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An Improved Method for EM Radioautographic Techniques using Cork (EM Radioautographic Techniques에 관(關)한 연구(硏究) - Cork 방법(方法) -)

  • Kim, Myung-Kook;Hassler, R.
    • Applied Microscopy
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    • v.10 no.1_2
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    • pp.7-17
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    • 1980
  • Electron microscope radioautography introduced by Liquier-Milward (1956) is now used routinely in many laboratories. Most of the technical difficulties in specimen preparation have been overcome. This method is modified from loop method for improvement of EM radioautographic techniques. The advantages of this method are: 1. the use of single specimens on small corks and of a large wire loop, allows the experimenter to avoid the blemishes in the membrane; 2. the surfactant dioctyl sodium sulphosuccinate is added to diluted ILford L4, thus greatly prolonging the period of time over which good emulsion layers can be made; 3. corks can be handled in perspex holder which allows about 20 specimens to be developed simultaneously. The steps of the method comprise: 1. Cut ribbons of ultrathin sections of silver interference colour 2. Pick them up on formvar-coated 200 mesh grids 3. Prestaining of tissues 4. Coat the specimens with a thin layer of carbon by evaporation (30-60A) 5. Mount the specimens on corks (about 1cm apical diameter) using double-sided scotch tape 6. Emulsion coating; a. Take a 250m1 beaker, place it on the pan of a sliding weight balance and weigh it. Add 10 grams extra to the beam. Add pieces of ILford L4 emulsion to the beaker until the balance is swinging freely. Add the 20ml of distilled water that was previously measured out. b. Surfactant dioctyl sodium sulphosuccinate is added to diluted ILford L4. 7. Prepare a series of membranes of gelled emulsion with the wire loop and apply one to each cork-borne specimen. 8. Put the specimens away to expose by pushing the corks into short length of PVC tubing, each tube having a small hole in the side 9. Place the tubes in small boxes together with silica gel. 10. Exposure 11. Developer - Kodak Microdol X for 3 minutes 12. Fixer - A perspex holder can be manufactured which allows 20 specimens to be developed simultaneously. 12. Fixer - 30% sodium thiosulfate for 10 minutes 13. Examination with Siemens Elmiskop 1A electron microscope

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High LO-RF Isolation 94 GHz MMIC Single-balanced Mixer (높은 LO-RF 격리 특성의 94 GHz MMIC Single-balanced Mixer)

  • An, Dan;Lee, Bok-Hyung;Lim, Byeong-Ok;Kim, Sung-Chan;Lee, Sang-Jin;Lee, Mun-Kyo;Shin, Dong-Hoon;Park, Hyung-Moo;Park, Hyun-Chang;Kim, Sam-Dong;Rhee, Jin-Koo
    • Proceedings of the IEEK Conference
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    • 2005.11a
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    • pp.765-768
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    • 2005
  • In this paper, high LO-RF isolation 94 GHz MMIC single-balanced mixer was designed and fabricated using a branch line coupler and a ${\lambda}/4$ transmission line. The 94 GHz MMIC single-balanced mixer was designed using the 0.1 ${\mu}m$ InGaAs/InAlAs/GaAs Metamorphic HEMT(MHEMT) diode. The fabricated MHEMT was obtained the cut-off frequency($f_T$) of 189 GHz and the maximum oscillation frequency($f_{max}$) of 334 GHz. The designed MMIC single-balanced mixer was fabricated using 0.1 ${\mu}m$ MHEMT MMIC process. From the measurement, the conversion loss of the single-balanced mixer was 23.1 dB at an LO power of 10 dBm. The LO-RF isolations of single-balanced mixer was obtained 45.5 dB at 94.19 GHz. We obtained in this study a higher LO-RF isolation compared to some other balanced mixers in millimeter-wave frequencies.

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Evaluation of Radio-Frequency Performance of Gate-All-Around Ge/GaAs Heterojunction Tunneling Field-Effect Transistor with Hetero-Gate-Dielectric by Mixed-Mode Simulation

  • Roh, Hee Bum;Seo, Jae Hwa;Yoon, Young Jun;Bae, Jin-Hyuk;Cho, Eou-Sik;Lee, Jung-Hee;Cho, Seongjae;Kang, In Man
    • Journal of Electrical Engineering and Technology
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    • v.9 no.6
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    • pp.2070-2078
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    • 2014
  • In this work, the frequency response of gate-all-around (GAA) Ge/GaAs heterojunction tunneling field-effect transistor (TFET) with hetero-gate-dielectric (HGD) and pnpn channel doping profile has been analysed by technology computer-aided design (TCAD) device-circuit mixed-mode simulations, with comparison studies among ppn, pnpn, and HGD pnpn TFET devices. By recursive tracing of voltage transfer curves (VTCs) of a common-source (CS) amplifier based on the HGD pnpn TFET, the operation point (Q-point) was obtained at $V_{DS}=1V$, where the maximum available output swing was acquired without waveform distortion. The slope of VTC of the amplifier was 9.21 V/V (19.4 dB), which mainly resulted from the ponderable direct-current (DC) characteristics of HGD pnpn TFET. Along with the DC performances, frequency response with a small-signal voltage of 10 mV has been closely investigated in terms of voltage gain ($A_v$), unit-gain frequency ($f_{unity}$), and cut-off frequency ($f_T$). The Ge/GaAs HGD pnpn TFET demonstrated $A_v=19.4dB$, $f_{unity}=10THz$, $f_T=0.487$ THz and $f_{max}=18THz$.

Prognostic Role of C-reactive Protein in Gastric Cancer: A Meta-analysis

  • Yu, Qing;Yu, Xiong-Fei;Zhang, Shou-De;Wang, Hao-Hao;Wang, Hai-Yong;Teng, Li-Song
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.10
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    • pp.5735-5740
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    • 2013
  • Background: A number of studies have investigated the association between increased pretreatment serum C-reactive protein (CRP) levels and the prognosis of gastric cancer. However, due to the inconsistent results, whether the serum CRP level can be a prognostic factor in primary gastric cancer remains controversial. Methods: We searched Medline, PubMed, Embase and the Cochrane Central Register of Controlled Trials for relevant high-quality reports. A meta-analysis was carried out using the included studies to assess the association between pretreatment serum CRP level and overall survival (OS) in patients with gastric cancer. Correlation analyses were conducted to evaluate the relationship between serum CRP and tumor characteristics such as tumor node metastasis (TNM) stage and recurrence. Results: Twelve reports involving 2,597 patients with gastric cancer were included. Primary meta-analysis indicated a significant association between elevated CRP level and poor OS (HR 1.77, 95% CI 1.56-2.00). Subgroup analyses showed no single factor could alter the primary results when we divided the included studies by "number of patients", "max follow-up period", "TNM stage", "treatment" and "cut-off value". Correlation analyses showed that serum CRP level was significantly related to TNM stage (OR 2.96, 95% CI 2.22-3.93) and tumor recurrence (OR 1.81, 95% CI 1.21-2.71). Conclusions: We demonstrated that increased pretreatment serum CRP level (${\geq}10mg/L$) was significantly associated with poor prognosis in gastric cancer patients, either in early or advanced stages.

Clustering Strategy Based on Graph Method and Power Control for Frequency Resource Management in Femtocell and Macrocell Overlaid System

  • Li, Hongjia;Xu, Xiaodong;Hu, Dan;Tao, Xiaofeng;Zhang, Ping;Ci, Song;Tang, Hui
    • Journal of Communications and Networks
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    • v.13 no.6
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    • pp.664-677
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    • 2011
  • In order to control interference and improve spectrum efficiency in the femtocell and macrocell overlaid system (FMOS), we propose a joint frequency bandwidth dynamic division, clustering and power control algorithm (JFCPA) for orthogonal-frequency-division-multiple access-based downlink FMOS. The overall system bandwidth is divided into three bands, and the macro-cellular coverage is divided into two areas according to the intensity of the interference from the macro base station to the femtocells, which are dynamically determined by using the JFCPA. A cluster is taken as the unit for frequency reuse among femtocells. We map the problem of clustering to the MAX k-CUT problem with the aim of eliminating the inter-femtocell collision interference, which is solved by a graph-based heuristic algorithm. Frequency bandwidth sharing or splitting between the femtocell tier and the macrocell tier is determined by a step-migration-algorithm-based power control. Simulations conducted to demonstrate the effectiveness of our proposed algorithm showed the frequency-reuse probability of the FMOS reuse band above 97.6% and at least 70% of the frequency bandwidth available for the macrocell tier, which means that the co-tier and the cross-tier interference were effectively controlled. Thus, high spectrum efficiency was achieved. The simulation results also clarified that the planning of frequency resource allocation in FMOS should take into account both the spatial density of femtocells and the interference suffered by them. Statistical results from our simulations also provide guidelines for actual FMOS planning.

A Study on Typical Rates of Water-use for Primary School, Middle School and High School Facilities (초.중.고등학교 시설의 급수 사용량에 대한 연구)

  • Kim, Kyu-Saeng
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.20 no.12
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    • pp.802-807
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    • 2008
  • A Study on Typical Rates of Water-use for School Facilities has been carried out in this work. Water supply system is given much weight in school facilities. Therefore, it set up a basis efficiency using of water sources to calculate typical rates of water use. The results are summarized as follows; 1) On the whole, typical rates of water-use was founded out 15 L/stu. d in pirmary school, 10 L/stu. d in middle school and 30 L/stu. d in high school smaller than the existing it. It was rate of water-use change as season and Max. Rates of water-use was July. 2) I deem that school hours are 5 hour's in primary school, 7 hour's in middle school and 8 hour's in high school. It the concept of 1 hour that is lesson time 40 minutes and resting time 10 minutes in primary school, lesson time 45 minutes and resting time 10 minutes in middle school and lesson time 50 minutes and resting time 10 minutes in high school. 3) It is desired that we calculate the volume of pump and water tank throughout this concept and the size of water tank should be 1.5 times with taking peak load into consideration by this study on typical rate of water-use. 4) The amount of using water increases in gradually and I consider the life cycle of facilities is more than 10 years. As a result, I can forecast that the size will be insufficiency but I deem that if we devise a plan about parallel pumping on water tank space, we can cope with it. Also, it is expected that we can cut back the transport energy by controlling pump volume.

A Study on Typical Rates of Water-use for Primary School, Middle School and High School Facilities (초.중.고등학교 시설의 급수 사용량에 대한 연구)

  • Kim, Kyu-Saeng
    • Proceedings of the SAREK Conference
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    • 2007.11a
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    • pp.510-515
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    • 2007
  • A Study on Typical Rates of Water-use for School Facilities has been carried out in this work. Water supply system is given much weight in school facilities. Therefore, it set up a basis efficiency using of water sources to calculate typical rates of water use. The results are summarized as follows ; 1) On the whole, typical rates of water-use was founded out 15 L / stu. d in pirmary school, 10 L / stu. d in middle school and 30L / stu. d in high school smaller than the existing it. It was rate of water-use change as season and Max. Rates of water-use was July. 2) I deem that school hours are 5 hour's in primary school, 7 hour's in middle school and 8 hour's in high school. It the concept of 1 hour that is lesson time 40 minutes and resting time 10 minutes in primary school, lesson time 45 minutes and resting time 10 minutes in middle school and lesson time 50 minutes and resting time 10 minutes in high school. 3) It is desired that we calculate the volume of pump and water tank throughout this concept and the size of water tank should be 1.5 times with taking pick load into consideration by this study on typical rate of water-use. 4) The amount of using water increases in gradually and I consider the life cycle of facilities is more than 10 years. As a result, I can forecast that the size will be insufficiency but I deem that if we devise a plan about parallel pumping on water tank space, we can cope with it. Also, it is expected that we can cut back the transport energy by controlling pump volume.

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Effects of Circulating Coolant in High Temperature Season and warm Water in Low Temperature Season by Controlling Soil Temperature on the Growth and Flower Quality in Alstroemeria (하절기 및 동절기 근권부 온도조절이 알스트로메리아 절화 생육 및 품질에 미치는 영향)

  • Cho, Kyung Chul;Hwang, In Taek;Kim, Hee Gon;Ki, Gwang Yeon;Kim, Byeong Sam;Yoon, Bong Ki;Kim, Jeong Keun;Choi, Kyung Ju;Han, Tae Ho
    • FLOWER RESEARCH JOURNAL
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    • v.19 no.4
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    • pp.187-191
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    • 2011
  • Rising soil temperature was effectively controled by shading net of 50% and cooled water to maintain average $18.8^{\circ}C$ (maximum $23^{\circ}C$), then shading net of 50% and ground water to maintain average $23.2^{\circ}C$ (max. $28.5^{\circ}C$), shading paint of 30% and shading net (50%) to maintain average $24^{\circ}C$ (max. $30^{\circ}C$) in that order. Alstroemeria 'Modena' most affected by shading and cooling water was better in shoot length as 95.9 cm and fresh weight as 67 g than those of other treatments. The production of cut flower was increased more 121% with treatment 50% shading net and cooling water, 59% with 50% shading net and ground water, and 65% with 30% shading paint than that of 50% shading net, respectively. Soil temperature was higher $8^{\circ}C$ with the plot of circulating warm water than untreated control plot. Alstroemeria 'Aspen', 'Modena', and 'Chanel' increased more plant growth such as plant height, fresh weight in warm water than in untreated control plot, but Alstroemeria 'Bordeaux' decreased plant height. Because of increasing plant growth, flower quality such as peduncle length, peduncle diameter, floret number and flower weight of 4 all cultivar was better in the plot of circulating warm water than untreated control plot. Also, the production of cut flower was increased the most in Alstroemeria 'Modena' by 38%, 'Aspen', 'Bordeaux', and 'Chanel' in that order.

The Differentiation of Benign from Maligant Soft Tissue Lesions using FDG-PET: Comparison between Semi-quantitative Indices (FDG-PET을 이용한 악성과 양성 연부조직 병변의 감별: 반정량적 지표간의 비교)

  • Choi, Joon-Young;Lee, Kyung-Han;Choe, Yearn-Seong;Choi, Yong;Kim, Sang-Eun;Seo, Jai-Gon;Kim, Byung-Tae
    • The Korean Journal of Nuclear Medicine
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    • v.31 no.1
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    • pp.90-101
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    • 1997
  • The purpose of this study is to evaluate the diagnostic accuracy of various quantitative indices for the differentiation of benign from malignant primary soft tissue tumors by FDG-PET. A series of 32 patients with a variety of histologically or clinically confirmed benign (20) or malignant (12) soft tissue lesions were evaluated with emission whole body (5min/bed position) PET after injection of [$^{18}F$]FDG. Regional 20min transmission scan for the attenuation correction and calculation of SUV was performed in 16 patients (10 benign, 6malignant) followed by dynamic acquisition for 56min. Postinjection transmission scan for the attenuation correction and calculation of SUV was executed in the other 16 patients (10 benign, 6 malignant). The following indices were obtained. the peak and average SUV (pSUV, aSUV) of lesions, tumor-to-background ratio acquired at images of 51 min p.i. ($TBR_{51}$), tumor-to-background ratio of areas under time-activity curves ($TBR_{area}$) and the ratio between the activities of tumor ROI at 51 min p. i. and at the time which background ROI reaches maximum activity on the time-activity curves ($T_{51}/T_{max}$). The pSUV, aSUV, $TBR_{51}$, and $TBR_{area}$ in malignant lesions were significantly higher than those in benign lesions. We set the cut-off values of pSUV, aSUV, $TBR_{51},\;TBR_{area}$ and $T_{51}/T_{max}$ for the differentiation of benign and malignant lesions at 3.5, 2.8, 5.1, 4.3 and 1.55, respectively. The sensitivity, specificity and accuracy were 91.7%, 80.0%, 84.4% by pSUV and aSUV, 83.3%, 85.0%, 84.4% by $TBR_{51}$, 83.3%, 100%, 93.8% by $TBR_{area}$ and 66.7%, 70.0%, 68.8% by $T_{51}/T_{max}$. The time-activity curves did not give additional information compared to SUV or TBR. The one false negative was a case with low-grade fibrosarcoma and all four false positives were cases with inflammatory change on histology. The visual, analysis of FDG-PET also detected the metastatic lesions in malignant cases with comparable accuracy In conclusion, all pSUV, aSUV, $TBR_{51}$, and $TBR_{area}$ are useful metabolic semi-quantitative indices with good accuracy for the differentiation of benign from malignant soft-tissue lesions.

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Rotary Veneer Peeling of Some Softwoods and Its Veneer Drying (수종(數種)의 침엽수재(針葉樹材)의 로타리 단판(單板) 절삭(切削)과 건조(乾燥))

  • Jung, Hee-Suk;Lee, Nam-Ho;Yeo, Hwan-Myeong;Lee, June-Ho;Yoo, Tae-Kyung
    • Journal of the Korean Wood Science and Technology
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    • v.24 no.1
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    • pp.34-47
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    • 1996
  • Veneers of two nominal thicknesses, 1.5 and 2.5mm, were rotary peeled from Japanese larch (Larix leptolepis). Dahurian larch (Larix gmelinei) and Radiata pine (Pinus radiata) bolts unheated and heated in the water vat temperature of $66^{\circ}C$ by rising a final temperature at 10cm core of $60^{\circ}C$ to remain core diameter of 11.4cm. 1.5 and 2.5mm thick veneer cut from the heated Japanese larch were significantly thinner than those of the unheated bolt and 2.5mm thick veneer cut from the heated Dahurian larch were significantly thicker than that of the unheated bolt. 1.5mm thick Dahurian larch veneer and 1.5 and 2.5mm thick Radiata pine veneers showed insignificant difference between the unheated and heated bolts, respectively. Check distance on the loose side of 1.5mm thick veneer cut from the heated Radiata pine was significantly wider than that of the unheated bolt. However check distances on the loose side of 1.5 and 2.5mm thick Japanese larch and Dahurian larch veneers and 2.5mm thick Radiata pine veneers showed insignificant difference between the unheated and heated bolts. Also the depth of check on the loose side of three species showed insignificantly difference between the unheated and heated bolts. Arithmatic mean deviation($R_a$) and maximum height($R_{max}$) of the profile on the loose side of dried veneer by preheating the bolt compared with unheated bolts were different among apecies and between veneer thickness. The preheating treatment slightly affected qualities of these thin veneers such as 1.5 and 2.5mm. The yield of 2.5mm thick veneer from the heated radiata pine was significantly higher than that of the unheated bolt. However the yield of 2.5mm thick veneer for other two species and 1.5mm thick veneer for three species showed insignificant difference between the unheated and heated bolts. The yield of 2.5mm thick veneer for three species were higher than those of 1.5mm thick veneer. The average yields of green veneer of Japanese larch. Dahurian larch and Radiata pine were 57.1, 55.1 and 54.0 percent, respectively. Variables such as initial MC. drying time and veneer thickness had strong effect for Japanese larch veneer, less effect for Radiata pine veneer and nuch less effect on final MC for Dahurian larch veneer in jet drying. Correlation between the current MC and the drying time of Dahurian larch with low variation of initial MC was higher than those of Japanese larch and Radiata pine veneer with high variation of initial MC in high temperature drying. Thickness shrinkages of 2.5mm thick veneer for Japanese larch and Radiata pine were higher than those of 1.5mm thick veneers, but shrinkages of Dahurian larch veneer were similar between two nominal veneer thicknesses.

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