• Title/Summary/Keyword: M2M platform

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Electrogenerated Chemiluminescence Sensor Based on Tris(2,2'-bipyridyl) ruthenium(II) Immobilized in the Composite Film of Multi-walled Carbon Nanotube/Sol-gel Zinc oxide/Nafion

  • Choi, Eun-Jung;Kang, Chang-Hoon;Choi, Han-Nim;Lee, Won-Yong
    • Bulletin of the Korean Chemical Society
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    • v.30 no.10
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    • pp.2387-2392
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    • 2009
  • A composite film of multi-walled carbon nanotube (MWCNT)/sol-gel-derived zinc oxide(ZnO)/Nafion has been utilized as an efficient immobilization matrix for the construction of a highly sensitive and stable tris(2,2'-bipyridyl) ruthenium(II) (Ru(${bpy)_3}^{2+})$ electrogenerated chemiluminescence (ECL) sensor. The electrochemical and ECL behaviors of Ru(${bpy)_3}^{2+})$ ion-exchanged into the composite film were strongly dependent upon the sol-gel preparation condition, the amount of MWCNT incorporated into the ZnO/Nafion composite film, and the buffer solution pH. The synergistic effect of MWCNTs and ZnO in the composite films increased not only the sensitivity but also the long-term stability of the ECL sensor. The present ECL sensor based on the MWCNT/ZnO/Nafion gave a linear response ($R^2$ = 0.999) for tripropylamine concentration from 500 nM to 1.0 mM with a remarkable detection limit (S/N = 3) of 15 nM. The present ECL sensor showed outstanding long-term stability (94% initial signal retained for 5 weeks). Since the present ECL sensor exhibits large response towards NADH, it could be applied as a transduction platform for the ECL biosensor in which the NADH is produced from the dehydrogenase-based enzymatic reaction in the presence of NA$D^+$ cofactor.

Geomorphic Development of Marine Terraces at Jeongdongjin-Daejin area on the East Coast, Central Part of Korean Peninsula (한반도 중부 동해안 정동진, 대진지역의 해안단구 지형발달)

  • 윤순옥;황상일;반학균
    • Journal of the Korean Geographical Society
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    • v.38 no.2
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    • pp.156-172
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    • 2003
  • In this paper we identify that there are High Higher surfaces(HH-surface) around Jeongdongjin and Daejin area where Higher surfaces(H-surface) of marine terrace are formed on a large scale. On the basis of an altitude of the ancient shoreline of the marine terraces, geomorphic surfaces can be classified into HH I (140m a.s.l), HH II (110m a.s.l), H I (90m a.s.l), H II (70m a.s.l), M (40m a.s.l), L I (25m a.s.l) and L II (10m a.s.l). Besides, we identify that the lowest surfaces(5~6m a.s.l) are found extensively in the research area which are assumed to be formed in the Holocene. Considering that the formation mechanism of the marine terraces in the research area is similar to that of the marine terraces at both Campo area in the south east coastal region of Korea md the thalassostatic terraces of Osip River in Samchuk in a short distance from the research area, we can assume that the HH-surfaces in both areas were formed in the same period. Based on the fact that L I- surface was formed on the Last Interglacial Stage of MIS 5, we can infer that M- was formed in MIS 7, H I- in MIS 9, H II- in MIS 11, HH I- in MIS 13 and HH II- in MIS 15. The reason for that H-surfaces, similar to those at Gampo area, to remain on a large scale is that the Holsteinian Interglacial continued for a long period of time and at that time there was a large wave-cut platform in the vicinity of the shoreline.

Novel Resectable Myocardial Model Using Hybrid Three-Dimensional Printing and Silicone Molding for Mock Myectomy for Apical Hypertrophic Cardiomyopathy

  • Wooil Kim;Minje Lim;You Joung Jang;Hyun Jung Koo;Joon-Won Kang;Sung-Ho Jung;Dong Hyun Yang
    • Korean Journal of Radiology
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    • v.22 no.7
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    • pp.1054-1065
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    • 2021
  • Objective: We implemented a novel resectable myocardial model for mock myectomy using a hybrid method of three-dimensional (3D) printing and silicone molding for patients with apical hypertrophic cardiomyopathy (ApHCM). Materials and Methods: From January 2019 through May 2020, 3D models from three patients with ApHCM were generated using the end-diastolic cardiac CT phase image. After computer-aided designing of measures to prevent structural deformation during silicone injection into molding, 3D printing was performed to reproduce anatomic details and molds for the left ventricular (LV) myocardial mass. We compared the myocardial thickness of each cardiac segment and the LV myocardial mass and cavity volumes between the myocardial model images and cardiac CT images. The surgeon performed mock surgery, and we compared the volume and weight of the resected silicone and myocardium. Results: During the mock surgery, the surgeon could determine an ideal site for the incision and the optimal extent of myocardial resection. The mean differences in the measured myocardial thickness of the model (0.3, 1.0, 6.9, and 7.3 mm in the basal, midventricular, apical segments, and apex, respectively) and volume of the LV myocardial mass and chamber (36.9 mL and 14.8 mL, 2.9 mL and -9.4 mL, and 6.0 mL and -3.0 mL in basal, mid-ventricular and apical segments, respectively) were consistent with cardiac CT. The volume and weight of the resected silicone were similar to those of the resected myocardium (6 mL [6.2 g] of silicone and 5 mL [5.3 g] of the myocardium in patient 2; 12 mL [12.5 g] of silicone and 11.2 mL [11.8 g] of the myocardium in patient 3). Conclusion: Our 3D model created using hybrid 3D printing and silicone molding may be useful for determining the extent of surgery and planning surgery guided by a rehearsal platform for ApHCM.

CFD ANALYSIS OF DISTRIBUTION OF AIR TEMPERATURE ON PLATFORMS OF A LARGE RAILWAY STATION IN SUMMER SEASON

  • Tsukamoto Kenji;Iino Akinaru;Tominaga Yoshihide
    • Proceedings of the KSRS Conference
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    • 2005.10a
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    • pp.173-177
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    • 2005
  • The purpose of this study is to analyze the principal causes of increases in air temperature on platforms of railway station. We analyzed the distribution of air temperature on Shinkansen platforms at Station 'A' using Computational Fluid Dynamics (CFD). We focused on the factors that influence the temperature dynamics associated with heat generated by trains and station buildings and their effect on the ambient temperature on platforms. In the case of heat generated by trains, air temperature on Shinkansen platforms increased by 4 to 7 degrees compared to when trains generated no heat. When a 50-m high station building was located on the windward side of the platforms, air temperature on Platform X was 2 degrees higher than when the station buildings were absent. Air? temperature on platforms VII to IX increased progressively, and the maximum air temperature on platform VIII was 3 K higher than if station buildings were absent.

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Open Loop Responses of Posture Complexity in Biomechanics

  • Shin, Youngkyun;Park, Gu-Bum
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.27 no.8
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    • pp.42-50
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    • 2013
  • The reactionary responses to control human standing dynamics were estimated under the assumption that postural complexity mainly occurs in the mid-sagittal plane. During the experiment, the subject was exposed to continuous horizontal perturbation. The ankle and hip joint rotations of the subject mainly contributed to maintaining standing postural control. The designed mobile platform generated anterior/posterior (AP) motion. Non-predictive random translation was used as input for the system. The mean acceleration generated by the platform was measured as $0.44m/s^2$. The measured data were analyzed in the frequency domain by the coherence function and the frequency response function to estimate its dynamic responses. The significant correlation found between the input and output of the postural control system. The frequency response function revealed prominent resonant peaks within its frequency spectrum and magnitude. Subjects behaved as a non-rigid two link inverted pendulum. The analyzed data are consistent with the outcome hypothesized for this study.

A Numerical Study on the Smoke Control in Side-Platform Type Subway Station Fires (상대식 지하철 역사내 화재시 연기제어에 관한 수치해석적 연구)

  • Lee, Sung-Ryong;Ryou, Hong-Sun
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.20 no.2
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    • pp.81-86
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    • 2008
  • In this study, numerical simulations were carried out to analyze the effect of the smoke extraction system and fire shutters in subway station fires using FDS 4.0. Subway station used in the experiment was 205 m long. Simulation results are validated by comparing with experimental results. Simulation results showed good agreement with experimental results within $20\;^{\circ}C$. 20 MW polystyrene was used as a fuel in the numerical prediction. Numerical predictions were performed in the side-platform type subway station in case of a train fire. Temperature and CO concentration were lowered by the operation of smoke extraction system.

Citic Tower Construction Key Technology

  • Xu, Lishan
    • International Journal of High-Rise Buildings
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    • v.8 no.3
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    • pp.185-192
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    • 2019
  • Citic Tower is the first over-500 m-tall super highrise building in the world, located in the high seismic intensity area with paek ground acceleration over 0.2g in 475 years. This project is unique in its complexity, large volume, and challenging site conditions (zero site for construction). The traditional techniques can hardly meet safty, quality and schedule requirements of the construction. This article introduces the key construction technologies that are innovatively developed and applied in Citic Tower project construction, including intelligent super-high-rise building integrated construction platform system, independently developed by the CCTEB; Jump-Lift Elevator, which is the first of the kind with service height over 500 meters; combined temporary-and-permanent fire protection systems. The BIM technology is also applied in this project. Through technical innovation, and utilization of technologies, construction speed and safety had been greatly improved.

Microarray Analysis of Alteration in Gene Expression by Acori graminei rhizoma (AGR) Water-Extract in a Hypoxic Model of Cultured Rat Cortical Cells (흰쥐 대뇌세포의 저산소증 모델에서 석창포(石菖浦 Acori graminei rhizoma. AGR)에 의한 유전자 표현 변화의 microarray 분석)

  • Park, Dong-Jun;Jung, Seung-Hyun;Moon, Il-Soo;Lee, Won-Chol;Shin, Gil-Jo
    • Journal of Life Science
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    • v.17 no.1 s.81
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    • pp.150-161
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    • 2007
  • Acori graminei Rhizomn (AGR) is a perennial herb which has been used clinically as a traditional oriental medicine against stroke, Alzheimer's disease, and vascular dementia. We investigated the effect of AGR on the modulation of gene expression profile in a hypoxic model of cultured rat cortical cells. Rat cerebrocortical cells were grown in Neurobasal medium. On DIV12, cells were treated with AGR $(10ug/m\ell)$, given a hypoxic shock (2% $O_2$, 3 hr) on DIV14, and total RNAs were prepared one day after shock. Microarray analyses indicated that the expression levels of most genes were altered within the global M values +0.5 and -0.5, i.e., 40% increase or decrease. There were 750 genes which were upregulated by < global M +0,2, while 700 genes were downregulated by > global M -0.2. The overall profile of gene expression suggests that AGR suppresses apoptosis (upregulation of anti-apopotic genes such as TEGT, TIEG, Dad, p53, and downregulation of pro-apopotic genes such as DAPK, caspase 2, pdcd8), ROS (upregulation of RARa, AhR), and that AGR has neurotrophic effects (upregulation of Aktl, Akt2). These results provide a platform for investigation of the molecular mechanism of the effect of AGR in neuroprotection.

Assessment of Airborne Bacteria and Particulate Matters Distributed in Seoul Metropolitan Subway Stations (서울시 일부 지하철역 내 분포하는 부유 세균 및 입자상 오염물질 평가)

  • Kim, Ki-Youn;Park, Jae-Beom;Kim, Chi-Nyon;Lee, Kyung-Jong
    • Journal of Environmental Health Sciences
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    • v.32 no.4 s.91
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    • pp.254-261
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    • 2006
  • In activity areas of subway workers and passengers in Seoul metropolitan subway lines 1-4, mein concentrations of airborne bacteria were relatively higher in workers' bedroom and station precinct whereas concentrations of particulate matters, $PM_{10}$ and $PM_{2.5}$, were relatively higher in platform, inside train and driver's seat as compared with other activity areas. This result indicates that little correlation between airborne bacteria and particulate matters was found, which assumed that most airborne particulate matters distributed in subway consisted of mainly inorganic dust like a metal particles. Mean concentrations of $PM_{10}$ and $PM_{2.5}$ in station precinct and platform exceeded the threshold limit value ($PM_{10}:150{\mu}g/m^3,\;PM_{2.5}:65{\mu}g/m^3$) but those in station office and ticket office were below it. The genera identified in all the activity areas of subway over 5% detection rate were Staphylococcus, Micrococcus, Bacillus and Corynebacterium, of which Staphylococcus and Micrococcus covered over 50% of total airborne bacteria and were considered as predominant genera distributed in subway.

Investigation for Fire Flow of the Deeply Underground Shin-Gum-Ho Subway Station (대심도 신금호역사의 화재 유동에 대한 고찰)

  • Jang, Yong-Jun;Park, Il-Soon;Kim, Jin-Ho;Jung, Woo-Sung;Kim, Hag-Beom;Lee, Chang-Hyun
    • Proceedings of the KSR Conference
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    • 2010.06a
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    • pp.110-115
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    • 2010
  • Recently the deeply underground tunnels have been increased along the subway railroads of urban area compared to the past subway railroads. The Shin-Gum-Ho subway station (the Fifth lines, the depth : 46m) which is the third among the deep subway stations in the Korea was chosen as the model of deeply underground stations, and attempted to do simulation of fire. This station consists of three entrance, the basement first floor (B1), the basement second floor (B2), the basement eighth floor or platform (B8) and escalators and stairs from B2 to B8. The total number of grid was about 9,000,000 to make simulation of fire and smoke from the platform to entrance in this research, and the grid system was divided into 19 blocks to increase the efficiency of this simulation. The FDS (Fire Dynamics Simulation) was chosen to make the simulation of fire, and the model of turbulent flow was LES (Large Eddy Simulation). Each block is processed in a CPU using parallel processing of MPI (Message Passing Interface). The resource of CPU for this simulation is a ten of Intel 3.0 GHz Dual CPU (20 CPU).

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