• Title/Summary/Keyword: MED

Search Result 2,778, Processing Time 0.028 seconds

Metastatic Hepatocellular Carcinoma of Spleen in a Holstein Cow

  • Jeong, Won-il;Son, Sung-bong;Jeong, Da-hee;Noh, Dong-hyung;Do, Sun-hee;Lee, Gi-ppeum;Yun, Hae-sun;Kwon, Oh-deok;Jeong, Kyu-shik
    • Proceedings of the Korean Society of Veterinary Pathology Conference
    • /
    • 2003.10a
    • /
    • pp.51-51
    • /
    • 2003
  • Hepatocellular carcinoma (HCC) is major type of cancer causing deaths on worldwide and has been reported in numerous species, including dogs, cats, sheep, pigs, fowl, woodchucks, trout and cows. The precise incidence data or complete age distribution of cattle is not known because this information was derived from abattoir. Moreover, there are very few reports in bovine HCC [l]. This report presents findings of bovine HCC with metastasis to the spleen, a very rare tumor in ruminant oncology, found in a Holstein cow during routine inspection at the abattoir. (omitted)

  • PDF

Research Progress on the Livin Gene and Osteosarcomas

  • Li, Cheng-Jun;Cong, Yu;Liu, Xiao-Zhou;Zhou, Xing;Shi, Xin;Wu, Su-Jia;Zhou, Guang-Xin;Lu, Meng
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.20
    • /
    • pp.8577-8579
    • /
    • 2014
  • Osteosarcoma is a common malignant tumor of bone, but mechanisms underlying its development are still unclear. At present, it is believed that the inhibition of normal apoptotic mechanisms is one of the reasons for the development of tumors, so specific stimulation of tumor cell apoptosis can be considered as an important therapeutic method. Livin, as a member of the newly discovered inhibitor of apoptosis proteins (IAPs) family, has specifically high expression in tumor tissues and can inhibit tumor cell apoptosis through multiple ways, which can become a new target for malignant tumor treatment (including osteosarcoma) and might of great significance in the clinical diagnosis of tumors and the screening of anti-tumor agents and carcinoma treatment.

Study on the Need for Distinction Between "Award by Consent" and "Med-Arb" (중재절차 중 '화해의 유도'와 '조정-중재'제도의 구분 필요성에 대한 연구)

  • Do, Hyejeong
    • Journal of Arbitration Studies
    • /
    • v.30 no.4
    • /
    • pp.51-70
    • /
    • 2020
  • The Mediation-Arbitration hybrid is becoming more popular since it makes an amicable relationship and thorough statement possible. The Mediation-Arbitration hybrid has been used to take advantage of both dispute resolution methods. In a Med-Arb process, negotiating a resolution to disputes is attempted with a mediator's help. If the mediation ends in an impasse or issues remain unresolved, parties can move on to arbitration. Med-Arb can also be cost-effective when disputants hire one person to serve as mediator and arbitrator (Med-Arb-Pure). However, it can disturb the fairness and neutrality of arbitrators, and awards can be annulled. Indeed, "Award by Consent" is different from the "Med-Arb-Pure" process. Arbitrators easily confuse them. Only the parties settle on the arbitral proceedings' course, and the arbitrator can help them (award by consent). The role and skill of a mediator are different from an arbitrator's. Disputants have the right to use a mediator who specializes in mediation. Moreover, mediation communication confidentiality is the essential value of mediation, and this should be protected. Therefore, in the process of "Med-Arb," separation between mediating and arbitrating is a better choice to specialize in each expertise. In this process, "Med-Arb" can be an affordable, expeditious, proper, and effective method of resolving international commercial disputes and continuing ADR prime time.

Early Detection of Bone Metastasis in Malignancy With whole Body Bone Scan (전신골격주사(全身骨格走査)를 이용(利用)한 골전이(骨轉移)의 조기발견(早期發見))

  • Kim, Myung-Duk;Jung, Soon-Il;Choi, Kang-Won;Kim, Byung-Kuk;Koh, Chung-Soon
    • The Korean Journal of Nuclear Medicine
    • /
    • v.13 no.1_2
    • /
    • pp.45-53
    • /
    • 1979
  • Bone scans with $^{99m}Tc$-MDP (methylene diphosphonate) was analysed in 112 patients with various type of biopsy proven malignant tumor who visited Seoul National University Hospital from March 1979 to August 1979. The results were as follows; 1. Of the 112 cases, bone scans were positive in 61 cases (54.1%), while only 27 cases (24.1%) were positive in roentgenogram. 2. Of the 61 cases with positive bone scan, bone metastases were found in 25 cases by roentgenogram. Of the 51 cases with negative bone scan, bone metastasis was found in only 1 case by roentgenogram. 3. In comparison of bone scan and roentgenogram by number of regions, 137 regions were positive in bone scan or roentgenogram. Of these, 46 regions (33.5%) were both bone scan and roentgenogram positive, 89 regions (65.0%) were bone scan positive roentgenogram negative, and 2 regions were bone scan negative roentgenogram positive. 4. Bone scan and roentgenographic findings had significant correlation with the presence of bone pain but no significant correlation with the elevated level of serum alkaline phosphatase, acid phosphatase, Ca, and P. From above result, we found that bone scan was more sensitive than roentgenogram in early detection of bone metastasis in malignant tumors.

  • PDF

A Study on the Depaminergic Control of T.S.H. Secretion (갑상선자극(甲狀腺刺戟) 호르몬 분비(分泌)에 대(對)한 Dopaminergic Contrl에 관(關)한 연구(硏究))

  • Kim, Myung-Duk;Lee, Jung-Sang;Koh, Chang-Soon;Lee, Mun-Ho;Kim, Eung-Jin
    • The Korean Journal of Nuclear Medicine
    • /
    • v.12 no.2
    • /
    • pp.7-16
    • /
    • 1978
  • To elucidate the depaminergic control of T.S.H. secretion, we analized the pattern of T.S.H. secretion in seven normal controls and nine primary hypothyroid subjects, before and after single or combined administration of specific dopaminergic,receptor blocker, metoclopramide, and specific depaminergic receptor stimulant, bromergocryptine(CB-154). The results obtained were as follows: 1) There was a significant rise in T.S.H. levels after intra venous injection of metocloramide (10mg) in hypothyroid subjects. But there was no significant rise in T.S.H. levels in normal controls. The T.S.H. response to metoclopramide varied considerably, being large in mild cases and small in severely hypothyroid subjects. 2) There was a significant fall in T.S.H. levels after oral administration of bromergocryptine (2mg) in hypothyroid subjects, but there was no significant fall in T.S.H. levels in normal controls. 3) There was no significant fluctuation in T.S.H. levels after combined administration of both metoclopramide and bromergocrytine. 4) There was no significant fluctuation in T.S.H. levels after intravenous injection of normal saline(2ml) in both hypothyroid and normal subjects. 5) There was no significant change in serum $T_3\;and\;T_4$ after administration of metoclopramide and and bromergocryptine respectively and serially. These data support the fact that there is a dopaminergic control in the secretion of T.S.H. in the human.

  • PDF

Inhibitory Effect of PME88 MelonSOD on the Ultraviolet-Induced Photo-aging (PME88 멜론SOD의 자외선으로 인한 피부 광노화 억제 효과)

  • Cho, Se-Haeng
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.38 no.4
    • /
    • pp.401-408
    • /
    • 2009
  • PME88 (gliadin-combined) melon superoxide dismutase (SOD) is known to promote the production of the body‘s own natural antioxidants including superoxide dismutase, catalase and glutathione peroxidase. In this study, we investigated the inhibitory effects of PME88 melonSOD on the ultraviolet-induced photo-aging by the evolution of minimal erythemal dose (MED), erythema quotation and spectrocolorimetric measurements of erythema. The analysis of the evolution of the MED showed a significant increase 28 days after the daily taken of the PME88 melonSOD. The analysis of the erythema quotation showed that on D29, for the dose 1.25 MED, erythema intensity is significantly higher for placebo group than for PME88 melonSOD group. At doses 0.64 MED$_{D14}$, 0.80 MED$_{D14}$ and 1 MED$_{D14}$ the value of parameter $a^*$ (the most sensitive to the colour changes bound to the variations of blood flow. It permits to assess the evolution of erythema) is significantly higher for placebo group. No significant difference has been observed between groups (PME88 melonSOD and placebo) on the evolution of the number and consistency of feces after 4 weeks of treatment. No intolerance has been observed during the 4 weeks of treatment. These results mean that PME88 melonSOD as a dietary supplement could be useful to attenuate ultraviolet-induced skin photo-aging.