• Title/Summary/Keyword: M49

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Evaluation of Depth Dose and Surface Dose According to Treatment Room Wall Distance (방사선 치료실 벽면 거리에 따른 심부선량과 표층선량 평가)

  • Je, Jae-Yong
    • Journal of the Korean Society of Radiology
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    • v.5 no.3
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    • pp.121-125
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    • 2011
  • This study was intended to evaluate the surface dose and depth dose of according to the distance of the treatment room wall. High energy photon beams from linear accelerators produce large scattered radiation by various components of the treatment head, collimator and walls or objects in the treatment room including the patient. The scattered radiation measured by thermoluminescence dosimeter(TLD). Linear accelerators rotation center of the four walls(X) distance was measured to be 236, 272, 303, and 337 cm. The result of 100 cGy and 200 cGy of 6 MV photon irradiation, surface dose was 0.49, 0.83 mSv at 236 cm of the shortest distance to the wall, In 272 cm 0.41, 0.53 mSv, 303 cm in the 0.28, 0.57 mSv, and 337 cm distance from the wall in the 0.33, 0.76 mSv surface dose respectively. There was remarkable difference in the surface dose among the treatment room wall distance. The results of useful data in relation to stochastic effect for radiation therapy patients.

Properties of a Bacillus licheniformis Cellulase Produced by Recombinant Escherichia coli (대장균으로부터 생산된 Bacillus licheniformis WL-12의 Cellulase 특성)

  • Park, Jong-Duk;Kim, Yeon-A;Yoon, Ki-Hong
    • Korean Journal of Microbiology
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    • v.45 no.3
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    • pp.257-262
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    • 2009
  • Carboxymethyl celluase (cellulase) was purified from cell-free extract of the recombinant Escherichia coli carrying a Bacillus licheniformis WL-12 cellulase gene by DEAE-Sepharose and phenyl-Sepharose column chromatography with specific activity of 163 U/mg protein. The molecular mass of the purified enzyme was estimated to be approximately 49.5 kDa by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The enzyme had a pH optimum at 5.5 and a temperature optimum at $55^{\circ}C$. The activity of the enzyme was completely inhibited by SDS (5 mM), and slightly enhanced by $Cu^{2+}$ (5 mM). The cellulase was active on CMC, konjac, barely glucan and lichenan, while it did not exhibit activity towards xylan, locust bean gum, and p-nitrophenyl-$\beta$-glucopyranoside. The predominant products resulting from the cellulase hydrolysis were cellobiose and cellotriose for cellooligosaccharides including cellotriose, cellotetraose and cellopentaose. The enzyme could hydrolyze cellooligosaccharides larger than cellobiose.

Nematodes Associated with Forest Trees in Korea III. A New Species of Xiphinemella Loos, 1950, and Four Unrecorded Species of Xiphinema Cobb, 1913 (한국에 있어서 임목에 기생하는 선충조사 III. Xiphinemella 속의 1신종 및 Xiphinema속의 4미기록종에 관하여)

  • 최영연;최영식;조명래
    • Korean journal of applied entomology
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    • v.31 no.4
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    • pp.416-426
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    • 1992
  • A new species of Xiphinemella is described and illustrated from soil around the roots of larch in Korea. Xiphinemella maiensis n. sp. has stylet length of 63-68$\mu\textrm{m}$, body length of 2.5-3.2 mm, and vulva position of 49-50%. It differs from X. esseri in more posteriorly positioned vulva (42-47% in X. esseri), shorter stylet (72-75$\mu\textrm{m}$ in X. esseri), and more anteriorly located guide ring (25-27 vs. 35-38$\mu\textrm{m}$). It also differs from X. ornata in having longer body (1.94-2.32 mm in X. ornata) and shorter stylet (82-92$\mu\textrm{m}$ in X. ornata). A key to species of the genus is provided. Xiphnema brevicolle, X. diffusum, X. chambersi, and X. insigne are firstly recorded from Korea.

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Anodic Oxidation Behavior of AZ31 Magnesium Alloy in Aqueous Electrolyte Containing Various Na2CO3 Concentrations

  • Moon, Sungmo;Kim, Yeajin
    • Journal of Surface Science and Engineering
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    • v.49 no.4
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    • pp.331-338
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    • 2016
  • In this work, anodic oxidation behavior of AZ31 Mg alloy was studied as a function of $Na_2CO_3$ concentration in electrolyte by voltage-time curves and observation of surface appearances and morphologies after the anodic treatments, using optical microscopy and confocal scanning laser microscopy (CSLM). The voltage-time curves of AZ31 Mg alloy surface and surface appearances after the anodic treatments showed three different regions with $Na_2CO_3$ concentration : region I, below 0.2 M $Na_2CO_3$ where shiny surface with a number of small size pits; region II, between 0.4 M and 0.6 M $Na_2CO_3$ where dark surface with relatively low number of large size burned or dark spots; region III, more than 0.8 M $Na_2CO_3$ where bright surface with or without large size dark spots were obtained. The anodically treated AZ31 Mg alloy surface became significantly brightened with increasing $Na_2CO_3$ concentration from 0.5 M to 0.8 M which was attribute to the formation of denser and smoother surface films. Pits and porous protruding reaction products were found at relatively large size and small size spots, respectively, on the AZ31 Mg alloy surface in low concentration of $Na_2CO_3$ less than 0.2 M. The formation of pits is attributed to the result of repetition of the formation and detachment of porous anodic reaction products. Based on the experimental results obtained in this work, it is concluded that more uniform, denser and smoother surface of AZ31 Mg alloy could be obtained at more than 0.8 M $Na_2CO_3$ concentration if there is no other oxide forming agent.

Effect of Shearing Speed on High Speed Shear Properties of Sn1.0Ag0.5Cu Solder Bump on Various UBM's (다양한 UBM층상의 Sn0Ag0.5Cu 솔더 범프의 고속 전단특성에 미치는 전단속도의 영향)

  • Lee, Wang-Gu;Jung, Jae Pil
    • Korean Journal of Metals and Materials
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    • v.49 no.3
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    • pp.237-242
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    • 2011
  • The effect of shearing speed on the shear force and energy of Sn-0Ag-0.5Cu solder ball was investigated. Various UBM (under bump metallurgy)'s on Cu pads were used such as ENEPIG (Electroless Nickel, Electroless Palladium, Immersion Gold; Ni/Pd/Au), ENIG (Electroless Nickel, Immersion Gold; Ni/Au), OSP (Organic Solderability Preservative). To fabricate a shear test specimen, a solder ball, $300{\mu}m$ in diameter, was soldered on a pad of FR4 PCB (printed circuit board) by a reflow soldering machine at $245^{\circ}C$. The solder bump on the PCB was shear tested by changing the shearing speed from 0.01 m/s to 3.0 m/s. As experimental results, the shear force increased with a shearing speed of up to 0.6 m/s for the ENIG and the OSP pads, and up to 0 m/s for the ENEPIG pad. The shear energy increased with a shearing speed up to 0.3 m/s for the ENIG and the OSP pads, and up to 0.6 m/s for the ENEPIG pad. With a high shear speed of over 0 m/s, the ENEPIG showed a higher shear force and energy than those of the ENIG and OSP. The fracture surfaces of the shear tested specimens were analyzed, and the fracture modes were found to have closer relationship with the shear energy than the shear force.

The difference of photosynthetic efficiency and electron transport rate by control of the red tide organism using algicidal substance and yellow clay (살조물질과 황토를 이용한 적조생물 제어에 따른광합성 효율 및 전자전달율의 차이)

  • Son, Moonho;Baek, Seung Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.4
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    • pp.2951-2957
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    • 2015
  • The development of worldwide harmful algal blooms(HAB) is a serious problem for public health and fisheries industries. To evaluate the algicidal impact on the HAB species, algicide thiazolidinedione derivative (TD49) and yellow clay were examined, which is focus on assess the algicidal effects and inhibition to photosynthesis of HAB species. To obtain the detailed information, we analyzed the viability of target species related to activity Chl. a, photosynthetic efficiency($F_v/F_m$), and electron transport rate(ETR). Culture experiment was conducted to evaluate the algicidal effects of three harmful species(raphidophyceae Heterosigma akashiwo, Chattonella marina, and dinophyceae Heterocapsa circularisquama) and one non-harmful species (cryptophyceae Rhodomonas salina). Our experiments revealed that three HAB species were easily destroyed of the cell walls after TD49 dosing. Also, they had significantly reducing values of active Chl. a, $F_v/F_m$, and ETR, due to the damage of photosystem II by inter-cellular disturbance. As a result, the algicidal effect(%) for the three HABs were as follows, in the order of greatest to the least: H. circularisquama> C. marina> H. akashiwo. However, the algicidal effect for yellow clay remained to be <30% (p>0.01), implying that it may not have damaged the photosystem II. On the other hand, non-HAB R. salina was promoted at both TD49 and yellow clay treatments. Our results demonstrated that the TD49 is a good agent for the control of HABs H. akashiwo, C. marina, and H. circularisquama, whereas the yellow clay would not be suitable for the field application based on our experimental results.

Processing of Vermiculite-Silica Composites with Prefer-Oriented Rod-Like Pores

  • Eom, Jung-Hye;Kim, Young-Wook;Lee, Seung-Seok;Jeong, Doo-Hoa
    • Journal of the Korean Ceramic Society
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    • v.49 no.4
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    • pp.347-351
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    • 2012
  • Vermiculite-silica composites with a layered structure were fabricated by adding cellulose fibers as a pore former and by a simple uniaxial pressing and subsequent sintering process. Three different combinations of additives were used and their effects on the compressive strength and thermal conductivity of the composites were investigated. Both compressive strengths (42-128 MPa) and thermal conductivities (0.75-1.48 $W/m{\cdot}K$) in the direction perpendicular to the pressing direction (T) were higher than those (19-81 MPa and 0.32-1.04 $W/m{\cdot}K$) in the direction parallel to the pressing direction (S) in all samples. The anisotropy in both properties was attributed to the microstructural anisotropy, which was caused by the layered structure developed in the composites.

Electrically Conductive Silicon Carbide without Oxide Sintering Additives

  • Frajkorova, Frantiska;Lences, Zoltan;Sajgalik, Pavol
    • Journal of the Korean Ceramic Society
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    • v.49 no.4
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    • pp.342-346
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    • 2012
  • This work deals with the preparation of dense SiC based ceramics with high electrical conductivity without oxide sintering additives. SiC samples with different content of conductive Ti-NbC phase were hot pressed at $1850^{\circ}C$ for 1 h in Ar atmosphere under mechanical pressure of 30 MPa. The conductive phase is a mixture of Ti-NbC in weight ratio of Ti/NbC 1:4. Composite with 50% of conductive Ti-NbC phase showed the highest electrical conductivity of $30.6{\times}10^3\;S{\cdot}m^{-1}$, while the good mechanical properties of SiC matrix were preserved (fracture toughness 4.5 $MPa{\cdot}m^{1/2}$ and Vickers hardness 18.7 GPa). The obtained results show that use of NbC and Ti as sintering and also electrically conductive additives is appropriate for the preparation of SiC-based composite with sufficient electrical conductivity for electric discharge machining.

Brain somatic mutations in MTOR leading to focal cortical dysplasia

  • Lim, Jae Seok;Lee, Jeong Ho
    • BMB Reports
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    • v.49 no.2
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    • pp.71-72
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    • 2016
  • Focal cortical dysplasia type II (FCDII) is a focal malformation of the developing cerebral cortex and the major cause of intractable epilepsy. However, since the molecular genetic etiology of FCD has remained enigmatic, the effective therapeutic target for this condition has remained poorly understood. Our recent study on FCD utilizing various deep sequencing platforms identified somatic mutations in MTOR (existing as low as 1% allelic frequency) only in the affected brain tissues. We observed that these mutations induced hyperactivation of the mTOR kinase. In addition, focal cortical expression of mutant MTOR using in utero electroporation in mice, recapitulated the neuropathological features of FCDII, such as migration defect, cytomegalic neuron and spontaneous seizures. Furthermore, seizures and dysmorphic neurons were rescued by the administration of mTOR inhibitor, rapamycin. This study provides the first evidence that brain somatic activating mutations in MTOR cause FCD, and suggests the potential drug target for intractable epilepsy in FCD patients.

Cold expansion effect on the fatigue crack growth of Al 6082: numerical investigation

  • Aid, Abdekrim;Semari, Zahar;Benguediab, Mohamed
    • Structural Engineering and Mechanics
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    • v.49 no.2
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    • pp.225-235
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    • 2014
  • Cold expansion is an efficient way to improve the fatigue life of an open hole. In this paper, three finite element models have been established to bind the crack growth from an expanded hole and simulated. Expansion and its degree influence are studied using a numerical analysis. Stress intensity factors are determined and used to evaluate the fatigue life. Residual stress field is evaluated using a nonlinear analysis and superposed with the applied stresses field in order to estimate fatigue crack growth. Experimental tests are conducted under constant loading. Results of this investigation indicate expansion and its degree are beneficial to fatigue life and a good agreement was observed between FEM simulations and experimental results.