• Title/Summary/Keyword: M1 polarization

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Improvement of Corrosion Resistance for Copper Tube by Electrochemical Passivation (전기화학적 부동태화에 의한 동관의 내식성 개선 연구)

  • Min, Sung-Ki;Kim, Kyung-Tae;Hwang, Woon-Suk
    • Corrosion Science and Technology
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    • v.10 no.4
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    • pp.125-130
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    • 2011
  • This study was performed to improve the corrosion resistance and the stability of passive film on copper tube by potentiostatic polarization method in synthetic tap water. Formation of passive film was carried out by anodic potentiostatic polarization at various passivation potentials and passivation times in 0.1 M NaOH solution. Stability of passive film and corrosion resistance was evaluated by self-activation time, ${\tau}_0$ from passive state to active state on open-circuit state in 0.1 M NaOH solution. Addition of polyphosphate in NaOH solution prolonged the self-activation time and improved the corrosion resistance, and the addition of 5 ppm polyphosphate was most effective. It was also observed that better corrosion resistance was obtained by potentiostatic polarization at 1.0 V (vs. SCE) than at any other passivation potentials. Passivated copper tube showed perfect corrosion resistance for the immersion test in synthetic tap water showing that the anodic potentiostatic polarization treatment in 0.1 M NaOH with 5 ppm polyphosphate solution would be effective in improving the corrosion resistance and preventing the blue water problem.

Time dependent polarization switching properties of injection-locked 1.55-${\mu}m$ VCSEL

  • Deshmukh, Vijay Manohar;Lee, Seoung-Hun;Lee, Min-Hee;Kim, Dong-Wook;Kim, Kyong-Hon
    • Proceedings of the Optical Society of Korea Conference
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    • 2009.10a
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    • pp.359-360
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    • 2009
  • This paper reports experimental results on temporal characteristics of injection-locked polarization switching of a conventional type 1.55-${\mu}m$ wavelength single-mode vertical-cavity surface-emitting laser (VCSEL). The polarization of external injection beam was kept orthogonal to main mode of VCSEL. The relation for variation of intensity of two polarization modes of VCSEL with wavelength detuning for various repetition rates of injection pulse is reported.

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Investigation of some Natural Product Extracts as Corrosion Inhibitors for Mild Steel in Acid Mediu

  • Subramania, A.;Sathiya Priya, A.R.;Saravanan, S.;Abdul Nasser, A.J.;Vasudevan, T.
    • Corrosion Science and Technology
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    • v.4 no.6
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    • pp.231-235
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    • 2005
  • The inhibitive effect of extracts of tamarind seeds and jackfruit seeds, curry leaves and henna leaves on corrosion of mild steel in 1M HCl solution have been studied by weight loss, potentiodynamic polarization and impedance measurements. Results obtained from the electrochemical techniques were in good agreement with weight loss results. From the weight loss data, the values of surface coverage ($\Theta$) and corrosion rate were calculated. The inhibition efficiency (IE) increased with increasing inhibitor concentration in 1M HCl solution. In all the cases the adsorption of the natural product extracts on the mild steel surface from 1M HCl follows the Langmuir adsorption isotherm relationship. Potentiodynamic polarization studies reveal the fact that all the four natural product extracts act as mixed type inhibitors. The decrease in the inhibition efficiency follows the order: Extracts of jackfruit seed>henna leaves>curry leaves>tamarind seed.

Ginsenoside Rg3 promotes inflammation resolution through M2 macrophage polarization

  • Kang, Saeromi;Park, Soo-Jin;Lee, Ae-Yeon;Huang, Jin;Chung, Hae-Young;Im, Dong-Soon
    • Journal of Ginseng Research
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    • v.42 no.1
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    • pp.68-74
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    • 2018
  • Background: Ginsenosides have been reported to have many health benefits, including anti-inflammatory effects, and the resolution of inflammation is now considered to be an active process driven by M2-type macrophages. In order to determine whether ginsenosides modulate macrophage phenotypes to reduce inflammation, 11 ginsenosides were studied with respect to macrophage polarization and the resolution of inflammation. Methods: Mouse peritoneal macrophages were polarized into M1 or M2 phenotypes. Reverse transcription-polymerase chain reaction, Western blotting, and measurement of nitric oxide (NO) and prostaglandin $E_2$ levels were performed in vitro and in a zymosan-induced peritonitis C57BL/6 mouse model. Results: Ginsenoside $Rg_3$ was identified as a proresolving ginseng compound based on the induction of M2 macrophage polarization. Ginsenoside $Rg_3$ not only induced the expression of arginase-1 (a representative M2 marker gene), but also suppressed M1 marker genes, such as inducible NO synthase, and NO levels. The proresolving activity of ginsenoside $Rg_3$ was also observed in vivo in a zymosan-induced peritonitis model. Ginsenoside $Rg_3$ accelerated the resolution process when administered at peak inflammatory response into the peritoneal cavity. Conclusion: These results suggest that ginsenoside $Rg_3$ induces the M2 polarization of macrophages and accelerates the resolution of inflammation. This finding opens a new avenue in ginseng pharmacology.

Regulation of alternative macrophage activation by MSCs derived hypoxic conditioned medium, via the TGF-β1/Smad3 pathway

  • Kim, Ran;Song, Byeong-Wook;Kim, Minji;Kim, Won Jung;Lee, Hee Won;Lee, Min Young;Kim, Jongmin;Chang, Woochul
    • BMB Reports
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    • v.53 no.11
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    • pp.600-604
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    • 2020
  • Macrophages are re-educated and polarized in response to myocardial infarction (MI). The M2 anti-inflammatory phenotype is a known dominator of late stage MI. Mesenchymal stem cells (MSCs) represent a promising tool for cell therapy, particularly heart related diseases. In general, MSCs induce alteration of the macrophage subtype from M1 to M2, both in vitro and in vivo. We conjectured that hypoxic conditions can promote secretome productivity of MSCs. Hypoxia induces TGF-β1 expression, and TGF-β1 mediates M2 macrophage polarization for anti-inflammation and angiogenesis in infarcted areas. We hypothesized that macrophages undergo advanced M2 polarization after exposure to MSCs in hypoxia. Treatment of MSCs derived hypoxic conditioned medium (hypo-CM) promoted M2 phenotype and neovascularization through the TGF-β1/Smad3 pathway. In addition, hypo-CM derived from MSCs improved restoration of ischemic heart, such as attenuating cell apoptosis and fibrosis, and ameliorating microvessel density. Based on our results, we propose a new therapeutic method for effective MI treatment using regulation of macrophage polarization.

A Study on the Post-Weld Heat Treatment Effect Affecting Corrosion Behavior and Mechanical Property of Welding Part of RE36 Steel for Marine Structure (해양구조물용 RE36강 용접부의 부식거동 및 기계적 특성에 미치는 용접후 열처리 효과에 관한 연구)

  • 김성종;문경만
    • Journal of Welding and Joining
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    • v.19 no.1
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    • pp.65-74
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    • 2001
  • A study on the corrosion behavior in case of As-welded and PWHT temperature 55$0^{\circ}C$ of welding part of RE36 steel for marine structure was investigated with parameters such as micro-Vickers hardness, corrosion potential measurement of weld metal(WM), base metal(BM) and heat affected zone(HAZ), both Al anode generating current and Al anode weight loss quantity under sacrificial anode cathodic protection conditions. And also we carried out slow strain rate test(SSRT) in order to research both limiting cathodic polarization potential for hydrogen embrittlement and optimum cathodic protection potential as well as mechanical properties by post-weld heat treatment(PWHT) effect. Hardness of HAZ was the highest among three parts(WM, BM and HAZ) and the highest galvanic corrosion susceptibility was HAZ. And the optimum cathodic polarization potential showing the best mechanical properties by SSRT method was from -770mV to -875mV(SCE). In analysis of SEM fractography, applied cathodic potential from -770mV to -875mV(SCE) it appeared dimple pattern with ductile fracture while it showed transgranular pattern (Q. C : quasicleavage) under -900mV(SCE). However it is suggested that limiting cathodic polarization potential indicating hydrogen embrittlement was under -900mV(SCE).

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The Study on the Electrochemical Polarization Characteristics of Hydrogen Embrittlement for Ferrite Stainless Steel with Welding Conditions (용접조건에 따른 페라이트 스테인리스강에 대한 수소취성의 전기화학적 분극특성에 관한 연구)

  • Choi, Byung-Il;Lim, Uh-Joh
    • Journal of the Korean Institute of Gas
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    • v.9 no.4 s.29
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    • pp.30-35
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    • 2005
  • In order to examine the electrochemical polarization characteristics of hydrogen embrittlement far STS444 with welding conditions, this paper carried out the accelerated hydrogen osmosis test and the electrochemical polarization test. That is, in $0.5M\; H_2SO_4+0.001M\;As_2O_3$ solution, the hydrogen embrittlement behavior of STS444 added to load of $1,400kg/cm^2$ together with hydrogen osmosis by current of $30mA/cm^2$ far 60 min. was considered. In researching the electrochemical polarization characteristics of hydrogen embrittlement for STS444 with welding conditions, the previous study clarified that tensile strength or elongation became low influenced by absorption of oil or water before welding. In this paper, we proposed the advanced mechanism of hydrogen embrittlement that integrated electrochemical corrosion with the existing mechanism of hydrogen embrirtlement.

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A Study on the Concentration Polarization Layer Resistance in Ultrafiltration of Macromolecular Solutions (고분자 용액의 한외여과에서 농도분극층 저항에 관한 연구)

  • 염경호
    • Membrane Journal
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    • v.2 no.1
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    • pp.59-66
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    • 1992
  • The experimental studies were carried out on ultrafiltration of PEG #6000 and dextran 70T macromole¬cules. using an asymmetric cellulose acetate membrane in a cross flow plane type cell. Effects of pressure difference. feed concentration were studied on permeate flux and observed rejection for both the macromole¬cules. and the concentration polarization layer resistance $R_{b1}$ on permeate flux was analysed. The concentration polarization layer resistance $R_{b1}$ was correlated with the average macromolecule concen¬tration $C_{b1}$ in polarization layer. The resulting dimensionless correlation was expressed as : $\frac{R_{b1}}{{R_m}}=\alpha[\frac{\rho_{b1}}{C_{b1}}]^\beta$

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1.55 μm polarization mode splitter utilizing two mode interference of Ti:LiNbO3 optical waveguides (1.55 μm Ti:LiNbO3 광도파로의 두 모드 간섭을 이용한 편광모드 분리기)

  • 김정희;정기조;정홍식;이한영
    • Korean Journal of Optics and Photonics
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    • v.13 no.1
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    • pp.32-37
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    • 2002
  • Passive polarization mode splitters at λ= 1.55 ${\mu}{\textrm}{m}$ were designed and fabricated based on Ti:x-cut LiNbO$_3$ single-mode optical waveguide and two-mode interference theory. The splitting ratio with waveguide width 8 ${\mu}{\textrm}{m}$, branching angle 0.55$^{\circ}$ and interfering length 470 ${\mu}{\textrm}{m}$ showed 16.18 dB, 21.25 dB for TE and TM input polarization modes, respectively. Polarization cross-talk of -16.28 dB and -21.28 dB for TE and TM modes was achieved. Total insertion losses of 2.24 dB/cm (TE) and 2.41 dB/cm (TM) were also measured. The devices operated nearly wavelength independently over a range or 30 nm.

Phellinus linteus Extract Regulates Macrophage Polarization in Human THP-1 Cells (상황버섯 추출물의 인간 유래 THP-1 단핵구 세포주의 분극화 조절)

  • Lee, Sang-Yull;Park, Sul-Gi;Yu, Sun-Nyoung;Kim, Ji-Won;Hwang, You-Lim;Kim, Dong-Seob;Ahn, Soon-Cheol
    • Journal of Life Science
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    • v.30 no.2
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    • pp.113-121
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    • 2020
  • Macrophages are initiators for regulating a host's defenses to eliminate pathogens and trigger tissue repair. Macrophages are classified into two types: classically (M1) activated macrophages and alternatively (M2) activated macrophages. M1-phenotype macrophages directly or indirectly kill infectious organisms and tumor cells via pro-inflammatory responses, whereas M2-phenotype macrophages remodel wounded tissue through anti-inflammatory responses. In this paper, we investigated how Phellinus linteus hot water extract passed from Diaion HP-20 resin (PLEP) regulates polarization of M1-like or M2-like macrophages in human THP-1 cells. PLEP did not have cytotoxicity at a high concentration of 300 ㎍/ml. We observed morphological alteration of the THP-1 cells, which are stimulated by PLEP, LPS/INF-γ (M1 stimulators) or IL-4/IL13 (M2 stimulators). PLEP exposure induced morphology contiguous with LPS/INF-γ. qPCR was also performed to determine whether PLEP influences M1 or M2 polarization-related genes. M1-phenotype macrophage-specific genes, such as TNF-α, IL-1β, IL-6, IL-8, CXCL10 and CCR7, were enhanced by PLEP in a dose-dependent manner similar to LPS/INF-γ. Conversely, M2-phenotype-specific genes, such as MRC-1, DC-SIGN, CCL17 and CCL22, were suppressed by PLEP. PLEP also significantly up-regulated secretory inflammation cytokines related to M1 polarization of macrophages, including TNFα, IL-1β and IL-6, which was similar to the gene expression. Further, MAPK and NF-κB signaling were increased by treatment with PLEP, resulting in enhancement of cytokine secretion. PLEP might therefore be used as a promising booster of pro-inflammatory responses through M1 polarization of human THP-1 cells.