• Bulletin of the Korean Mathematical Society
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• v.61 no.1
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• pp.117-133
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• 2024

Let 𝓟 = {X_i : i ∈ I} be a partition of a set X. We say that a transformation f : X → X preserves 𝓟 if for every X_i ∈ 𝓟, there exists X_j ∈ 𝓟 such that X_if ⊆ X_j. Consider the semigroup 𝓑(X, 𝓟) of all transformations f of X such that f preserves 𝓟 and the character (map) χ^(f): I → I defined by i_χ^(f) = j whenever X_if ⊆ X_j is bijective. We describe Green's relations on 𝓑(X, 𝓟), and prove that 𝒟 = 𝒥 on 𝓑(X, 𝓟) if 𝓟 is finite. We give a necessary and sufficient condition for 𝒟 = 𝒥 on 𝓑(X, 𝓟). We characterize unit-regular elements in 𝓑(X, 𝓟), and determine when 𝓑(X, 𝓟) is a unit-regular semigroup. We alternatively prove that 𝓑(X, 𝓟) is a regular semigroup. We end the paper with a conjecture.

• Bulletin of the Korean Mathematical Society
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• v.61 no.1
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• pp.195-205
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• 2024

In this paper, we consider the set of periodic shadowable points for homeomorphisms of a compact metric space, and we prove that this set satisfies some properties such as invariance and being a G_δ set. Then we investigate implication relations related to sets consisting of shadowable points, periodic shadowable points and uniformly expansive points, respectively. Assume that the set of periodic points and the set of periodic shadowable points of a homeomorphism on a compact metric space are dense in X. Then we show that a homeomorphism has the periodic shadowing property if and only if so is the restricted map to the set of periodic shadowable points. We also give some examples related to our results.

• Korean Journal of Remote Sensing
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• v.38 no.2
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• pp.167-177
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• 2022

In order to obtain satellite image products using the image transmitted to the ground station after capturing the satellite images, many image pre/post-processing steps are involved. During the pre/post-processing, when converting from level 1R images to level 1G images, geometric correction is essential. An interpolation method necessary for geometric correction is inevitably used, and the quality of the level 1G images is determined according to the accuracy of the interpolation method. Also, it is crucial to speed up the interpolation algorithm by the level processor. In this paper, we proposed a lightweight CNN-based interpolation method required for geometric correction when converting from level 1R to level 1G. The proposed method doubles the resolution of satellite images and constructs a deep learning network with a lightweight deep convolutional neural network for fast processing speed. In addition, a feature map fusion method capable of improving the image quality of multispectral (MS) bands using panchromatic (PAN) band information was proposed. The images obtained through the proposed interpolation method improved by about 0.4 dB for the PAN image and about 4.9 dB for the MS image in the quantitative peak signal-to-noise ratio (PSNR) index compared to the existing deep learning-based interpolation methods. In addition, it was confirmed that the time required to acquire an image that is twice the resolution of the 36,500×36,500 input image based on the PAN image size is improved by about 1.6 times compared to the existing deep learning-based interpolation method.

• Molecules and Cells
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• v.40 no.5
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• pp.371-377
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• 2017

Despite the importance of the receptor activator of nuclear factor (NF)-kappaB ligand (RANKL)-RANK signaling mechanisms on osteoclast differentiation, little has been studied on how RANK expression is regulated or what regulates its expression during osteoclastogenesis. We show here that insulin signaling increases RANK expression, thus enhancing osteoclast differentiation by RANKL. Insulin stimulation induced RANK gene expression in time- and dose-dependent manners and insulin receptor shRNA completely abolished RANK expression induced by insulin in bone marrow-derived monocyte/macrophage cells (BMMs). Moreover, the addition of insulin in the presence of RANKL promoted RANK expression. The ability of insulin to regulate RANK expression depends on extracellular signal-regulated kinase 1/2 (ERK1/2) since only PD98059, an ERK1/2 inhibitor, specifically inhibited its expression by insulin. However, the RANK expression by RANKL was blocked by all three mitogen-activated protein (MAP) kinases inhibitors. The activation of RANK increased differentiation of BMMs into tartrate-resistant acid phosphatase-positive ($TRAP^+$) osteoclasts as well as the expression of dendritic cell-specific transmembrane protein (DC-STAMP) and d2 isoform of vacuolar ($H^+$) ATPase (v-ATPase) Vo domain (Atp6v0d2), genes critical for osteoclastic cell-cell fusion. Collectively, these results suggest that insulin induces RANK expression via ERK1/2, which contributes to the enhancement of osteoclast differentiation.

• Microbiology and Biotechnology Letters
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• v.26 no.1
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• pp.23-33
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• 1998

The entire sequence of a 4,214,810 bp genome of the Bacillus subtilis 168 has been determined by an international project, and the completion has been announced on July 19, 1997. For the sequencing project an international consortium was established and 25 European, 7 Japanese laboratories, 2 biotechnology companies, and our laboratory participated in the project. Within this framework we determined the complete nucleotide sequence of a 53,289 bp fragment upstream of the odhA gene (181 $^{\circ}$) of the B. subtilis 168 chromosome. On the basis of the published DNA sequences of the B. subtilis sspC and odhA genes, we obtained genomic fragments by plasmid rescue and long-range PCR. The sequenced fragment contains 56 putative open reading frames (designated yojA-yolI and 9 known genes (sspC, cge cluster, orfE5, orfRMl and odhA), in which we found many interesting features. In addition, the entire nucleotide sequence of a 53,289 bp region enabled us to revise the current genetic map of this region.

• Journal of The Korean Astronomical Society
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• v.35 no.2
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• pp.105-110
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• 2002

We present the results of VLA $NH_3$ (1,1) and (2,2) line observations of the young-stellar object (YSO) IRAS 19550+3248. The integrated intensity map of the $NH_3$ (1,1) line shows that there are two ammonia cores in this region; core A which is associated with the YSO, and core B which is diffuse and located at the northeast of core A. Core A is compact and elongated along the east-west direction (0.07 pc$\times$0.05 pc) roughly perpendicular to the molecular outflow axis. Core B is diffuse and extended (0.18 pc$\times$0.07 pc). $NH_3$ (2,2) line is detected only toward core A, which indicates that it is hotter (~ 15 K), presumably due to the heating by the YSO. The $NH_3$ (1,1) line toward core A is wide (${\Delta}v{\ge} 3 km s^{-l}$) and appears to have an anomalous intensity ratio of the inner satellite hyperfine lines. The large line width may be attributed to the embedded YSO, but the hyperfine anomaly is difficult to explain. We compare the results of $NH_3$ observations with those of previous CS observations and find that the CS emission is detected only toward core A and is much more extended than the $NH_3$ emission.

• Food Science and Preservation
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• v.31 no.3
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• pp.462-473
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• 2024

The anti-inflammatory effect of beluga lentil extract (BLE) and its underlying mechanisms were investigated in lipopolysaccharide (LPS)-treated RAW 264.7 cells. Treatment with BLE significantly decreased nitric oxide (NO) production and protein and mRNA expressions of inducible NO synthase (iNOS) in LPS-treated RAW 264.7 cells. Down-regulation of this inflammatory gene expression was not associated with NF-κB/MAPK signaling pathways, and further mechanistic studies demonstrated that BLE decreased LPS-induced iNOS expression through upregulation of the nuclear factor erythroid 2-related factor 2 (Nrf2)-mediated heme oxygenase-1 (HO-1) expression. These results suggest that beluga lentil represent a potential source of natural anti-inflammatory agents, and further studies will be necessary to determine its anti-inflammatory effects in vivo.

• Korean Journal of Agricultural and Forest Meteorology
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• v.23 no.1
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• pp.34-45
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• 2021

Weather is one of the important factors in the agricultural industry as it affects the price, production, and quality of crops. Upland crops are directly exposed to the natural environment because they are mainly grown in mountainous areas. Therefore, it is necessary to provide accurate weather for upland crops. This study examined the effectiveness of 12 forest soil factors to interpolate the weather in mountainous areas. The daily temperature and precipitation were collected by the Korea Meteorological Administration between January 2009 and December 2018. The Generalized Additive Model (GAM), Kriging, and Random Forest (RF) were considered to interpolate. For evaluating the interpolation performance, automatic weather stations were used as training data and automated synoptic observing systems were used as test data for cross-validation. Unfortunately, the forest soil factors were not significant to interpolate the weather in the mountainous areas. GAM with only geography aspects showed that it can interpolate well in terms of root mean squared error and mean absolute error. The significance of the factors was tested at the 5% significance level in GAM, and the climate zone code (CLZN_CD) and soil water code B (SIBFLR_LAR) were identified as relatively important factors. It has shown that CLZN_CD could help to interpolate the daily average and minimum daily temperature for upland crops.

• Journal of Applied Biological Chemistry
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• v.65 no.2
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• pp.113-120
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• 2022

We examined the anti-inflammatory properties of Nostoc commune HCW0811 in lipopolysaccharide-stimulated RAW264.7 macrophage cells. The anti-inflammatory activity of HCW0811 on viability of treated cells was assessed by measuring the level of expression of NO, prostaglandin E₂ and pro-inflammatory cytokines, namely interleukin-1β, interleukin-6, and tumor necrosis factor-α in HCW0811 treated RAW 264.7 macrophages. HCW0811 was non-toxic to cells and inhibited the production of cytokines in a concentration-dependent manner. In addition its treatment suppressed the production of pro-inflammatory cytokines in a dose-dependent manner, and concomitantly decreased the protein expressions of inducible NO synthase and cyclooxygenase-2. Moreover, the levels of the phosphorylation of mitogen-activated protein kinase family proteins such as extracellular signal-regulated kinase, c-Jun N-terminal kinase, p38, and nuclear factor kappa B were reduced by HCW0811. These findings suggest that the HCW0811 collected from Daejeon National Cemetery have anti-inflammatory effects, and demonstrated its efficacy in cell-based in vitro assays.

• Molecular & Cellular Toxicology
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• v.5 no.3
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• pp.222-229
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• 2009

Our previous finding that pre-initiation treatment of indole-3-carbinol (I3C) represents a chemopreventive effect in dimethylbenz[a]anthracene (DMBA)-induced mammary carcinogenesis has prompted us to test the global expression of genes at an early stage. Rats were continuously fed 300 ppm I3C in their diet at 6 weeks of age and were injected with DMBA at 7 weeks of age, and were sacrificed at 8 weeks of age. Global gene expression analysis using oligonucleotide microarrays was conducted to detect altered genes in DMBA- or DMBA plus I3C-treated mammary glands. Altered genes were identified by fold changes of 1.2 and by t-test (P<0.05) from the log ratios of the hybridization intensity of samples between control (Group 1) and DMBA (Group 2), and from those of samples between DMBA (Group 2) and DMBA plus I3C (Group 3). From these genes, we chose altered genes that were up- or down-regulated by DMBA treatment and recovered to the control level by I3C treatment. For early stage of carcinogenesis, I3C treatment induced the recovery to normal levels of several genes including cell cycle pathway (cyclin B2, cell division cycle 2 homolog A), MAP signaling pathway (fibroblast growth factor receptor 1, platelet derived growth factor receptor, beta polypeptide), and insulin signaling (protein phosphatase 1, regulatory (inhibitor) subunit 3B and flotillin 2), which were up-regulated by DMBA treatment. In addition, I3C treatment induced the recovery to normal levels of several genes including those of MAPK signaling (transforming growth factor, beta receptor 1 and protein phosphatase 3, catalytic subunit, beta isoform), which were down-regulated by DMBA treatment. These results suggest that the targeting of these genes presents a possible approach for chemoprevention in DMBA-induced mammary carcinogenesis.