• Title/Summary/Keyword: MUM1

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Transmission Grating Formation in High Refractive-index Amorphous Thin Films Using Focused-Ion-Beam Lithography (접속이온빔 리소그라피를 이용한 고굴절 비정질 박막 투과 격자 형성)

  • Shin, Kyung;Kim, Jin-Woo;Park, Jeong-Il;Lee, Hyun-Yong;Lee, Young-Jong;Chung, Hong-Bay
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.50 no.1
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    • pp.6-10
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    • 2001
  • In this study, we investigated the optical properties of sub-wavelength a-Si thin film transmission gratings, especially the polarization effect, the phase difference and the birefringence by using linearly polarized He-Ne laser beam (632.8nm). The a-Si transmission grating of the thickness $of < 0.1 \mum$ with four-type period($\Lambda = 0.4 \mum and 0.6 \mum$ for sub-wavelength and $\Lambda = 1.0 \mum and 1.4 \mum$ for above-wavelength) on quartz substrates have been fabricated using 50 KeV Ga+ Focused-Ion-Beam(FIB) Milling and $CF_4$Reactive-Ion-Etching(RIE) method. Finally, we obtained the trating array of a-Si thin film with a period $0.4 \mum, 0.6 \mum, 1.0 \mum, 1.4 \mum$ which have nearly equal finger spacing and width, sucessfully. Especially, for gratings with $\Lambda = 0.6 \mum(linewidth=0.25 \mum, linespace=0.35\mum), the \etamax at \theta_в=17.0^{\circ}$ is estimated to be 96%. As the results, we believe that the sub-wavelength grating arrayed a-Si thin film has the applicability as the optical device and components.

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Design and fabrication of the $1.3/1.55\mum$ WDM coupler with the PSG waveguide films (PSG 광도파박막을 이용한 $1.3/1.55\mum$ WDM coupler의 설계 및 제작)

  • 전영윤;김한수;이용태;이형종
    • Korean Journal of Optics and Photonics
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    • v.6 no.4
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    • pp.310-316
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    • 1995
  • We designed the $1.3/1.55\mum$ WDM directional coupler and its coupling length was calculated with the variation of the two waveguide's core separation and other variables by the Fourier transformed scalar wave equation. We deposited the PSG films for optical waveguide by low pressure chemical vapor deposition and fabricated the WDM coupler using the laser lithography and $CF_4/O_2$ reactive ion etching process. A V -groove which was made to support and fix the optical fiber is fabricated on Si substrate by chemical etching. The WDM coupler and the V-groove are connected using UV curing epoxy. We found that propagation mode of each port of WDM coupler is single mode and maximum extinction ratio between two out ports is 6 dB for $1.3.\mum$, and 12 dB for $1.55\mum$. /TEX>.

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A Study on the Design of Laterally Tilted SCH-SLD with Window Region (윈도우 영역을 갖는 측방향으로 경사진 SCH-SLD의 설계에 관한 연구)

  • 황상구;김정호;김운섭;김동욱;안세경;홍창희
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.5 no.4
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    • pp.777-790
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    • 2001
  • Theoretical analyses have been tried to design high power and stable operating SLD at 1.55${\mu}{\textrm}{m}$ wavelength range which is the lowest absorption wavelength in optical fiber. The materials of active layer and SCH layer were chosen as conventional In1-xGaxAsyPl-y quaternary composition systems. From the transverse mode and the lateral mode analyses of waveguide, the optical power distributions and the optical confinement factor have been studied for single-mode high power operation. According to these analyses, it was calculated the composition and the thickness of SCH layer to obtain the maximum optical confinement factor. In order to obtain low values of the reflectivity, we used the window region and the lateral tilted angle between tile active region and window region. And the reflectivity of SLD was calculated with the gaussian beam approximation and mode analysis. From these researches, it was confirmed for several results to fabricate the efficient and stable SLD. In case of using $1.3\mum$, InGaAsP SCH layer, the layer thickness was obtained $0.08\mum$, to get the maximum optical confinement factor. Using $0.2\mum$, active layer thickness and $0.08\mum$, SCH layer thickness, the window region length is about $100\mum$ without An coating, $10\mum$ in 1% AR coating to obtain about 10-4 reflectivity. When the tilted angle is about $10~15^{\circ}$, the reflectivity is about 10-3. From these results, if the window region length and tilted angle were controlled appropriately in given device structure, it was confirmed that it is possible to fabricate the stable SLD without AR coating analytically.

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Characteristics of Er-Doped Fiber Laser on Resonator Reflectivities and Pump Power (공진기 반사율과 펌프 파워에 따른 어븀 광섬유 레이저의 특성)

  • 박서연;이학규;김경헌;이동한
    • Korean Journal of Optics and Photonics
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    • v.5 no.2
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    • pp.286-290
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    • 1994
  • Lasing characteristics of an Er-doped fiber laser have been investigated at various conditions of resonator reflectivities and pump powers. Variation of the laser wavelength with various mirror reflectivities has been compared with the theoretical analysis based on absorption, gain spectra, and resonator parameters. The maximum slope efficiency of 38% was obtained with the resonator's mirror reflectivities of 100% and 4% on both sides, and the threshold powers were varied from 7.8 mW to 5.6 mW, and lasing wavelengths were varied $1.532\mum to 1.563\mum and 1.558 \mum to 1.570 \mum$ for 6 and 15.8 mlong Er-doped fiber, respectively, as the resonator reflectivities were changed from 0.0016 to 0.9.to 0.9.

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The Study of Analog CMOS Process Technology (아날로그 CMOS 공정기술 연구)

  • No, Tae-Mun;Lee, Dae-U;Kim, Gwang-Su;Gang, Jin-Yeong
    • Electronics and Telecommunications Trends
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    • v.10 no.1 s.35
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    • pp.1-17
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    • 1995
  • 본 연구에서는 아날로그 CMOS IC 제조를 위한 CMOS 소자기술 및 수동소자 기술인, 다결정실리콘 저항과 다결정실리콘(I)/산화막/다결정실리콘(II) 구조를 가진 커패시터의 공정기술을 개발하였다. 아날로그 CMOS 공정기술은 디지털 CMOS 공정에서 다결정실리콘 저항과 커패시터 공정이 추가됨으로씨 발생할 수 있는 CMOS 소자특성의 변화를 최소화하는 데 중점을 두어 개발하였다. 최종적으로 개발된 $1.2\mum$ 아날로그 CMOS 공정을 이용하여 10 비트 ADC 및 DACIC를 제작한 후 정상적인 동작을 확인함으로써, $1.2\mum$ 아날로그 CMOS 공정에 의한 아날로그 IC 제작의 응용 가능성을 검증하였다. 개발된 $1.2\mum$ 아날로그 CMOS 공정은 향후 $0.8\mum$ 아날로그 CMOS IC 개발에 크게 기여할 것으로 기대된다.

Evaluation of BCL6 and MUM1 Expression in Patients with Diffuse Large B cell Lymphoma and their Correlations with Staging and Prognosis in Iran

  • Rahimi, Hossein;Jafarian, Amirhossein;Samadi, Alireza;Meamar, Bahram;Rahmani, Shaghayegh
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.1
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    • pp.83-86
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    • 2015
  • Background: Diffuse large B-cell lymphoma (DLBCL) is the most common form of non-Hodgkins lymphoma (NHL), accounting for approximately 25% of NHL cases. The aim of this study was to evaluate the association between the BCL6 and MUM1 gene expression and patient prognosis and stage. Materials and Methods: After ethical approval, in a cross-sectional study, tissue samples of 80 patients with diffuse large B-cell lymphoma were analyzed for BCL6 and MUM1 gene expression. Immunohistochemical staining was performed with division into categories of 0-5%, 5-25%, 26-50%, 51-75% and more than 75%. Other clinical and histological information such as lymph node involvement, T-stage, B symptoms and patient outcome were also recorded. Data were analyzed with SPSS version 16 and a P-value less than 0.05 was considered significant. Results: The patient mean age was $46.9{\pm}10.5$ years ($47.6{\pm}10.7$ and $46.1{\pm}9.6$ for males and females, respectively). A significant association was seen between lymphoma stage and BCL6 (p=0.045) but not MUM1 expression (p=0.09). However, the latter was associated with mortality (p=0.006) as was also the BCL6 level (p=0.006). Conclusions: : Overexpression of MUM1 and BCL6 is associated with poor prognosis in patients with diffuse large B-cell lymphoma.

A Study on the Concentration and Light Extinction of Atmospheric Aerosol in Seoul (서울 대기 에어로솔의 농도와 광소산에 관한 연구)

  • 김필수;오미석;김의훈
    • Journal of Korean Society for Atmospheric Environment
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    • v.7 no.3
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    • pp.227-234
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    • 1991
  • This study deals with concentration and light extinction of atmospheric aerosol in Seoul. From the measured aerosol size distribution for particle diameter ranging from 0.01 $\mum \sim 1.0 \mum$, extinction coefficient is calculated using the Mie theory. The results show that the diurnal variation of aerosol concentration, in general, reveals the lowest concentration in early morning and afternoon, while the highest at about 8 O'clock owing to the heavy traffic and accumulation of air pollution in the low atmosphere. However, aerosol concentration and extinction coefficient on April 7 give low values due to the advective wind. On the other hand, high aerosol concentration and extinction coefficenat are recorded on April 10 although solar radiation is weak. From the distribution of extinction coefficient we can find that aerosol particles of 0.1 $\mum \sim 1.0 \mum$ in diameter are highly effective on light extinction.

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Evaluation of BCL-6, CD10, CD138 and MUM-1 Expression in Diffuse Large B-Cell Lymphoma patients: CD138 is a Marker of Poor Prognosis

  • Bodoor, Khaldon;Matalka, Ismail;Hayajneh, Rami;Haddad, Yazan;Gharaibeh, Waleed
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.7
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    • pp.3037-3046
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    • 2012
  • The diffuse large B-cell lymphoma (DLBCL) encompasses two major groups of tumors with uneven survival outcomes - germinal center B-cell (GCB) and non-germinal center B-cell (non-GCB). In the present study, we investigated the expression of GCB markers (BCL-6 and CD10) and non-GCB markers (CD138 and MUM-1) in an effort to evaluate their prognostic value. Paraffin-embedded tumor biopsies of 46 Jordanian DLBCL patients were analyzed, retrospectively, by immunohistochemistry to investigate the expression of BCL-6, CD10, CD138 and MUM-1. In addition, survival curves were calculated with reference to marker expression, age, sex and nodal involvement. Positive expression of BCL-6, CD10, CD138 and MUM-1 was shown in 78%, 61%, 39% and 91% of the cases, respectively, that of BCL-6 being associated with better overall survival (p = 0.02), whereas positive CD138 was linked with poor overall survival (p = 0.01). The expression of CD10 and MUM-1 had no impact on the overall survival. Among the clinical characteristics studied, diagnosis at an early age, nodal involvement and maleness were associated with a higher overall survival for DLBCL patients. Our results underline the importance of BCL-6 as a marker of better prognosis and CD138 as a marker of poor prognosis for DLBCL patients.

The Social Effects of Higher Education Policy in South Korea: The Rise of the "Pig Mum" phenomenon

  • Lee, Eugene;Calonge, David Santandreu;Hultberg, Patrik
    • Journal of Contemporary Eastern Asia
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    • v.18 no.1
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    • pp.70-93
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    • 2019
  • The contemporary educational system in South Korea is built on high-stakes standardised tests, a manifestation of the national project of social reconstruction and reform. One recent outcome is the emergence of an unfamiliar yet ubiquitous phenomenon: the "pig mum"; a Korean parent who is fully involved in organising, scheduling and managing the educational process from primary to secondary school for a group of children in a neighbourhood. Based on a quasimixed method utilizing a survey of a group of students and parents, this pilot study explores the "pig mum" phenomenon and its linkage to education policy. The authors conclude that the current educational policy fails to achieve the ideals it professes to value. This creates deep and negative societal norms that endanger a growing generation of students by creating a parallel private education market environment where "pig mums" thrive.

A Study on the Characteristics of Urban Aerosol Concentration in the Size Range of 0.01~$1.0\mu\textrm{m}$ (도시 대기 Aerosol의 입자직경 0.01~$1.0\mu\textrm{m}$ 범위의 농도변화 특성)

  • 김필수;김윤장;이양호;조숙현;안승태
    • Journal of Korean Society for Atmospheric Environment
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    • v.2 no.2
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    • pp.41-50
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    • 1986
  • Urban aerosol concentrations in the size range of $0.01 \sim 1.0 \mum$ have been measured by using an electrical aerosol analyzer from May through October, 1984. The total diurnal variation of the number concentration indicates that a minimum value is observed at 3 hr and a sharp increase is noticed early in the morning with a subsequent slow and continuous increase from around 7 hr until 20 hr. After that it is decreased to reach its minimum by dawn. However, both surface and volume concentrations have shown that their first maxima at 8 hr and their second at about 20 hr simultaneously. It is found that the aerosol number is mainly governed by the particles in the size range of $0.01 \sim 0.1 \mum$, while most volume is in $0.1 \sim 1.0 \mum$ size range. It is known fact that particles of $0.1 \sim 1.0 \mum$ size range affect the visibility reduction in the atmosphere. The monthly variation of aerosol concentration remarks its minimum in summer. The main factors influencing the aerosol concentration are emission of autoexhausts, various processes of production and removal, and meteorological parameters.

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