• The Journal of Korean Institute of Communications and Information Sciences
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• v.27 no.4B
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• pp.365-371
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• 2002

In this paper, the fabricated power PHEMT devices for millimeter-wave that is below a gate-length of 0.2 $\mu\textrm{m}$ using electronic beam lithography technologies, and the DC and frequency characteristics and an output power characteristics were Measured at the various bias conditions. The unit process that is used in PHEMT's manufacture used that low-resistance ohmic contact, air-bridge and back-side lapping process technologies, and so on. The fabricated power PHEMT have an S521 gain of 4 dB and a maximum transconductance(gm) of 317 mS/mm, an unilateral current gain(fT) of 62 GHz, a maximum oscillation frequency(fmax) of 120 GHz at 35 GHz, and a maximum power output(Pmax) of 16 dBm, a power gain(GP) of 4 dB and a drain efficiency(DE) of 35.5 %.

• Molecules and Cells
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• v.47 no.2
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• pp.100031.1-100031.13
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• 2024

It is now well-accepted that obesity-induced inflammation plays an important role in the development of insulin resistance and type 2 diabetes. A key source of the inflammation is the murine epididymal and human visceral adipose tissue. The current paradigm is that obesity activates multiple proinflammatory immune cell types in adipose tissue, including adipose-tissue macrophages (ATMs), T Helper 1 (Th1) T cells, and natural killer (NK) cells, while concomitantly suppressing anti-inflammatory immune cells such as T Helper 2 (Th2) T cells and regulatory T cells (Tregs). A key feature of the current paradigm is that obesity induces the anti-inflammatory M2 ATMs in lean adipose tissue to polarize into proinflammatory M1 ATMs. However, recent single-cell transcriptomics studies suggest that the story is much more complex. Here we describe the single-cell genomics technologies that have been developed recently and the emerging results from studies using these technologies. While further studies are needed, it is clear that ATMs are highly heterogeneous. Moreover, while a variety of ATM clusters with quite distinct features have been found to be expanded by obesity, none truly resemble classical M1 ATMs. It is likely that single-cell transcriptomics technology will further revolutionize the field, thereby promoting our understanding of ATMs, adipose-tissue inflammation, and insulin resistance and accelerating the development of therapies for type 2 diabetes.

• Electronics and Telecommunications Trends
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• v.28 no.2
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• pp.29-37
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• 2013

최근 임베디드 제어 시스템의 규모와 복잡도가 폭발적으로 증가함에 따라, 단일 시스템을 대상으로 하는 기존 M&S(Modeling & Simulation) 기반의 SW 개발 기술은 한계에 부딪히게 되었다. 이에 본고에서는 네트워크 기반 복합 임베디드 제어 시스템의 고신뢰 SW 개발을 위한 M&S 기술 동향을 소개한다. 먼저 모델링 단계에서 복합 시스템의 이종성을 다루기 위한 모델링 기술과 대표적인 도구를 소개하고, 다음으로 대규모 하이브리드 시스템 모델의 검증을 위한 시뮬레이션 및 정형 검증 기술과 관련 도구를 소개한다.

• Journal of Pharmaceutical Investigation
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• v.38 no.1
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• pp.15-21
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• 2008

Liposomes as one of the efficient drug carriers have some shortcomings such as their short circulation time, fast clearance from human body by reticuloendothelial system (RES) and limited intracellular uptake to target cell. In this study, polyethylenglycol (PEG)-incorporated cationic liposomes were prepared by ionic complexation of positively charged liposomes with carboxylated polyethyleneglycol (mPEG-COOH). The cationic liposomes had approximately $98.6{\pm}1.0nm$ of mean particle diameter and $42.8{\pm}0.8mV$ of zeta potential value. The PEG-incorporated cationic liposomes had $110.1{\pm}1.2nm$ of mean particle diameter with an increase of about 10 nm compared to the cationic liposomes. Zeta potential value of them was $12.9{\pm}0.6mV$ indicating 30mV decrease of cationic charge compared to the cationic liposomes. The amount of PEG which was incorporated onto the cationic liposomes was assayed by using picrate assay method and the incorporation efficiency was $58.4{\pm}1.1%$. Loading efficiency of model drug, doxorubicin, into cationic liposomes or PEG-incorporated cationic liposomes was about $96.0{\pm}0.7%$. Results of intracellular uptake which were evaluated by flow cytometry analysis of doxorubicin loaded liposomes showed that intracellular uptake of PEG-incorporated cationic liposomes was higher than the cationic liposomes or DSPE-mPEG liposomes. In addition, cytotoxicity of PEG-incorporated cationic liposomes was comparable to cationic liposomes. Consequently, the PEG-incorporated cationic liposomes of which surface was incorporated with PEG by ionic complex may be applicable as anticancer drug carriers that can increase therapeutic efficacy.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.29 no.11 s.242
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• pp.1229-1238
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• 2005

The objective of the present study was to investigate the efficacy of physical water treatment (PWT) technologies using different catalytic materials and an electronic anti-fouling device in the mitigation of mineral fouling in a once-through flow system with mini-channel heat exchanger. Effects of flow velocity and water hardness on the effectiveness of PWT technologies were experimentally studied. The artificial water hardness varied from 5.0 to 10 mo1/m$^{3}$ as CaCO$_{3}$. For 10 mo1/m$^{3}$ solution, fouling resistance reduced by 13-40$\%$ depending on flow velocity and types of PWT devices. On the other hand, fouling resistance reduced by 21-29$\%$ depending on the PWT devices for 5 mo11m3 solutions. The PWT device using alloy of Cu and Zn as catalyst (CM2) was slightly more effective than the others. SEM photographs of scale produced from the 10 mol/m$^{3}$ solution at 1.0 m/s indicated that calcium carbonate scales without PWT devices were needle-shaped aragonite, which is sticky, dense and difficult to remove. Scales with the PWT devices showed a cluster of spherical or elliptic shape crystals. Both the heat transfer test results and SEM photographs strongly support the efficacy of PWT technologies using catalytic materials and an electronic anti-fouling device in the mitigation of mineral fouling.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.3
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• pp.76-88
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• 2016

Machine to Machine (M2M) is a technology that presents communication between two or more devices with or without human intervention. M2M communications can be applied for various use cases such as environmental monitoring, health care, smart metering and etc. In most use cases, M2M utilizes sensor nodes to collect data from the intended environment and the data is transmitted back to M2M application through other devices (gateways, sink nodes). In some use cases, M2M devices are being designed to store and process sensor data for improving the reliability of the service; Gateways and sink nodes are also intended to store and process the gathered data from sensor nodes. This kind of approach is very challenging for both academy and industry. In order to enhance the performance of this approach, in this paper, we propose our Common Service Security Platform (CSSP) for M2M devices and gateways. CSSP platform presents solutions for the devices and gateways by making them operate more accurately and efficiently. Besides, we present a comparative analysis of communication protocols and present their performance in accordance with selected metrics.

• Journal of Digital Convergence
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• v.13 no.10
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• pp.343-351
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• 2015

With the diverse services of the current M2M environment being expanded to the organizations, the corporations, and the daily lives, the possibility of the occurrence of the vulnerabilities of the security of the related technologies have become an issue. In order to solve such a problem of the vulnerability of the security, this thesis proposes the technique for applying the cryptography algorithm for the protection of the device key of the M2M environment. The proposed technique was based on the elliptic curve cryptography Through the key exchange and the signature exchange in the beginning, the security session was created. And the white box cipher was applied to the encryption that creates the white box table using the security session key. Application results cipher algorithm, Elliptic Curve Cryptography provides a lightweight mutual authentication, a session key for protecting the communication session and a conventional white-box cipher algorithm and was guaranteed the session key used to encrypt protected in different ways. The proposed protocol has secure advantages against Data modulation and exposure, MITM(Man-in-the-middle attack), Data forgery and Manipulation attack.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.37B no.12
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• pp.1113-1118
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• 2012

Smart grid and intelligent transportation system draw significant interest since they are considered as one of the green technologies. These systems require a large number of sensors, actuators, and controllers. Also, machine-to-machine (M2M) communications is important because of the automatic control. The LTE-Advanced networks is preparing a set of functions that facilitate the M2M communications, and particularly the development of an efficient call admission control mechanism is critical. A method that groups MTC devices according to QoS constraints and determines the admission depending on the QoS satisfaction is limitedly applied only if the data transmission period and the maximum delay are identical. This paper proposed a call admission control that is free from such limitation and also optimizes the admission process under the certain condition of the transmission period and maximum delay. The theorems regarding the proposed method are presented with the proofs. The simulations confirms its validity and shows it is better in call admission probability than existing works.

• Environmental Engineering Research
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• v.21 no.1
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• pp.36-44
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• 2016

Constructed wetlands are established efficient technologies and provide sustainable solution for wastewater treatment. Similarly, biochar, which is an organic material, produced by means of pyrolysis, offers simple and low cost techniques to treat water and reduce carbon footprint. Combining both of these technologies can greatly augment the efficiency of the system. The objective of this study was to evaluate the efficiency of constructed wetlands by using biochar as media. Horizontal wetland beds with dimension ($1m{\times}0.33m{\times}0.3m$) were prepared using gravels and biochar, and cultivated with the Canna species. Synthetic wastewater was passed through these beds with average flow rate of $1.2{\times}10^{-7}m^3/sec$ achieving a retention time of three days. Pollutant removal performance was compared between the controlled and experimental wetland beds. This study reveals that the wetland with biochar were more efficient as compared to the wetland with gravels alone with average removal rate of 91.3% COD, 58.3% TN, 58.3% $NH_3$, 92% $NO_3-N$, 79.5% TP, and 67.7% $PO_4$.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2004.11a
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• pp.699-702
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• 2004

Next generation lithography technologies, such as EBL(Electron Beam Lithography), X-ray lithography, SPL(Scanning Probe Lithography), have been studied widely for getting over line width limitation of photolithography. Among the next generation lithography technologies, SPL has been highlighted because of its high resolution advantage. But is also has problem which are slow processing time and sample size limitation. The purpose of this study is complement of present SPL system. Brand new SPL system was made. SPL test was performed with the system in ultra thin PMMA(polymethlymethacrylate) film.