• Journal of Life Science
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• v.13 no.4
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• pp.375-382
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• 2003

A direct and precise explanation of soybean resistance to soybean cyst nematode will be possible only when the individual gene(s) involved in the resistance are tagged. This study was conducted, (1) to identify and localize quantitative trait loci for resistance to soybean cyst nematode race 14 on RAPD map, (2) to identify the magnitude and mode of inheritance for each quantitative trait loci, and (3) to identify the best combinations of quantitative trait loci for resistance to soybean cyst nematode race 14. Thirty markers (29 RAPD and 1 RFLP) showed significant association with resistance to soybean cyst nematode race 14. From MAPMAKER/QTL analysis, we identified two regions (linkage group C-7 and linkage group C-9) for resistance to soybean cyst nematode .ace 14. The first quantitative trait loci that was localized at 6.0 cM from $H06^1$ on linkage group C-7 showed a dominant inheritance mode. However, we can not exclude the possibility of additive inheritance mode. The second quantitative trait loci that was localized between $B15^2$ and $E01^1$ on linkage group C-9 also showed a dominant mode of inheritance. One pair of flanking markers ($H06^1$ and $H06^2$) and B15$^2$ were used for multiple regression analysis. Marker combination that included 2 markers, $B15^2$ and $H06^1$, explained the highest total variance (22.9%) for resistance to soybean cyst nematode race 14. Further localization of genes for resistance to soybean cyst nematode race 14 and examination of interaction between quantitative trait loci will accelerate the exploitation of resistance to soybean cyst nematode.

• The Journal of Korean Obstetrics and Gynecology
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• v.28 no.2
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• pp.1-14
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• 2015

Objectives : This study was designed to investigate the effects of Taraxaci Herba (TH) on cell death in breast cancer cells. Methods : In this experiment, the effects of TH on proliferation rates, cell morphology and growth pattern, intracellular reactive oxygen species (ROS) production. In addition, the effects on nuclear condensation, fragmentation and formation of acidic vesicular organelles (AVO) in MCF-7 cells were also investigated. Finally, autophagy related with protein was observed by using western blot method. Results : TH inhibited proliferation of MCF-7 cells, TH elevated intracellular ROS levels significantly. Treatment with TH did not affect nuclear morphologies such as condensation or fragmentation. On the other hand, TH treatment effectively induced AVO. Finally, one of autophagy related with protein, Microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A, LC3) level was elevated by treatment with TH. Conclusions : These data indicate that TH is able to be used for patient with breast cancer and mechanisms are involved in autophagy through ROS generation.

• Journal of the Korean Society for Heat Treatment
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• v.28 no.4
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• pp.171-180
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• 2015

The variation in microstructure and texture during continuous annealing was examined in a series of 1.6% Mn-0.1% Cr-0.3% Mo-0.005% B steels with carbon contents in the range of 0.010 to 0.030%. It was found that microstructure of hot band consisted of ferrite and pearlite as a consequence of high coiling temperature, and eutectoid carbon content was between 0.011% and 0.016%. Martensite ranged in volume fraction from 1.5% to 4.0% when annealed at $820{\circ}C$ according to the typical continuous annealing cycle. The critical martensite content for the continuous yielding was about 4% from stress-strain curves. The continuous yielding was obtained in the 0.030% carbon steel and 0.010% to 0.020% carbon steels revealed some yield point elongation ranging from 0.8% to 2.2% in as-annealed conditions. Higher tensile strength in the higher carbon steel is due to both increase in the martensite volume fraction and ferrite grain refinement. Decreasing the carbon content to 0.01% strengthened the intensities of ${\gamma}$-fiber textures, resulting in the increase in the $r_m$ value, which was caused by the lower volume fraction of martensite. The higher carbon steels showed the lower $r_m$ value of about 1.0.

• Journal of Plant Biology
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• v.12 no.4
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• pp.19-29
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• 1969

This study investigated the vertical distribution of the vegetation in Mt. Hanla of Quelpart Island from 1967 to 1969. According to the physiognomy and life form of plants, the following plant communities are observed and arranged tentatively from the foot to the top. A. North-facing slope. (1) Grass land(0∼600m) (2) Deciduous broad-leaved forest(600∼1200m) (3) Mixed forest(broad and needle leaved forest : 1200∼1300m) (4) Evergreen coniferous forest(1300∼1700m) (5) Scrub communities(1700∼1950m) B. South-facing slope. (1) Grass land(0∼700) (2) Deciduous broad-leaved forest(700∼1300m) (3) Mixed forest(1300∼1550m) (4) Evergreen coniferous forest (1550∼850m) (5) Scrub communities(1850∼1950m) D. West-facing slope. (1) Grass land(0∼650) (2) Deciduous brod-leaved forest(650∼1400m) (3) Mixed forest(1400∼1500m) (4) Evergreen coniferous forest(1500∼1750m) (5) Scrub communities(1750∼1950m) The relation of the geological map and vegetation are as follows: (1) In the region of lava of Mt. Hanla are mainly distribut4ed deciduous broad-leaved forest. (2) In the region of Mt. Hanla are mainly distributed scrub. (3) In the region of lava of Gogun-san are involved deciduous broad-leaved forest, scrub and grass land of Gaimi-Dung.

• Geomechanics and Engineering
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• v.4 no.1
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• pp.1-18
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• 2012

The spatial variation of ground motion in Kolkata Metropolitan District (KMD) has been estimated by generating synthetic ground motion considering the point source model coupled with site response analysis. The most vulnerable source was identified from regional seismotectonic map for an area of about 350 km radius around Kolkata. The rock level acceleration time histories at 121 borehole locations in Kolkata for the vulnerable source, Eocene Hinge Zone, due to maximum credible earthquake (MCE) moment magnitude 6.2 were generated by synthetic ground motion model. Soil investigation data of 121 boreholes were collected from the report of Soil Data Bank Project, Jadavpur University, Kolkata. Surface level ground motion parameters were determined using SHAKE2000 software. The results are presented in the form of peak ground acceleration (PGA) at rock level and ground surface, amplification factor, and the response spectra at the ground surface for frequency 1.5 Hz, 3 Hz, 5 Hz and 10 Hz and 5% damping ratio. Site response study shows higher PGA in comparison with rock level acceleration. Maximum amplification in some portion in KMD area is found to be as high as 3.0 times compared to rock level.

• Wind and Structures
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• v.37 no.2
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• pp.79-94
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• 2023

This paper traces the drafting of the new EN 1991-1-4 Eurocode 1 - Actions on structures - Part 1-4: General actions - Wind actions within Mandate M/515 of the European Commission to CEN, for the evolution of structural Eurocodes towards their Second Generation. Work of the Project Team started in August 2017 and ended in April 2020, with delivery of a final draft for public enquiry. The revised document contains several modifications with respect to the existing 2005 version, and new sections were added, covering aspect not dealt with in the previous version. It has a renovated structure, with a main text limited in size and containing only fundamental material; all the remaining information, either normative or informative is arranged into thirteen annexes. Common to other Eurocode Parts, general requests from CEN were those of reducing the number of Nationally Determined Parameters and of enhancing the ease of use. More specific requests were those of (a) the drafting of a European design wind map, (b) improving wind models, (c) reviewing force and pressure coefficients, (d) reviewing the procedures for evaluation of the dynamic response, as well as (e) making editorial improvements aimed at a more user friendly document. The author had the privilege to serve as Project Team member for the drafting of the new document, and this paper brings his personal view concerning some general aspects of wind code writing, and some more specific aspects about the particular document.

• The Korea Journal of Herbology
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• v.31 no.2
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• pp.63-69
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• 2016

Objectives : The aerial parts of Agrimonia pilosa Ledeb (Agrimoniae Herba; AH) has been traditionally used as a Korean medicine to treatment of abdominal pain, sore throat, headaches, bloody discharge, parasitic infections and eczema. In this study, we investigated the effect of AH ethanol extract on lipopolysaccharide (LPS)-induced inflammation in RAW264.7 macrophage cells.Methods : AH was extracted by 30% ethanol (AH-E). Raw264.7 cells were treated with AH-E extract at different concentrations for 30 min and then stimulated with LPS (1㎍/㎖) or without for indicated times. Cell viability was measured by MTT assay, and nitric oxide (NO) production was measured by Griess assay. The expression of inflammatory mediators, iNOS and COX-2 and inflammatory cytokines, TNF-α, IL-1β, and IL-6 was detected by RT-PCR, and the phosphorylation of ERK1/2, p38 and JNK MAP kinases (MAPKs) was analyzed by Western blot. Also, the expression of NF-κB in nuclear and cytosol was detected by Western blot.Results : AH-E extract significantly decreased LPS-induced NO production in RAW264.7 cells. AH-E extract inhibited the mRNA expression of iNOS, COX-2, TNF-α, IL-1β, and IL-6 in LPS-stimulated cells with a dose-dependent manner. In addition, the phosphorylation of ERK, p38 and JNK MAPKs was also inhibited by AH-E extract. AP-E extract inhibited the nuclear translocation of NF-κB in LPS-stimulated cells.Conclusions : Our results suggest that AH-E extract has an anti-inflammatory activity in macrophages-mediated inflammation.

• Journal of Korean Academy of Nursing Administration
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• v.1 no.1
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• pp.22-34
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• 1995

Health care marketing can be defined as a process of developing, promoting and administering health care services for the benefits of hospitals as well as consumers. Researchers have reported that one of the significant attributes in the selection of hospital is a client's perceived image of the hospitals. Especially the image of nursing services was one of the important factors of the hospital image. The main purposes of the study were 1) to define the positioning about 5 hospitals' image of nursing services. 2) to define the effects of image attributes to the iamage of hospital nursing services. Eighteen hundred questionnaires were distributed to the parents of middle schools and high schools in Seoul. Among them, 1340 cases were returned but 849 cases were turned out to be useful data and used in final analysis. In data analysis, $SPSS\;/PC^+$ and PC-MDS programs were used for descriptive statistics, multiple regression, and drawing perceptual maps. The image of hospital nursing services was measured developed by the author through literature review and content validation. Reliability coefficients was found to be statistically appropriate level of confidence(Cronbach's Alpha=.8617). The results were as follows : 3) The perceptual map shows that hospital A, B and C,D,E were divided into five groups(See Fig. 1). That is, hospital A, and B are located in a close position and hopital C & E are located at opposite position between X-axis, Hospital D was located in the middle area of the hospital C and:E. In conclusion, this research visiblely depicted perceptual maps using MDS of the consumer's image about hospital nursing services. Since hopital nursing services were differentiated by the image attributes in consumer's perception, the results of the study can help hospital managers plan marketing strategy according to their strong points or weak points. Because the necessity of marketing in recent health care was importantly recognized, this research which is adopting posititioning concept will contribute to the consumers and hospital organizations.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.30 no.6B
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• pp.533-540
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• 2010

Recently management of vegetation distributed in the watercourse is very important not only for safety but also for river restoration. In general, vegetations in the watercourse increase hydraulic resistance and accordingly decrease conveyance capacity which may yield levee overflow. This paper simulates water level rise using 1D and 2D hydro dynamic model to check the possibility of overflow in downstream of the Soyang Reservoir by assigning different roughness coefficient corresponding to different types of vegetation. In this study, 3 different vegetation types of tree, shrub, and main channel were considered and corresponding Manning's roughness coefficient n was assigned based on the vegetation map generated from the site investigation. As results, the water level raised about 0.1 to 0.7 m comparing with the case without considering vegetation and a proper measurements is necessary where overflow occurs due to low level levee.

• Journal of the Korean Association of Geographic Information Studies
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• v.16 no.3
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• pp.193-210
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• 2013

This study aims to assess the slope stability variation of Jeollabuk-do drainage areas by RCM model outputs based on A1B climate change scenario and infinite slope stability model based on the specific catchment area concept. For this objective, we downscaled RCM data in time and space: from watershed scale to rain gauge scale in space and from monthly data to daily data in time and also developed the GIS-based infinite slope stability model based on the concept of specific catchment area to calculate spatially-distributed wetness index. For model parameterization, topographic, geologic, forestry digital map were used and model parameters were set up in format of grid cells($90m{\times}90m$). Finally, we applied the future daily rainfall data to the infinite slope stability model and then assess slope stability variation under the climate change scenario. This research consists of two papers: the first paper focuses on the methodologies of climate change scenario preparation and infinite slope stability model development.