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Design of Low Power 12Bit 80MHz CMOS D/A Converter using Pseudo-Segmentation Method (슈도-세그멘테이션 기법을 이용한 저 전력 12비트 80MHz CMOS D/A 변환기 설계)

  • Joo, Chan-Yang;Kim, Soo-Jae;Lee, Sang-Min;Kang, Jin-Ku;Yoon, Kwang-Sub
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.45 no.4
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    • pp.13-20
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    • 2008
  • This paper describes the design of low power 12bit Digital-to-Analog Converter(D/A Converter) using Pseudo-Segmentation method which shows the conversion rate of 80MHz and the power supply of 1.8V with 0.18um CMOS n-well 1-poly 6-metal process for advanced wireless communication system. Pseudo-segmentation method used in binary decoder consists of simple parallel buffer is employed for low power because of simpler configuration than that of thermometer decoder. Also, using deglitch circuit and swing reduced drivel reduces a switching noise. The measurement results of the proposed low power 12bit 80MHz CMOS D/A Converter shows SFDR is 66.01dBc at sampling frequency 80MHz, input frequency 1MHz and ENOB is 10.67bit. Integral nonlinearity(INL) / Differential nonlinearity(DNL) have been measured ${\pm}1.6LSB/{\pm}1.2LSB$. Glich energy is measured $49pV{\cdot}s$. Power dissipation is 46.8mW at 80MHz(Maximum sampling frequency) at a 1.8V power supply.

Predictive Value of IHC4 Score for Pathological Response to Neoadjuvant Chemotherapy in Hormone Receptor-Positive Breast Cancer

  • Elsamany, Shereef;Elmorsy, Soha;Alzahrani, Abdullah;Rasmy, Ayman;Abozeed, Waleed N;Mohammed, Amrallah A;Sherisher, Mohamed A;Abbas, Mohammed M;Mashhour, Miral
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.17
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    • pp.7975-7979
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    • 2015
  • Purpose: This study aimed to explore the value of IHC4 in predicting pathological response after neoadjuvant chemotherapy in patients with hormonal receptor (HR)-positive breast cancer (BC). Materials and Methods: In this retrospective exploratory study, data for 68 HR-positive BC patients who received neoadjuvant chemotherapy were recorded. IHC4 scores were calculated based on estrogen receptors/progesterone receptors, Ki-67 and HER2 status. Logistic and ordinal regression analyses in addition to likelihood ratio test were used to explore associations of IHC4 scores and other clinico-pathological parameters with pathological complete response (pCR) and pathological stage. Results: Taking the 25th percentile as the cut-off, a lower IHC4 score was associated with an increased probability of pCR (low; 52.9% vs. High; 21.6%, OR=4.1, 95% CI=1.28-13.16, p=0.018) and a lower pathological stage (OR=3.9, 95% CI=1.34-11.33, p=0.012). When the IHC4 score was treated as a continuous variable, a lower score was again associated with an increased probability of pCR (OR=1.010, 95% CI=1.001-1.018, p=0.025) and lower pathological stage (OR=1.009, 95% CI=1.002-1.017, P=0.008). Lower clinical stage was associated with a better pCR rate that was of borderline significance (P=0.056). When clinical stage and IHC4 score were incorporated together in a logistic model, the likelihood ratio test gave a P-value of 0.004 after removal of the IHC4 score and 0.011 after removal of the stage, indicating a more significant predictive value of the IHC4 score for pCR. Conclusions: This study suggests that the IHC4 score can predict pathological response to neoadjuvant chemotherapy in HR-positive BC patients. This finding now needs to be validated in a larger cohort of patients.

Basic Oxygen Furnace Slag as a Liming Agent for Paddy and Upland Field Soils (전로슬래그 시용의 토양개량 및 작물의 수량증대 효과)

  • 이충일
    • Resources Recycling
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    • v.7 no.1
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    • pp.50-56
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    • 1998
  • Basic oxygen furnace @OF) slag. a by-pradud of thc iron and steelmaking industry produced in largc quantities in Korea, poszs a subslantial disposal challenge. The BOF slag used in this study was if3 CaCO, in total n e u ~ ~ pnowger and application of 7-8 Mgha' was needed to bring soil pH to 6.5 horn pH 5.0-5.5 m silly clay or clay loam sod wnlained about 10% orgaoic matter. A field assay was conducted to shldg whether BOP slag could bc used as a dolomitic k i n g agent for agricullural soils. Four slag rates (0, 4, 8, 12 Mgha-')were investigated for their effcfect on soil pmperti~, mineral concentralions in leaf tissues of rice and soybean, and yield of the crops. Slag application at 8 Mgha-' rate in paddy field increased pH, Ca Mg, P, Si and Fe wntenl in sail and rice yield by 4.3-14.25 depending an the soil type. h upland field the 8 Mghaf ratc increa3ed pH, Ca and Fe wntent m soil and soybean yield by 36.6%. Thus, BOF slag appears to be a useful liming mate&\ulcornerl for corrzch~gs oil acidity on both paddy and upland ficld soils and for innwing Ca, Mg, P, Si, and Fe wncenhation in plants.

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Predictors Affecting Breast Self-Examination Practice among Turkish Women

  • Doganer, Yusuf C.;Aydogan, Umit;Kilbas, Zafer;Rohrer, James E.;Sari, Oktay;Usterme, Necibe;Yuksel, Servet;Akbulut, Halil;Balkan, Salih M.;Saglam, Kenan;Tufan, Turgut
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.20
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    • pp.9021-9025
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    • 2014
  • Background: Breast cancer (BC) is the most common cancer among females in Turkey. Predictors affecting the breast self-examination (BSE) performance vary in developing countries. Objective: To determine the frequency of BSE performance and predictors of self-reported BSEs among women in the capital city of Turkey. Materials and Methods: This cross-sectional study was conducted on 376 Turkish women using a self-administered questionnaire covering socio-demographic variables and BSE-related features. Results: Of the participants, 78.7% (N=296) reported practicing BSE, whereas 9.5% (N=28) were implementing BSE regularly on a monthly basis, and only 5.7% (N=17) were performing BSE regularly within a week after each menstrual cycle. Multivariate logistic regression modeling revealed that BSE performance was more likely in younger age groups [20-39 years] (p=0.018, OR=3.215) and [40-49 years] (p=0.009, OR=3.162), women having a family history of breast disease (p=0.038, OR=2.028), and housewives (p=0.013, OR=0.353). Conclusions: Although it appears that the rates of BSE performers are high, the number of women conducting appropriate BSE on a regular time interval basis is lower than expected. Younger age groups, family history of breast diseases and not being employed were identified as significant predictors of practicing BSE appropriately. Older age and employment were risk factors for not performing BSE in this sample.

2.6 GHz GaN-HEMT Power Amplifier MMIC for LTE Small-Cell Applications

  • Lim, Wonseob;Lee, Hwiseob;Kang, Hyunuk;Lee, Wooseok;Lee, Kang-Yoon;Hwang, Keum Cheol;Yang, Youngoo;Park, Cheon-Seok
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.16 no.3
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    • pp.339-345
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    • 2016
  • This paper presents a two-stage power amplifier MMIC using a $0.4{\mu}m$ GaN-HEMT process. The two-stage structure provides high gain and compact circuit size using an integrated inter-stage matching network. The size and loss of the inter-stage matching network can be reduced by including bond wires as part of the matching network. The two-stage power amplifier MMIC was fabricated with a chip size of $2.0{\times}1.9mm^2$ and was mounted on a $4{\times}4$ QFN carrier for evaluation. Using a downlink LTE signal with a PAPR of 6.5 dB and a channel bandwidth of 10 MHz for the 2.6 GHz band, the power amplifier MMIC exhibited a gain of 30 dB, a drain efficiency of 32%, and an ACLR of -31.4 dBc at an average output power of 36 dBm. Using two power amplifier MMICs for the carrier and peaking amplifiers, a Doherty power amplifier was designed and implemented. At a 6 dB back-off output power level of 39 dBm, a gain of 24.7 dB and a drain efficiency of 43.5% were achieved.

An 1.2V 8-bit 800MSPS CMOS A/D Converter with an Odd Number of Folding Block (홀수개의 폴딩 블록으로 구현된 1.2V 8-bit 800MSPS CMOS A/D 변환기)

  • Lee, Dong-Heon;Moon, Jun-Ho;Song, Min-Kyu
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.47 no.7
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    • pp.61-69
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    • 2010
  • In this paper, an 1.2V 8b 800MSPS A/D Converter(ADC) with an odd number of folding block to overcome the asymmetrical boundary-condition error is described. The architecture of the proposed ADC is based on a cascaded folding architecture using resistive interpolation technique for low power consumption and high input frequency. The ADC employs a novel odd folding block to improve the distortion of signal linearity and to reduce the offset errors. In the digital block, furthermore, we use a ROM encoder to convert a none-$2^n$-period code into the binary code. The chip has been fabricated with an $0.13{\mu}m$ 1P6M CMOS technology. The effective chip area is $870{\mu}m\times980{\mu}m$. SNDR is 44.84dB (ENOB 7.15bit) and SFDR is 52.17dBc, when the input frequency is 10MHz at sampling frequency of 800MHz.

Construction of a Genetic Linkage Map in Radish(Raphanus sativus L.) Using RAPD Markers (RAPD 마커를 이용한 무의 유전자지도 작성)

  • Ahn, Choon-Hee;Choi, Su-Ryun;Lim, Yong-Pyo;Chung, Hae-Joon;Yae, Byeong-Woo;Yoon, Wha-Mo
    • Journal of Plant Biotechnology
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    • v.29 no.3
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    • pp.151-159
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    • 2002
  • Genetic map and molecular marker have a great importance in improving and facilitating crop breeding program as well as in genome analysis and map-based cloning of genes representing desirable characters. This study aimed at developing RAPD markers and constructing a genetic linkage map using 82 BC$_1$F$_1$individuals originated from the cross between '835' and B$_2$in radish (Raphanus sativus L.). One of the parents for genetic linkage map construction, '835'(P$_1$) of egg type is susceptible to Fusarium wilt and have medium resistance to virus infection and the other parent, B$_2$(P$_2$) of round type, is susceptible to Fusarium wilt and virus, Screening of 394 RAPD primers in BC$_1$F$_1$) population resulted in selecting 128 polymorphic markers which displayed 1:1 segregation pattern. Two markers failed to display 1:1 segregation and showed the segregation ratio skewed to maternal genotype. Selected markers were categorized into 14 linkage group based on LOD score represented by MAPMAKER/EXP program. Five groups composed of single marker among them were excluded from the linkage map, and consequently, the remaining groups are well matched with the number of radish chromosome (n=9). The linkage map constructed with 128 markers covers 1,688.3 cM and the average distance between markers was 13.8 cM. For developing STS marker, we determined the partial nucleotide sequence of OPE10 marker at both ends and designed a oligonucleotide primer pair based on this sequence. STS PCR using the primer pair displayed a single, clear band of which segregation is perfectly matched with that of OPE10 marker. This implies that RAPD markers could readily convert into clear and reliable STS markers.

A Study on the Effect of an HRT of Anoxic Reactors on Organic Matter and Nitrogen Removal in A2/O Processes with Bio Contact Media in Aerobic Tank (호기조에 고정상 담체를 충진한 A2/O공정에서 무산소조 체류시간 변화가 유기물질 및 질소 제거에 미치는 영향)

  • Whang, Gye-Dae;Han, Bong-Seok
    • Journal of Korean Society on Water Environment
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    • v.23 no.4
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    • pp.451-457
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    • 2007
  • Four parallel $A^2/O$ systems maintaining an MLSS of 3,000 mg/L were operated to investigate the effects of varying an HRT of anoxic reactors and packing Bio contact media (BCM, fixed beds) in aerobic reactors on organic matter removal and nitrification/denitrification efficiencies. All systems were operated under conditions that the external recycle ratio was kept 0.5 Q while the internal recycle ratio was changed 1.0 Q to 1.5 Q with that $NH_4-N$ concentration of feed was increased to 40 mg/L by adding $NH_4Cl$. In terms of TSS and TCODcr removal efficiency, both systems with BCM and a system without BCM, respectively, had a similar level of the removal efficiency under varied HRTs of anoxic reactors (0.6 hr, 1.3 hr, 2 hr, 2 hr; control, without BC M) showing that varying an HRT of anoxic reactors did not affect the removal efficiency. While SCODcr removal efficiency of systems with BCM was improved approximately 4~5% at the same HRT of anoxic reactor, the removal efficiency of system with BCM was slightly decreased by reducing an HRT of anoxic reactor. The nitrification efficiency for both systems with BCM and a system without BCM was above 94% showing that packing BCM in aerobic reactors and varying an HRT of anoxic reactors did not affect the efficiency significantly despite of increasing $NH_4-N$ concentration of feed. The denitrification efficiency increased from 81.4% to 85.4% at system with BCM while the efficiency decreased when a shorter HRT of anoxic reactors was kept. The excellent effluent quality for $NO_3-N$ concentration was observed although the $NO_3-N$ concentration increased in anoxic reactors that $NH_4-N$ concentration of feed sufficiently converted into nitrate through nitrification. As a result, packing 20% BCM to an aerobic reactor with HRT of 1.3 hr of anoxic reactor in $A^2/O$ system can achieve a similar level of nitrogen removal efficiency in $A^2/O$ system which the aerobic reactor had no BCM and HRT of 2 hr for anoxic reactor is maintained.

Design of a Wide-Frequency-Range, Low-Power Transceiver with Automatic Impedance-Matching Calibration for TV-White-Space Application

  • Lee, DongSoo;Lee, Juri;Park, Hyung-Gu;Choi, JinWook;Park, SangHyeon;Kim, InSeong;Pu, YoungGun;Kim, JaeYoung;Hwang, Keum Cheol;Yang, Youngoo;Seo, Munkyo;Lee, Kang-Yoon
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.16 no.1
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    • pp.126-142
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    • 2016
  • This paper presents a wide-frequency-range, low-power transceiver with an automatic impedance-matching calibration for TV-white-space (TVWS) application. The wide-range automatic impedance matching calibration (AIMC) is proposed for the Drive Amplifier (DA) and LNA. The optimal $S_{22}$ and $S_{11}$ matching capacitances are selected in the DA and LNA, respectively. Also, the Single Pole Double Throw (SPDT) switch is integrated to share the antenna and matching network between the transmitter and receiver, thereby minimizing the systemic cost. An N-path filter is proposed to reject the large interferers in the TVWS frequency band. The current-driven mixer with a 25% duty LO generator is designed to achieve the high-gain and low-noise figures; also, the frequency synthesizer is designed to generate the wide-range LO signals, and it is used to implement the FSK modulation with a programmable loop bandwidth for multi-rate communication. The TVWS transceiver is implemented in $0.13{\mu}m$, 1-poly, 6-metal CMOS technology. The die area of the transceiver is $4mm{\times}3mm$. The power consumption levels of the transmitter and receiver are 64.35 mW and 39.8 mW, respectively, when the output-power level of the transmitter is +10 dBm at a supply voltage of 3.3 V. The phase noise of the PLL output at Band 2 is -128.3 dBc/Hz with a 1 MHz offset.

Effects of Ballet Program Training of Royal Academy of Dance on Body Composition, Physical Fitness and Bone Mineral Density in College Women (로얄 아카데미 발레댄스 프로그램 수행이 여자 대학생의 신체조성, 체력 및 골밀도에 미치는 영향)

  • Kim, Jong-Won;Lee, Mi-Ran;Lee, Kyung-Hee;Kim, Hyung-Jun;Choi, Mun-Ki;Kim, Do-Yeon;Kim, Tae-Un
    • Journal of Life Science
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    • v.19 no.8
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    • pp.1093-1103
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    • 2009
  • The purpose of this study was to analyze the effects of ballet program training at the Royal Academy of dance (RAD) on body composition (BC), physical fitness (PF) and bone mineral density (BMD) in college women. The subjects for this study were 14 females aged 19 to 22, who were divided into the Experimental group (n=7, EG) and the Control group (n=7, CG). The RAD ballet program training was done by 7 subjects (EG), 60 minutes per day, three times a week for 12 weeks. The TBF and %fat significantly decreased and LBM increased in the Experimental group, but all the variables of Body composition in the Control group did not significantly changed. The AMS, Sit ups, STF, SLJ CFB and 1,200 m R & W in the EG significantly increased, but 1,200 m R & W in the CG decreased. The lumbar vertebra (LV), femoral neck (FN), greater trochanter (GT) and ward's triangle (WT) did not significantly change in the EG, but LV, GT and WT in the CG decreased. There was no significant difference in osteopenia for EG, but there were increases in GT and WT for the CG. There was significant correlation between BMDs and body weight, TBF, LBM, %fat, BMI, AMS. There was significant correlation between LV and FN and LV and whole body. In conclusion, regular and continuous RAD training was effective in improving the body composition, physical fitness and bone mineral density. Consequently, RAD training will be effective for preventing osteopenia and osteoporosis, and for improving the health-related fitness for college and middle-aged women.