• Communications of the Korean Mathematical Society
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• v.19 no.1
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• pp.159-167
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• 2004

In [1], a relative root Nielsen number $N_{rel}(f;\;c)$ is introduced which is a homotopy invariant lower bound for the number of roots at $c\;{\in}\;Y$ for a map of pairs of spaces $f\;:\;(X,\;A)\;{\rightarrow}\;(Y,\;B)$. In this paper, we obtain a minimum theorem for $N_{rel}(f;\;c)$ under some new assumptions on the spaces and maps which are different from those in [1].

• Journal of the Korean Applied Science and Technology
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• v.30 no.1
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• pp.173-182
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• 2013

Atopic dermatitis is a chronic, relapsing inflammatory skin disease associated with dysfunction of skin barrier and cutaneous hyper-reactivity to environmental triggers. In the previous study, cytotoxicity, antioxidant, anti-inflammatory and anti-allergic activities were investigated for various herbal extracts such as Aloe vera L. (AV), Viola mandshurica W. Becker (VM), Punica granatum L. (PG), and Dendrobium nobile L. (DN) in order to develop effective therapeutic herbal extracts for atopic dermatitis, In this study, anti-inflammatory activities of these herb extracts in lipopolysaccharide (LPS)-induced macrophage RAW264.7 cells were further examined to find the underlying molecular mechanisms. The RT-PCR (reverse transcription polymerase chain reaction) analysis showed that PG, DN and AV inhibited effectively the gene expression of pro-inflammatory cytokines IL-6 and IL-$1{\beta}$ in LPS-stimulated macrophages, while VM did not. The transfection and luciferase analysis exhibited that all herbal extracts hindered the activation of transcription nuclear factor kappa B (NF-${\kappa}B$). The western blot analysis indicated that AV blocked the activation of only JNK MAP (c-Jun N-terminal kinase mitogen-activated protein) kinase not p38 MAP kinase, while VM, PG and DN did not show the activation of both JNK and p38 MAP kinases. These results suggest that AV, VM, PG, and DN have anti-inflammatory activities and thus have the potential to reduce and alleviate the symptoms of atopic dermatitis.

• Journal of the Korean Institute of Telematics and Electronics B
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• v.29B no.11
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• pp.111-119
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• 1992

In this paper, we propose an edge detection scheme for noisy images based on the co-occurrence matrix. In the proposed scheme based on the step edge model, the gray level information is simply converted into a bit-map, i.e., the uniform and boundary regions of an image are transformed into a binary pattern by using the local mean. In this binary bit-map pattern, 0 and 1 densely distributed near the boundary region while they are randomly distributed in the uniform region. To detect the boundary region, the co-occurrence matrix on the bit-map is introduced. The effectiveness of the proposed scheme is shown via a quantitative performance comparison to the conventional edge detection methods and the simulation results for noisy images are also presented.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.29 no.2
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• pp.162-167
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• 1993

We have investigated analytically and numerically on both the generalized dimension D sub(n) and the fractal dimensionality f sub($\alpha$) in the dissipative Willbrink map. and discussed both the mode-locking phenomenon and the dissipative trajectory when z=0.03, b=0.9 and K sub(d) =0.272313668. In the mode-locking phenomenon. we find that the generalized dimension D sub(-n) and superconverged $\delta$ sub(n) are very close to D sub(-$\infty$) =0.92403 and $\delta$ sub($\infty$) =2.16442 even for n～20 as listed in Table 1. In dissipative trajectory, the values of D sub(+n) and D sub(-n) for n～20 are estimated to be very close to D sub(+$\infty$) =0.63267 and D sub(-$\infty$) =1.89802 on the circle map. Thus, the values of the generalized dimension as nlongrightarrow$\infty$ on dissipative Willbrink map are expected to be the same results as those for the circle map and to have the universal scaling exponents for a special scaling structure when the values of overbar(w), z, b, and k sub(d) have the different values.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.1
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• pp.141-150
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• 2010

In this paper, performance of a turbo-coded OFDM system is analyzed and simulated in a power line communication channel. Since the power line communication system typically operates in a hostile environment, turbo code has been employed to enhance reliability of transmitted data. The performance is evaluated in terms of bit error probability. As turbo decoding algorithms, MAP (maximum a posteriori), Max-Log-MAP, and SOVA (soft decision viterbi output) algorithms are chosen and their performances are compared. From simulation results, it is demonstrated that Max-Log-MAP algorithm is promising in terms of performance and complexity. It is shown that performance is improved 3dB by increasing the number of iterations, 2 to 8, and interleaver length of a turbo encoder, 100 to 5000. The results in this paper can be applied to OFDM-based high-speed power line communication systems.

• Proceedings of the Zoological Society Korea Conference
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• 2001.10a
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• pp.200.2-200
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• 2001

No Abstract, See Full Text

• The Korean Journal of Physiology and Pharmacology
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• v.14 no.5
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• pp.265-272
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• 2010

Follicular cystic ovary (FCO) is one of the most frequently diagnosed ovarian diseases and is a major cause of reproductive failure in mammalian species. However, the mechanism by which FCO is induced remains unclear. Genetic alterations which affect the functioning of many kinds of cells and/or tissues could be present in cystic ovaries. In this study, we performed a comparison analysis of gene expression in order to identify new molecules useful in discrimination of bovine FCO with follicular cystic follicles (FCFs). Normal follicles and FCFs were classified based on their sizes (5 to 10 mm and $\geq25mm$). These follicles had granulosa cell layer and theca interna and the hormone $17{\beta}$-estradiol ($E_2$)/ progesterone ($P_4$) ratio in follicles was greater than one. Perifollicular regions including follicles were used for the preparation of RNA or protein. Differentially expressed genes (DEG) that showed greater than a 2-fold change in expression were screened by the annealing control primer (ACP)-based PCR method using $GeneFishing^{TM}$ DEG kits in bovine normal follicles and FCFs. We identified two DEGs in the FCFs: ribosomal protein L15 (RPL15) and microtubule-associated protein 1B (MAP1B) based on BLAST searches of the NCBI GenBank. Consistent with the ACP analysis, semi-quantitative PCR data and Western blot analyses revealed an up-regulation of RPL15 and a down-regulation of MAP1B in FCFs. These results suggest that RPL15 and MAP1B may be involved in the regulation of pathological processes in bovine FCOs and may help to establish a bovine gene data-base for the discrimination of FCOs from normal ovaries.

• Journal of the Korean Mathematical Society
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• v.46 no.6
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• pp.1219-1232
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• 2009

Let H(B) denote the space of all holomorphic functions on the unit ball B of $\mathbb{C}^n$. Let $\varphi$ = (${\varphi}_1,{\ldots}{\varphi}_n$) be a holomorphic self-map of B and $g{\in}2$(B) with g(0) = 0. In this paper we study the boundedness and compactness of the generalized composition operator $C_{\varphi}^gf(z)=\int_{0}^{1}{\mathfrak{R}}f(\varphi(tz))g(tz){\frac{dt}{t}}$ from generalized weighted Bergman spaces into Bloch type spaces.

• Food Science of Animal Resources
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• v.33 no.1
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• pp.58-66
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• 2013

In this study, the effect of packaging methods [aerobic packaging (AP), vacuum packaging (VP) and modified atmosphere packaging (MAP: 75% $N_2$, 25% $CO_2$)] on colour, lipid quality and microbial growth of beef patties enhanced with flaxseed flour was investigated during storage at $2{\pm}1^{\circ}C$ for 10 d. L and a values of beef patties packaged in MAP and VP were higher (p<0.05) than that of the samples packaged in AP. Packaging in MAP and VP retarded the lipid oxidation (TBA value) and inhibited the bacterial growth of beef patties enhanced with flaxseed flour. Furthermore, TBA values in beef patties were correlated with a values (r = -0.340; p<0.05). Packaging in MAP was more effective than packaging in VP for inhibiting microbial growth. The samples packaged in VP lost their shape due to the compression by external atmosphere. Packaging treatment had no significant effect on saturated fatty acid (SFA), monounsaturated fatty acid (MUFA) and polyunsaturated fatty acid (PUFA) levels in beef patties. The a and b, TBA and MUFA values changed during storage time. TBA values for beef patties increased during storage time, but did not reach to the limit value (1 mg/kg) until the end of the storage time. The results suggest that the shelf life of beef patties enhanced with flaxseed flour can be extended by packaging in MAP.

• Archives of Pharmacal Research
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• v.26 no.9
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• pp.739-746
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• 2003

Ultraviolet B (UVB) is known to induce apoptosis in human melanocytes. Here we show the cytoprotective effect of sphingosine-1-phosphate (S1P) against UVB-induced apoptosis. We also show that UVB-induced apoptosis of melanocytes is mediated by caspase-3 activation and poly(ADP-ribose) polymerase (PARP) cleavage, and that S1P prevents apoptosis by inhibiting this apoptotic pathway. We further investigated three major mitogen-activated protein (MAP) kinases after UVB irradiation. UVB gradually activated c-Jun N-terminal kinase (JNK) and p38 MAP kinase, while extracellular signal-regulated protein kinase (ERK) was inactivated transiently. Blocking of the p38 MAP kinase pathway using SB203580 promoted cell survival and inhibited the activation of caspase-3 and PARP cleavage. These results suggest that p38 MAP kinase activation may play an important role in the UVB-induced apoptosis of human melanocytes. To explain this cytoprotective effect, we next examined whether S1P could inhibit UVB-induced JNK and p38 MAP kinase activation. However, S1P was not found to have any influence on UVB-induced JNK or p38 MAP kinase activation. In contrast, S1P clearly stimulated the phosphorylation of ERK, and the specific inhibition of the ERK pathway using PD98059 abolished the cytoprotective effect of S1P. Based on these results, we conclude that the activation of p38 MAP kinase plays an important role in UVB-induced apoptosis, and that S1P may show its cytoprotective effect through ERK activation in human melanocytes.