• Title/Summary/Keyword: MOP

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Screening of Inhibitors against Tyrosinase Activity from Natural Products (천연물로부터 티로시나제 활성 저해제의 검색)

  • 최상숙;노향순;조성희;공광훈
    • YAKHAK HOEJI
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    • v.45 no.5
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    • pp.522-528
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    • 2001
  • Tyrosinase plays an important role in the process of melanin biosynthesis, and it is a biochemical target enzyme for skin-whitening agents and the remedy for disturbances in pigmentation. We have screened 25 natural plant extracts for inhibitory effects against DOPA oxidase activity of tyrosinase. For the inhibitory effect against DOPA oxidase activity of tyrosinase, the recombinant human tyrosinase and the purified mushroom tyrosinase were used. Each of the dried plants extracted with methanol, and then the extracts were subjected to sequential fractionations with methylene chloride, ethyl acetate, n-butanol and water, respective The methylene chloride fractions of Angelica tenuissima, Nardostachys chinensis, Bombyx mop and Saposhnikovia divaricata, and the n-butanol fraction of Bombyx mori notably inhibited the human tyrosinase activity as well as mushroom tyrosinase activity (more than 90% inhibition). This study suggests that the above extracts have a potential as whitening agents as single ingredients or in combination with other of the extracts.

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Optimization of Multi-objective Function based on The Game Theory and Co-Evolutionary Algorithm (게임 이론과 공진화 알고리즘에 기반한 다목적 함수의 최적화)

  • 김지윤;이동욱;심귀보
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 2002.12a
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    • pp.395-398
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    • 2002
  • 본 논문에서는 ‘다목적 함수 최적화 문제(Multi-objective Optimization Problem MOP)’를 풀기 위하여 유전자 알고리즘을 진화적 게임 이론 적용시킨 ‘내쉬 유전자 알고리즘(Nash GA)’과 본 논문에서 새로이 제안하는 공진화 알고리즘의 구조를 설명하고 이 두 알고리즘의 결과를 시뮬레이션을 통하여 비교 검토함으로써 ‘진화적 게임 이론(Evolutionary Game Theory : EGT)’의 두 가지 아이디어 -‘내쉬의 균형(Equilibrium)’과 ‘진화적 안정전략(Evolutionary Stable Strategy . ESS)’-에 기반한 최적화 알고리즘들이 다목적 함수 문제의 최적해를 탐색할 수 있음을 확인한다.

A Study on Implementation of Linear 25Watts High Power Amplifier for VDR (VDR을 위한 선형 25Watts 고출력 증폭기 구현에 관한 연구)

  • Choi, Jun-Su;Hur, Chang-Wu
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2011.10a
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    • pp.389-391
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    • 2011
  • This paper has been studied about design of linear 25Watt Power amplifier for VDR(VHF Data Radio). VDR's frequency band is 117.975~137MHz, and CSMA(Carrier Sense Multiple Access), D8PSK(Differential Eight Phase Shift Keyed), 25KHz's channel bandwidth use. It also stated in DO-281A MOPS output power, symbol constellation error, spurious emissions, adjacent channel power must be met. HPA is designed to meet DO-281A standard.

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A Study on the TPM for Performance Management of Weapon System R&D Program (무기체계 연구개발 사업의 성능관리를 위한 기술성과측정에 관한 연구)

  • Hur, Jang-Wook;Noh, Hyun-Il
    • Journal of the Korea Institute of Military Science and Technology
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    • v.13 no.4
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    • pp.612-618
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    • 2010
  • In order to successfully manage of the state-of-the-art weapon system R&D program which are under the limited budget and schedule but also has a high level of technical risks, it is gaining weights to use such a scientific program management tool as TPM. Therefore, the purpose of this research is to review the concept of the TPM and its relation among MOE, MOP and TPM, and introduce an application method of TPM mainly focusing on helicopter development program. It has the organized structure, detailed procedure and 282 parameters for performance management through the TPM.

Intramolecular Ring-Ring Stacking Interartions between 8-Methoxypsoralen and Adenine Induced by Polymethylene Bridges.

  • Yu, Dong Jin;Hyeon, Seung Hak;Sim, Sang Cheol
    • Bulletin of the Korean Chemical Society
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    • v.22 no.6
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    • pp.575-580
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    • 2001
  • Intramolecular ring-ring interactions in the model compounds, $8-methoxypsoralen-CH_2O(CH_2)n-adenine(MOPCH_2OCnAd$, n=2, 3, 5, and 6) in which 5' position of 8-methoxypsoralne (8-MOP) is linked by different polymethylene bridges to N9 of adenine, have been investigated by hypochromism measurements. Efficient ring-ring stacking interactions have been observed in $MOPCH_2CO2Ad$ (7) from the percent hypochromism(%H) and fluorescence spectra of the models and a reference molecule. The 8-methoxyposralen-adenine systems have shown stronger ring-ring stacking interaction than the psoralen-adenine system.

A Global Compaction of Microprograms Using Triangular Matrices and Junctiuon Blocks (삼각행렬과 접합블럭을 이용한 마이크로프로그램의 광역적 최적화)

  • Choi, Ki Ho;Lim, In Chil
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.23 no.5
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    • pp.681-691
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    • 1986
  • To represent the relations of the data dependency and resource conflict among micro-operations(MOP's) in the compaction process of microprograms, we propose a DDM (data dependent matrix) representation method instead of the DAG (conventional directed acyclic graph). Also, we propose a global compaction algorithm of microprograms to prevent a kind of block copying by cutting the trace at a junction block. The DDM method and compaction algoristhm have been applied to the Lah's example. The results shows that the proposed algorithm is more efficient than the conventional algorithms in reducing in reducing the total execution time and control memory space.

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Relative Photoreactivity of 5,7-Dimethoxycoumarin and cis-syn 8-MOP $<\array{4^{\prime},5\\5^{\prime},6}>$ Thd Monoadduct to Thymidine in a Dry Film State

  • Shim, Sang-Chul;Kang, Ho-Kwon
    • Bulletin of the Korean Chemical Society
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    • v.7 no.4
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    • pp.289-293
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    • 1986
  • The photocycloaddition reactivity of 5,7-dimethoxycoumarin (DMC) to thymidine is much higher than that of cis-syn 8-methoxypsoralen $<\array{4^{\prime},5\\5^{\prime},6}>$ thymidine monoadducts, due to the steric effect. The different rate is also due to the relative reactivity of the singlet rather than the triplet excited state of the compounds. The biadducts of 8-methoxypsoralen and thymidine are first splitted into 4',5'-monoadducts and thymidine, not into 3,4'-monoadducts and thymidine by 254 nm light.

A Study on the Framework for Analyzing the Effectiveness of Cyber Weapon Systems Associated with Cyberspace and Physical Space (사이버 공간과 물리 공간이 연계된 사이버 무기체계의 효과성 분석 프레임워크 연구)

  • Jang, Ji-su;Kim, Kook-jin;Yoon, Suk-joon;Park, Min-seo;Ahn, Myung-Kil;Shin, Dong-kyoo
    • Journal of Internet Computing and Services
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    • v.23 no.5
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    • pp.111-126
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    • 2022
  • As operations that were only conducted in physical space in the past change to operations that include cyberspace, it is necessary to analyze how cyber attacks affect weapon systems using cyber systems. For this purpose, it would be meaningful to analyze a tool that analyzes the effects of physical weapon systems in connection with cyber. The ROK military has secured and is operating the US JMEM, which contains the results of analyzing the effects of physical weapon systems. JMEM is applied only to conventional weapon systems, so it is impossible to analyze the impact of cyber weapon systems. In this study, based on the previously conducted cyber attack damage assessment framework, a framework for analyzing the impact of cyber attacks on physical missions was presented. To this end, based on the MOE and MOP of physical warfare, a cyber index for the analysis of cyber weapon system effectiveness was calculated. In addition, in conjunction with JMEM, which is used as a weapon system effect manual in physical operations, a framework was designed and tested to determine the mission impact by comparing and analyzing the results of the battle in cyberspace with the effects of physical operations. In order to prove the proposed framework, we analyzed and designed operational scenarios through domestic and foreign military manuals and previous studies, defined assets, and conducted experiments. As a result of the experiment, the larger the decrease in the cyber mission effect value, the greater the effect on physical operations. It can be used to predict the impact of physical operations caused by cyber attacks in various operations, and it will help the battlefield commander to make quick decisions.

The Effect of Process Models on Short-term Prediction of Moving Objects for Autonomous Driving

  • Madhavan Raj;Schlenoff Craig
    • International Journal of Control, Automation, and Systems
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    • v.3 no.4
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    • pp.509-523
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    • 2005
  • We are developing a novel framework, PRIDE (PRediction In Dynamic Environments), to perform moving object prediction (MOP) for autonomous ground vehicles. The underlying concept is based upon a multi-resolutional, hierarchical approach which incorporates multiple prediction algorithms into a single, unifying framework. The lower levels of the framework utilize estimation-theoretic short-term predictions while the upper levels utilize a probabilistic prediction approach based on situation recognition with an underlying cost model. The estimation-theoretic short-term prediction is via an extended Kalman filter-based algorithm using sensor data to predict the future location of moving objects with an associated confidence measure. The proposed estimation-theoretic approach does not incorporate a priori knowledge such as road networks and traffic signage and assumes uninfluenced constant trajectory and is thus suited for short-term prediction in both on-road and off-road driving. In this article, we analyze the complementary role played by vehicle kinematic models in such short-term prediction of moving objects. In particular, the importance of vehicle process models and their effect on predicting the positions and orientations of moving objects for autonomous ground vehicle navigation are examined. We present results using field data obtained from different autonomous ground vehicles operating in outdoor environments.

A study on specification of high power amplifier for MOPS (MOPS 규격을 만족하기 위한 고출력증폭기 특성 연구)

  • Choi, Jun-Su;Hur, Chang-Wu
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.15 no.11
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    • pp.2451-2456
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    • 2011
  • This paper is a study on the high power amplifier to fulfill standards of the MOPS. VDR's frequency band is 117.975~137MHz, and CSMA(Carrier Sense Multiple Access), D8PSK(Differential Eight Phase Shift Keyed), 25KHz's channel bandwidth use. It also stated in DO-281A MOPS output power, symbol constellation error, spurious emissions, adjacent channel power must be met. We designed and measured the performance. The 38dB of the IM3 satisfies the MOPS standard.