• Title/Summary/Keyword: MCT

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Growth Performance, Plasma Fatty Acids, Villous Height and Crypt Depth of Preweaning Piglets Fed with Medium Chain Triacylglycerol

  • Chwen, Loh Teck;Foo, Hooi Ling;Thanh, Nguyen Tien;Choe, D.W.
    • Asian-Australasian Journal of Animal Sciences
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    • v.26 no.5
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    • pp.700-704
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    • 2013
  • A study was conducted to investigate the effects of feeding medium chain triacylglycerol (MCT) on growth performance, plasma fatty acids, villus height and crypt depth in preweaning piglets. A total of 150 new born piglets were randomly assigned into one of three treatments: i) Control (no MCT); ii) MCT with milk (MCT+milk); iii) MCT without milk (MCT+fasting). Body weight, plasma fatty acid profiles, villus height and crypt depth were measured. Final BW for the Control and MCT+fasting was lower (p<0.05) than MCT+milk. The piglets fed with MCT regardless of milk provision or fasting had greater medium chain fatty acids (MCFA) than the Control. In contrast, the Control had greater long chain fatty acid (LCFA) and unsaturated fatty acid (USFA) than the MCT piglets. The piglets fed with MCT regardless of milk provision or fasting had higher villus height for the duodenum and jejunum after 6 h of feeding. Similar observations were found in piglets fed with MCT after 6 and 8 days of treatment. This study showed that feeding MCT to the piglets before weaning improved growth performance, with a greater concentration of MCT in blood plasma as energy source and a greater height of villus in duodenum, jejunum and ileum.

The Study on the Quality Characteristics of Cake Prepared with Fat Substitute (대체지방으로 제조한 케이크의 품질 특성에 관한 연구)

  • Woo, Na-Ri-Yah;Ahn, Myung-Soo
    • Journal of the Korean Society of Food Culture
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    • v.19 no.5
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    • pp.506-515
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    • 2004
  • This study was carried on the quality characteristics of cake prepared with Co(com oil) containing MCT(medium chain triglycerides), which is used as a fat substitute. In tile cake prepared with MCT-CO containing $10{\sim}30%$ MCT, the appearance and the degree of gelatinization were similar to those of cake prepared with NS-CO(non-substituted corn ell) Cake batter prepared with MCT-CO showed higher specific gravity and consistency than those of cake prepared with NS-CO and increased by increasing MCT contents. The baking loss of cake prepared with MCT-CO was more than that of cake prepared with NS-CO and increased by increasing MCT contents as well. The rheological properties of cake represented significant different by MCT substitution ratio(p<0.05). Gumminess, hardness and chewiness of cake prepared with MCT-CO containing $20{\sim}30%$ MCT were about 2 times higher than those of cake prepared with NS-CO, while springiness and cohesiveness showed similar pattern between the cake prepared with MCT-CO or NS-CO. In sensory evaluation, appearance. color and flavor of cake prepared with CO substituted by MCT up to 100% were better assessed and the taste was better in range of 30% MCT-CO but the texture was less accepted than that of cake prepared with NS-CO.

A Study on the Oxidative Stability and Cooking Scientific Characteristics of Fat Substitute MCT (MCT 대체지방의 산화안정성 및 조리 적합성에 관한 연구)

  • Ahn, Myung-Soo;Woo, Na-Ri-Yah
    • Journal of the Korean Society of Food Culture
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    • v.18 no.2
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    • pp.181-191
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    • 2003
  • This study was carried on the oxidative stability and the real practice possibilities in cooking of fat replacer MCT. Nowadays, it was known that fats and oils had become causes for cardiac disease, obesity and cancer, so the new materials were needed for fat substitute that has less fat contents and low calories. The food industry concerned about fats and oils had been researched and developed new and various kinds of substitute fats. MCT(medium chain triglycerides) is one of the fat based fat substitutes used as fat replacers. The POV of com germ oil(CO), soybean oil(SO), shortening(ST), butter(BT), their blended oil with MCT 10-50%(w/w), and MCT were determined and oxidative stability by POV was compared MCT with those of them. MCT has shown higher oxidative stability than CO, SO, ST, BT, so oxidative stabilities in all kinds of blended oils become higher and higher by the increased substitution ratios. In case of bread, the volume of bread prepared with MCT(MCT bread) substituted for ST at 10-40% level(w/w) were increased a little comparing to that made of shortening(ST bread). But degree of gelatinization of MCT bread were a little lower than ST bread, at the substitute ratio above 40%, the degree of gelatinization were reduced greatly. These phenomena were sustained in 9 stored days. While baking losses of MCT breads were almost same as ST bread until 30% substitute ratio, and the appearances of MCT breads were similar to ST bread until 40% substitute ratio. Also rheological properties and color(Lab) of MCT breads had shown no different significantly from ST bread until 20% substitute ratio, but by the results of sensory evaluation, overall acceptance including appearance, color, flavor, taste, texture of MCT breads were recognized almost same as ST bread by panel until 40% substitute ratio. Depends on the above results, we can suggest that 30-40% of MCT will substitute for shortening in making bread in order to reduce fat and calories intake amounts.

Postnatal Ontogeny of Expression of Monocarboxylate Transporters(MCTs) and Two Regulatory Proteins, Basigin and Embigin, in The Epididymis of Male Rat (흰쥐의 부정소에서 Monocarboxylate Transporters(MCTs)와 조절 단백질, Basigin과 Embigin의 생후 발달 과정 동안 발현 양상)

  • Lee, K.H.
    • Journal of Animal Science and Technology
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    • v.50 no.1
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    • pp.45-56
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    • 2008
  • In the present study, real-time PCR was performed to evaluated expression of several isoforms of monocarboxylate transporters(MCTs) and two known MCT regulatory proteins, basigin (Bsg) and embigin, in the epididymis of the male reproductive tract during postnatal development. In addition, ERα�-mediated regulation of MCT1 expression in the epididymis was determined with estrogen receptor(ER) α� knockout(α�ERKO) mice by immunohistochemistry. Results from the current study demonstrated differential expression of MCT isoform(MCT 1, 2, 3, 4, and 8), Bsg, and embigin mRNAs in rat epididymis according to postnatal age and epididymal region. In addition, immunohistochemical study of MCT1 revealed the limited localization of MCT1 at apical area of corpus and caudal epididymis. The present study also showed that expression of MCT1 was not directly regulated by ERα�. The findings from the current study suggest that MCTs would involve in establishing adequate microenvironment for sperm maturation and storage in the epididymis, eventually leading to maintenance of male fertility.

Realization of Multiple-Control Toffoli gate based on Mutiple-Valued Quantum Logic (다치양자논리에 의한 다중제어 Toffoli 게이트의 실현)

  • Park, Dong-Young
    • Journal of Advanced Navigation Technology
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    • v.16 no.1
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    • pp.62-69
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    • 2012
  • Multiple-control Toffoli(MCT) gates are macro-level multiple-valued gates needing quantum technology dependent primitive gates, and have been used in Galois Field sum-of-product (GFSOP) based synthesis of quantum logic circuit. Reversible logic is very important in quantum computing for low-power circuit design. This paper presents a reversible GF4 multiplier at first, and GF4 multiplier based quaternary MCT gate realization is also proposed. In the comparisons of MCT gate realization, we show the proposed MCT gate can reduce considerably primitive gates and delays in contrast to the composite one of the smaller MCT gates in proportion to the multiple-control input increase.

Expression of Monocarboxylate Transporters(MCTs) and Basigin and Estrogen Receptor α(ERα)-Mediated Regulation of MCT1 Expression in The Efferent Ductules of Male Reproductive Tract During Postnatal Development (생후 발달과정동안 남성 생식기의 Efferent Ductules에서 Monocarboxylate Transporters(MCTs)와 Basigin의 발현 양상과 에스트로젠 수용체 α에 의한 MCT1 발현 조절 연구)

  • Lee, Ki-Ho;Choi, I.H.;Chung, C.S.;Chang, J.S.
    • Journal of Animal Science and Technology
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    • v.49 no.3
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    • pp.309-320
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    • 2007
  • The purpose of the present study was to determine if monocarboxylate transporter(MCT) isoforms and Basigin(Bsg) are expressed in the efferent ductules(ED) and if MCT1 expression is under estrogen receptor(ER)α-regulation in the ED of male reproductive tract. The presence of MCT isoforms and Bsg mRNAs was detected by real-time polymerization chain reaction(PCR), and ERα-mediated regulation of MCT1 expression in the ED was indirectly determined by immuno- histochemistry. Current study found differential expression of MCT isoforms(MCT1, 2, 3, 4, and 8) and Bsg mRNAs in rat ED according to postnatal ages. In addition, comparison of MCT1 expression in the ED between wild type and ERα knockout mice at different postnatal ages showed basolateral localization of MCT1 in ciliated cells of the ED and, in part, ERα- mediated regulation of MCT1 expression. It is suggested that MCTs would play a role in regulation of function of the ED.

The Effect of Oral Administered Medium Chain Triglyceride Diet on the Serum Lipids and Enzyme Activities of Rats (MCT를 경구투여(經口投與)한 흰쥐의 혈중지질(血中脂質) 및 효소활성(酵素活性)에 미치는 영향(影響))

  • Cho, Chung-Soon;Jeong, Seung-Tai
    • Journal of the Korean Applied Science and Technology
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    • v.5 no.1
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    • pp.31-40
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    • 1988
  • The purpous of the study was to find an effect of oral administered medium chain triglyceride(MCT) diet on the serum and enzyme activities of Spraque-Dawly rats when they were oral fed with MCT, soybean oil and palm oil. The result was as follow. 1) The body weight gains in MCT diet group was lower than that of the all experimental group. 2) Total cholesterol levels in serum and liver of MCT diet group were very lower than that of the all experimental groups. 3) HDL-cholesterol level of MCT diet group was higher than that of the all experimental group except normal group and VLDL, LDL-cholesterol levels was very higher. 4) TG and PL levels of MCT diet group higher than that of the control group. 5) The activities of GOT with soybean oil diet group and of GPT with MCT diet group were lower than that of the all experimental group. 6) HDL-levels in the serum lipoprotein of MCT diet group was increased and LDL levels was decreased.

Hypoxic pulmonary vasoconstriction and vascular contractility in monocrotaline-induced pulmonary arterial hypertensive rats

  • Kim, Hae Jin;Yoo, Hae Young
    • The Korean Journal of Physiology and Pharmacology
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    • v.20 no.6
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    • pp.641-647
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    • 2016
  • Pulmonary arterial hypertension (PAH) is a progressive disease characterized by vascular remodeling of pulmonary arteries (PAs) and increased vascular resistance in the lung. Monocrotaline (MCT), a toxic alkaloid, is widely used for developing rat models of PAH caused by injury to pulmonary endothelial cells; however, characteristics of vascular functions in MCT-induced PAH vary and are not fully understood. Here, we investigated hypoxic pulmonary vasoconstriction (HPV) responses and effects of various vasoconstrictors with isolated/perfused lungs of MCT-induced PAH (PAH-MCT) rats. Using hematoxylin and eosin staining, we confirmed vascular remodeling (i.e., medial thickening of PA) and right ventricle hypertrophy in PAH-MCT rats. The basal pulmonary arterial pressure (PAP) and PAP increase by a raised flow rate (40 mL/min) were higher in the PAH-MCT than in the control rats. In addition, both high $K^+$ (40 mM KCl)- and angiotensin II-induced PAP increases were higher in the PAH-MCT than in the control rats. Surprisingly, application of a nitric oxide synthase inhibitor, L-$N^G$-Nitroarginine methyl ester (L-NAME), induced a marked PAP increase in the PAH-MCT rats, suggesting that endothelial functions were recovered in the three-week PAH-MCT rats. In addition, the medial thickening of the PA was similar to that in chronic hypoxia-induced PAH (PAH-CH) rats. However, the HPV response (i.e., PAP increased by acute hypoxia) was not affected in the MCT rats, whereas HPV disappeared in the PAH-CH rats. These results showed that vascular contractility and HPV remain robust in the MCT-induced PAH rat model with vascular remodeling.

Kernel Classification Using Data Distribution and Soft Decision MCT-Adaboost (데이터 분포와 연판정을 이용한 MCT-Adaboost 커널 분류기)

  • Kim, Kisang;Choi, Hyung-Il
    • KIPS Transactions on Software and Data Engineering
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    • v.6 no.3
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    • pp.149-154
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    • 2017
  • The MCT-Adaboost algorithm chooses an optimal set of features in each rounds. On each round, it chooses the best feature by calculate minimizing error rate using feature index and MCT kernel distribution. The involved process of weak classification executed by a hard decision. This decision occurs some problems when it chooses ambiguous kernel feature. In this paper, we propose the modified MCT-Adaboost classification using soft decision. The typical MCT-Adaboost assigns a same initial weights to each datum. This is because, they assume that all information of database is blind. We assign different initial weights with our propose new algorithm using some statistical properties of involved features. In experimental results, we confirm that our method shows better performance than the traditional one.

Effect of Medium Chain Triglyceride Diet on Cholesterol Metabolism of Serum and Liver in Rats (Medium Chain Triglyceride 및 유지(油脂) 첨가식이(添加食餌)를 투여(投與)한 흰쥐의 혈중(血中) 및 간장(肝臟) Cholesterol대사(代射)의 변동(變動))

  • Cha, Jae-Son;Michihiro, Sugano
    • Journal of the Korean Applied Science and Technology
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    • v.3 no.1
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    • pp.49-55
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    • 1986
  • The purpose of the study was to find an effect of Medium Chain Triglycerids (MCT) diet on cholesterol metabolism in rat. Sprague-Dawley rats were fed two different diets containing MCT(trioctanoate) and corn oil respectively. After feeding to each group for four weeks, the levels of serum and liver cholesterol, the excretion rates of fecal and biliary steroids, and also bile acid composition were investigated. The results obtained from the study are as follows : (1) The average body weight gain in MCT group was almost same as that in the corn oil group. (2) The concentration of serum cholesterol in MCT group was lower than that in the corn oil group. Therefore it is confirmed that the cholesterol lowing action of MCT diet was practically high. (3) The concentrations of liver cholesterol and Triglyceride in MCT group were almost same as that in the corn oil group. Therefore it is thought that the level of liver lipids was not influenced by the difference of diet in this study. (4) The excretion rate of fecal neutral steroid in MCT group was significantly lower than that in the corn oil group, while the rate of fecal bile acid excretion was about same in both MCT and corn oil group. (5) The composition rates of fecal bile acid such as cholic acid, chenodeoxycholic acid and deoxycholic acid, a secondary acid of cholic acid, in MCT group were significantly lower than that in the corn oil group. (6) The excretion rates of biliary cholesterol and bile acid in MCT group were significantly higher than that in the corn oil group, while the composition rates of biliary bile acid such as chenoddeoxycholic acid and deoxycholic acid in MCT group were significantly higher than that in the corn oil group.