• Title/Summary/Keyword: ME가

Search Result 6,192, Processing Time 0.034 seconds

ON THE GEOMETRY OF THE MANIFOLD MEX2n

  • Yoo, Ki-Jo
    • Bulletin of the Korean Mathematical Society
    • /
    • v.40 no.3
    • /
    • pp.475-487
    • /
    • 2003
  • A generalized even-dimensional Riemannian manifold defined by the ME-connection which is both Einstein and of the form (3.3) is called an even-dimensional ME-manifold and we denote it by $MEX_{2n}$. The purpose of this paper is to study a necessary and sufficient condition that there is an ME-connection, to derive the useful properties of some tensors, and to investigate a representation of the ME-vector in $MEX_{2n}$.

ON THE *g-ME-CONNECTION AND THE *g-ME-VECTOR IN *g-MEXn

  • Yoo, Ki-Jo
    • Honam Mathematical Journal
    • /
    • v.30 no.4
    • /
    • pp.603-616
    • /
    • 2008
  • A generalized n-dimensional Riemannian manifold $X_n$ on which the differential geometric structure is imposed by the unified field tensor $^*g^{{\lambda}{\nu}}$, satisfying certain conditions, through the $^*g$-ME-connection which is both Einstein's equation and of the form(3.1) is called $^*g$-ME-manifold and we denote it by $^*g-MEX_n$. In this paper, we prove a necessary and sufficient condition for the existence of $^*g$-ME-connection and derive a surveyable tensorial representation of the $^*g$-ME-connection and the $^*g$-ME-vector in $^*g-MEX_n$.

Apoptosis Inducing Effects of 6-Methoxydihydrosanguinarine in HT29 Colon Carcinoma Cells

  • Lee, Yong-Jin;Yin, Hu-Quan;Kim, Young-Ho;Li, Guang-Yong;Lee , Byung-Hoon
    • Archives of Pharmacal Research
    • /
    • v.27 no.12
    • /
    • pp.1253-1257
    • /
    • 2004
  • 6-Methoxydihydrosanguinarine (6ME), a benzophenanthridine alkaloid derived from the methanol extracts of Hylomecon hylomeconoides, showed a dose-dependent effect at 1-10 ${\mu}M$ on causing apoptotic cell death in HT29 colon carcinoma cells $(IC_{50} = 5.0{\pm}0.2 {\mu}M)$. Treatment of HT-29 cells with 6ME resulted in the formation of internucleosomal DNA fragmentation. Treatment of the cells with 6ME caused activation of caspase-3, -8 and 9 protease and subsequent proteolytic cleavage of poly(ADP-ribose)polymerase. 6ME increased the expression of p53 and Bax and decreased the expression of Bid. These results indicate that p53 and proapoptotic Bcl-2 family proteins might participate in the antiproliferative activity of 6ME in HT29 cells.

Anti-lipid Peroxidative Effect of Extracts and its Fractions Polygonatum odoratum (둥굴레 추출물 및 분획의 과산화지질 생성 저해효과)

  • 김주향;양기숙
    • YAKHAK HOEJI
    • /
    • v.46 no.4
    • /
    • pp.242-246
    • /
    • 2002
  • The rhizoma of Polygonatum odoratum (Liliaceae) promotes the production of body fluid and relives dryness symptoms and has hypoglycemic effect. In order to evaluate the prevention of lipid peroxidative efficacy of P. odoratum, its extracts (Et$_2$O and MeOH ex.) and its fractions ($H_2O$, 20% MeOH, 40% MeOH, 60% MeOH and 100% MeOH fr.) were measured by TBARS assay on rat liver S9 and human erythrocyte ghost membrane. The order of anti-lipid peroxidative effect was as follows: Et$_2$O ex. >40% MeOH fr. >60% MeOH fr.>100% MeOH fr. Based on these results, we conclude that membrane lipid peroxidation is inhibited in vitro by addition of P. odoratum ether extract and its gradient MeOH fractions excepts $H_2O$ fr., and which have significant hepatoprotective activity in $CCl_4$-treated rats.

Comparison of Key Words of the Journal of Korean Academy of Fundamentals of Nursing with MeSH (2003-2007) (기본간호학회지 게재 논문의 주요어와 MeSH 용어의 비교(2003-2007년))

  • Chaung, Seung-Kyo;Sohng, Kyeong-Yae;Kim, Kyung-Hee
    • Journal of Korean Academy of Fundamentals of Nursing
    • /
    • v.15 no.4
    • /
    • pp.558-565
    • /
    • 2008
  • Purpose: The purpose of this study was to analyze how accurately authors of the Journal of Korean Academy of Fundamentals of Nursing used MeSH terms as key words. Method: A total of 724 key words used in the 225 papers of Journal of Korean Academy of Fundamentals of Nursing from 2003 to 2007 were compared with MeSH terms. Results: Fifty nine point eight percent of total key words were completely coincident with MeSH terms, 13.5% were entry terms, and 21.8% were not MeSH terms. The coincidence rates for 2003 and 2007 separately were 38.5% and 70.9%. Also, 25.3% of papers precisely used MeSH terms as key words and 8% did not use any MeSH terms. Conclusion: The results show that the coincidence rate of key words with MeSH terms was at a moderate level and gradually increased according to year. However, there is a need for us to understand MeSH more specifically and accurately.

  • PDF

Changes on the Methylmercury-induced Cytotoxicity by Control of Cell Membrane Transport System (세포막 물질수송계의 조절에 의한 유기수은의 세포독성 변화에 대한 연구)

  • 염정호;고대하;김준연;김남송
    • Journal of Environmental Health Sciences
    • /
    • v.26 no.4
    • /
    • pp.88-96
    • /
    • 2000
  • The aim of the current study was to evaluate the transport system in EMT-6 cell for the uptake of the methylmercury(MeHg). Several inhibitors ere used to test used to test which potential transport system might be involoved in MeHg uptake. Probenecid was used to test the organic transport system, valinomycin for testing the effect of the membrane potential, cytochalasin B for testing the facilitated diffusive D-glucose transport system and colchicine for testing the microtubule system. Ouabain for evaluating active transport system, 4',4-diisothiocyano-2',2-stilbenedisulfonic acid(DIDS) the Cl- ion transport system and verapamil for the $Ca^{2+}$ transprot system. Significantly, MeHg decreased the synthesis of nitric oxcide(NO) and intracellular ATP in ENT-6 cells. In the condition of ouabain containing with MeHg decreased the production of NO and intracelluar ATP. In the treatment of inhibitors, ouabain showed protective effect against cytotoxicity of MeHg but ather inhibitors not showed protective effects. The protective effects of ouabain against the cytotoxicity of MeHg deoended on the concentration of added ouabain to the culture medium for MET-6 cells. These result showed that the uptake of MeHg might be involved in the active transport system. Active transports system seems to share similarities with the transport systems for the uptake of MeHg when using MeHg and MeHg-glutathione complex.x.

  • PDF

Synthesis and Characterization of Dinuclear Mo(Ⅲ) and V(Ⅲ) Complexes (Ⅴ) (몰리브덴(Ⅲ)과 바나듐(Ⅲ) 이핵 착물의 합성과 특성 (제5보))

  • Oh, Sang-Oh;Lyou, Eun-Young
    • Journal of the Korean Chemical Society
    • /
    • v.39 no.7
    • /
    • pp.530-537
    • /
    • 1995
  • The neutral complexes $MCl_3(phda)(MeCN)]$ and $[MCl_3(PPh_3)_2(MeCN)]$ (M=Mo, V) were prepared by the reaction of $MCl_z$, (M=Mo; z=5, M=V; z=3) with N, P-donating ligands in acetonitrile solution. Addition of AgClO_4$ to these neutral monomeric complexes in acetone solution afforded $MCl_{3-n}L_2(MeCN)(S)_n](ClO_4)_n$ (n=1, 2 : s=solvent). Two types of asymmetrical homo- and hetero-dinuclear complexes have been synthesized. The type of chloride bridged dinuclear complex is $[(MeCN)(phda)ClM({\mu}-Cl)_2M'Cl(PPh_3)_2(MeCN)](ClO_4)_2.$ And the type of pyrazine bridged complex is $[(MeCN)(phda)Cl_2M({\mu}-pyz)M'Cl_2(PPh_3)_2(MeCN)](ClO_4)_2.$ These complexes were characterized by elemental analysis, $^1H,\;^13C$ NMR, IR, Far-IR and UV-Vis spectroscopy.

  • PDF

Solvation in Mixed Solvents (VII). Solvolysis of t-Butyl Halide in Isodielectric Solvents (혼합용매에서의 용매화 (제 7 보). 등유전상수 용매에서 t-Butyl Halide 의 가용매분해반응)

  • Lee, Ick-Choon;Lee, Hai-Whang;Uhm, Tae-Seop;Sung, Dae-Dong;Ryu, Zoon-Ha
    • Journal of the Korean Chemical Society
    • /
    • v.32 no.2
    • /
    • pp.85-93
    • /
    • 1988
  • Solvolyses of t-butylhalides (X = Cl, Br, I) in quasi isodielectric solvent system, MeOH-nitromethane, MeOH-nitrobenzene and MeOH-ethyleneglycol have been studied kinetically. Methanolyses for t-butylhalides in MeOH-NM and MeOH-NB show rate maxima at 40~100 % (v/v) MeOH. The rate maxima observed have been interpreted as a result of cooperative enhancement of polarity-polarizability and hydrogen bonddonor ability of solvents. The influences of polarity-polarizability and hydrogen bonddonor ability on reactivities of substrates have been discussed in terms of Y value changes. The solvolysis rates for t-butylhalides in E.G. are more than 20 fold faster than those in MeOH and this was attributed to the solvent structure of E.G.

  • PDF

A Study on Quality Characteristics of Kimchi with added Mulberry Leaves Extracts (뽕잎 추출액 첨가 김치의 품질 특성에 관한 연구)

  • Lee, Young-Sook;Rho, Jeong-Ok
    • Journal of the East Asian Society of Dietary Life
    • /
    • v.24 no.6
    • /
    • pp.827-836
    • /
    • 2014
  • In this study, the effects of Mulberry leaves extract (ME) addition on the quality of Kimchi was investigated during 30 days of fermentation at $5^{\circ}C$. ME was added to salted cabbage at concentrations of 0% (C), 0.4% (ME1), 0.8% (ME2) and 1.2% (ME3) (w/w). The pH of Kimchi added above 0.8% ME was higher than that of Kimchi without ME after 12 days of fermentation. During overall fermentation, the titratable acidity of Kimchi with 1.2% ME remained at the lowest level. The degree of salinity decreased with increasing amount of added ME, whereas control groups showed the highest salinity. In L, a and b values of samples, the highest Figures of L and b were observed in control groups, and ME3 showed the highest value of a. In addition, the cutting force during the fermentation period was higher in all treated groups compared with control groups, and ME3 showed the highest hardness value. Moreover, growth of lactic acid bacteria and total bacteria were inhibited by addition of ME. In the sensory assessment, 0.4% ME improved the quality of Kimchi, showing the highest taste score and overall preference. Therefore, addition of 0.4% ME appears to be an acceptable approach to enhance the quality of Kimchi without reduction of acceptability.

Antioxidative Effects of Mugwort (Artemisia vulgaris L.) Extracts Diet on ICR Mouse Skin (애엽 추출물 섭취가 ICR 마우스의 피부조직에 미치는 항산화 효과)

  • Park, Si-Hyang;Cho, Duck-Moon;Choi, Gyeong-Lim;Choi, Yeung-Joon;Choi, Jin-Ho
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.36 no.12
    • /
    • pp.1523-1528
    • /
    • 2007
  • The feeding effects of mugwort (Artemisia vulgaris L.) extracts (ME) on the anti-oxidative actions of ICR mouse skin was investigated. To study the antioxidative effects of ME on ICR mouse skin, female ICR mice were grouped into basic diet group (control), ascorbic acid diet group (AA-2.5, AA-5.0, AA-10.0 and AA-20.0 mg/kg BW/day) as a positive control and experimental diet group (mugwort extract; ME-25, ME-50, ME-100, and ME-200 mg/kg BW/day) and fed for 10 weeks. Protein contents in ME-50, ME-100, and ME-200 feeding group were increased ($3.1%{\sim}11.1%$) and hydroxyl radical contents were significantly decreased ($10.4%{\sim}17.4%$) compared to control group. Oxidative stress signals and oxidized protein contents were significantly reduced to the range of 15.3 to 17.1% in ME-100 and ME-200 groups. Also, superoxide dismutase (SOD) activity was significantly increased to the range of 15.0% to 23.3% in ME-100 and ME-200 groups. Catalase activities were significantly increased ($14.0%{\sim}36.9%$) in all groups in a dose-dependent pattern. Antioxidative ability of ME showed similarity to that of ascorbic acid.