• Journal of the Korea Institute of Information Security & Cryptology
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• v.19 no.2
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• pp.63-74
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• 2009

In 2005, Wang et al. discovered devastating collision attacks on the main hash functions from the MD4 family. After the discovery of Wang, many analysis results on the security of existing hash-based cryptographic schemes are presented. At CRYPTO'07, Fouque, Leurent and Nguyen presented full key-recovery attacks on HMAC/NMAC-MD4 and NMAC-MD5[4]. Such attacks are based on collision attacks on the underlying hash function, and the most expensive stage is the recovery of the outer key. At EUROCRYPT'08, Wang, Ohta and Kunihiro presented improved outer key recovery attack on HMAC/NMAC-MD4, by using a new near collision path with a high probability[2]. This improves the complexity of the full key-recovery attack on HMAC/NMAC-MD4 which proposed by Fouque, Leurent and Nguyen at CRYPTO'07: The MAC queries decreases from $2^{88}$ to $2^{72}$, and the number of MD4 computations decreases from $2^{95}$ to $2^{77}$. In this paper, we propose improved outer key-recovery attack on HMAC/NMAC-MD4 with $2^{77.1246}$ MAC queries and $2^{37}$ MD4 computations, by using divide and conquer paradigm.

• Journal of Korea Multimedia Society
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• v.6 no.2
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• pp.194-207
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• 2003

This paper presents an optimal design methodology for the multidimensional nested attribute index (MD-NAI) that uses a multidimensional index structure for indexing the nested attributes in object databases. The MD-NAI efficiently supports complex queries involving both nested attributes and class hierarchies, which are not supported by the nested attribute index using one-dimensional index structure such as $B^+$-tree. However, the performance of the MD-NAI is very degraded in some cases of user's query types. In this paper, for the performance enhancement of the MD-NAI, we first determine the optimal shape of index page region by using the query information about the nested predicates, and then construct an optimal MD NAI by applying a region splitting strategy that makes the shape of the page regions of the MD-NAI as close as possible to the predetermined optimal one. For performance evaluation, we perform extensive experiments with the MD-NAI using various types of nested predicates and object distribution. The results indicate that our proposed method builds optimal MD-NAI regardless of the query types and object distributions. When the interval ratio of a three-dimensional query region is 1:16:236, the performance of the proposed method is enhanced by as much as 5.5 times over that of the conventional method employing the cyclic splitting strategy.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.16 no.5
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• pp.1015-1022
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• 2012

This paper deals with hardware design which unifies MD5 and HAS-160 hash algorithms. Two algorithms get a message with arbitrary length and process message blocks divided into 512 bits each time and output a hash code with a fixed length. MD5 ouputs a hash code of 128 bits and HAS-160 a hash code of 160 bits. The unified hash core designed has 32% of slices overhead compared to HAS-160 core. However, there is only a fixed message buffer space used. The unified hash core which run a step in one clock cycle operates at 92MHz and has performance which digests a message in the speed of 724Mbps at MD5 and 581Mbps at HAS-160 hash mode. The unified hash core which is designed can be applicable to the areas such as E-commerce, data integrity and digital signature.

• Korean Journal of Human Ecology
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• v.24 no.3
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• pp.437-449
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• 2015

The purpose of this study was to investigate the quality characteristics of Dangmyon(starch vermicelli) prepared with mulberry leaves powder. Mulberry leaves powder was added in ratios (w/w) of 0% (CON), 0.5% (MD1), 1.0% (MD2), 1.5% (MD3). and 2.0%(MD4), and then proximate compositions, physicochemical properties, RVA, SEM, texture and sensory evaluations of the Dangmyon were measured. MD1~MD4 samples showed higher contents of moisture, crude lipid, crude protein and crude ash as well as pH compared to control (p<0.001). In terms of color, lightness (L), yellowness (b), and redness (a) decreased as the mulberry leaves powder increased. The results of RVA properties analysis on all samples showed that control had the highest. With regard to the texture of Dangmyon samples, the scores of hardness, adhesiceness, gumminess, chewiness, resilience of CON was significantly higher than the samples MD1~MD4 (p<0.001), but the scores of springiness, cohesiveness was not significantly among samples. The result of observation on the cross section of Dangmyon added with mulberry leaves powder showed that number, size of cavity more increase compared to the control. In sensory evaluation, the scores of appearance, flavor, taste and overall preference for MD3 were significantly higher than the samples (CON, MD1, MD2, and MD4). From the findings, this study suggests that 1.5% addition of mulberry leaves powder was effective for preparation of Dangmyon in the aspects of the consumer acceptability.

• Journal of Distribution Science
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• v.3 no.1
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• pp.43-67
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• 2005

Recently retail market has been rapidly expanded in the large cities of in Korea and the competition among individual companies in retail market is also being increased. Tenant MD of mixing is one of the most important factor for the company to continuously operate or to fail. The aim of this study is to examine the processes of systematically evaluating the merchandising of the established companies in retail market a part of chain operation in discount store. The basic problem of decision making in general and tenant MD of mixing in particular is to choose a best one in a set of competing alternatives that are evaluated under conflicting criteria. The purpose of research of a paper carries out a duty searching examination with making a tenant MD include by retail research, simultaneously defined when I will show an example for the tenant mix of the profitability side of the domestic discount store market which is tenant MD importance proposing the existing problem arrangement by chain operation management, and is intensifying - tenant MD of standardization in discount store of T-company.

• Journal of Dairy Science and Biotechnology
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• v.32 no.2
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• pp.163-167
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• 2014

This study aimed to investigate the anti-obesity effects of Enterococcus faecalis MD366, isolated from raw milk, in diet-induced obese mice. To examine the effect, male C57BL/6J mice were fed for six weeks on three different diets, i.e., a normal diet and orally administrated saline solution (ND), a high-fat diet and orally administrated saline solution (HFD), and a high-fat diet and orally administrated E. faecalis MD366 ($10^9CFU/day$) in saline solution (HFD+MD366). After six weeks, the rate of increase in body weight was 18.1% lower in the HFD+MD366 group compared to that in the HFD group. In addition, the weight of epididymal fat pad in the HFD+MD366 group was lower than that in the HFD group. The average levels of triglycerides, total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C) were slightly reduced in the HFD+MD366 group compared to those in the HFD group. However, there were no significant differences between the groups. Measuring the adipocytes revealed that the percentage of adipocytes with a size of $2,000{\mu}m^2$ was higher than the percentages of other size classes in ND and HFD+MD366 groups, while the percentage of adipocytes larger than $5,000{\mu}m^2$ was highest in the HFD group. The mean adipocyte size in the HFD+MD366 group was smaller than that in the HFD group.

• Advances in pediatric surgery
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• v.1 no.1
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• pp.33-39
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• 1995

The incidence of Meckel's diverticulum(MD) in general population has been assessed as 2 percent. The major complications of MD are bleeding, perforation, and intestinal obstruction. In spite that the complication rate of Meckel's diverticulum is relatively high(about 4.2% during a lifetime), the preoperative diagnostic rate of complicated MD is very low. Authors investigated the clinical characteristics of complicated MD to improve the diagnostic rate. 16 patients with complicated Meckel's diverticulum who were operated upon at the Department of Pediatric Surgery, Seoul National University Children's Hospital from June 1985 to December 1993 were reviewed. Among the 16 patients with complicated MD, 12 patients(75%) were under 2 year-old and male were predominant(88%). The most common complication was bleeding patients with bleeding MD (8 cases) were diagnosed preoperatively as MD. 8 patients with other complications(perforation : 4 cases, obstruction : 4 cases) could not be suspected as complicated MD except one patient who had previous history of melena. These patients were diagnosed after exploratory laparotomy under the various impression other than MD. Among 12 patients with ulcer related complications such as bleeding and perforation, heterotopic gastric mucosa was found in 11 patients. In conclusion, in any children with unexplained acute abdomen, especially under 2 years old, complicated MD must be included in differential diagnosis. In children with obscure lower gastrointestinal bleeding, $^{99m}Tc$-pertechnetate scintigraphy is a useful diagnostic tool to rule out bleeding MD.

• Proceedings of the IEEK Conference
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• 2002.06b
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• pp.117-120
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• 2002

In this paper, we construct cryptographic accelerators using hardware Implementations of HMACS based on a hash algorithm such as MD5.It is basically a secure version of his previous algorithm, MD4 which is a little faster than MD5 The algorithm takes as Input a message of arbitrary length and produces as output a 128-blt message digest The input is processed In 512-bit blocks In this paper, new architectures, Iterative and full loop, of MD5 have been implemented using Field Programmable Gate Arrays(FPGAS). For the full-loop design, the performance Is about 500Mbps @ 100MHz

• Bulletin of the Korean Mathematical Society
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• v.30 no.2
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• pp.265-275
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• 1993

In this paper, we study the monotonicity of the Dittert function (abb. MD) on the line segment from A .mem. $K_{n}$ to J$_{n}$ generalizing both the Dittert conjecture and the Monotonicity conjecture for permanent, and obtain a sufficient condition on A .mem. $K_{n}$ for which the MD holds. It is also proved that if A .mem. $K_{n}$ satisfies the Dokovic inequality (1.2) then MD holds for A, and a subclass of $K_{n}$ for which MD holds is found. is found.

• BMB Reports
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• v.50 no.2
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• pp.55-57
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• 2017

Toll-like receptor 4 (TLR4) together with MD2, one of the key pattern recognition receptors for a pathogen-associated molecular pattern, activates innate immunity by recognizing lipopolysaccharide (LPS) of Gram-negative bacteria. Although LBP and CD14 catalyze LPS transfer to the TLR4/MD2 complex, the detail mechanisms underlying this dynamic LPS transfer remain elusive. Using negative-stain electron microscopy, we visualized the dynamic intermediate complexes during LPS transfer-LBP/LPS micelles and ternary CD14/LBP/LPS micelle complexes. We also reconstituted the entire cascade of LPS transfer to TLR4/MD2 in a total internal reflection fluorescence (TIRF) microscope for a single molecule fluorescence analysis. These analyses reveal longitudinal LBP binding to the surface of LPS micelles and multi-round binding/unbinding of CD14 to single LBP/LPS micelles via key charged residues on LBP and CD14. Finally, we reveal that a single LPS molecule bound to CD14 is transferred to TLR4/MD2 in a TLR4-dependent manner. These discoveries, which clarify the molecular mechanism of dynamic LPS transfer to TLR4/MD2 via LBP and CD14, provide novel insights into the initiation of innate immune responses.