• Asian Pacific Journal of Cancer Prevention
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• 제17권9호
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• pp.4323-4326
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• 2016

Background: The cancer mortality-to-incidence ratio (MIR) has been established as an important measure of health disparities in local and global circumstances. Past work has corroborated a linkage between the colorectal cancer MIR and the World Health Organization (WHO) Health System ranking. The literature further documents many Asian countries having incomplete cancer registries and a lack of comprehensive colorectal cancer screening guidelines. Materials and Methods: The colorectal cancer MIR values for 23 Asian countries were calculated from data obtained from the 2012 GLOBOCAN database. The 2000 World Health Organization (WHO) Health System rankings were used as a proxy for health system infrastructure and responsiveness. A regression equation was calculated with the MIR as the dependent variable and the WHO Health System ranking as the independent variable. Predicted MIR values were next calculated based on the regression results. Actual MIR values that exceeded 0.20 from the predicted MIR were removed as 'divergent' points. The regression equation was then re-plotted. Goodness-of-fit for both regressions was assessed by the R-squared test. Results: Asian countries have a relatively wide colorectal cancer MIR range, from a minimum of 0.24 to a maximum of 0.86. For the full dataset, the adjusted R-squared value for this regression was 0.53. The equation was then used to calculate a predicted MIR, whereby two data points were identified as 'divergent' and removed. The adjusted R-squared for the edited dataset increased to 0.66. Conclusions: Asian countries have a marked range in their colorectal cancer MIR values and there is a strong correlationwith the WHO Health System ranking. These results corroborate the contribution of the MIR as a potentially robust tool in monitoring changes in colorectal cancer care for Asian nations.

• 융합보안논문지
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• 제6권1호
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• pp.25-32
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• 2006

본 논문에서 제시되는 MIR 시스템은 의료정보를 필요로 하는 어느 병원에서나 보건기관에서 즉시 사용할 수 있도록 전국적인 의무기록 정보 시스템을 구축하는 것으로 대부분 보안이 요구되는 자료들이다. 특히, 환자와 의사에 관련된 개인정보, 의료 전문기술 관련정보, 각 병원의 전산적 정보는 사용 빈도가 높고 정보의 변질을 통해 다른 목적으로 이용될 수 있는 가능성이 높다. 따라서 이러한 의료정보 서비스를 효과적으로 제공함과 동시에 정보의 유출을 방지하기 위한 보안대책이 강구된 시스템 개발이 필요하다.

• Journal of Information Processing Systems
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• 제14권1호
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• pp.32-55
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• 2018

The digitization of music has seen a considerable increase in audience size from a few localized listeners to a wider range of global listeners. At the same time, the digitization brings the challenge of smoothly retrieving music from large databases. To deal with this challenge, many systems which support the smooth retrieval of musical data have been developed. At the computational level, a query music piece is compared with the rest of the music pieces in the database. These systems, music information retrieval (MIR systems), work for various applications such as general music retrieval, plagiarism detection, music recommendation, and musicology. This paper mainly addresses two parts of the MIR research area. First, it presents a general overview of MIR, which will examine the history of MIR, the functionality of MIR, application areas of MIR, and the components of MIR. Second, we will investigate music similarity measurement methods, where we provide a comparative analysis of state of the art methods. The scope of this paper focuses on comparative analysis of the accuracy and efficiency of a few key MIR systems. These analyses help in understanding the current and future challenges associated with the field of MIR systems and music similarity measures.

• Asian Pacific Journal of Cancer Prevention
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• 제15권18호
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• pp.7547-7552
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• 2014

The mir-155 family is not only involved in a diversity of cancers, but also as a regulator of the immune system. However, the evolutionary history of this family is still unclear. The present study indicates that mir-155 evolved independently with lineage-specific gain of miRNAs. In addition, arm switching has occurred in the mir-155 family, and alternative splicing could produce two different lengths of ancestral sequences, implying the alternative splicing can also drive evolution for intragenic miRNAs. Here we screened validated target genes and immunity-related proteins, followed by analyzation of the mir-155 family function by high-throughput methods like the gene ontology (GO) and Kyoto Eneyclopedin of Genes and Genemes (KEGG) pathway enrichment analysis. The high-throughput analysis showed that the CCND1 and EGFR genes were outstanding in being significantly enriched, and the target genes cebpb and VCAM1 and the protein SMAD2 were also vital in mir-155-related immune reponse activities. Therefore, we conclude that the mir-155 family is highly conserved in evolution, and CCND1 and EGFR genes might be potential targets of mir-155 with regard to progress of cancers, while the cebpb and VCAM1 genes and the protein SMAD2 might be key factors in the mir-155 regulated immune activities.

• Food Science and Biotechnology
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• 제18권5호
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• pp.1118-1123
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• 2009

Event-specific real-time polymerase chain reaction (PCR) detection method for genetically modified (GM) maize MIR604 was developed based on integration junction sequences between the host plant genome and the integrated transgene. In this study, 2 primer pairs and probes were designed for specific amplification of 100 and 111 bp DNA fragments from the zSSIIb gene (the maize endogenous reference gene) and MIR604. The quantitative method was validated using 3 certified reference materials (CRMs) with levels of 0.1, 1, and 10% MIR604. The method was also assayed with 14 different plants and other GM maize. No amplification signal was observed in real-time PCR assays with any of the species tested other than MIR604 maize. As a result, the bias from the true value and the relative deviation for MIR604 was within the range from 0 to 9%. Precision, expressed as relative standard deviation (RSD), varied from 2.7 to 10% for MIR604. Limits of detections (LODs) of qualitative and quantitative methods were all 0.1%. These results indicated that the event-specific quantitative PCR detection system for MIR604 is accurate and useful.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2009년도 제38회 동계학술대회 초록집
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• pp.127-127
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• 2010

Owing to many advantages on indirect intersubband absorption from the hole miniband to the electron miniband based on the type-II band alignment in InAs/GaSb strained-layer superlattice (SLS), InAs/GaSb SLS infrared photodetector (SLIP) has emerged as a promising system to realize high-detectivity quantum photodetector operating up to room temperature in the spectral range of mid-infrared (MIR) to far-infrared (FIR). In particular, n-barrier-n (n-B-n) structure designed for blocking the majority-carrier dark current makes it possible for MIR/FIR dual-band SLIP whose photoresponse (PR) band can be exclusively selected by the bias polarity. In this study, we present the MIR and FIR photoresponse (PR) mechanism identified by dual-band PR spectra and photoluminescence (PL) profiles taken from InAs/GaSb SLIP. In the MIR/FIR PR spectra measured by changing bias polarity, each spectrum individually shows a series of distinctive peaks related to the transitions from the hole subbands to the conduction one. The PR mechanism at each polarity is discussed in terms of diffusion current, and a superposition of MIR-PR in the FIR-PR spectrum is explained by tunnelling of electrons activated in MIR-SLS. The effective FIR-PR spectrum decomposed into three curves for HH1, LH1, and HH2 has revealed the edge energies of 120, 170, and 220 meV, respectively, and the temperature variation of the MIR-PR edge energies shows that the temperature behavior of the SLS systems can be approximately expressed by the Varshni empirical equation.

• Korean Journal of Acupuncture
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• 제24권4호
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• pp.55-67
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• 2007

Objectives : The repeatability and reproducibility of MIR-2, a newly developed impedance measurement device (four electrode method) on skin are of the meridian system, is evaluated and a method to improve the reliability is discussed. Methods : Multiple gage R&R studies were conducted for the impedance measurements over bilateral KI3 acupoint in ten participants by three assessors using MIR-2 device. Gage R&R studies were repeated after controlling the acupoint locating method or one value correction by replacing one assessor's outlying value with an average of the other assessors' values to explore any feasibility of improvement of measurement reliability. Results : Controlling acupoint locating method and replacing one value with an average of other assessors' value led to improved variation metrics in a gage R&R study. Conclusions : Measurement reliability can be improved by controlling measurement procedures or by using repeated measurement method, which will facilitate development of clinically applicable measurement device with reliability.

• 대한안전경영과학회:학술대회논문집
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• 대한안전경영과학회 2004년도 추계학술대회
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• pp.253-258
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• 2004

Domestic construction industry (including plant engineering industry) faces severe competition with world-wide leading companies under WTO (World Trade Organization) system. To survive in this competition, domestic construction company should establish and operate standardization system efficiently. In this paper, check list is presented to prepare the efficient reliability management system in domestic construction. And then, the check list is applied in MIR(Maturity Index on Reliability) estimation item to estimate reliability management level of company quantitatively.

• 대한원격탐사학회지
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• 제29권1호
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• pp.95-104
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• 2013

3-5 ${\mu}m$ 파장대의 중적외선 영상으로부터 정밀한 절대온도를 추정하기 위해서는 지표 복사율, 대기효과, 낮 영상의 경우 반사되는 태양빛에 대한 정보를 필요로 하며, 이는 온도 추정 시 오차를 발생시키는 주요 원인이 된다. 이 연구는 이를 해결하기 위해 상대적인 온도 차이를 추정하는 방법을 제안하고자 한다. 제안된 알고리즘의 기본 방향은 온도 추정을 위한 입력자료를 최소화 시키는 것이다. 이를 위해 인접한 지역에 위치한 두 대상물체가 받는 대기효과는 동일하다고 가정하였으며 MODTRAN 및 ASTER spectral library로부터 입력자료를 단순화 시키는 연구가 수행되었다. 시뮬레이션 연구 결과 제안된 상대온도추정알고리즘의 정밀도는 300 K의 온도에서 0.1의 지표 복사율 오차에 대해 2 K 이내의 비교적 높은 정밀도를 나타냈다. 그러나 낮 영상에서 저온인 경우에는 정밀도가 크게 감소하였다. 알고리즘의 검증을 위해 MODIS band 23 중적외선 낮 영상에 적용하였으며, 이를 MODIS LST 자료와 비교를 수행한 결과 $0.485{\pm}1.552$ K의 오차를 나타내었다. 이 결과로부터 제안된 알고리즘이 외부 입력자료를 필요로 하지 않고 단지 영상 만으로부터 비교적 높은 정밀도로 온도 추정이 가능함을 보였다. 그러나 제안된 알고리즘은 상대온도만을 알 수 있으며, 절대온도를 추정하기 위해서는 기준온도에 대한 정보가 필요하다는 한계점도 있다.

• 대한안전경영과학회지
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• 제6권2호
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• pp.103-114
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• 2004

IEC 60300 series, the international standards on reliability management system are newly developed and introduced rapidly worldwide. In order to meet this fast-changing situation, it is necessary to apply them to the Korean industries effectively. It includes the establishment of the infrastructure such as documentation of Korean Standards, introduction of test equipments and test manuals, accreditation of the certification bodies and training of the specialists etc. IEC 60300 is upgraded management system of the ISO 9000 and ISO 14000. In this regard, the Korean companies which were certified with the ISO 9000 or 14000 should endeavor to find new strategies and methods to be certified with IEC 60300. This paper introduces a Quantitative method of estimating the level of the reliability management system by applying the MIR(Maturity Index on Reliability) technique. This enables the estimation of the operation level of the system and can upgrade the maturity level of it.