• Title/Summary/Keyword: MODCS

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Orientia tsutsugamushi Infection Induces $CD4^+$ T Cell Activation via Human Dendritic Cell Activity

  • Chu, Hyuk;Park, Sung-Moo;Cheon, In Su;Park, Mi-Yeoun;Shim, Byoung-Shik;Gil, Byoung-Cheol;Jeung, Woon Hee;Hwang, Kyu-Jam;Song, Ki-Duk;Hong, Kee-Jong;Song, Manki;Jeong, Hang-Jin;Han, Seung Hyun;Yun, Cheol-Heui
    • Journal of Microbiology and Biotechnology
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    • v.23 no.8
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    • pp.1159-1166
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    • 2013
  • Orientia tsutsugamushi, a gram-negative bacterium, causes severe acute febrile illness in humans. Despite this danger, the route of infection, infectivity, and protective mechanisms of the host's immune response to O. tsutsugamushi are unclear. Dendritic cells (DCs) are one of the most important cell types in bridging the innate and adaptive immune responses. In this study, we observed that O. tsutsugamushi infects and replicates in monocyte-derived DCs (MODCs). During infection and replication, the expressions of the cytokines IL-12 and TNF-${\alpha}$, as well as the co-stimulatory molecules CD80, CD83, CD86, and CD40, were increased in MODCs. When O. tsutsugamushi-treated MODCs were co-cultured with autologous $CD4^+$ T cells, they enhanced production of IFN-${\gamma}$, a major Th1 cytokine. Collectively, our results show that O. tsutsugamushi can replicate in MODCs and can simultaneously induce MODC maturation and increase proinflammatory cytokine levels in MODCs that subsequently activate $CD4^+$ T cells.

Auto-compatibility Analysis for Ka-band payload of COMS

  • Park, Jae-Woo;Lee, Seong-Pal;Baek, Myung-Jin
    • Journal of Satellite, Information and Communications
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    • v.2 no.2
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    • pp.41-47
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    • 2007
  • The first geostationary satellite made by Korea, COMS, has the three different payload ; Meteorological sensor, Oceanographic sensor and Ka-band communication payload. There are Meteorological & Ocean Data Communication Subsystem(MODCS) and Telemetry, Command and Ranging Subsystem(TC&R) as other RF radiation sources. MODCS transmits and receives Meteo and Ocean measurement data from/to earth using L-band and TC&R using S-band. The Ka-band communication payload will provide high-speed multimedia services and communication services for natural disaster such as prediction, prevention, and recovery services in the government communications network.Ka-band beacon is for the earth antenna pointing and the experiment of rain fading. This paper gives the analysis results about the mutual radiation effect on Ka-band communication payload, Ka-band beacon, MODCS and TC&R. Up/Down link power and coupling factor including the geometrical position and distance of antenna, filter rejection and degradation factor due to the different polarization are considered. The results show MODCS and TC&R are compatible for Ka-band communication payload and Ka-band beacon does not interfere with MODCS and TC&R normal operation.

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A Preliminary Performance Analysis of the Meteorological and Ocean Data Communication Subsystem in COMS (통신해양기상위성 기상해양데이터통신계의 예비 성능 해석)

  • Kim, Jung-Pyo;Yang, Gun-Ho
    • Journal of Satellite, Information and Communications
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    • v.1 no.2
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    • pp.25-31
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    • 2006
  • The COMS (Communication, Ocean, and Meteorological Satellite) performing meteorological and ocean monitoring and providing communication service with meteorological, ocean and Ka-band payload in the geostationary orbit includes MODCS (Meteorological and Ocean Data Communication Subsystem) which provides transmitting the raw data collected by meteorological payload called MI (Meteorological Imager) and ocean payload named GOCI (Geostationary Ocean Color Imager) to the ground station and relaying the meteorological data processed on the ground to the end-user stations. MODCS comprises of two channels: SD channel which formats the raw data according to CCSDS recommendation, amplifies and transmits its signal to the ground station; MPDR channel which relays to the end-user stations the ground-processed meteorological data in the data format of LRIT/HRIT recommended by CGMS. This paper constructs the architecture of MODCS for transmitting and relating the observed data, and investigates that the key performance parameters have the required margin through the preliminary performance analyses.

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SETTING OF HPA OUTPUT POWER IN COMS DATS CONSIDERING IMD CHARACTERISTICS

  • Park, Durk-Jong;Yang, Hyung-Mo;Ahn, Sang-Il
    • Proceedings of the KSRS Conference
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    • v.1
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    • pp.204-207
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    • 2006
  • COMS will receive two different meteorological signals in S-Band from IDACS (Image Data Acquisition and Control System) in ground station before transmitting them in L-Band to user station. MODCS (Meteorological Ocean Data Communication Subsystem) in satellite released the value of required PFD (Power Flux Density) to receive two signals. Thus, DATS (Data Acquisition and Transmission Subsystem) needs to send two signals to satellite with a satisfied EIRP. The value of minimum HPA (High Power Amplifier) output power was estimated by subtracting antenna directional gain and path loss between antenna and HPA from the needed EIRP in this paper. Besides the minimum output power of HPA, the maximum output power was also calculated with considering IMD (Inter-Modulation Distortion) characteristics. IMD is always occurred in the output of HPA when LRIT and HRIT are amplified by using single HPA as COMS application. In this paper, the setting of maximum output power was determined when the IMD of modelled HPA was corresponded to the requirement of MODCS.

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Design of RF Supporting Unit for COMS RF Compatibility Test (COMS RF호환성 시험을 위한 RF지원 장비의 설계 및 제작)

  • Park, Durk-Jong;Park, Chun-Woo;Ahn, Sang-Il
    • Aerospace Engineering and Technology
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    • v.7 no.2
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    • pp.176-186
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    • 2008
  • As determined single coaxial cable for the interface between satellite and ground station in COMS RF compatibility test, RF supporting unit was required to allow signals in different frequency-band to be exchanged in the single coaxial cable. In addition, the path loss between satellite and ground station in normal operation should be simulated through two RF supporting units connected to the ends of single coaxial cable. As an effort to design RF supporting unit, level diagram was firstly conducted on the basis of measured data for each element. From the level diagram, it was found that single coaxial cable connected with two RF supporting units properly represented the path loss between satellite and ground station After RF supporting unit was integrated on aluminum plate, it was tested that input signal level at each test cap linked with MODCS and TC&R was tunable within the required dynamic range. RF supporting unit, now completely integrated, will be applied in the upcoming COMS RF compatibility test.

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Combined Gain Analysis of L-band Transmit Antenna in COMS (COMS L-대역 송신 안테나 합성 이득 해석)

  • Kim, Joong-Pyo;Yang, Koon-Ho;Lee, Sang-Kon
    • Journal of Satellite, Information and Communications
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    • v.5 no.2
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    • pp.19-24
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    • 2010
  • The COMS (Communication Ocean Meteorological Satellite) is a hybrid geostationary satellite including communication, ocean, and meteorological payloads. The COMS includes the MODCS (Meteorological and Ocean Data Communication Subsystem) which provides transmitting the raw data collected by meteorological payload called MI (Meteorological Imager) and ocean payload named GOCI (Geostationary Ocean Color Imager) to the ground station, and relaying the meteorological data processed on the ground to the end-user stations. Here, for the L-band transmit antenna transmitting SD (Sensor Data) signal and the processed signal, from the system point of view, it is required to estimate the combined antenna gain when the L-band transmit is placed with MI and GOCI payloads on the earth panel of COMS. First of all, the L-band transmit horn is designed and analyzed for the requirements given, and then after placing it on the earth panel, the combined gain analysis is performed using three different analysis methods. It's shown that the obtained gain patterns are very similar among three different analysis methods. Finally the antenna gain degradation of less than 0.5 dB is estimated.

A Study of Payload Interface Unit Design for COMS (Communication Ocean & Meteorological Satellites) (통신해양기상위성의 탑재체 접속장치 설계에 관한 연구)

  • Cho, Young-Ho;Won, Joo-Ho;Choi, Jae-Dong;Yang, Koon-Ho
    • Proceedings of the KIEE Conference
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    • 2008.10b
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    • pp.369-370
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    • 2008
  • The Payload Interface Unit (PIU) provides the interface between payload equipment (GOCI, MODCS and Ka Band P/L) and the SCU. The PIU is a MIL-STD-1553-Bus Remote Terminal (RT). The MPIU distributes commands to, acquires telemetry from and takes part in the thermal control of the payload equipment. When in ON mode, the PIU is completely observable and can be used for payload control. When in OFF mode, the PIU is non active except the thermal control electronics.

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