• Journal of the Korean Association of Geographic Information Studies
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• v.15 no.2
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• pp.113-125
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• 2012

This research is aimed at evaluating the land surface characterization of KOMPSAT-3A middle infrared (MIR) data. Airborne Hyperspectral Scanner (AHS) data, which has MIR bands with high spatial resolution, were used to assess land surface temperature (LST) retrieval and classification accuracy of MIR bands. Firstly, LST values for daytime and nighttime, which were calculated with AHS thermal infrared (TIR) bands, were compared to digital number of AHS MIR bands. The determination coefficient of AHS band 68 (center wavelength $4.64{\mu}m$) was over 0.74, and was higher than other MIR bands. Secondly, The land cover maps were generated by unsupervised classification methods using the AHS MIR bands. Each class of land cover maps for daytime, such as water, trees, green grass, roads, roofs, was distinguished well. But some classes of land cover maps for nighttime, such as trees versus green grass, roads versus roofs, were not separated. The image classification using the difference images between daytime AHS MIR bands and nighttime AHS MIR bands were conducted to enhance the discrimination ability of land surface for AHS MIR imagery. The classification accuracy of the land cover map for zone 1 and zone 2 was 67.5%, 64.3%, respectively. It was improved by 10% compared to land cover map of daytime AHS MIR bands and night AHS MIR bands. Consequently, new algorithm based on land surface characteristics is required for temperature retrieval of high resolution MIR imagery, and the difference images between daytime and nighttime was considered to enhance the ability of land surface characterization using high resolution MIR data.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.18
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• pp.7547-7552
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• 2014

The mir-155 family is not only involved in a diversity of cancers, but also as a regulator of the immune system. However, the evolutionary history of this family is still unclear. The present study indicates that mir-155 evolved independently with lineage-specific gain of miRNAs. In addition, arm switching has occurred in the mir-155 family, and alternative splicing could produce two different lengths of ancestral sequences, implying the alternative splicing can also drive evolution for intragenic miRNAs. Here we screened validated target genes and immunity-related proteins, followed by analyzation of the mir-155 family function by high-throughput methods like the gene ontology (GO) and Kyoto Eneyclopedin of Genes and Genemes (KEGG) pathway enrichment analysis. The high-throughput analysis showed that the CCND1 and EGFR genes were outstanding in being significantly enriched, and the target genes cebpb and VCAM1 and the protein SMAD2 were also vital in mir-155-related immune reponse activities. Therefore, we conclude that the mir-155 family is highly conserved in evolution, and CCND1 and EGFR genes might be potential targets of mir-155 with regard to progress of cancers, while the cebpb and VCAM1 genes and the protein SMAD2 might be key factors in the mir-155 regulated immune activities.

• Proceedings of the KSRS Conference
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• 2008.03a
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• pp.125-130
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• 2008

Mid-Infrared (MIR) 영상은 화산 활동 및 산불로 인한 재난관측, 지표물질 관측, 해수 온도 측정과 같은 분야들에서 사용되고 있다. 그러나 MIR영역은 지표의 복사율과 대기의 영향으로 인한 변화가 매우 심하고, 낮 영상의 경우 태양 복사량에 의한 영향도 고려해야 하는 어려움이 있다. 따라서 단일밴드인 MIR영상을 이용하여 표면온도를 얻기 위해서는 영상이 취득된 시간과 장소에서 관측된 태양 복사량 및 여러 가지 대기 변수가 필요하다. 본 연구의 목적은 기존의 MIR 영상 연구가 다중밴드를 기반으로 한 것과 달리 단일 밴드의 영상을 이용하여 표면온도를 측정하는데 있다. 이를 위하여 MODIS MIR 영상을 대상으로 MODTRAN을 사용하여 MIR 영역의 대기보정 기법을 적용 한 뒤 복사전달 모델을 이용하여 지표의 복사량을 측정하였다. 획득된 지표온도 영상의 정밀도를 측정하기 위해서 기존의 온도 알고리즘인 split-window algorithm에 의해 얻어진 해수온도 영상과의 비교를 통하여 오차 원인에 대해 분석을 실시하였다. 그 결과 낮 영상의 경우 -4.19${\pm}$1.19$^{\circ}C$ 정도의 온도 차가 났으며, 밤 영상의 경우 0.5$^{\pm}C$0.39$^{\circ}C$ 정도로 비교적 좋은 결과를 보였다. 이는 낮 영상의 경우 지표의 복사율에 대한 온도의 민감도가 매우 높기 때문에 높은 오차가 발생하지만, 밤 영상의 경우 태양빛에 의한 영향이 없으므로 좋은 결과를 나타내기 때문이다. 따라서 단일밴드 MIR영상을 이용한 지표온도 추정 시 대기에 의한 영향보다 지표 복사율에 의한 영향이 높다고 추정할 수 있다.

• Proceedings of the Korean Vacuum Society Conference
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• 2010.02a
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• pp.127-127
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• 2010

Owing to many advantages on indirect intersubband absorption from the hole miniband to the electron miniband based on the type-II band alignment in InAs/GaSb strained-layer superlattice (SLS), InAs/GaSb SLS infrared photodetector (SLIP) has emerged as a promising system to realize high-detectivity quantum photodetector operating up to room temperature in the spectral range of mid-infrared (MIR) to far-infrared (FIR). In particular, n-barrier-n (n-B-n) structure designed for blocking the majority-carrier dark current makes it possible for MIR/FIR dual-band SLIP whose photoresponse (PR) band can be exclusively selected by the bias polarity. In this study, we present the MIR and FIR photoresponse (PR) mechanism identified by dual-band PR spectra and photoluminescence (PL) profiles taken from InAs/GaSb SLIP. In the MIR/FIR PR spectra measured by changing bias polarity, each spectrum individually shows a series of distinctive peaks related to the transitions from the hole subbands to the conduction one. The PR mechanism at each polarity is discussed in terms of diffusion current, and a superposition of MIR-PR in the FIR-PR spectrum is explained by tunnelling of electrons activated in MIR-SLS. The effective FIR-PR spectrum decomposed into three curves for HH1, LH1, and HH2 has revealed the edge energies of 120, 170, and 220 meV, respectively, and the temperature variation of the MIR-PR edge energies shows that the temperature behavior of the SLS systems can be approximately expressed by the Varshni empirical equation.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.5
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• pp.1781-1787
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• 2015

Background: miRNAs are relatively recently discovered cancer biomarkers which have important implications for cancer early diagnosis, treatment and estimation of prognosis. Here we focussed on expression of mir-196a-5p in gastric cancer tissues and cell lines so as to analyse its significance for clinicopathologic characteristics and generate enriched KEGG pathways clustered by target genes for exploring its potential roles as a biomarker in gastric cancer. Materials and Methods: The expression of mir-196a-5p in poorly, moderate and well differentiated gastric cancer cell lines compared with GES-1 was detected by RT-qPCR, and the expression of mir-196a-5p in gastric cancer tissues comparing with adjacent non cancer tissues of 58 cases were also assessed by RT-qPCR. Subsequently, an analysis of clinical significance of mir-196a-5p in gastric cancer and enriched KEGG pathways was executed based on the miRWalk prediction database combined with bioinformatics tools DAVID 6.7 and Mirfocus 3.0. Results: RT-qPCR showed that mir-196a-5p was up-regulated in 6 poorly and moderate differentiated gastric cancer cell lines SGC-7901, MKN-45, MKN-28, MGC-803, BGC-823, HGC-27 compared with GES-1, but down-regulated in the highly differentiated gastric cancer cell line AGS. Clinical data indicated mir-196a-5p to beup-regulated in gastric cancer tissues (47/58). Overexpression of mir-196a-5p was associated with more extensive degree of lymph node metastasis and clinical stage (P < 0.05; x2 test). Enriched KEGG pathway analyses of predicted and validated targets in miRWalk combined with DAVID 6.7 and Mirfocus 3.0 showed that the targeted genes regulated by mir-196a-5p were involved in malignancy associated biology. Conclusions: Overexpression of mir-196a-5p is associated with lymph node metastasis and clinical stage, and enriched KEGG pathway analyses showed that targeted genes regulated by mir-196a-5p may contribute to tumorgenesis, suggesting roles as an oncogenic miRNA biomarker in gastric cancer.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.7
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• pp.3369-3375
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• 2016

MicroRNAs, a novel class of small non-coding RNAs, are key players in many cellular processes, including cell proliferation, differentiation, invasion and regeneration. Tissue and circulatory microRNAs could serve as useful clinical biomarkers and deregulated expression levels have been observed in various cancers. Gene variants may alter microRNA processing and maturation. Thus, we aimed to investigate the association of MIR-196a2 rs11614913 (C/T), MIR-499a rs3746444 (A/G) polymorphisms and their combination with cancer susceptibility in an Egyptian population. Sixty five renal cell carcinoma (RCC) and 60 hepatocellular carcinoma (HCC) patients and 150 controls were enrolled in the study. They were genotyped using real-time polymerase chain reaction technology. Both $miR-196a2^*T$ and $miR-499a*G$ were associated with RCC risk, but only $miR-196a^*T$ was associated with HCC development. Carriage of the homozygote combinations ($MIR196a2^*TT+MIR499a^*AA$) and ($MIR196a2^*CC+MIR499a^*GG$) was associated with 25 and 48 fold elevation of likelhood to develop RCC, respectively. The miR-196a2 SNP was also linked with larger tumor size in RCC and advanced tumor stage in HCC. miR-196a2 and miR-499a combined genotypes were associated with RCC and HCC. Further functional analysis of SNPs is required to confirm relationships between genotypes and phenotypes.

• The Bulletin of The Korean Astronomical Society
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• v.40 no.1
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• pp.76.3-77
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• 2015

MIR colors are an excellent tool to investigate the transition phase of galaxy evolution in terms of star formation at various phases. The Coma supercluster is the nearest massive supercluster, hosting two main clusters, the Coma (Abell 1656) and Leo (Abell 1367) clusters, and one galaxy group, the NGC 4555 group, providing an ideal laboratory to study how galaxies evolve depending on environment. We present the results of a study for MIR properties of galaxies in the Coma supercluster using multi-wavelength data from the optical to MIR including the Sloan Digital Sky Survey Data Release 12 and the Wide-field Infrared Survey Explorer. We investigate differences in MIR properties of galaxies among three galaxy systems, and discuss the results in relation with star formation history and morphological transformation of galaxies.

• Convergence Security Journal
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• v.6 no.1
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• pp.25-32
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• 2006

MIR system is a nationwide medical record information system that makes medical information available to any hospital and health institution at any time, and information in the system mostly requires high security. In particular, personal information related to patients and doctors, medical technology information and each hospital's digital information are used very frequently and are likely to be modified for illegal use. Thus we need to develop a system equipped with security measures to prevent information leakage while providing medical information service effectively.

• Food Science and Biotechnology
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• v.17 no.3
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• pp.569-572
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• 2008

A multiplex polymerase chain reaction (PCR) method was developed to simultaneously detect 3 events of genetically modified (GM) maize. The event-specific primers were used to discriminate the following 3 events of GM maize (DAS-59122-7, TC6275, and MIR604) using multiplex PCR method. The zein gene was used as an endogenous maize reference gene in the multiplex PCR detection. The primer pair Zein-FIR producing a 99 bp amplicon was used to amplify the zein gene. The primer JI-Das-F1/R1 for DAS-59122-7, JI-TC6275-F3/R3 for TC6275, and JI-MIR F1/R1 for MIR604 yielded an amplicon of 130, 162, and 197 bp, respectively. The detection limit of multiplex PCR was 1% for DAS-59122-7, TC6275, and MIR604 for one reaction.

• Archives of Plastic Surgery
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• v.42 no.3
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• pp.356-360
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• 2015

In plastic surgery, patient photography is a vital component of clinical, educational, legal, and research documentation. Optimal acquisition of photographic data requires a dedicated photography studio or a three-dimensional anatomic scanner, both of which are financially impractical for most clinicians. Simplified photo standardization is proposed for use in random clinical settings by using a portable device called the Mirror Stand (MirS). This model device aims to mimic a studio environment by incorporating the basic elements of producing consistent photographs. The pilot MirS is designed for facial photography. Images of 40 random subjects were obtained using the MirS with three different cameras. Real anthropometric measurements of each subject were collected, compared with the photographic measurements, and analyzed. In this study, all three cameras produced equally reliable measurements. Actual facial measurements were comparable to the photogrammetric measurements obtained from photographs taken using the MirS. A constant formula was derived; it allowed the conversion of photographic values into real anthropometric values. The MirS produced consistent photographs with respect to the measurements. The photographs obtained could be translated reliably into their real anthropometric measurements. Therefore, the MirS can be applied in daily practice, providing an efficient alternative for obtaining a standard justifiable photograph.