. If this kind of study is applied to studying the economic benefits of tree canopy in parking lots of Korea, it could result in guidelines of tree planting of parking lots. Because the trees selected for planting in parking lots were not suitable for an environment, the guidelines should contain a recommended list of trees. The guidelines should propose the shading percentage of parking lot when we plan a parking lot and contain the maintenance of trees in order to maximize the economic benefits of tree canopy.
Journal of the Korean Society of Food Science and Nutrition
/
v.43
no.6
/
pp.909-915
/
2014
This study was carried out to evaluate the genotoxicity of imported oranges irradiated with ionizing energy (0.5 and 1 kGy). In bacterial reversion assays with Salmonella Typhimurium TA98, TA100, TA1535, and TA1537, imported oranges irradiated with ionizing energy (0.5 and 1 kGy) showed no significant increase in the number of revertant colonies in both the absence and presence of the S9 metabolic activation system. In chromosomal aberration tests with Chinese hamster ovary (CHO) cells, imported oranges irradiated with ionizing energy (0.5 and 1 kGy) showed no increase in the frequency of chromosomal aberrations. In in vivo mouse micronucleus assay, imported oranges irradiated with ionizing energy (0.5 and 1 kGy) showed no increase in the frequency of polychromatic erythrocytes with micronucleus. These results indicate that imported oranges irradiated with ionizing energy (0.5 and 1 kGy) showed no genotoxic effects under these experimental conditions.
Journal of the Korean Society of Food Science and Nutrition
/
v.42
no.8
/
pp.1167-1174
/
2013
Cancer cells exhibit increased demand for glutamine-derived carbons to support anabolic processes. Indeed, the spectrum of glutamine-dependent tumors and the mechanisms through which glutamine supports cancer metabolism remain areas of active investigation. In the present study, we investigated the effects of glutamine deprivation on the correlation between tightening of tight junctions (TJs) and anti-invasive activity in human prostate carcinoma LnCap cells. Glutamine deprivation markedly inhibited cell motility and invasiveness in a time-dependent manner. The anti-invasive activity of glutamine deprivation was associated with an increased tightness of the TJ, which was demonstrated by an increase in transepithelial electrical resistance (TER). The activities of matrix metalloproteinase (MMP)-2 and MMP-9 were inhibited in a time-dependent fashion by glutamine deprivation, which was correlated with a decrease in expression of their mRNA and proteins and up-regulation of tissue inhibitors of metalloproteinases (TIMPs) expression. Furthermore, glutamine deprivation repressed the levels of the claudin family members, which are major components of TJs that play a key role in the control and selectivity of paracellular transport. Moreover, the levels of E-cadherin, a type I transmembrane glycoprotein, and snail, an epithelial to mesenchymal transition regulator and zinc finger transcription factor, were markedly modulated by glutamine deprivation. Taken together, these findings suggest that TJs and MMPs are critical targets of glutamine deprivation-induced anti-invasion in human prostate carcinoma LnCap cells.
This study examined the effects of pre-slaughter fasting, chasing stress and chiller ageing on objective meat quality, and their relations to the proteome profile of longissimus muscle using 20 male Korean native black pigs. Treatments were composed of two levels of pre-slaughter feed withdrawal, two levels of pre-slaughter stress and four chiller ageing times. A 15 min chasing stress immediately prior to slaughter significantly (p<0.05) decreased detectable levels of $\mu$-calpain activity during rigor development and chiller ageing, but did not have any direct effect on objective meat quality. On the other hand, pigs fed until the morning of slaughter resulted in significantly (p<0.05) higher hunter L* value and cooking loss than those which received an 18 h feed withdrawal prior to slaughter. Cooking loss and hunter L* value were constant during 7 d of chiller ageing, followed by significant increases at 14 d. The fed animals showed a significantly (p<0.05) higher hunter a* value at both 3 and 7 d, while the other group maintained a stable redness for 7 d. WB-shear force was not affected by the pre-slaughter treatments, but had significant (p<0.05) linear reduction from 1 to 7 d. A gelbased proteome analysis was performed on selected animals for low and high hunter L* values at 1 d. Ten and five spots had greater than two-fold spot densities for the low and high hunter L* groups, respectively. The ten spots included chain A, deoxyribounclease I complex with actin, heat shock protein 27 kDa, a protein similar to cardiac $Ca^{2+}$ release channel, and myosin heavy chain, while the five spots included chain A aldehyde dehydrogenase, glycerol-3 phosphate dehydrogenase, and hemoglobin alpha chain. In general, feeding until the morning of slaughter resulted in more desirable meat color, but appeared to reduce palatability due to increased cooking loss. Proteome analysis demonstrated that various proteins were concomitantly involved in the determination of final meat color. The most noticeable observation in the current study was that various isoforms for a particular protein differed in degradation and/or expression rate depending on meat quality.
Kita, K.;Shibata, T.;Aman Yaman, M.;Nagao, K.;Okumura, J.
Asian-Australasian Journal of Animal Sciences
/
v.15
no.12
/
pp.1760-1764
/
2002
In order to elucidate the physiological function of circulating IGF-I on muscle protein synthesis in the chicken under malnutritional conditions, we administrated recombinant chicken IGF-I using a osmotic mini pump to fasted young chickens and measured the rate of muscle protein synthesis and plasma metabolite. The pumps delivered IGF-I at the rate of $22{\mu}g/d\{300{\mu}g{\cdot}(kg\;body\;weight{\cdot}d)^{-1}\}$. Fractional rate of protein synthesis in the muscle was measured using a large dose injection of L-[$2,6-^3H$]phenylalanine. Constant infusion of chicken IGF-I did not affect plasma glucose level. Significant interaction between dietary treatment and IGF-I infusion was observed in plasma NEFA and total cholesterol concentrations. When chicks were fasted, IGF-I infusion decreased plasma NEFA and total cholesterol concentrations. On the other hand, IGF-I administration did not affect plasma levels of both metabolites. Fasting reduced plasma triglyceride concentration significantly. IGF-I infusion also decreased the level of plasma triglyceride. Plasma IGF-I concentration of young chickens was halved by fasting for 1 d. IGF-I infusion using an osmotic minipump for 1 d increased plasma IGF-I concentration in fasted chicks to the level of fed chicks. Fasting decreased body weight and the loss of body weight was significantly ameliorated by IGF-I infusion. There was a significant interaction between dietary treatment and IGF-I infusion in the fractional rate of breast muscle protein synthesis. There was no effect of IGF-I infusion on muscle protein synthesis in fed chicks. Muscle protein synthesis reduced by fasting was ameliorated by IGF-I infusion, but did not reach to the level of fed control. Muscle weight of fasted chicks infused with IGF-I was similar to fasted birds without IGF-I infusion, which suggests that muscle protein degradation would be increased by IGF-I infusion as well as protein synthesis in fasted chicks.
Four hundred and fifty tilapias ($6.77{\pm}0.23$ g) were assigned randomly to six groups to evaluate the feasibility of the tested antibacterial peptides (ABPs) and oligosaccharides as substitutes for antibiotics. The control group was fed with a commercial tilapia diet; other five groups were fed with the same commercial diet supplemented with konjac glucomannan (KGLM), cluster bean galactomannan (CBGAM), and three animal intestinal ABPs derived from chicken, pig and rabbit at 100 mg/kg respectively. After 21 days of feeding, growth, disease resistance, and in vivo anti-adherence were determined. Furthermore, the inhibitory effect of tested agents on adhesion of Aeromonas veronii biovar sobria (A.vbs) strain BJCP-5 to tilapia enteric epithelia in vitro was assessed by cell-ELISA system. As a result, the tested agents supplemented at 100 mg/kg show significant benefit to tilapia growth and disease resistance (p<0.05), and the benefit may be correlated with their interfering in the contact of bacteria with host mucosal surface. Although none of the tested agents did inhibit the growth of BJCP-5 in tryptic soy broth at $100{\mu}g/ml$, all of them did inhibit the adhesion of A.vbs to tilapia enteric epithelia in vivo and in vitro. In vitro mimic assays show that three ABPs at low concentrations of $25{\mu}g/ml$ and $2.5{\mu}g/ml$ have the reciprocal dose-dependent anti-adherence effect. The inhibition of ABPs may be correlated with a cation bridging and/or receptor-ligand binding, but not with hydrophobicity. The KGLM and CBGAM inhibited the adherence of BJCP-5 to tilapia enteric epithelia with dose-dependent manner in vitro, and this may be through altering bacterial hydrophobicity and interfering with receptor-ligand binding. Our results indicate that the anti-adherence of the tested ABPs and oligosaccharides may be one of the mechanisms in promoting tilapia growth and resistance to A.vbs.
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