• Women's Health Nursing
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• v.29 no.1
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• pp.66-75
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• 2023

Purpose: Supportive interventions to improve breastfeeding practice are needed in nursing. This study investigated the effects of pectoralis major myofascial release massage (MRM) on breast pain and engorgement among breastfeeding mothers and on breast milk intake and sleep patterns among newborns. Methods: Breastfeeding mothers who had delivered between 37 and 43 weeks and had 7-to 14-day-old newborns were recruited from a postpartum care center in Gunpo, Korea. Participants were randomized to the MRM or control group. The outcome variables were breast pain and breast engorgement among breastfeeding mothers and breast milk intake and sleep time among newborns. The experimental treatment involved applying MRM to separate the pectoralis major muscle and the underlying breast tissue in the chest. After delivery, the first MRM session (MRM I) was provided by a breast specialist nurse, and the second (MRM II) was administered 48 hours after MRM I. Results: Following MRM, breast pain (MRM I: t=-5.38, p<.001; MRM II: t=-10.05, p<.001), breast engorgement (MRM I: right, t=-1.68, p =.100; left, t=-2.13, p=.037 and MRM II: right, t=-4.50, p<.001; left, t=-3.74, p<.001), and newborn breast milk intake (MRM I: t=3.10, p=.003; MRM II: t=3.09, p=.003) differed significantly between the groups. Conclusion: MRM effectively reduced breast engorgement and breast pain in breastfeeding mothers, reducing the need for formula supplementation, and increasing newborns' breast milk intake. Therefore, MRM can be utilized as an effective nursing intervention to alleviate discomfort during breastfeeding and to improve the rate of breastfeeding practice (clinical trial number: KCT0002436).

• Journal of the military operations research society of Korea
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• v.31 no.1
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• pp.42-57
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• 2005

Korea DM&S(Defence Modeling & Simulation) development plan includes construction of a distributed simulation model which enables us to construct, operate, integrate and connect war game simulations. US DoD and IEEE set the HLA/RTI as the standard of distributed simulation model. HLA/RTI models each simulator as a Federate and group of them as a Federation. Simulation with the model shows interoperability and finally executes a war game simulation. Because of different resolutions and features, it is not satisfied 'interoperability' and 'reusability' of simulation perfectly MRM (Multi Resolution Modeling) has been introduced, and many developed countries including the United States have studied the technology to simulate the model with different resolutions. This thesis proposes the need for introduction of MRM and analyzes both technical and operational validity when we apply MRM model to army war game simulations. For these purposes, we 1) find MRM main issues with the study about MRM basic concepts and case studies of MRM's applications, 2) present the need of MRM and its relation with DM&S development plan, and 3) analyze its technical and operational validity when we apply MRM to an example, CHANG-JO21 and JEON-TOO21.

• Journal of Distribution Science
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• v.7 no.1
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• pp.91-104
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• 2009

The Purpose of this study is to reveal interactive relation between Product Life Cycle and Market Risk Management. PLC analyzes consumer buying behavior, volatility of price and sales at market place from the viewpoint of Marketing so that company can improve management result. This study is attempt to analyze PLC from a comprehensive and integrating angle by using MRM. In order to find out relationship between two theories, this study is an extraction of the factors that affects the management result commonly on PLC and MRM. Then, this study analyzes the factors of PLC from the viewpoint of MRM. The result shows that the factors of PLC and MRM have relation with in terms of volatility of price, trade risk and market share.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.1
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• pp.149-152
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• 2013

Objective: To compare the influence of breast-conserving surgery (BCS) and modified radical mastectomy (MRM) on the psychological state of breast cancer patients. Methods: Patients receiving MRM or BCS, and fulfilling the study criteria, were recruited. Patients were required to complete a self-reporting inventory (SCL-90) on admission and 6 months after surgery and a self-rating depression scale (SDS) when discharged from hospital and 6 months after surgery. Results: A total of 70 patients received MRM and 50 BCS. Compared with the national standard, patients suffered to some extent psychological problems on admission, at discharge from hospital and at 6 months after surgery. Patients received BCS had a higher score of SDS compared with those with MRM when discharged from hospital. However, 6 months after surgery, SDS score increased in MRM and decreased in the BCS group, so the difference was significant. Conclusion: The short-term psychological state of patients receiving BCS is worse than that with MRM but superior to MRM 6 months postoperatively. BCS imposed less influence on long term psychological state of breast cancer patients compared with MRM.

• Journal of the Korea Institute of Military Science and Technology
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• v.23 no.4
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• pp.417-425
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• 2020

Multi-resolution modeling(MRM) is required when simulating objects in variable resolution and can be applied for interoperating systems, which simulate objects in fixed resolution. However, most interoperation middleware do not support MRM, so participating models must handle several issues to simulate MRM system. In this paper, we propose an interoperation system, which is composed of several different resolution models, based on the High Level Architecture and Run-Time Infrastructure(HLA/RTI). In the proposed architecture, each model participates to a HLA federation through MRM adapter application, which supports data resolution conversion and HLA services while communicating with the model. MRM adapter application can be implemented based on an MRM adapter, and an adapter application development tool is proposed to support developing the application. Using the tool, developers can easily implement data resolution conversion component plugged-in HLA adapter. A case study is implemented in the proposed MRM system, and shows that models of different resolution works successfully with dynamic resolution changes.

• Mass Spectrometry Letters
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• v.1 no.1
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• pp.21-24
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• 2010

The development of clinical biomarkers involves discovery, verification, and validation. Recently, multiple reaction monitoring (MRM) coupled with stable isotope dilution mass spectrometry (IDMS) has shown considerable promise for the direct quantification of proteins in clinical samples. In particular, multiple biomarkers have been tracked in a single experiment using MRM-based MS approaches combined with liquid chromatography. We report here a highly reproducible, quantitative, and dynamic MRM system for validating multi-biomarker proteins using Nanoflow HPLC-Microfluidics Chip/Triple-Quadrupole MS. In this system, transitions were acquired only during the retention window of each eluting peptide. Transitions with the highest MRM-MS intensities for the five target peptides from colon cancer biomarker candidates were automatically selected using Optimizer software. Relative to the corresponding non-dynamic system, the dynamic MRM provided significantly improved coefficients of variation in experiments with large numbers of transitions. Linear responses were obtained with concentrations ranging from fmol to pmol for five target peptides.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.20 no.1
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• pp.174-192
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• 2021

The LIDAR sensor, which provides higher cognitive performance than cameras and radar, is difficult to apply to ADAS or autonomous driving because of its high price. On the other hand, as the price is decreasing rapidly, expectations are rising to improve existing autonomous driving functions by taking advantage of the LIDAR sensor. In level 3 autonomous vehicles, when a dangerous situation in the cognitive module occurs due to a sensor defect or sensor limit, the driver must take control of the vehicle for manual driving. If the driver does not respond to the request, the system must automatically kick in and implement a minimum risk maneuver to maintain the risk within a tolerable level. In this study, based on this background, a LIDAR-based LKS MRM algorithm was developed for the case when the normal operation of LKS was not possible due to troubles in the cognitive system. From point cloud data collected by LIDAR, the algorithm generates the trajectory of the vehicle in front through object clustering and converts it to the target waypoints of its own. Hence, if the camera-based LKS is not operating normally, LIDAR-based path tracking control is performed as MRM. The HAZOP method was used to identify the risk sources in the LKS cognitive systems. B, and based on this, test scenarios were derived and used in the validation process by simulation. The simulation results indicated that the LIDAR-based LKS MRM algorithm of this study prevents lane departure in dangerous situations caused by various problems or difficulties in the LKS cognitive systems and could prevent possible traffic accidents.

• Journal of Korean Neurosurgical Society
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• v.52 no.2
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• pp.103-106
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• 2012

Objective : To prospectively assess the diagnostic and clinical value of a new technique (3-tesla magnetic resonance myelography, 3T MRM) as compared to computed tomographic discography (disco-CT) in patients with far lateral disc herniation. Methods : We evaluated 3T MRM and disco-CT of 25 patients, whom we suspected of suffering from far lateral disc herniation. Using an assessment scale, 4 observers examined independently both 3T MRM and disco-CT images. We analyzed observer agreement and the accentuation of each image. Results : We found complete matching, and observer agreement, between high resolution images of 3T MRM and disco-CT for diagnosing far lateral disc herniation. Conclusion : We think noninvasive 3T MRM is an appropriate diagnostic tool for far lateral disc herniation as compared to disco-CT.

• Mass Spectrometry Letters
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• v.14 no.2
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• pp.36-41
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• 2023

A simple method was developed to determine residual p-arsanilic acid (ASA), an organo-arsenic compound used as a feed additive, in aquatic products (eel, halibut, and shrimp) using EDTA-assisted solvent extraction and LC-MRM. The method was successfully validated in terms of specificity, linearity (coefficient of determination ≥ 0.995), accuracy (recovery or R, 72.72-78.73%), precision (the relative standard deviation of R, 2.08-6.98%), and sensitivity (the lower limit of quantitation, 5 ppb) according to CODEX guidelines (CAC-GL 71-2009). The use of EDTA in the extraction solvent and water with a suitable pH modifier as the reconstitution solvent may be the key factors for successful results. This is the first method that can be used for monitoring residual ASA in aquatic products using LC-MRM and could contribute to establishing a better aquatic product safety management system.

• Korean Journal of Environmental Agriculture
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• v.23 no.3
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• pp.158-169
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• 2004

For the improvement of gas chromatographic analysis of multiple pesticide residues in green pepper, lettuce and Chinese cabbage, multiresidue test mixtures (MRTMs) of 10 groups (ECD 5 groups and NPD 5 groups) and a recovery test mixture (RTM) of 18 compounds (11 compounds for ECD and 7 compounds for NPD) were established based on retention time and response to relevant detectors. A new extraction solvent (acetone: acetonitrile=1 : 9) and a clean up eluent (hexane: dichloromethane : acetonitile = 50 : 48.5 : 1.5) for solid-phase extraction (SPE) cartridge were selected to test two types of multiresidue methods (MRM I and MRM II). MRM II provided high recovery better than MRM I when RTM was tested Recovery experiment with MRTMs which was conducted using MRM II resulted in that more than seventy percents of compounds were recovered in the range of $50{\sim}140%$, while 9% of compounds were over 140% of recovery and only $7{\sim}8$ compounds failed to detect. MRM II, an improved method, could be employed for screening residues of 190 pesticides in those vegetables.