• Biomolecules & Therapeutics
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• v.23 no.3
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• pp.238-244
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• 2015

Macrophage-derived chemokine, C-C motif chemokine 22 (MDC/CCL22), is one of the inflammatory chemokines that controls the movement of monocytes, monocyte-derived dendritic cells, and natural killer cells. Serum and skin MDC/CCL22 levels are elevated in atopic dermatitis, which suggests that the chemokines produced from keratinocytes are responsible for attracting inflammatory lymphocytes to the skin. A major signaling pathway in the interferon-${\gamma}$ (IFN-${\gamma}$)-stimulated inflammation response involves the signal transducers and activators of transcription 1 (STAT1). In the present study, we investigated the anti-inflammatory effect of dieckol and its possible action mechanisms in the category of skin inflammation including atopic dermatitis. Dieckol inhibited MDC/CCL22 production induced by IFN-${\gamma}$ (10 ng/mL) in a dose dependent manner. Dieckol (5 and $10{\mu}M$) suppressed the phosphorylation and the nuclear translocation of STAT1. These results suggest that dieckol exhibits anti-inflammatory effect via the down-regulation of STAT1 activation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.7
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• pp.4237-4245
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• 2014

In this study, products in a B2B online shopping mall were classified efficiently using DEA, and an operational process is presented. The results using the data of M company were used to calculate the workload according to the category. The work load of managing the product using the DEA has been distributed evenly. In addition, the classification of A is composed of the highest net income, and it was intended to be managed centrally by the company. Business classifications C and B, which were made of a low severity workload, were reduced. Therefore, efficient operation is possible when applied to an actual business.

• Asian-Australasian Journal of Animal Sciences
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• v.10 no.2
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• pp.192-195
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• 1997

Thirty adults Desi and Khaki Campbell ducks were distributed to 6 farmers of Chakcharpur village of Mymensingh district. These ducks were subjected 3 types of mating e.g. Desi ${\times}$ Desi, Khaki Campbell ${\times}$ Khaki Campbell and Khaki Campbell ${\times}$ Desi-having 10 ducks (male : female = 1 : 4) in each mating group. Each mating group was then divided into two having 5 ducks(male : female = 1 : 4) and distributed to 2 farmers. After collecting eggs from each mating category, these were hatched by broody hens from which a total of 90 day old ducklings, 30 from each genotype were raised from birth to 90 days after the onest of laying. Although the weight of the day old chicks were similar in all genotypes (40-43 g), body weight was the highest (p <0.01) for Khaki Campbell ${\times}$ Desi (1,543) before the onset of laying followed by Khaki Campbell (1,552 g) and Desi (1,448 g) ducks. Khaki Campbell attained maturity at an earlier (p < 0.01) age (147 days) followed by Khaki Campbell ${\times}$ Desi, (154 days) and Desi (161 days) ducks. Khaki Campbell laid maximum (p < 0.01) number of eggs (46) compared to Khaki Campbell ${\times}$ Desi, (30) and Desi (18) ducks 90 days after the onset of laying. However, eggs were heavier (p < 0.01) in Desi (61.9) ducks compared to other genotypes. Fertility and hatchability were also higher in Desi ducks than the other two genotypes. Mortality was also lover in Desi ducks (3.33%) followed by Khaki Campbell ${\times}$ Desi (6.66%) and Khaki Campbell (16.66%) ducks. The results presented here indicated the superiority of Desi ducks over the other two genotypes with respect to egg weight, fertility, hatchability and mortality under village condition. Pure and crossbreds, on the other hand, were heavier at sexual maturity at relatively younger age and laid more eggs.

• Journal of Nutrition and Health
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• v.36 no.7
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• pp.769-776
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• 2003

This study has analyzed the association of physical activity and television watching time with obesity in 30-50 aged women from middle income town in Busan city area. Data were obtained using a questionnaire, including information about physical activity, TV watching time and health habit; social data regarding educational level and monthly income; family history of chronic condition. Height and weight were measured. Outcome variable was obesity, defined as a body mass index 25 kg/m$^2$ or greater. Odds ratios (OR) for obesity were estimated by multivariate logistic regression, and interpreted as a relative risk of obesity. The prevalence of obesity was 11.8%. The mean BMI of obese women was 26.9 kg/m$^2$. The OR of obesity was higher in subject of 40s than 30s. Subjects who had higher educational level presented lower OR than those of elementary or middle school education. Family income was not associated with obesity. Women having a family history of chronic condition had higher risk of obesity than those who did not have it. The OR was lower in active people at work (OR = 0.51; 95% CI = 0.26 - 0.98) than in inactive ones, and the ORs associated with regular exercise or activity at leisure time were not statistically different. However, subjects watching TV $\geq$ 3.5 hr/day showed higher OR (OR = 2.34; 95% CI = 1.16 - 4.74), compared with those watching TV $\geq$ 1.5 hr/day. Association of the joint classification of physical activity variables with obesity was estimated. The highest relative risk of 5.99 was in women in physically inactive at work and high category of TV watching ($\geq$ 3.5 hr/day). Even in women in active at work, the watching TV $\geq$ 3.5 hr/day made them have the high OR (OR = 2.44; 95% CI = 1.03 - 5.77). And at each time level of TV watching, the increasing activity level at work was associated with lower OR for obesity. These findings suggest that both TV watching time and physical activity at work were related to obesity in adult female, each with independent effects on obesity. TV watching time seems to be a significant factor that could partly evaluate the energy expenditure.

• Journal of the Korea Society of Computer and Information
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• v.17 no.1
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• pp.117-123
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• 2012

The purpose of this study is to design and develop the e-mentoring system which supports the effective information education and to evaluate the usability of the system. Through literature reviews of related studies, an effective e-mentoring performance model was drawn. An e-mentoring system was designed and developed based on the model. 237 middle school students who had participated in e-mentoring for the information education evaluated the usability of the system. As a result of it, the system was considered good in both category(supporting mentoring(M=3.63), technology(M=3.78). The means of subcategories of 'supporting mentoring'(instructional easiness, psychological safety, and adaptability) were scored 3.65, 3.30, 3.43 respectively. And means in the subcategories of 'technology'(usefulness, accuracy, and look & feel) were 3.90, 3.64, and 3.73. It can be concluded that the e-mentoring system developed in this study was effective in mentoring information education.

• KIEAE Journal
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• v.17 no.3
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• pp.15-21
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• 2017

Purpose: "Building energy design standard" is used to limit the thermal transmittance of building in Korea. However, it only covers the insulation standard for each appropriate elements of a building, not the thermal performance of Junction thermal bridge of windows and doors installed in wall. Therefore in this study, we have evaluated the thermal performance of Junction thermal bridge depending on installation method and position of windows and provide it as design data. Method: We analyzed heat transfer of 4-Track sliding window and tilt & turn triple glazed window that are placed in the first class category on window energy efficiency rating using Window 7.4 and Therm 7.4. Result : First, linear thermal transmittance of 4-Track sliding window differs by 2.2 times or more depending of installation method and location. It is higher than the linear thermal transmittance, 0.01W/mK, proposed by Passivhaus. Second, linear thermal transmittance of Tilt & turn triple glazed window differs by 7.7 times or more depending of installation method and location. The average linear thermal transmittance was less than 0.01W /mK when windows were installed on the internal wall insulation by the fixed hardware attachment method. Third, the thermal losses of a window caused by a junction thermal bridge are inversely proportional to the window area and converge gradually as the area increased.

• The Journal of Korean Academic Society of Nursing Education
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• v.10 no.1
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• pp.75-83
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• 2004

This study was conducted to examine the ethical dilemma and coping types of nurses, and identify the relationship between ethical dilemma and coping types of nurses. The subjects of this study consisted of 210 nurses from two university hospitals in Taegu and one university hospital and one general hospital in Pohang. The data were collected with self reported questionnaire from June 2003 to July 2003. The data were analysed using the SPSS program. The results of this study were as follows : 1. The mean score of level of ethical dilemma was 0.55/1, and client area was the highest(M=0.65). 2. The mean score of level of coping about ethical dilemma was 2.22/4, and seeking social support area was the highest (M=2.42). 3. The conflict of proffering the best care with courtesy to impolite patient was the highest in total items of ethical dilemma. Criticized or lectured myself was the highest in total items of coping type. 4. In general characteristics, age(F=4.74, p<.01), marital status(t=2.67, p<.01), career (F=5.95, p<.01) were significantly related to level of ethical dilemma and religion(t=2.27, p<.05) was significantly related to types of coping. There was positive correlation between ethical dilemma and types of coping(r=.228, p<.01). On the basis of these findings, it is needed a correlation study according to category of ethical dilemma and coping types of nurses, and to develop the coping strategy that resolves ethical dilemma in nursing practice.

• 산업보건소식
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• no.46
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• pp.3-13
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• 1987

For the purpose of investigating the effect of occupational health service in terms of environmental control and health provision of workers on the improvement of worker's health, authors analysed the data of environmental measurement and health check-up of one lead using industry who started his investment to environmental improvement from 1980. Six hundred million won was invested for environmental improvement from 1980 to 1986. This investment brought about apparent improvement of working conditions of all of the workplaces from mean concentration of lead in air over 0.15mg/$m^3$ 1981 to mean concentration of lead in air less than 0.15mg/$m^3$. Environmental control reduced mean blood lead level from 51.2 $\pm$ 11.5ug/이 in 1983 to 39.2 $\pm$ 16.0ug/dl in 1986, and delta-aminolevulinic acid concentration 3.15 $\pm$ 2.1mg/l in 1982 to 1.96 $\pm$ 1. 7mg/l in 1986, respectively. Blood ZPP levels were decreased from 76.1 $\pm$ 58.9ug/dl in 1983 to 42.23 $\pm$ 30.3ug/dl in 1986. If 150ug/dl of blood ZPP is considered as unacceptable limit of lead intoxication, more than 10 percent of workers belonged to this category in 1983, but only 0.5 of workers showed their blood ZPP level over the 150ug/dl in 1986 It was observed that no workers whose work duration were less than one year showed their blood ZPP level over 100ug/dl, but there were high percentages of lead workers with high blood ZPP (over 150 ug/dl) who were working in uncontrolled had working condition and whose work duration were less than one year.

• Restorative Dentistry and Endodontics
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• v.40 no.3
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• pp.209-215
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• 2015

Objectives: The aim of this study was to evaluate the fluoride release of conventional glass ionomer cements (GICs) and resin-modified GICs. Materials and Methods: The cements were grouped as follows: G1 (Vidrion R, SS White), G2 (Vitro Fil, DFL), G3 (Vitro Molar, DFL), G4 (Bioglass R, Biodinamica), and G5 (Ketac Fil, 3M ESPE), as conventional GICs, and G6 (Vitremer, 3M ESPE), G7 (Vitro Fil LC, DFL), and G8 (Resiglass, Biodinamica) as resin-modified GICs. Six specimens (8.60 mm in diameter; 1.65 mm in thickness) of each material were prepared using a stainless steel mold. The specimens were immersed in a demineralizing solution (pH 4.3) for 6 hr and a remineralizing solution (pH 7.0) for 18 hr a day. The fluoride ions were measured for 15 days. Analysis of variance (ANOVA) and Tukey's test with 5% significance were applied. Results: The highest amounts of fluoride release were found during the first 24 hr for all cements, decreasing abruptly on day 2, and reaching gradually decreasing levels on day 7. Based on these results, the decreasing scale of fluoride release was as follows: G2 > G3 > G8 = G4 = G7 > G6 = G1 > G5 (p < 0.05). Conclusions: There were wide variations among the materials in terms of the cumulative amount of fluoride ion released, and the amount of fluoride release could not be attributed to the category of cement, that is, conventional GICs or resin-modified GICs.

• Journal of Microbiology
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• v.43 no.5
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• pp.417-423
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• 2005

In this study, the nematode-trapping fungus, Monacrosporium sphaeroides, was transformed with a plasmid harboring the hygromycin B phosphotransferase gene, via restriction enzyme-mediated integration (REMI). Frequencies of up to 94 transformants ${\mu}g^{-1}$ per linearized plasmid DNA were obtained by optimizing the PEG concentration, as well as the category and quantity of the added restriction enzyme. $90\%$ of the transformants were determined to be stable for drug resistance when 20 randomly selected transformants were tested. Southern analyses revealed that the transforming DNA was integrated into the M. sphaeroides genome either with or without rearrangement. Five mitotic stable mutant strains were obtained using this approach, all of which had been altered with regard to sporulation capacity and pathogenicity toward nematodes. Southern blot analyses of the five mutants revealed that foreign plasmid DNA had integrated into the genome. Three of the mutants, Tms2316, Tms3583 and Tms1536, exhibited integration at a single location, whereas the remaining two, Tms32 and Tms1913, manifested integration at double or multiple locations. Our results suggest that the transformation of M. sphaeroides via REMI will facilitate insertional mutagenesis, the functional analysis of a variety of genes, and the tagging or cloning of genes of interest.