• ETRI Journal
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• v.38 no.6
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• pp.1124-1134
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• 2016

The tone reservation method is one of the most effective pre-distortion methods for peak-to-average power ratio reduction in orthogonal frequency division multiplexing (OFDM) systems. Its direct application to OFDM systems with offset quadrature amplitude modulation (OQAM) is, however, not effective. In this paper, two novel TR-based methods are proposed, specifically designed for OFDM/OQAM systems by taking into consideration the overlapping nature of OQAM signals. These two methods have different approaches to the generation of the peak-cancelling signal. The first one (overlapped scaling tone reservation) generates the peak-cancelling signal using a least squares approximation algorithm with possible adjacent symbol overlap; the second one (multi-kernel tone reservation) generates the peak-cancelling signal by using multiple impulse-like time domain kernels. It is shown by simulation that, when used in OFDM/OQAM systems, the proposed methods can provide better performance than the direct application of the existing controlled clipping tone reservation method, and even outperform the multi-block tone reservation method.

• BMB Reports
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• v.50 no.7
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• pp.355-360
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• 2017

Mutations in Ras GTPase are among the most common genetic alterations in human cancers. Despite extensive research investigating Ras proteins, their functions still remain a challenge over a long period of time. The currently available data suggests that solving the outstanding issues regarding Ras could lead to development of effective drugs that could have a significant impact on cancer treatment. Developing a better understanding of their biochemical properties or modes of action, along with improvements in their pharmacologic profiles, clinical design and scheduling will enable the development of more effective therapies.

• Biomolecules & Therapeutics
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• v.27 no.3
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• pp.254-264
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• 2019

Atherosclerosis is a widespread and chronic progressive arterial disease that has been regarded as one of the major causes of death worldwide. It is caused by the deposition of cholesterol, fats, and other substances in the tunica intima which leads to narrowing of the blood vessels, loss of elasticity, and arterial wall thickening, thus causing difficulty in blood flow. Natural products have been used as one of the most important strategies for the treatment and prevention of cardiovascular diseases for a long time. In recent decades, as interests in natural products including medicinal herbs have increased, many studies regarding natural compounds that are effective against atherosclerosis have been conducted. The purpose of this review is to provide a brief overview of the natural compounds that have been used for the treatment and prevention of atherosclerosis, and their mechanisms of action based on recent research.

• Animal Bioscience
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• v.36 no.5
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• pp.692-703
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• 2023

Objective: The main goals of this investigation were to i) assess the population structure and genetic diversity and ii) determine the efficiency of the ongoing breeding program in a closed flock of Angora rabbits through pedigree analysis. Methods: The pedigree records of 6,145 animals, born between 1996 to 2020 at NTRS, ICAR-CSWRI, Garsa were analyzed using ENDOG version 4.8 software package. The genealogical information, genetic conservation index and parameters based on gene origin probabilities were estimated. Results: Analysis revealed that, 99.09% of the kits had both parents recorded in the whole dataset. The completeness levels for the whole pedigree were 99.12%, 97.12%, 90.66%, 82.49%, and 74.11% for the 1st, 2nd, 3rd, 4th, and 5th generations, respectively, reflecting well-maintained pedigree records. The maximum inbreeding, average inbreeding and relatedness were 36.96%, 8.07%, and 15.82%, respectively. The mean maximum, mean equivalent and mean completed generations were 10.28, 7.91, and 5.51 with 0.85%, 1.19%, and 1.85% increase in inbreeding, respectively. The effective population size estimated from maximum, equivalent and complete generations were 58.50, 27.05, and 42.08, respectively. Only 1.51% of total mating was highly inbred. The effective population size computed via the individual increase in inbreeding was 42.83. The effective numbers of founders (f_e), ancestors (f_a), founder genomes (f_g) and non-founder genomes (f_ng) were 18, 16, 6.22, and 9.50, respectively. The fe/fa ratio was 1.12, indicating occasional bottlenecks had occurred in the population. The six most influential ancestors explained 50% of genes contributed to the gene pool. The average generation interval was 1.51 years and was longer for the sire-offspring pathway. The population lost 8% genetic diversity over time, however, considerable genetic variability still existed in the closed Angora population. Conclusion: This study provides important and practical insights to manage and maintain the genetic variability within the individual flock and the entire population.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.8
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• pp.4461-4484
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• 2013

Cancer registration provides a firm basis for cancer control efforts and research into changing patterns of incidence, mortality, survival and prevalence is of obvious importance. Most of the countries of Asia have already published relevant data although the level of coverage and accuracy do vary a great deal both between and within countries. The present review concerns the relevant literature for the period 2008-2013, focusing on the types of research conducted and the conclusions that can be drawn with regard to what should be done in the future to translate the information available into effective intervention efforts to reduce the burden of disease. A major emphasis has been on determining variation in incidence and mortality/survival on the basis of ethnicity and socioeconomic as well as geographical background, as well as trends over time, either for cancer in general or specific organ sites. In addition a small number of papers focused on methodological, quality and cancer control issues, very pertinent to the future development of cancer registry based research.

• Journal of Acupuncture Research
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• v.17 no.4
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• pp.188-199
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• 2000

In the treatment of hemifacial spasm, the operative methods, such as neurovascular decompression, rhizotomy etc. are the most efficacious therapy on its control. But, due to some side effects and complication, pharmacotherapy has been the first attempted by first intention of hemifacial spasm. The cabamazepine is the most commonly used agent, however it is often inefficacious in some cases, and attenuates as the time passes, engages in some symptoms, such as dizziness, nausea, vomiting, and causes an aplastic anemia, it has many deficiencies in becoming the first intention. Acupuncture is a simple, effective and conservative spasm control modality. It is so simple to use in hemifacial spasm. We had observed 5 cases of hemifacial spasm which were treated by acupuncture in our hospital recently. We reported these cases and reviewed related literatures briefly. The results of treatment are as follows : The average grade of spasm intensity classified by Scott's description was 3 before acu-therapy and it became 2 after the therapy. These results suggest that acupuncture and ear-acupuncture were effective as the first intention in healing hemifacial spasm.

• Journal of Korea Port Economic Association
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• v.17 no.1
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• pp.73-90
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• 2001

Logistics has become a key element in a shipping firm's overall strategy, now that the concept of logistics has expanded into one that is more comprehensive and integrated. furthermore, the global shipping market is the most competitive market in the world. In this environment, shipping firms are using Logistics Information Systems (LIS), which help them to save time and reduce costs. As such, LIS has become a critical part of Korea's attempts to develop Its national logistics system and industry. In this light, this study attempted to empirically determine the critical elements necessary for effective shipping LIS implementation and to then analyze how these elements are related to actual logistics performance within the shipping industry. The research results show that the sample firms considered the following factors to be most Important to an effective LIS: the support of top management; an efficient and well-structured communication channel; a solid strategic implementation plan; and a high level of information analysis internally. Other factors mentioned as being somewhat significant included MIS organization and human resources, MIS discipline and training, software development capabilities, MIS organizational alignment, database management systems information standardization, competitive advantage, financial support and government support The main problems with current shipping LIS include the expensive cost of systems, lack of standardized working processes, and weak organizational structures.

• Korean Journal of Veterinary Research
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• v.64 no.2
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• pp.12.1-12.6
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• 2024

The current study aimed to determine the effect of silver and chitosan nanoparticles of size 10 to 30 nm on the dead of lice in vitro and in vivo to determine the optimal time and concentration to combat chicken lice. One hundred local chickens Gallus gallus domesticus were collected from Al-Diwaniyah province and 6 species of local chicken lice were isolated: Menacanthus stramineus, Menacanthus pallidullus, Menacanthus cornutus, Goniodes gigas, Cuclotogaster heterographus and Bonomiella columbae. The results of treating lice with chitosan and silver nanoparticles at concentrations (40, 60, and 80 mg/mL) in vitro and at different periods (5, 10, 15, and 30 minutes) after treatment showed that chitosan and silver nanoparticles at a concentration of 80 mg/mL are the most effective in killing lice. The dead rate of lice reached 100% after 15 minutes of treatment with chitosan nanoparticles and 100% in the case of silver nanoparticles after 30 minutes. The results of spraying chitosan and silver nanoparticles on the body of chickens infected with lice experimentally, based on the relative therapeutic efficacy within 30 minutes, indicated that silver nanoparticles were the most effective in completely killing lice in the group treated with a concentration of 80 mg/kg after 30 minutes, where the percentage of therapeutic efficacy was 96.7%. This was followed by chitosan nanoparticles at a concentration of 80 mg/kg, and the percentage of therapeutic efficiency was 91.5%. Chitosan and silver nanocomposite have a promising effect in the elimination of lice infestation in chickens.

• Culinary science and hospitality research
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• v.14 no.4
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• pp.106-118
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• 2008

Even though the number of food courts increased in recent years, there were few studies about them. Considering the effects of a food court on the sales of a mall or other shopping spots, it was necessary to analyze what kind of attribute attracts customers. For this research, conjoint analysis was used to test which attribute was the most decisive factor, and the results of this study were as follows. First, price was the first factor that customers attached great importance to. Next were time required from order to eat and menu diversity. Second, cluster analysis used by the individual value of utilities derived through the conjoint analysis showed two clusters. Third, the most preferred food court form gained 35.4% potential market share from the simulation. The information gained from this analysis provided an important starting point for marketing and determined what kind of attribution was considered in being part of the malls or buildings. Also, it could be made full use of creating and executing the most effective marketing strategies.

• Journal of the Korean Society of Food Culture
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• v.17 no.5
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• pp.605-618
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• 2002

The purposes of this research were to; (a) identify useful information source; (b) assess the usefulness of the Internet as an information source; and (c) assess the degree of Internet utilization for purchasing process in food service industry. The results were as follows; 1. 'personal experience and colleague recommendation' was perceived as the most useful information source, whereas the most frequently used source was 'Internet web site' for real purchasing practice. 2. the most frequently used purchasing activity through Internet was 'online ordering', followed by 'gathering product/component information', however e-marketplace or Internet bidding were less performed by Internet. 3. acquisition of real time information, rapidity, accuracy, and increasing effectiveness of purchasing process were reported the advantages of Internet utilization. 4. respondents somewhat or strongly agreed with the importance of Internet in terms of present and future purchasing management. The results of the research suggest that Internet should be able to improve purchasing process and enhance buyer-supplier relationship directly or indirectly, therefore food service industry should consider making attempt to new purchasing systems through Internet for strategic sourcing and effective procurement management.