• Journal of Korean Neurosurgical Society
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• 제42권6호
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• pp.478-480
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• 2007

Unruptured non-traumatic dissecting aneurysm in the M4 segment of the middle cerebral artery (MCA) accompanied by complete occlusion of the ipsilateral internal cerebral artery (ICA) has never been reported. A 41-year-old man presented with an infarction manifesting as left-sided weakness and dysarthria. Magnetic resonance angiography revealed a subacute stage infarction in the right MCA territory and complete occlusion of the right ICA. Angiography demonstrated aneurysmal dilatation of the M4 segment of the right MCA. Surgery was performed to prevent hemorrhage from the aneurysm. The aneurysm was proximally clipped guided by Navigation-CT angiography and flow to the distal MCA was restored by superficial temporal artery-middle cerebral artery (STA-MCA) anastornosis. We report this rare case with literature review.

• Reproductive and Developmental Biology
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• 제34권2호
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• pp.103-109
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• 2010

Functional regulation of a specific tissue or organ is controlled by a number of ways, including local cell-cell interaction. Of several forms of cell-cell junctional complexes, gap junctions are caught a great attention due to a formation of direct linkage between neighboring cells. Gap junctions are consisted of connexin (Cx) isoforms. In the present study, we evaluated expressional profiling of Cx isoforms in the rat initial segment (IS) of the male reproductive tract at different postnatal ages. The presence and expression of 13 Cx isoform mRNAs were determined by semi-quantitative real-time PCR analyses. A total of 8 Cx isoform mRNAs were detected in the IS of the male rats during postnatal development. The highest level of Cx30.3 mRNA was found at 5 months of age, while abundance of Cx31 mRNA was the highest at 1 year of age. Expression of Cx31.1 gene was relatively consistent during the postnatal development. Fluctuation of Cx32 and 37 gene expression was observed during the postnatal period. Significant elevation of Cx40 mRNA abundance was detected at 25 days of age and older ages. Expression patterns of Cx43 and 45 genes were similar with the highest level at 2 weeks of age, followed by gradual decreases at older ages. These results indicate differential regulation on expression of Cx isoforms in the rat IS during postnatal development. A complicated regulation of gene expression of Cx isoforms in the IS at different postnatal ages is suggested.

• 한국운동역학회지
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• 제17권1호
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• pp.29-39
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• 2007

This study were obtained elapsed time phase-by-phases, displacement, user angle, velocity and angular velocity to analyse kinematically contributing factors at impact of forehand drive motion, on targeting three male players. The results of the study were presented as follows; In the forehand drive swing, the elapsed time by phases was a total of .52 seconds: .30 seconds from backswing to impact and .22 seconds from impact to follow-through, Considering the mean change in locations of COM of each(part$\rightarrow$body segment) at impact, racket head, left shoulder, right wrist and left hip, the left-right directions(X-axis) were showm to be each $.61{\pm}.03$, $1.19{\pm}.08$, $.66{\pm}.03$, $.94{\pm}.06$, and $.45{\pm}.03m$. The displacement differences of COM of each body segment were shown to be -.57, -.05, -.33, and .16m. For the vertical direction(Z-axis), the center of mass was lowest at impact and highest at E3. For the displacement of the right wrist on the left hip, the right wrist moved to .82m to the lower direction without change in the locations of the hip from E1 from E2. When the left hip moved .02m from E2 to E3, the right wrist moved .7m in the upper direction. In respect to the velocity of each body segment, the hip and the shoulder joint accelerated and then the wrist followed. Then the right wrists of all the subjects and their racket heads showed maximum speed, and an effective swing was observed. At the angle of each part, the angle of the right wrist was the smallest at the backswing and the largest at the moment of the impact. Then it increased gradually in the follow-through section. In respect of angular velocity for subject A, the hip moved and the largest change occurred. Immediately before the impact, the subject made a swing using his right wrist, his hip, and the shoulder joint, showing the maximum value, which was judged to be effective.

• Macromolecular Research
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• 제10권4호
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• pp.230-235
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• 2002

Alternating polyols of oxymethylene and oxyalkylene were synthesized and used as precursors for thermoplastic poly(ether-ester) elastomers (TPEs). The polyols were synthesized by reacting diols having different methylene units with dichloromethane in the presence of a phase transfer catalyst. The number of methylene units in the alkylene oxides was varied from 3 to 6. TPEs were prepared using the polyols as soft segments and poly(butylene terephthalate) units as hard segments. The polyols and TPEs synthesized were characterized using FTIR, NMR, GPC, DSC, and polarized optical microscopy. The polyols showed a profound odd-even effect on the melting (T$_{m}$) and glass transition temperatures (T$_{g}$). Polyols with odd numbers of methylene groups in the alkylene units have higher transition temperatures than polyols with odd number of methylene groups. The tendency is still kept in TPEs, even though the T$_{g}$ of soft segment in TPEs are slightly higher than those of corresponding neat polyols. The T$_{m}$ and T$_{g}$ of soft segments are almost constant in the range of 20 to 60 wt % contents of soft segments. On the other hand, the normalized heat of fusion of hard segment decreased with increasing the content of loft segment.ent.t.ent.

• Archives of Pharmacal Research
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• 제26권2호
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• pp.173-181
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• 2003

A polymeric micelle drug delivery system was developed to enhance the solubility of poorly-water soluble drug, biphenyl dimethyl dicarboxylate, DDB. The block copolymers consisting of poly(D,L-lactide) (PLA) as the hydrophobic segment and methoxy poly(ethylene glycol) (mPEG) as the hydrophilic segment were synthesized and characterized by NMR, DSC and MALDI-TOF mass spectroscopy. The size of the polymeric micelles measured by dynamic light scattering showed a narrow monodisperse size distribution with the average diameter less than 50 nm. The MW of mPEG-PLA, 3000 (MW of mPEG, 2 K; MW of PLA, 1K), and the presence of hydrophilic and hydrophobic segments on the polymeric micelles were confirmed by MALDI-TOF mass spectroscopy and NMR, respectively. Polymeric micelle solutions of DDB were prepared by three different methods, i.e. the matrix method, emulsion method and dialysis method. In the matrix method, DDB solubility was reached to 13.29 mg/mL. The mPEG-PLA 2K-1K micelle system was compared with the poloxamer 407 micelle system for their critical micelle concentration, micelle size, solubilizing capacity, stability in dilution and physical state. DDB loaded-polymeric micelles prepared by the matrix method showed a significantly increased aqueous solubility (＞5000 fold over intrinsic solubility) and were found to be superior to the poloxamer 407 micelles as a drug carrier.

• 한국운동역학회지
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• 제20권4호
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• pp.447-455
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• 2010

The objective of this study was to analyze the difference in kinematic variables for successful and unsuccessful golf putting strokes. The study population included 8 male secondary school golf players who had played golf for over 3 years and whose handicap was 4 or lower. A hole was made on a 5-m-long artificial flat mat for practice, and an environment similar to that of a real green was created. The participants' motions were analyzed through 3D image analysis, and the difference in kinematic variables for successful and unsuccessful putting strokes in the same direction was determined. Data analysis revealed the following findings: The time spent for a segment of putting was the greatest for the backswing segment for both successful and unsuccessful strokes. During address and impact, the both changed to a larger extent. For successful putting strokes, the change in the elbow angle during the downswing was greater for the right elbow than for the left elbow. For both successful and unsuccessful putting strokes, the left shoulder angle increased during the segment from address to the turning point and decreased during the segment from the turning point to impact. In contrast, the right shoulder angle significantly differed between successful and unsuccessful putting strokes only during address. During successful and unsuccessful motions, the swing was executed with the moving displacement of the X-axis of the club head maintained almost constant along a straight light without back and forth movement. In the backswing segment, moving displacement of the Y- and Z-axes was greater in successful strokes than in unsuccessful strokes; however, this difference was very small for the Y-axis. The velocity of the club head for successful and unsuccessful motions significantly differed during address and at the turning point. The highest velocity of the ball was greater for successful than for unsuccessful putting strokes.

• Journal of Microbiology and Biotechnology
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• 제10권1호
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• pp.48-50
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• 2000

The energetics at the succinate:quinone oxidoreductase segment of V. alginolyticus was studied using a fluorescence quenching technique with inside-out membrane vesicles. A transient generation of the membrane potential (inside-positive) and ${\Delta}pH$ (inside-acidic) occurred in the presence of KCN and succinate when ubiquinone-1 (Q1) was added. The membrane potential (\Delta\psi$) generated by the succinate; quinone oxidoreductase segment was completely collapsed by the protonophore carbonylcyanide m-chlorophenylhydrazone (CCCP) and the membrane permeable anion $SCN^{-}$, whereas the ${\Delta}pH$ was completely collapsed by CCCP and $(NH_4)_2SO_4$. From these results, it was concluded that the succinate: quinone oxidoreductase segment as well as quinol oxidase [1] in the respiratory chain of V. alginolyticus generated $H^{+}$ electrochemical potential.

• Fibers and Polymers
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• 제3권4호
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• pp.153-158
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• 2002

A series of waterborne polyurethanes (WBPU) were prepared from 4,4-dicyclohexylmethane diisocyanate ($H_{12}$MDI),2,2-bis(hydroxylmethyl) propionic acid (DMPA), othylenediarnine (EDA), triethylamine (TEA), and triblock glycol [TBG, ($\varepsilon$-caprolactone)$_{4.5}$-poly(tetramethylene ether) glycol (MW= 2000)-($\varepsilon$-caprolactone)$_{4.5}$: $(CL)_{4.5}$-PTMG-$(CL)_{4.5}$, MW=3000] as a soft segment. Two melting peaks of TBG at about 14$^{\circ}C$ and 38$^{\circ}C$ were observed indicating the presence of two different crystalline domains composed of CL and PTMG dominant component. The effect of soft segment content (60-75 wt%) on the colloidal properties of dispersion, and thermal and mechanical properties of WBPU films, the water vapor permeability (WVP) and water resistance (WR) of WBPU-coated Nylon fabrics, and the adhesive strength of WBPU- coated layer and Nylon fabrics was investigated. As soft segment contents increased, the water vapor permeability of WBPU- coated Nylon fabrics increased from 3615 to 4502 g/$m^2$day, however, the water resistances decreased from 1300 to 500 mm$H_2$O.O.

• 한국항행학회논문지
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• 제19권5호
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• pp.403-410
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• 2015

ADS-B는 레이더에 비하여 높은 정확도와 빠른 갱신 주기를 제공하여, 레이더를 대체하거나 보완할 수 있는 기술이다. 최근 증가하는 항공교통량과 이에 따른 정확한 감시의 요구에 의하여 ADS-B가 실제 항공기 운영에 적용되고 있다. 본 논문은 항공기가 운항 중 상시 송신하는 ADS-B 신호를 활용한 공한 인근 지역에서 정밀 감시가 가능한지 확인하기 위한 자료 수집과 일부 데이터에 대한 분석을 수행하였다. 이를 위하여 정밀계기 착륙 접근하는 항공기의 ADS-B 항적을 수집하고, 최종접근 구간에서 항적의 분포 특성에 관한 분석을 수행하였다. 분석결과 ADS-B 항적은 활주로 중심선 연장선에 대하여 평균 이격 거리 -0.04 m, 표준편차 6.71 m이고, 또한 비교적 정확한 감시정보의 제공이 가능함을 확인하였다.

• 한국터널지하공간학회 논문집
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• 제13권3호
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• pp.233-242
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• 2011

본 연구에서는 쉴드터널에 사용되는 세그먼트의 성능향상과 경제성향상을 위하여 고로슬래그 미분말을 혼합한 고강도 콘크리트에 대한 기초 연구를 실시하였다. 특히, 설계강도가 60 MPa 세그먼트용 콘크리트에 대해서 고로슬래그 미분말의 최적 치환율과 최적의 증기양생 조건을 도출하고자 하였다. 이상의 결과로부터, 고로슬래그 치환율 50%와 단위수량 125 kg/$m^3$ 일 경우가 성능과 경제적인 측면에서 가장 적합한 배합조건으로 나타났다. 또한 표준양생 조건과 비교할 때 증가양생에 의하여 약 110~442%의 강도증진 효과를 기대할 수 있는 것으로 확인되었다.