• Title/Summary/Keyword: M_2\

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Influence of Detailed Structure and Curvature of Woven Fabric on the Luminescence Effect of Wearable Optical Fiber Fabric (직물의 세부 구조 및 굴곡이 웨어러블 광섬유의 발광 효과에 미치는 영향)

  • Yang, Jin-Hee;Cho, Hyun-Seung;Kwak, Hwy-Kuen;Oh, Yun-Jung;Lee, Joo-Hyeon
    • Science of Emotion and Sensibility
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    • v.21 no.4
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    • pp.55-62
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    • 2018
  • The two main requirements of wearable optical fiber fabrics are that they must presuppose a high degree of flexibility and they must maintain the luminance effect in both flat and bent conformations. Therefore, woven optical fiber fabrics that satisfy the above conditions were developed by both weaving and by using computer embroidery. First, we measured the brightness of the wearable optical fiber fabric in the flat state at a total of 10 measurement points at intervals of 1 cm. Second, the wearable optical fiber fabric was placed horizontally on the forearm, where three-dimensional bending occurs, and the luminance values were recorded at the same 10 measurement points. For the woven fabric in the flat state, the maximum, minimum, average, and standard deviation luminance values were $5.23cd/m^2$, $2.74cd/m^2$, $3.56cd/m^2$, and $1.11cd/m^2$, respectively. The corresponding luminance values from the bent forearm were $7.92cd/m^2$ (maximum), $2.37cd/m^2$ (minimum), $4.42cd/m^2$ (average), and $2.16cd/m^2$ (standard deviation). In the case of the computer-embroidered fabric, the maximum, minimum, average, and standard deviation luminance values in the flat state were $7.56cd/m^2$, $3.84cd/m^2$, $5.13cd/m^2$, and $1.04cd/m^2$, respectively, and in the bent forearm state were $9.6cd/m^2$, $3.63cd/m^2$, $6.13cd/m^2$, and $2.26cd/m^2$, respectively. Therefore, the computer-embroidered fabric exhibited a higher luminous effect than the woven fabric because the detailed structure reduced light-loss due to the backside fabric. In both types of wearable optical fiber fabric the luminance at the forearm was 124% and 119%, respectively, and the light emitting effect of the optical fiber fabric was maintained even when bent by the human body. This is consistent with the principle of Huygens, which defines the wave theory of light, and also the Huygens-Fresnel-Kirchhoff principle, which states that the intensity of light increases according to the magnitude of the angle of propagation of the light wavefront (${\theta}$).

Expression and Localization of ATF4 Gene on Oxidative Stress in Preimplantation Mouse Embryo (생쥐 착상전 배아에서 산화적 스트레스에 의한 ATF4 유전자의 발현과 존재 부위)

  • Na, Won-Heum;Kang, Han-Seung;Eo, Jin-Won;Gye, Myung-Chan;Kim, Moon-Kyoo
    • Development and Reproduction
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    • v.10 no.2
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    • pp.105-113
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    • 2006
  • Reactive oxygen species(ROS) generated in cellular metabolism have an effect on cell maturation and development. In human reproductive tract, oxidative injury by ROS may induce female infertility. Also, oxidative injury may be responsible for developmental retardation and arrest of mammalian preimplantation embryos. Activating transcription factor 4(ATF4) is a member of the cyclic-AMP response element-binding(CREB) familiy of basic region- leucine zipper(bZip). ATF4 is known to regulate stress response to protect cell from various stress factors and inducer of apoptisis. The purpose of this study was to investigate whether ATF4 is involved in the defensive mechanism in oxidative stress condition during the development of mouse preimplantation embryos. To verify the expression of ATF4 in oxidative stress condition, 2-cell stage embryos were cultured in HTF media containing 0.1mM, 0.5mM or 1mM hydrogen peroxide($H_2O_2$) for 1hr(2-cell), 8hr(4-cell), 17hr(8-cell), 24hr(morula), 48hr(early blastocyst) or 64hr(late blastocyst). The developmental rate decreased in the 0.1mM $H_2O_2$ treated group compared with control group. In embryos treated with 0.5mM and 1mM $H_2O_2$ showed 2-cell block. As a results of the semi-quantitative RT-PCR analysis of SOD1, ATF4 and Bax gene expression, SOD1, ATF4 and Bax genes were increased in 0.1mM, 0.5mM, 1mM $H_2O_2$ treated groups compared with control group. In 2-cell embryos, expression of SOD1, ATF4 and Bax genes were notably increased in 0.1mM, 0.5mM, 1mM $H_2O_2$ treated groups compared with control group. Immunofluorescence analysis showed that ATF4 protein was localized at the cytoplasm of preimplantation embryos. The increase in ATF4 immunoreactivety was observed in the 0.1mM, 0.5mM, 1mM $H_2O_2$ treated groups compared with control group. It suggests that oxidative stress by $H_2O_2$ induces expression of ATF4 and may be involved in protection mechanism in preimplantation embryos from oxidative injury.

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In vitro Metabolism of Pentoxifylline Metabolite M-l in Human Liver Microsomes (인체 간 microsome에서 pentoxifylline 대사체 M-1의 시험관내 대사)

  • 신혜순
    • YAKHAK HOEJI
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    • v.43 no.6
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    • pp.834-842
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    • 1999
  • The metabolism and pharmacokinetics of M-l, which is metabolite of pentoxifylline, have been studied in human liver microsomes. Biphasic kinetics was observed from the Eadie-Hofstee plot for the formation of both metabolites of M-l. For the kinetics of pentoxifylline, mean values of $V_{max1}{\;}and{\;}V_{max2}$ were 1,648 and 5,622 nmol/min/mg protein, and the estimated values of $K_{ml}{\;}and{\;}K_{m2}$ were 0.180 and 4.829 mM, respectively. For M-3, mean values of $V_{max1}{\;}and{\;}V_{max2}$ were 0.062 and 0.491 nmol/min/mg protein, and estimated values of $K_{ml}{\;}and{\;}K_{m2}$ were 0.025 and 1.216 mM. The formations of pentoxifylline and M-3 from M-1 were indentified by using several selective inhibitors of cytochrome P450 isoformes at 0.05-5 mM concentration of M-1 in human liver microsomes. For the analysis of low (0.05 mM) concentration of M-1, where the affinity was expected as low, indicated that CYPlA2 and CYP3A4 were major P450 isoforms responsible for pentoxifylline and M-3 formation. CYP3A4 and CYP2A6 appeared to be P450 isoforms responsible for M-3 formation at high (5 mM) concentration of M-1.

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Comparison of Various Single Chemical Extraction Methods for Predicting the Bioavailability of Arsenic in Paddy Soils

  • Go, Woo-Ri;Jeong, Seon-Hee;Kunhikrishnan, Anitha;Kim, Gyeong-Jin;Yoo, Ji-Hyock;Cho, Namjun;Kim, Kwon-Rae;Kim, Kye-Hoon;Kim, Won-Il
    • Korean Journal of Soil Science and Fertilizer
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    • v.47 no.6
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    • pp.464-472
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    • 2014
  • The Codex Committee of Contaminants in Food (CCCF) has been discussing a new standard for arsenic (As) in rice since 2010 and a code of practice for the prevention and reduction of As contamination in rice since 2013. Therefore, our current studies focus on setting a maximum level of As in rice and paddy soil by considering bioavailability in the remediation of As contaminated soils. This study aimed to select an appropriate single chemical extractant for evaluating the mobility of As in paddy soil and the bioavailability of As to rice. Nine different extractants, such as deionized water, 0.01 M $Ca(NO_3)_2$, 0.1 M HCl, 0.2 M $C_6H_8O_7$, 0.43 M $HNO_3$, 0.43 M $CH_3COOH$, 0.5 M $KH_2PO_4$, 1 M HCl, and 1 M $NH_4NO_3$ were used in this study. Total As content in soil was also determined after aqua regia digestion. The As extractability of the was in the order of: Aqua regia > 1 M HCl > 0.5 M $KH_2PO_4$ > 0.43 M $HNO_3$ > 0.2 M $C_6H_8O_7$ > 0.1 M HCl > 0.43 M $CH_3COOH$ > deionized water > 1 M $NH_4NO_3$ > 0.01 M $Ca(NO_3)_2$. Correlation between soil extractants and As content in rice was in the order of : deionized water > 0.01 M $Ca(NO_3)_2$ > 0.43 M $CH_3COOH$ > 0.1 M HCl > 0.5 M $KH_2PO_4$ > 1 M $NH_4NO_3$ > 0.2 M $C_6H_8O_7$ > 0.43 M $HNO_3$ > 1M HCl > Aqua regia. BCF (bioconcentration factor) according to extractants was in the order of : 0.01M $Ca(NO_3)_2$ > 1 M $NH_4NO_3$ > deionized water > 0.43 M $CH_3COOH$ > 0.1 M HCl > 0.43 M $HNO_3$ > 0.2 M $C_6H_8O_7$ > 0.5 M $KH_2PO_4$ > 1 M HCl > Aqua regia. Therefore, 0.01 M $Ca(NO_3)_2$ ($r=0.78^{**}$) was proven to have the greatest potential for predicting As bioavailability in soil with higher correlation between As in rice and the extractant.

Effects on G2/M Phase Cell Cycle Distribution and Aneuploidy Formation of Exposure to a 60 Hz Electromagnetic Field in Combination with Ionizing Radiation or Hydrogen Peroxide in L132 Nontumorigenic Human Lung Epithelial Cells

  • Jin, Hee;Yoon, Hye Eun;Lee, Jae-Seon;Kim, Jae-Kyung;Myung, Sung Ho;Lee, Yun-Sil
    • The Korean Journal of Physiology and Pharmacology
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    • v.19 no.2
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    • pp.119-124
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    • 2015
  • The aim of the present study was to assess whether exposure to the combination of an extremely low frequency magnetic field (ELF-MF; 60 Hz, 1 mT or 2 mT) with a stress factor, such as ionizing radiation (IR) or $H_2O_2$, results in genomic instability in non-tumorigenic human lung epithelial L132 cells. To this end, the percentages of G2/M-arrested cells and aneuploid cells were examined. Exposure to 0.5 Gy IR or 0.05 mM $H_2O_2$ for 9 h resulted in the highest levels of aneuploidy; however, no cells were observed in the subG1 phase, which indicated the absence of apoptotic cell death. Exposure to an ELF-MF alone (1 mT or 2 mT) did not affect the percentages of G2/M-arrested cells, aneuploid cells, or the populations of cells in the subG1 phase. Moreover, when cells were exposed to a 1 mT or 2 mT ELF-MF in combination with IR (0.5 Gy) or $H_2O_2$ (0.05 mM), the ELF-MF did not further increase the percentages of G2/M-arrested cells or aneuploid cells. These results suggest that ELF-MFs alone do not induce either G2/M arrest or aneuploidy, even when administered in combination with different stressors.

A Conversion of AFm Phases by Addition of CaCO3, CaCl2 and CaSO4 · 2H2O (CaCO3, CaCl2 및 CaSO4 · 2H2O 첨가에 의한 AFm상의 변화)

  • 이종규;추용식
    • Journal of the Korean Ceramic Society
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    • v.40 no.1
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    • pp.24-30
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    • 2003
  • A formation and conversion of AFm phases decisively play role in the hydration, hardening and corrosion processes of various cement. In this study, the conversion of Alumino-Ferrite Monohydrates(AFm) phases under the addition of $CaCO_3,;CaCl_2;and;CaSO_4{cdot}2H_2O$was investigated by the XRD quantitative analysis. The thypical AFm phases are $M_S(monosulfoaluminate),;M_C(monocarboaluminate);and;M_{Cl}(monochloroaluminate and also Called Friedel's salts)$in this cementitious system, The conversion reaction were not occurred in $M_C-CaCO_3,;M_{Cl}-CaCO_3$ and $M_{Cl}-CaCl_2$system. However, in $M_S-CaCO_3$ system, ettringite and $monocarboaluminate(M_C)$ were formed. In $M_S-CaCl_2;system;M_S$ was transformed to Friedel's $salts(M_{Cl})$ and ettringite was formed. In the case of $CaSO_4{cdot}2H_2O$ addition, all AFm $phases(M_S,;M_C;and;M_{Cl})$ were transformed to ettringite. The order of stabilization of AFm phases under $CaCO_3,;CaCl_2;and;CaSO_4{cdot}2H_2O$ was as follows : $M_S< M_C

Metal-Dinitrosyl Complexes(III) : Synthesis and Structural Study of Homo-, Hetero-dinuclear Molybdenum and Tungsten Complexes, $[Cl(phen)(NO)_2M({\mu}-pyz)M'(NO)_2(phen)Cl][ClO_4]_2 $(phen = 1,10-phenanthroline, pyz = pyrazine) (금속-디니트로실 착물 (제 3 보) : 몰리브덴과 텅스텐의 호모 및 헤테로 이핵 착물, $[Cl(phen)(NO)_2M({\mu}-pyz)M'(NO)_2(phen)Cl][ClO_4]_2 (phen=1,10-phenanthroline,\;pyz=pyrazine)$의 합성 및 구조에 대한 연구)

  • Sang-Oh Oh;Seong-Jong Mo
    • Journal of the Korean Chemical Society
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    • v.37 no.7
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    • pp.655-661
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    • 1993
  • The neutral monomeric compounds $[Mo(NO)_2Cl_2(phen)]$ and $[W(NO)_2Cl_2(phen)]$ (phen= 1,10-phenanthroline) have been prepared by reactions of polymeric compounds $[{Mo(NO)_2Cl_2}n],\;[{W(NO)_2Cl_2}n]$ with chelate ligands. Additions of one equivalent of silver(I) perchlorate to these cis-dinitrosyl compounds in acetone solution produce $[Mo(NO)_2(phen)(S)Cl][ClO_4]\;and\;[W(NO)_2(phen)(S)Cl][ClO_4]$ (S = acetone). The homo- and hetero-dinuclear complexes, $[Cl(phen)(NO)_2M(pyz)M'(NO)_2(phen)Cl][ClO_4]_2$ (M = Mo, W) and $[Cl(phen)(NO)_2M(pyz)M'(NO)_2(phen)Cl][C1O_4]_2$ (M = Mo, M' = W) have been prepared by these monocationic complexes with pyrazine ligand respectively. These complexes characterized by elemental analysis, $1^H-\;and\;^{13}C-NMR$, infrared, and UV-visible spectroscopy are reported. The spectral data indicate that homo- and hetero-dinuclear complexes were symmetrical structures of $C_{2v}$.

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GROUP-FREENESS AND CERTAIN AMALGAMATED FREENESS

  • Cho, Il-Woo
    • Journal of the Korean Mathematical Society
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    • v.45 no.3
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    • pp.597-609
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    • 2008
  • In this paper, we will consider certain amalgamated free product structure in crossed product algebras. Let M be a von Neumann algebra acting on a Hilbert space Hand G, a group and let ${\alpha}$ : G${\rightarrow}$ AutM be an action of G on M, where AutM is the group of all automorphisms on M. Then the crossed product $\mathbb{M}=M{\times}{\alpha}$ G of M and G with respect to ${\alpha}$ is a von Neumann algebra acting on $H{\bigotimes}{\iota}^2(G)$, generated by M and $(u_g)_g{\in}G$, where $u_g$ is the unitary representation of g on ${\iota}^2(G)$. We show that $M{\times}{\alpha}(G_1\;*\;G_2)=(M\;{\times}{\alpha}\;G_1)\;*_M\;(M\;{\times}{\alpha}\;G_2)$. We compute moments and cumulants of operators in $\mathbb{M}$. By doing that, we can verify that there is a close relation between Group Freeness and Amalgamated Freeness under the crossed product. As an application, we can show that if $F_N$ is the free group with N-generators, then the crossed product algebra $L_M(F_n){\equiv}M\;{\times}{\alpha}\;F_n$ satisfies that $$L_M(F_n)=L_M(F_{{\kappa}1})\;*_M\;L_M(F_{{\kappa}2})$$, whenerver $n={\kappa}_1+{\kappa}_2\;for\;n,\;{\kappa}_1,\;{\kappa}_2{\in}\mathbb{N}$.

$H_2$ $O_2$ Resistance of Escherichia coli That Expresses Acetyl Xylan Esterase of Streptomyces coelicolor A3(2) (Streptomyces coelicolor A3(2)의 Acetyl Xylan Esterase를 발현하는 Escherichia coli의 과산화수소 저항성)

  • Kim Jae-heon;Choi Won-ill;Youn Seock-won;Jung Sang Oun;Oh Chung-Hun
    • Korean Journal of Microbiology
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    • v.40 no.3
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    • pp.232-236
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    • 2004
  • We investigated hydrogen peroxide resistance of Escherichia coli possessing acetyl xylan esterase(AxeA) of Streptomyces coelicolor A3(2). The induction of AxeA production by isopropyl-$\beta$-thiogalactoside was confirmed by SDS-polyacrylamide gel electrophoresis. The differences in growth between induced and non-induced E. coli were determined by the changes in optical density of cultures after hydrogen peroxide treatment The lethal effect of hydrogen peroxide was observed for non-induced cultures at all concentrations tested in this study (lmM, 2.5mM and 5mM). However, cultures induced for AxeA production resisted the lethal effect, except at 5mM where cells were killed irrespective of the AxeA production. The axeA induction increased survival against 1.5mM hydrogen peroxide from 59% to 74%. In addition, AxeA producing E. coli showed increased survival at $45^{\circ}C$, near maximum growth temperature. Therefore, it was concluded that AxeA conferred a cross-resistance upon the bacterium against both oxidative- and heat stress.

M2M Architecture: Can It Realize Ubiquitous Computing in Daily life?

  • Babamir, Seyed Morteza
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.6 no.2
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    • pp.566-579
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    • 2012
  • Ubiquitous computing called pervasive one is based on the thought of pervading ability of computation in daily life applications. In other words, it aims to include computation in devices such as electronic equipment and automobiles. This has led to disengagement of computers from desktop form. Accordingly, the notice in ubiquitous computing being taken of a world steeped in remote and wireless computer-based-services. Handheld and wearable programmed devices such as sense and control appliances are such devices. This advancement is rapidly moving domestic tasks and life from device-and-human communication to the device-and-device model. This model called Machine to Machine (M2M) has led to acceleration of developments in sciences such as nano-science, bio-science, and information science. As a result, M2M led to appearance of applications in various fields such as, environment monitoring, agricultural, health care, logistics, and business. Since it is envisaged that M2M communications will play a big role in the future in all wireless applications and will be emerged as a progressive linkage for next-generation communications, this paper aims to consider how much M2M architectures can realize ubiquitous computing in daily life applications. This is carried out after acquainting and initiating readers with M2M architectures and arguments for M2M. Some of the applications was not achievable before but are becoming viable owing to emergence of M2M communications.