• Journal of Environmental Health Sciences
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• v.42 no.1
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• pp.1-9
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• 2016

Objectives: Personal exposure to air pollution is affected by contact over time and by location. The purpose of this study was to determine the relationship between personal exposure to $PM_{2.5}$ and the time-activity patterns of the elderly in urban and rural areas. Methods: A total of 44 elderly participants were recruited for a 24-hour $PM_{2.5}$ personal exposure measurement. Twenty-four were from Seoul (urban area) and 20 were from Asan (rural area). Energy expenditure and spatiotemporal positioning were monitored through $PM_{2.5}$ measurement. Spearman correlation analysis was conducted to determine the relationship between $PM_{2.5}$ and time-activity pattern. Results: Daily average $PM_{2.5}$ personal exposures were $19.1{\pm}9.7{\mu}g/m^3$ in Seoul and $29.1{\pm}16.9{\mu}g/m^3$ in Asan. Although outdoor exposure was higher in Seoul than in Asan, residential indoor exposure was higher in Asan than in Seoul. Higher $PM_{2.5}$ personal exposure in Asan could be explained by longer time in residential indoor environments and higher indoor $PM_{2.5}$ concentrations. Seoul elderly had higher energy expenditure, which may be due to the use of mass transportation. Conclusion: Personal exposure to $PM_{2.5}$ was higher among Asan elderly than Seoul elderly because of high residential indoor concentrations and longer residential time. Lack of energy spent and higher personal exposure to $PM_{2.5}$ might have led to higher risk among the Asan elderly.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.8 no.1
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• pp.170-178
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• 2004

In this work a high speed 8-error correcting Reed-Solomon decoder is designed using the modified Euclid algorithm. Decoding algorithm of Reed-Solomon codes consists of four steps, those are, compute syndromes, find error-location polynomials, decide error-locations, and determine error values. The decoding speed is increased and the latency is reduced by using the parallel architecture in the syndrome generator and a faster clock speed in the modified Euclid algorithm block. In addition. the error locator polynomial in Chien search block is separated into even and odd terms to increase the overall speed of the decoder. All the functionalities of the decoder are verified first through C++ programs. Verilog is used for hardware description, and then the decoder is synthesized with a $.25{\mu}m$ CMOS TML library. The functionalities of the chip is also verified through test vectors. The clock speed of the chip is 250MHz, and the maximum data rate is 1Gbps.

• Korean Journal of Pharmacognosy
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• v.26 no.2
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• pp.116-121
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• 1995

To seek for a stable supply source of taxol as an anticancer agent urgently needed for the treatment of ovarian cancer, the concentrations of taxol and cephalomannine in bark and needles of 37 yew (Taxus cuspidata S. et Z.) trees grown in 6 locations of Cheju Island were analyzed by using HPLC. A considerable variation in the content was observed in plant part and the location. The average taxol content in the needles ($220.3{\;}{\pm}{\;}56{\;}{\mu}g$ per g dry wt) was ca. 4 times hgher than that in the bark, whereas the content of cephalomannine in the needles $(353{\;}{\pm}{\;}141{\;}{\mu}g)$ was ca. 5 times higher than that in the bark. Particularly, even within Cheju Island, needles from trees grown near the coast including Sogwipo area contained much higher taxol contents than needles from trees grown at mountain locations, indicating that taxane level is affected by environmental effects. Taxol in the needles was confirmed by electrospray mass spectrometry. These results suggest that the needles of yew trees growing in Cheju Island may provide a renewable source for taxol.

• Journal of Internet Computing and Services
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• v.11 no.4
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• pp.23-32
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• 2010

In this paper, we first propose the security enhancing of authentication protocol for Hash based RFID tag, and then a digital Codec for RFID tag is designed based on the proposed authentication protocol. The protocol is based on a three-way challenge response authentication protocol between the tags and a back-end server. In order to realize a secure cryptographic authentication mechanism, we modify three types of the protocol packets which defined in the ISO/IEC 18000-3 standard. Thus active attacks such as the Man-in-the-middle and Replay attacks can be easily protected. In order to verify effectiveness of the proposed protocol, a digital Codec for RFID tag is designed using Verilog HDL, and also synthesized using Synopsys Design Compiler with Hynix $0.25\;{\mu}m$ standard-cell library. Through security analysis and comparison result, we will show that the proposed scheme has better performance in user data confidentiality, tag anonymity, Man-in-the-middle attack prevention, replay attack, forgery resistance and location tracking.

• Korean Journal of Optics and Photonics
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• v.13 no.6
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• pp.521-529
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• 2002

We have recently proposed the new concept of a phase-measuring volumetric interferometer that enables us to accurately measure the xyz-coordinates of the probe without metrology frames. The interferometer is composed of a movable target and a fixed photo-detector array. The target is made of point diffraction sources to emit two spherical wavefronts, whose interference is monitored by an array of photo-detectors. Phase shifting is applied to obtain the precise phase values of the photo-detectors. Then the measured phases are fitted to a geometric model of multilateration so as to determine the xyz-location of the target by minimizing least square errors. The proposed interferometer has been designed and built with a volumetric uncertainty of less than 1.0 $\mu\textrm{m}$ within a cubic working volume of side 120 mm. Here, in this paper, we also present error sources, an evaluated uncertainty, and test results from the prototype system. The self-calibration of two-dimensional precision metrology stages is applied to test the performance of the interferometer.

• Journal of Biomedical Engineering Research
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• v.17 no.4
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• pp.449-458
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• 1996

Most of the conventional electrocardiowaphs foil to detect signals other than P-QRS-T due to the limited SNR and bandwidth. High-resolution electrocardiography(HRECG) provides better SNR and wider bandwidth for the detection of micro-potentials with higher frequency components such as vontricular late potentials(LP). We have developed a HRECG using uncorrected XYZ lead for the detection of LPs. The overall gain of the amplifier is 4000 and the bandwidth is 0.5-300Hz without using 60Hz notch filter. Three 16-bit A/D converters sample X, Y, and Z signals simultaneously with a sampling frequency of 2000Hz. Sampled data are transmitted to a PC via a DMA-controlled, optically-coupled serial communication channel. In order to further reduce the noise, we implemented a signal averaging algorithm that averaged many instances of aligned beats. The beat alignment was carried out through the use of a template matching technique that finds a location maximizing cross-correlation with a given beat tem- plate. Beat alignment error was reduced to $\pm$0.25ms. FIR high-pass filter with cut-off frequency of 40Hz was applied to remove the low frequency components of the averaged X, Y, and Z signals. QRS onset and end point were determined from the vector magnitude of the sigrlaIL and some parameters needed to detect the existence of LP were estimated. The entire system was designed for the easy application of the future research topics including the optimal lead system, filter design, new parameter extraction, etc. In the developed HRECG, without signal averaging, the noise level was less than 5$\mu$V$_rms RTI$. With signal averaging of at least 100 beats, the noise level was reduced to 0.5$\mu$V$_rms RTI$, which is low enough to detect LPs. The developed HRECG will provide a new advanced functionality to interpretive ECG analyzers.

• The Korean Journal of Nuclear Medicine Technology
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• v.14 no.1
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• pp.78-82
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• 2010

Purpose: Recently, South Korea has seen a rapidly increased incidence of both breast and thyroid cancers. As a result, the I-131 scan and lymphoscintigraphy have been performed more frequently. Although this type of diagnostic imaging is prominent in that visualizes pathological conditions, which is similar to previous nuclear diagnostic imaging techniques, there is not much anatomical information obtained. Accordingly, it has been used in different ways to help find anatomical locations by transmission scan, however the results were unsatisfactory. Therefore, this study aims to realize an imaging technique which shows more anatomical information through the fusion of gamma and realistic imaging. Materials and Methods: We analyzed the data from patients who were examined by the lymphoscintigraphy and I-131 additional scan by Symbia Gamma camera (SIEMENS) in the nuclear medicine department of the National Cancer Center from April to July of 2009. First, we scanned the same location in patients by using a miniature camera (R-2000) in hyVISION. Afterwards, we scanned by gamma camera. The data we obtained was evaluated based on the scanning that measures an agreement of gamma and realistic imaging by the Gamma Ray Tool fusion program. Results: The amount of radiation technicians and patients were exposed was generated during the production process of flood source and applied transmission scan. During this time, the radiation exposure dose of technicians was an average of 14.1743 ${\mu}Sv$, while the radiation exposure dose of patients averaged 0.9037 ${\mu}Sv$. We also confirmed this to matching gamma and realistic markers in fusion imaging. Conclusion: Therefore, we found that we could provide imaging with more anatomical information to clinical doctors by fusion of system of gamma and realistic imaging. This has allowed us to perform an easier method in which to reduce the work process. In addition, we found that the radiation exposure can be reduced from the flood source. Eventually, we hope that this will be applicable in other nuclear medicine studies. Therefore, in order to respect the privacy of patients, this procedure will be performed only after the patient has agreed to the procedure after being given a detailed explanation about the process itself and its advantages.

• The Journal of Korean Society for Radiation Therapy
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• v.29 no.1
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• pp.57-68
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• 2017

Purpose: The purpose of this study was to compare volumetric modulated arc therapy(VMAT) with fixed-field intensity modulated radiation therapy(IMRT) using non-coplanar beam when the shape of target is irregular and the location is adjacent to organ at risk(OAR). Materials and Methods: The subjects of this study were a total of 6 patients who had radiation therapy for whole scalp(2 patients), partial scalp(2 patients), and whole ventricle(2 patients) by True Beam STX(Varian Medical Systems, USA). VMAT plans consisted of coplanar or non-coplanar arcs which can minimize the volume of OAR included in beamlets. All fixed-field IMRT plans consisted of non-coplanar beams using more than 2 angles of Couch. Results: The VMAT and IMRT plans were compared with regard to the maximum dose of both lens, both optic nerves, optic chiasm, and brain stem and the mean dose of both eyeballs and hippocampus. VMAT plans showed higher dose than ncIMRT plans at more than 6 of all OARs in every patient, and the ratio was from 1.1 times to 8.2 times. In case of total scalp and partial scalp, the volume of brain which received more than 20 Gy in the VMAT plans was 2 times larger than the volume in the ncIMRT plans. In case of whole ventricle, there was no significant difference. Target coverage was satisfied in both plans($PTV_{100%}=95%$). The maximum dose in target volume and required monitor unit(MU) of ncIMRT were higher than them of VMAT plans. Conclusion: Even though ncIMRT is less efficient than VMAT with regard to required MU and treatment time, the dose to OARs is much lower than VMAT and PTV Coverage is similar with VMAT. If the shape of target is irregular and location is adjacent to OAR, comparison VMAT plan with ncIMRT plan deserves to be considered.

• The Journal of Korean Society for Radiation Therapy
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• v.25 no.1
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• pp.9-14
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• 2013

Purpose: High-energy radiotherapy with 10 MV or higher develops photoneutron through photonuclear reaction. Photoneutron has higher radiation weighting factor than X-ray, thus low dose can greatly affect the human body. An accurate dosimetric calculation and consultation are needed. This study compared and analyzed the dose change of photoneutron in terms of space according to the size of photon beam energy and treatment methods. Materials and Methods: To measure the dose change of photoneutron by the size of photon beam energy, patients with the same therapy area were recruited and conventional plans with 10 MV and 15 MV were each made. To measure the difference between the two treatment methods, 10 MV conventional plan and 10 MV IMRT plan was made. A detector was placed at the point which was 100 cm away from the photon beam isocenter, which was placed in the center of $^3He$ proportional counter, and the photoneutron dose was measured. $^3He$ proportional counter was placed 50 cm longitudinally superior to and inferior to the couch with the central point as the standard to measure the dose change by position changes. A commercial program was used for dose change analysis. Results: The average integral dose by energy size was $220.27{\mu}Sv$ and $526.61{\mu}Sv$ in 10 MV and 15 MV conventional RT, respectively. The average dose increased 2.39 times in 15 MV conventional RT. The average photoneutron integral dose in conventional RT and IMRT with the same energy was $220.27{\mu}Sv$ and $308.27{\mu}Sv$ each; the dose in IMRT increased 1.40 times. The average photoneutron integral dose by measurement location resulted significantly higher in point 2 than 3 in conventional RT, 7.1% higher in 10 MV, and 3.0% higher in 15 MV. Conclusion: When high energy radiotherapy, it should consider energy selection, treatment method and patient position to reduce unnecessary dose by photoneutron. Also, the dose data of photoneutron needs to be systematized to find methods to apply computerization programs. This is considered to decrease secondary cancer probabilities and side effects due to radiation therapy and to minimize unnecessary dose for the patients.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.38C no.3
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• pp.318-326
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• 2013

In this paper, a novel WUSB (Wireless USB) over WBAN (Wireless Body Area Networks) MAC protocol is proposed to improve efficiency of sensing the personal information. Furthermore, a localization technique based on that protocol is also proposed for indoor localization in a ship. For this purpose, the proposed localization algorithm minimizes power consumption and estimates location with accuracy. It is executed independently at each sensor node on the basis of WUSB over WBAN protocol. And it minimizes power consumption by estimating locations of sensor nodes without GPS (Global Positioning Systems).