• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2017.05a
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• pp.673-676
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• 2017

The Offshore drilling system of domestic drilling systems (drill rigs, drill ship) in Korea is dependent on full imports and the monopolistic situation of a few foreign large corporations is intensifying. In addition, most of domestic technology development tries to develop single product oriented products until now, but it is necessary to develop monitoring control system for package unit commercialization by approaching package development method. Therefore, we will develop a control monitoring system that can integrate the single equipment of the mud system developed previously.

• Journal of the Korean Society of Safety
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• v.36 no.4
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• pp.12-19
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• 2021

This paper presents a safety assessment method for FTA-based induction heating systems; the failures and causes of electrical fire are first analyzed for each part and module qualitatively, and methods to manage high probabilities of failure and electrical fire are considered, thereby improving the reliability of the induction heating system. The cumulative importance value (ACC) of the minimal cut set is drawn by setting failure as the top event, and STACK and SMPS are observed to account for about 70% of the induction heating system failures. Thus, intensively managing the basic events contained in the minimal cut set of failures for STACK and SMPS is expected to provide effective and stable operation of the induction heating system. When electrical fire is set as the top event, the STACK percentage is 90%. Accordingly, the current IGBT is changed to a FET to increase the applied voltage and prevent induction heating system failure, and a heat sink plane is installed to prevent FET heating caused by switching, thereby preventing an electrical fire. By classifying the parts and modules of the induction heating system in detail and by applying FTA based on actual failure rates and relevant data, more practical and reasonable results may be expected. Hence, continuous research must be conducted to ensure safety when using induction heating systems.

• Journal of Korea Water Resources Association
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• v.51 no.7
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• pp.543-554
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• 2018

A methodology has been presented for evaluating the partial safety factors on the sliding failure mode of vertical caissons of composite breakwaters and for determining the cross sections of those by Level I reliability-based design method. Especially, a mathematical model has been suggested for the sake of a consistency of code format as well as convenience of application in practical design, for which the uncertainties associated with buoyancy and its own weight can be taken into account straightforwardly. Furthermore, design criteria equation has been derived by considering accurately the effect of uplift pressure, so that the cross sections of caissons can be assessed which must be safe against the sliding failure. It has been found that cross sections estimated from partial safety factors proposed in this paper are in very good agreement with the results of Level II AFDA and Level III MCS under the same target probability of failure. However, partial safety factors of the Technical Standards and Commentaries for Port and Harbour Facilities in Japan and Coastal Engineering Manual in USA tend to estimate much bigger or smaller cross sections in comparison to the present results. Finally, many reliability re-analyses have been performed in order to conform whether the stability level of cross section estimated by Level I reliability-based design method is satisfied with the target probability of failure of partial safety factors or not.

• Journal of the Korean Recycled Construction Resources Institute
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• v.8 no.3
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• pp.276-285
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• 2020

In this study, accelerated chloride diffusion tests were performed on OPC(Ordinary Portland Cement) and FA(Fly Ash) concrete considering three levels o f W/B(Water to Binder) ratio o n 1,095 curing days. The accelerated chloride diffusion coefficient and the passed charge were evaluated in accordance with Tang's method and ASTM C 1202, and the resistance performance to chloride attack improved over time. FA concrete showed excellent resistance performance against chloride penetration with help of pozzolanic reaction. As the result of the passed charge, FA concrete showed durability improvement, "low" grade to "very low" grade, but OPC concrete changed "moderate" grade to "low" grade at 1,095 curing days. After assuming the design variables used for durability design as normal distribution functions, the service life of each case was evaluated by the probabilistic analysis method based on MCS(Monte Carlo Simulation). In FA concrete, the increase of probability of durability failure was lower than that of OPC concrete with increasing time, because the time-dependent coefficient of FA concrete was up to 3.2 times higher than OPC concrete. In addition, the service life by probabilistic analysis was evaluated lower than the service life by deterministic analysis, since the target probability of durability failure was set to 10%. It is considered that more economical durability design will be possible if the mo re suitable target probability of durability failure is set for various structures through researches on actual conditions and indoor tests under various circumstances.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.34 no.2
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• pp.37-45
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• 2022

A simplified model using the lifetime distribution has been presented to estimate the Mean Residual Life (MRL) of rubble-mound breakwaters, which is not like a stochastic process model based on time-dependent history data to the cumulative damage progress of rubble-mound breakwaters. The parameters involved in the lifetime distribution can be easily estimated by using the upper and lower limits of lifetime and their likelihood that made a judgement by several experts taking account of the initial design lifetime, the past sequences of loads, and others. The simplified model presented in this paper has been applied to the rubble-mound breakwater with TTP armor layer. Wiener Process (WP)-based stochastic model also has been applied together with Monte-Carlo Simulation (MCS) technique to the breakwater of the same condition having time-dependent cumulative damage to TTP armor layer. From the comparison of lifetime distribution obtained from each models including Mean Time To Failure (MTTF), it has found that the lifetime distributions of rubble-mound breakwater can be very satisfactorily fitted by log-normal distribution for all types of cumulative damage progresses, such as exponential, linear, and logarithmic deterioration which are feasible in the real situations. Finally, the MRL of rubble-mound breakwaters estimated by the simplified model presented in this paper have been compared with those by WP stochastic process. It can be shown that results of the presented simplified model have been identical with those of WP stochastic process until any ages in the range of MTT F regardless of the deterioration types. However, a little of differences have been seen at the ages in the neighborhood of MTTF, specially, for the linear and logarithmic deterioration of cumulative damages. For the accurate estimation of MRL of harbor structures, it may be desirable that the stochastic processes should be used to consider properly time-dependent uncertainties of damage deterioration. Nevertheless, the simplified model presented in this paper can be useful in the building of the MRL-based preventive maintenance planning for several kinds of harbor structures, because of which is not needed time-dependent history data about the damage deterioration of structures as mentioned above.

• Korean Journal of Microbiology
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• v.28 no.2
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• pp.91-97
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• 1990

Complementary DNA (cDNA) coding for human cytoplasmic superoxide dismutase (SOD1) (superoxide: superoxide oxidoreductase E.C.1.15.1.1) was isolated from human liver cDNA library of $\lambda$gt11 by in situ plaque hybridization. The insery cDNA gas the 5' untranslational region (UTR) and 3'UTR of SOD1 gene. Polymerase Chain Reaction (PCR) method was used fro subcloning of SOD1 structural gene. Using synthetic sense strand primer (24mer) containing a start codon and antisense strand primer (24mer), SOD1 structural gene was selectively amplified. Amplified DNA was directly cloned into the HincII site of pUC19 plasmid. Insery cDNA was subcloned into M13 mp19 and sequenced by dideowy chain termination method with Sequenase. The nucleotide sequence of insert cDNA had an open reading frame (ORF) coding for 153 amino acid residues. The structural gene of cytoplasmic SOD was placed under the control of bacteriophage $\lambda P_{L}$ regulatory sequences, generating a highly efficient expression plasmid. The production of human SOD1 in E. coli cells was about 7% of total cellular proteins and recombinant human SOD1 possessed its own enzymatic acitivity.

• Asian-Australasian Journal of Animal Sciences
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• v.21 no.11
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• pp.1544-1550
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• 2008

The retinoids (vitamin A and its derivatives) play a critical role in vision, growth, reproduction, cell differentiation and embryonic development. Using the IMpRH panel, porcine cellular retinol binding protein genes 5 and 7 (RBP5 and RBP7) were assigned to porcine chromosomes 5 and 6, respectively. The complete coding sequences (CDS) of the RBP5 and RBP7 genes were amplified using the reverse transcriptase polymerase chain reaction (RT-PCR) method, and the deduced amino acid sequences of both genes were compared to human corresponding proteins. The mRNA distributions of the two genes in adult Wuzhishan pig tissues (lung, skeletal muscle, spleen, heart, stomach, large intestine, lymph node, small intestine, liver, brain, kidney and fat) were examined. A total of nine single nucleotide polymorphisms (SNPs) were identified in two genes. Three of these SNPs were analyzed using the polymerase chain reaction-restriction-fragment length polymorphism (PCR-RFLP) method in Laiwu, Wuzhishan, Guizhou, Bama, Tongcheng, Yorkshire and Landrace pig breeds. Association analysis of genotypes of these SNP loci with economic traits was done in our experimental populations. Significant associations of different genotypes of $RBP5-A/G^{63}$, $RBP5-A/G^{517}$ and $RPB5-T/C^{intron1-90}$ loci with traits including maximum carcass length (LM), minimum carcass length (LN), marbling score (MS), back fat thickness at shoulder (SBF), meat color score (MCS) and hematocrit (HCT) were detected. These SNPs may be useful as genetic markers in genetic improvement for porcine production.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.22 no.2
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• pp.79-87
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• 2010

This is the first of the two papers dealing with reliability analyses for external and internal stability of a quay wall constructed on a special foundation. A new practical reliability analysis method is proposed in this paper to evaluate the quantitative risk associated with external stability of a quay wall constructed on the deep cement mixed ground. The method can consider uncertainties in various design variables. For the risk estimation to external stability of the improved soil-quay wall, three corresponding limit state functions of sliding, overturning and bearing capacity are fully defined by introducing concept of the secondary random variable. Three representative reliability methods, MVFOSM, FORM and MCS are then applied to evaluate the failure probabilities of the three limit state functions explicitly expressed in terms of the basic and secondary random variables. From the reliability analysis results, the failure probabilities obtained from the three approaches are very close to each other, and the sliding failure mode appears to be the most critical when the earthquake loading is under consideration.

• The Journal of Internal Korean Medicine
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• v.31 no.2
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• pp.356-364
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• 2010

Objectives : This study was done to evaluate the effect of stopping drinking, using alcoholic liver disease questionnaire, Diagnosis System of Oriental Medicine (DSOM) and Health Related Quality of Life (HRQOL). Methods : 49 men who satisfied the requirement participated in this trial. They stopped drinking for 6 weeks. They were analyzed using DSOM, alcoholic liver disease questionnaire and SF-36. The data were classified by age (<47,$\geq$48) and alcoholic intake per day (<100g,$\geq$100g). For HRQOL, the SF-36v2 Health Survey was used and Quality Metric Health Outcomes Scoring Software 2.0 (QualityMetric, Lincoln, RI, USA) was applied for the analysis. Results : The alcoholic liver disease questionnaire had a partial correlation with DSOM. Generally stopping drinking decreased Heat (熱). Especially in the group drinking over 100g per day, the correlation was high. In the group over 48 years old, spleen (脾) was improved comparatively. In the group with low HRQOL (PCS<31.43, MCS<23.33) deficiency (虛) was improved. Conclusions : We found that stopping drinking can improve pathogenic factors of alcoholic liver disease and the alcoholic liver disease questionnaire be a useful diagnostic method on alcoholic liver disease by comparison with DSOM.

• Applied Microscopy
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• v.36 no.4
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• pp.271-277
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• 2006

Mast cells (MCs) are granulated cells that play a pivotal role in allergic reaction and inflammation. The granules of mast cells are known to be rich in zinc (Zn). Male Sprague-Dawley rats were used. We injected $200{\mu}L$ of complete Freund's adjuvant (CFA) subcutaneously in the dorsal aspect of one hindpaw Finally, zinc selenium autometallography(AMG) was done by Danscher's method. The present study showed the ultrastructures of zinc-containing mast cells found in inflammatory area following an complete freund's adjuvant (CFA) inoculation into the rat hindpaw. At light microscopic level, mast cells were round or oval, at average $12{\mu}m$ in diameter, with many filopodia extending from the cell surface. Because the rather small and spherical nucleus was centrally placed; it was frequently obscured by the cytoplasmic granules, it sometimes could not be seen. Mast cells were distributed chiefly in the vicinity of small blood vessels. In most preparation many mast cells were ruptured and their granules escaped into the surrounding tissue. In electron micrographs, The secretory granules were at average $0.5{\mu}m$ in diameter and were limited by a membrane. The cell surface contained numerous microvilli and folds. Their interior was heterogenous in appearance. The nucleus was surrounded by large numbers of prominent vesicels and a well developed Golgi apparatus, but scant endoplasmic reticulum.