• 제목/요약/키워드: MP119

검색결과 11건 처리시간 0.03초

식물추출복합발효물(MP119)이 성기능에 미치는 영향 및 카드뮴 독성에 대한 효과 (Effect of Phyto-Extract Fermented Mixture (MP119) on the Sexual Functions and on the Toxicities of Cadmium)

  • 장영선;정종문
    • 한국식품영양과학회지
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    • 제38권12호
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    • pp.1724-1731
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    • 2009
  • 마카, 홍삼, 남가새 추출물을 일정한 무게 비율로 혼합하여 발효시켜 얻어진 식물추출복합발효물(MP119)이 성기능에 미치는 영향을 조사하였다. ACE(angiotensin converting enzyme)과 PDE(phosphodiesterase)에 대한 저해효과를 통해 혈액순환부진 개선 및 cGMP 농도에 의한 발기능 개선에 미치는 효과를 측정하였다. MP119의 ACE 저해효과를 측정한 결과 $IC_{50}$값이 241.3${\pm}$35.5 ppm, PDE 저해효과를 측정한 결과 $IC_{50}$값이 372.2${\pm}$33.8 ppm으로 나타나 혈관확장으로 인한 혈류량 증가 및 cGMP농도 증가에 영향을 줄 수 있을 것으로 예상된다. MP119는 마우스 정소세포인 TM3 cell에 유의성 있는 독성이 나타나지 않았으며, TM3 cell에 농도별로 처리했을 때 세포배양액으로부터 대조군과 비교하여 최대 20.11% 증가한 testosterone 농도를 확인하였다. 또한 HUVEC에 농도별로 처리했을 때 NO생산량이 MP119 처리 농도가 증가할수록 유의성 있게 증가하였다. 웅성마우스에 MP119를 7일간 경구투여 후 생식장기의 무게와 정자수를 측정하고, MP119를 경구투여한 후 염화카드뮴을 투여하여 생식장기의 무게와 정자수를 측정하였다. 또한 실험쥐로부터 혈청을 분리하여 혈청 내 testosterone과 cGMP를 측정하였다. 그 결과 MP119의 투여를 통해 생식장기의 무게 변화 없이 정자수 증가에 도움을 준다는 것을 확인하였으며, 더불어 혈청 내 testosterone 및 cGMP의 농도 역시 증가하였다. MP119를 투여한 후 염화카드뮴을 투여한 실험군에서 역시 정자수 및 혈청 내 testosterone, cGMP 농도 증가를 나타내었으므로 결과적으로 MP119가 염화카드뮴의 독성예방 및 치료에 효과적임을 확인하였다.

수출마케팅에서 무역e-Marketplace 참여기업의 환경-활용-성과모형에 관한 연구 (Environment-Usage-Performance Model on Participating Firms of Electronic Marketplace in Export Marketing)

  • 정창근;곽수영
    • 통상정보연구
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    • 제9권1호
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    • pp.119-148
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    • 2007
  • The purpose of this research is to study whether environments of participating firms of electronic marketplace(e-MP) have an influence on usage factors which are supplying from e-MP and usage factors affect usage performances. Based on the existing researches we found variables and executed a empirical study of environment-usage-performance model. Through this research we suggested useful factors for the performance of trade enterprises. Usage factors of e-MP will overcome geographical limitation and acquire new sales areas and simultaneously widen the relationships of global enterprises. Those firms could be accessible into global market promptly. To enhance usages of e-MP, service quality which can satisfy both buyer and seller at the same time should be strengtened. Finally, the usage of e-trade information should also heighten through usage factors.

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Naturally Derived Probiotic Supplementation Effects on Physiological Properties and Manure Gas Emission of Broiler Chickens

  • Hassan, Md R.;Ryu, Kyeong-Sun
    • 농업생명과학연구
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    • 제46권4호
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    • pp.119-127
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    • 2012
  • To investigate the influence of multi-probiotic, fermented ginseng byproduct and fermented sulfone on the performance, intestinal microflora and immunity of broiler, a five weeks trial was conducted with 340, 1-d-old $Ross{\times}Ross$ broiler. All broilers were divided into five different groups having 68 birds in each treatment, and they were assigned as control, antibiotic avilamycin (AB), multi-probiotic (MP), fermented sulfone (FS) and fermented ginseng byproduct (FGB). Each artificial or naturally derived probiotic was inoculated 0.1% level with the basal diet, and all diets were provided to birds for five weeks. Weight gain and feed intake were measured weekly basis, and blood, spleen and feces were collectedand used for the physiological properties of broiler chickens. All performances and cholesterol profiles were not significantly differed but numerically lower level of neutral fat and LDL was found in multi-probiotics and FGB treatments respectively. The salmonella spp and E. coli numbers in the ileum were high in control in relation to those of other treatments and were significantly decreased in antibiotics treatments (p<0.05). In addition, Lactobacillus spp. showed significantly higher proliferation in MP as compared to that of others (p<0.05). Fecal ammonia and $CO_2$ gas emission was significantly decreased in MP, FGB and FS, respectively (p<0.05), but significantly increased proliferation of spleen was determined in MP group in comparison of other treatments (p<0.05). Therefore, the results indicates that multi-probiotics would be valuable feed additives to improve the salmonella, E. coli and Lactobacillus proliferation, and manure gas emission of broiler chickens, but further study related to the production of manure gas emission of MP is necessary.

Predictive model of fatigue crack detection in thick bridge steel structures with piezoelectric wafer active sensors

  • Gresil, M.;Yu, L.;Shen, Y.;Giurgiutiu, V.
    • Smart Structures and Systems
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    • 제12권2호
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    • pp.97-119
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    • 2013
  • This paper presents numerical and experimental results on the use of guided waves for structural health monitoring (SHM) of crack growth during a fatigue test in a thick steel plate used for civil engineering application. Numerical simulation, analytical modeling, and experimental tests are used to prove that piezoelectric wafer active sensor (PWAS) can perform active SHM using guided wave pitch-catch method and passive SHM using acoustic emission (AE). AE simulation was performed with the multi-physic FEM (MP-FEM) approach. The MP-FEM approach permits that the output variables to be expressed directly in electric terms while the two-ways electromechanical conversion is done internally in the MP-FEM formulation. The AE event was simulated as a pulse of defined duration and amplitude. The electrical signal measured at a PWAS receiver was simulated. Experimental tests were performed with PWAS transducers acting as passive receivers of AE signals. An AE source was simulated using 0.5-mm pencil lead breaks. The PWAS transducers were able to pick up AE signal with good strength. Subsequently, PWAS transducers and traditional AE transducer were applied to a 12.7-mm CT specimen subjected to accelerated fatigue testing. Active sensing in pitch catch mode on the CT specimen was applied between the PWAS transducers pairs. Damage indexes were calculated and correlated with actual crack growth. The paper finishes with conclusions and suggestions for further work.

RGP lens 다목적용액의 습윤성에 관한 비교 연구 (The Comparative Study on the wettability of the RGP lens multi-purpose solutions(MPSs))

  • 박현주;고은경;서은선;김재민;이기영
    • 한국안광학회지
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    • 제8권2호
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    • pp.119-127
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    • 2003
  • 지질이 소수성인 RGP lens의 관리용액인 다목적용액(multipurpose solution, MPS)에서 중요한 요소인 습윤성에 대해 알아보고자 시중에 유통 중인 6개사 제품을 측정 비교해 보았다. 실험에 사용한 MPS는 ALCON의 OPTI-SOAK, CIBA Vision의 SOLO care hard, ALLEKGAN의 Total care, BOSTON의 Simplicity, B&L의 Wetting and Soaking Sol., 그리고 Saehan의 Aquas-multi였으며, 실험방법은 각각에 대해 접촉각과 표면장력, 점도를 측정하였다. 결과는 RGP lens를 8시간 MPS에 담근 후 인공누액을 떨어뜨려 측정한 접촉각은 $25^{\circ}{\sim}36^{\circ}$의 범위로 렌즈와 MPS는 비교적 우수한 습윤성을 보여주었으며, 표면장력은 19.8~31.3 mN/m의 값이 얻어졌다. 각각의 다목적용액에 렌즈를 홀더에 얹은 상태로 계면과 렌즈가 분리될 때의 표면장력을 측정하였을 때는 26.5~33.5mN/m의 값이 측정되었다. 점도는 $4^{\circ}C$$28^{\circ}C$에서 측정했으며 측정온도에 따라 온도가 낮을수록 높게 측정되었고, MPS의 온도 $28^{\circ}C$에서 측정했으며 측정온도에 따라 온도가 낮을수록 높게 측정되었고, MPS의 온도 $28^{\circ}C$에서 점도는 9.5~65.5 cps를, $4^{\circ}C$에서는 6.5~137 cps의 값을 보였다. RGP lens MPS는 soft lens MPS에 비해 접촉각과 표면장력은 낮고, 점도는 높아서 습윤성이 더 우수하였는데 제조회사에 따라 습윤성의 차이가 다소 있었다.

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옥상녹화가 PV모듈 발전량에 미치는 영향 고찰 (A study on the effect that the green roof has on the performance of PV module)

  • 유동철;이응직
    • 한국태양에너지학회 논문집
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    • 제32권2호
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    • pp.113-119
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    • 2012
  • This study aims to examine the effect of the combined application of green roof and PV system on the PV efficiency by measuring the temperature and performance of PV module in order to reduce the temperature on the roof using roof planting system and determine the potential of efficient increase in solar-light power generation. In the experimental methodology, either monocrystalline or polycrystalline PV module was installed in green roof or non-green roof, and then the surface temperature of PV was measured by TR-71U thermometer and again the performance, module body temperature, and conversion efficiency were measured by MP-160, TC selector MI-540, and PV selector MI-520, respectively. As a result, the average body temperature of monocrystalline module was lower by $6.5^{\circ}C$ in green roof than in non-green roof; that of polycrystalline module was lower by $8.8^{\circ}C$ in green roof than in non-green roof. In the difference of generation, the electricity generation of monocrystalline module in green roof was 46.13W, but that of polycrystalline module was 68.82 W, which indicated that the latter produced 22.69W more than the former.

종합병원근무 신규 간호사의 이직경험에 관한 현상학적 연구 (A Phenomenological Study on the Turnover Experience of Novice Nurses Working in General Hospital)

  • 임보미;박종민;김미진;김수연;맹정호;이루리;강경아
    • 한국직업건강간호학회지
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    • 제24권4호
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    • pp.313-322
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    • 2015
  • Purpose: The purpose of this study was to identify novice nurses' experience of turnover. Methods: Data were collected from June to August, 2014 through in-depth interview and E-mail. Twelve novice nurses with turnover experiences were selected through snowball sampling method. All interviews were recorded with MP3 recorder and transcribed for analyzing by Van Kaam method of phenomenology. Results: The results were divided into 4 categories, 20 themes, and 119 formulated meaning related to turnover experience. These four categories were 'Excessively heavy working environment', 'Relationship problem', 'Physical/emotional withdrawal', and 'Realizing the absence of goal in job'. Conclusion: The result of this study will offer anticipatory information to understand of novice nurses' difficulties and to prevent their turnover. And these findings can be used for nursing administrators to design a turnover prevention program more effectively for nurses.

미생물에 의한 5′-이노신산의 생산에 관한 연구 (제1보) 5′-이노신산 생산균주의 분리 (Studies on the Fermentative Production of Inosine-5′-monophosphate by Microorganisms (Part 1) Derivation of 5′-IMP Producing Mutants from Brevibacterium ammoniagenes)

  • 배종찬;공운영;손충홍;장욱;유주현
    • 한국미생물·생명공학회지
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    • 제7권3호
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    • pp.119-125
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    • 1979
  • (l) 핵산관련물질 생산균주의 분리를 위한 변이 유기제와 최적 처리조건은 UV; 30 cm, 1 min, NTG; 200 $\mu\textrm{g}$/ml, 20min, DES; 0.32 %, 90 min, EMS; 5%, 60 min 이었으며 이때 변이솔는 각각 0.083 %, 0.67%, 1.1 %, 및 0.45%로 DES가 가장 양호하였다. (2) Purine 영양요구변이주 239 strain 중 5'-IMP 생산균주는 모두 6 strain이었으며 이중 adenine-guanine 동시요구주 D-2150이 4.8mg/ml로 가장 우수하였다. (3) D-21530 strain의 배양액에서 얻은 결정을 paper chromatogram의 Rf치, 자외선 및 적외선 흡수 spectum 비교, 가수분해에 의한 hypoxanthine 생성량 및 orcinol 반응에 의한 D-ribose의 생성량을 검토한 결과 5'-IMP로 동정되었다. 이 연구을 할때 협력하여 주신 제일제당주식회사 김홍집 상무, 그리고 핵산의 정량분석을 하여준 문화식 씨에게 감사드립니다.

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유우의 산유능력 검정성적과 MUN 농도와의 비교분석 (Relationships between Milk Urea Nitrogen Concentration and Milk Components for Herd Management and Control in Gyeong-nam Dairy Cows)

  • 유용상;강동준;김철호;김태융;강정부
    • 한국임상수의학회지
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    • 제24권2호
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    • pp.119-124
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    • 2007
  • Milk components analysis was carried out milk yield(MY), milk fat(MF), milk protein(MP), milk urea nitrogen(MUN), milk solid(MS), day of non-pregnant condition(DNPC), and days of primipara(DPRI) involved. Dairy farms were divided high, middle and low groups according to the standard records for milk components. Examination records were divided by farm, parity, year, season and month, the number of samples were 28,957. MUN concentration was below 12 mg and when the MPP was below 3.0%, the days of non-pregnant condition were $94{\pm}10.77$ days but concentration of MUN was under 12 mg and when MPP was above 3.2%, longer period of non-pregnant condtion of $181.3{\pm}9.25$ was noted. The days of gestation of the first calving cow was $495.9{\pm}9.04$ days when the concentration of MUN was below 12mg/dl and MPP was under 3.0%. If the concentration of MUN was 12 mg/dl and when the MPP was over 3.2%, the days of gestation were $511.0{\pm}8.36$ days. It was believed that the concentrations of MPP and MUN have significant effects on the days of non-pregnant condition and the days of gestation. Determination of MY, MF, MS, and MUN was Milkoscan $4,000{\sim}5,000$ Serier(FOSS Electric Co., Copenhagen, Denmark). MUN standard concentration was 12-18(mg/dl) similar to blood urea nitrogen(BUN). Mutual relationship of milk components(MF, SCC, MY, DNPC, MS) and MUN concentration was low in regression analysis.

The Association Between Dietary Energy Density and Musculoskeletal Pain in Adult Men and Women

  • Niki Bahrampour;Niloufar Rasaei;Fatemeh Gholami;Cain C. T. Clark
    • Clinical Nutrition Research
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    • 제11권2호
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    • pp.110-119
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    • 2022
  • Musculoskeletal pains (MPs), defined as persistent or recurrent pain, is a complex health problem. High overall calorie and fat intake have been related to obesity and MPs. Dietary energy density (DED), defined as energy content of food and beverages (in kcal) per unit total weight, has been associated with chronic muscle, cartilage, bone damage and pain. Thus, the purpose of this study is to investigate the association between DED and MPs in adult men and women. A total of 175 men and women (> 18 years) with MP participated in the study. A validated short form physical activity (PA) questionnaire, demographic, and McGill Pain Questionnaire were used. Anthropometric measurements were evaluated via standard protocols. Furthermore, a seven-day 24-hour recall of diet was used to determine the dietary intake. Total DED was calculated and divided into quartiles. Linear regression was used to discern the association between DED and MPs in adults. Participants assigned in the highest category of DED were characterized by lower intake of potassium, magnesium, vitamin C, folate, and fiber. However, results showed displayed higher intake of sodium, vitamin E, vitamin B3, fat, protein, cholesterol, saturated fatty acids, monounsaturated fatty acids, and polyunsaturated fatty acids (p < 0.001). Finally, after adjustment for confounders such as age, gender, PA, body mass index, waist circumference, education, job, marital status, history of some chronic diseases and vitamin C supplementation, a significant positive association was detected between DED and pain intensity. There was no significant association between DED and pain frequency in all models.