• Title/Summary/Keyword: M/G/c

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Estimation of Carbon Storages and Fluxes by Ecosystem Type in Korea (국내 생태계 유형별 탄소 저장 및 거동 산정 연구 현황 분석)

  • Inyoung Jang;Heon Mo Jeong;Sang-Hak Han;Na-Hyun Ahn;Dukyeop Kim;Sung-Ryong Kang
    • Journal of Wetlands Research
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    • v.25 no.4
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    • pp.417-425
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    • 2023
  • As climate change gets severe, the ecosystem acts as an important carbon sink, therefore efforts are being made to utilize these functions to mitigate climate change. In this study, we inventoried and analyzed the previous studies related to carbon storage and flux by ecosystem type (forest, cropland, wetland, grassland, and settlement) and carbon pool (aboveground and belowground biomass, dead wood, Litter, soil organic carbon, and ecosystem) in Korean ecosystems. We also collected the results of previous studies and calculated the average value of carbon storage and flux for each ecosystem type and carbon pool. As a result, we found that most (66%) of Korea's carbon storage and fluxes studies were conducted in forests. Based on the results of forest studies, we estimated the storage by carbon stock. We found that much carbon is stored in vegetation (aboveground: 4,018.32 gC m-2 and belowground biomass: 4,095.63 gC m-2) and soil (4,159.43 gC m-2). In particular, a large amount of carbon is stored in the forest understory. For other ecosystem types, it was impossible to determine each carbon pool's storage and flux due to data limitations. However, in the case of soil organic carbon storage, the data for forests and grasslands were comparable, showing that both ecosystems store relatively similar amounts of carbon (4,159.43 gC m-2, 4,023.23 gC m-2, respectively). This study confirms the need to study carbon in rather diverse ecosystem types.

Differential Coupling of G$\alpha$q Family of G-protein to Muscarinic $M_1$ Receptor and Neurokinin-2-Receptor

  • Lee, Chang-Ho;Shin, In-Chul;Kang, Ju-Seop;Koh, Hyun-Chul;Ha, Ji-Hee;Min, Chul-Ki
    • Archives of Pharmacal Research
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    • v.21 no.4
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    • pp.423-428
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    • 1998
  • The ligand binding signals to a wide variety of seven transmembrane cell surface receptors are transduced into intracellular signals through heterotrimeric G-proteins. Recently, there have been reports which show diverse coupling patterns of ligand-activated receptors to the members of Gq family $\alpha$ subunits. In order to shed some light on these complex signal processing networks, interactions between G$\alpha$q family of G protein and neurokinin-2 receptor as well as muscarinic M$_{1}$ receptor, which are considered to be new thearpeutic targets in asthma, were studied. Using washed membranes from Cos-7 cells co-transfected with different G.alpha.q and receptor cDNAs, the receptors were stimulated with various concentrations of carbachol and neurokinin A and the agonist-dependent release of [$^3H$]inositol phosphates through phospholipase C beta-1 activation was measured. Differential coupling of Gaq family of G-protein to muscarinic M$_{1}$ receptor and neurokinin-2 receptor was observed. The neurokinin-2 receptor shows a ligand-mediated response in membranes co-transfected with G$\alpha$q, G$\alpha$11 and G$\alpha$14 but not G$\alpha$16 and the ability of the muscarinic $M_1$ receptor to activate phospholipase C through G$\alpha$/11 but not G$\alpha$14 and G$\alpha$16 was demonstrated. Clearly G$\alpha$/11 can couple $\M_1$ and neurokinin-2 receptor to activate phospholipase C. But, there are differences in the relative coupling of the G$\alpha$14 and G$\alpha$16 subunits to these receptors.

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Effect of Temperature on Mitotic Cycle of Rice Root Meristem Cells (벼 뿌리세포의 유사분열주기에 대한 배양온도의 영향)

  • 김재철;이승준;권성환;곽성희
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.35 no.1
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    • pp.65-72
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    • 1990
  • The mitotic cycle duration and component plase periods of rice (Oryza sativa L. 'Sumjinbyeo and Seokwangbyeo') root merisem cells at 15, 20, and 30$^{\circ}C$ were determined the use of tritiated thymidine, In this work, the time interval between the maxima of sequential mitotic appearances of marked cells was used to estimate the mitotic cycle duration (MCD) of rice, The MCD of rice of the cultivar 'Sumjinbyeo' and 'Seokwangbyeo' at 20. and 30$^{\circ}C$ was 12. and 20hr, respectively. But the MCD of 'Sumjinbyeo' and 'Seokwangbyeo' was 18 and 20hr, at 15$^{\circ}C$. respectively. The MCD decreased with increasing temperature, The duration of component phase of rice cultivar 'Seokwangbyeo' were essentially the same ratio at 20$^{\circ}C$ and 30$^{\circ}C$. but in 'Sumjinbyeo' cultivar the ratio of $G_1$ period was almost doubled while those of $G_2$ and M were decreased by almost two times at 20$^{\circ}C$ and 30$^{\circ}C$. Deoxyribonucleic acid (DNA). Ribonucleic acid (RNA), and protein synthesis were reduced with increasing temperature from 15$^{\circ}C$ to 30$^{\circ}C$ while the MCD was decreased, This result suggest that DNA, RNA and protein synthesis may not affect the MCD from 15$^{\circ}C$ to 30$^{\circ}C$ in rice.

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Quality Standardization and Isoflavone Glycoside Research of in Buseoktae(Yeongju bean) Cheonggukjang for Business Use from Yeongju Bean (영주 부석태 청국장시료의 이소플라본 배당체 탐색과 청국장의 품질 표준화)

  • Choi, Eun-Young;Yu, Jin-Hyeon;An, Hui-Jeong
    • Culinary science and hospitality research
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    • v.22 no.2
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    • pp.13-28
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    • 2016
  • This study performed quantitative analysis of isoflavone glycoside contents on Buseoktae, Daewon, Wooram beans and cheonggukjang made of Buseoktae beans from the LC/MS/MS. Also, the experiment carried out by means of RSM(response surface methodology), which included 10 experimental points for the two independent variables addition(40, 55, 70 g) and time(2, 3, 4 min) from the beginning point to boil of cheonggukjang. These were optimized using a Face-centered central composite design. Daidzein contents were $212.16{\mu}g/mL$ in Buseoktae, $212.21{\mu}g/mL$ in daewon, $158.54{\mu}g/mL$ in wooram beans. Genistein contents were $318.84{\mu}g/mL$ in Buseoktae, $310.50{\mu}g/mL$ in daewon, $262.71{\mu}g/mL$ in wooram beans. Total isoflavone contents were $532.50{\mu}g/mL$ in Buseoktae, $524.19{\mu}g/mL$ in Daewon, $422.71{\mu}g/mL$ in Wooram beans. Isoflavone contents of Buseoktae and Daewon were quite similar, relatively contents of Wooram beans were low. Total isoflavone contents of Buseoktae cheonggukjang (for business use) was $430.10{\mu}g/mL$ in A ($32^{\circ}C$, 96 h fermentation), $460.09{\mu}g/mL$ in B ($36{\sim}40^{\circ}C$, 30 h fermentation), $417.46{\mu}g/mL$ in C cheonggukjang($36{\sim}38^{\circ}C$, 72 h fermentation), B cheonggukjang was just a bit more than A, C cheonggukjang. The estimated response surfaces confirmed that the amount and time had significant effects on taste. The optimum condition of Buseoktae cheonggukjang taste was predicted to be 55.20 g addition at 2.92 min.

Outcomes and Use of Therapeutic Drug Monitoring in Multidrug-Resistant Tuberculosis Patients Treated in Virginia, 2009-2014

  • Heysell, Scott K.;Moore, Jane L.;Peloquin, Charles A.;Ashkin, David;Houpt, Eric R.
    • Tuberculosis and Respiratory Diseases
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    • v.78 no.2
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    • pp.78-84
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    • 2015
  • Background: Reports of therapeutic drug monitoring (TDM) for second-line medications to treat multidrug-resistant tuberculosis (MDR-TB) remain limited. Methods: A retrospective cohort from the Virginia state tuberculosis (TB) registry, 2009-2014, was analyzed for TDM usage in MDR-TB. Drug concentrations, measured at time of estimated peak ($C_{max}$), were compared to expected ranges. Results: Of 10 patients with MDR-TB, 8 (80%) had TDM for at least one drug (maximum 6 drugs). Second-line drugs tested were cycloserine in seven patients (mean $C_{2hr}$, $16.6{\pm}10.2{\mu}g/mL$; 4 [57%] below expected range); moxifloxacin in five (mean $C_{2hr}$, $3.2{\pm}1.5{\mu}g/mL$; 1 [20%] below); capreomycin in five (mean $C_{2hr}$, $21.5{\pm}14.0{\mu}g/mL$; 3 [60%] below); para-aminosalicylic acid in five (mean $C_{6hr}$, $65.0{\pm}29.1{\mu}g/mL$; all within or above); linezolid in three (mean $C_{2hr}$, $11.4{\pm}4.1{\mu}g/mL$, 1 [33%] below); amikacin in two (mean $C_{2hr}$, $35.3{\pm}3.7{\mu}g/mL$; 1 [50%] below); ethionamide in one ($C_{2hr}$, $1.49{\mu}g/mL$, within expected). Two patients died: a 38-year-old woman with human immunodeficiency virus/acquired immune deficiency syndrome and TB meningitis without TDM, and a 76-year-old man with fluoroquinolone-resistant (pre-extensively drug-resistant) pulmonary TB and low linezolid and capreomycin concentrations. Conclusion: Individual pharmacokinetic variability was common. A more standardized approach to TDM for MDR-TB may limit over-testing and maximize therapeutic gain.

Aboveground Primary Productivity of Salix nipponica and Secondary Productivity of Sesarma dehaani at Janghang Wetland in Han River Estuary (한강하구 장항습지의 선버들(Salix nipponica)의 지상부 1차생산성과 말똥게(Sesarma dehaani)의 2차생산성)

  • Han, Dong-Uk;Yoo, Jae-Won;Yoo, Young-Han;Lee, Eun-Ju;Park, Sang-Kyu
    • Korean Journal of Ecology and Environment
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    • v.43 no.2
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    • pp.298-306
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    • 2010
  • We estimated aboveground primary productivity of Salix nipponica based on biomass using allometry and basal area at Janghang wetland in Han River estuary. In addition, we estimated secondary production of sesarmine crab (Sesarma dehaani) living under the Salix community to interpret relationships between Salix nipponica and Sesarma dehaani. Salix nipponica showed primary productivity of 4,777 g DW $m^{-2}yr^{-1}$, which appear to be the highest primary productivity in South Korea. The estimated amount of autochthonous organic matter from S. nipponica and allochthonous organic matter from the Han River into sediment was 359 g C $m^{-2}yr^{-1}$ and 347 g C $m^{-2}yr^{-1}$, respectively. The secondary productivity of Sesarma dehaani was 100.2 g FW $m^{-2}yr^{-1}$, which was 2.1% of the primary productivity of S. nipponica. The biomass of Sesarma dehanni was average 140 g FW $m^{-2}$, which consumed their prey of approximately 2,140 g FW $yr^{-1}$, which is equivalent to approximately 208 g C $m^{-2}yr^{-1}$.

The Study of Anti-inflammtory Mechanism with Bee Venom on Human Synoviocytes (인체(人體) 활막세포(滑膜細胞)를 대상으로 한 봉양침액(蜂藥鍼液)의 염증(炎症) 치료(治療) 기전(機轉) 연구(硏究))

  • Bae, Chul-woo;Song, Ho-sueb
    • Journal of Acupuncture Research
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    • v.21 no.3
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    • pp.121-131
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    • 2004
  • Objective : The purpose of this study was investigation how the bee venom(BV) prevents inflammation in human cell. Methods : we induced inflammation on human synoviocyte cell by lipopolysaccharide(LPS) and sodium nitroprusside(SNP), treated the bee venom and melittin on this cell, surveyed the expression of Nisotric oxide(NO), inducible nitric oxide synthase(iNOS), Cyclooxygenease-2(COX-2), cytolic phospholipase $A_2(cPLA_2)$, Prostaglandin $E_2(PGE_2)$ and nuclear factor-${\kappa}B$(NF-${\kappa}B$), and got below conclusions. Results : Compared with control 1. Expressions of LPS-induced $PGE_2$(BV 1, $5{\mu}g/m{\ell}$) and SNP-induced PGE2(BV 0.5, 1, $5{\mu}g/m{\ell}$)were decreased significantly. 2. Expressions of LPS-induced NO(BV 0.5, 1, $5{\mu}g/m{\ell}$) and SNP-induced NO(BV 1, $5{\mu}g/m{\ell}$)were decreased significantly. 3. Expressions of LPS-induced COX-2(BV 1, $5{\mu}g/m{\ell}$) and SNP-induced COX-2(BV $5{\mu}g/m{\ell}$)were decreased significantly. 4. Expressions of LPS-induced iNOS(BV 0.5, 1, $5{\mu}g/m{\ell}$) and SNP-induced iNOS(BV $5{\mu}g/m{\ell}$) were meanless by all dose. 5. Expressions of LPS-induced $cPLA_2$(BV 1, $5{\mu}g/m{\ell}$) and SNP-induced cPLA2(BV 1, $5{\mu}g/m{\ell}$)were decreased significantly. 6. Expressions of LPS-induced NF-${\kappa}B$(BV $5{\mu}g/m{\ell}$, melittin $5{\mu}g/m{\ell}$) and SNP-induced NF-${\kappa}B$(BV 0.5, 1, $5{\mu}g/m{\ell}$, melittin 5, $10{\mu}g/m{\ell}$)were decreased significantly. 7. Expressions of LPS-induced NF-${\kappa}B$ binding activity (BV $1{\mu}g/m{\ell}$, melittin $5{\mu}g/m{\ell}$, melittin $5{\mu}g/m{\ell}$+ DTT 20mM) were decreased significantly. Conclusion : The bee venom treatments on synoviocyte showed significant changes in LPS and SNP induced NO, iNOS, COX-2, cPLA2, PGE2 and NF-${\kappa}B$, these results suggest that bee venom is effective to inflammations and establish the process of bee venom therapy, so we expect active use of bee venom to control the inflammation.

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Organic Carbon Cycling in Ulleung Basin Sediments, East Sea (동해 울릉분지 퇴적물에서 유기탄소 순환)

  • Lee, Tae-Hee;Kim, Dong-Seon;Khim, Boo-Keun;Choi, Dong-Lim
    • Ocean and Polar Research
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    • v.32 no.2
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    • pp.145-156
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    • 2010
  • This study investigated organic carbon fluxes in Ulleung Basin sediments, East Sea based on a chamber experiment and geochemical analyses. At depths greater than 2,000 m, Ulleung Basin sediments have high organic carbon contents (over 2.0%). Apparent sedimentation rates (ASR) calculated from excess $^{210}Pb$ activity distribution, varied from 0.036 to $0.047\;cm\;yr^{-1}$. The mass accumulation rates (MAR) calculated from porosity, grain density (GD), and ASR, ranged from 131 to $184\;g\;m^{-2}\;yr^{-1}$. These results were in agreement with sediment trap results obtained at a water depth of 2100 m. Input fluxes of organic carbon varied from 7.89 to $11.08\;gC\;m^{-2}\;yr^{-1}$ at the basin sediments, with an average of $9.56\;gC\;m^{-2}\;yr^{-1}$. Below a sediment depth of 15cm, burial fluxes of organic carbon ranged from 2.02 to $3.10\;gC\;m^{-2}\;yr^{-1}$. Within the basin sediments, regenerated fluxes of organic carbon estimated with oxygen consumption rate, varied from 6.22 to $6.90\;gC\;m^{-2}\;yr^{-1}$. However, the regenerated fluxes of organic carbon calculated by subtracting burial flux from input flux, varied from 5.87 to $7.98\;gC\;m^{-2}\;yr^{-1}$. Respectively, the proportions of the input flux, regenerated flux, and burial flux to the primary production ($233.6\;gC\;m^{-2}\;yr^{-1}$) in the Ulleung Basin were about 4.1%, 3.0%, and 1.1%. These proportions were extraordinarily higher than the average of world open ocean. Based upon these results, the Ulleung Basin might play an integral role in the deposition and removal of organic carbon.

Effects of Avocado Yoghurt, Three Beans Cookie, and Tiger Nut Galsu Drink on Fibroblasts (Hs68) and Keratinocytes (HaCaT)

  • Park, Seung-Yong;Jung, Eun-Kyung;Joo, Nami;Shin, Hyun-Soo;Shin, Ji-Sun;Myoung, Da-Bin;Lee, Kyung-Tae
    • Journal of Dairy Science and Biotechnology
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    • v.37 no.2
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    • pp.136-153
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    • 2019
  • The present study aimed to investigate the effects of skin care foods on the synthesis of pro-collagen type I C peptide and suppression of matrix metalloproteinase (MMP)-1 secretion through an in vitro study using fibroblasts (Hs68 cells) and keratinocytes (HaCaT cells). Among the three skin care foods developed in this study, three beans cookie and avocado yoghurt influenced the production of pro-collagen type I C peptide and suppressed MMP-1 secretion; however, tiger nut Galsu drink did not exhibit these effects. All skin care foods, including three beans cookie and plain yoghurt ($50{\mu}g/mL$, p<0.001) influenced the suppression of MMP-1 in addition to other commercially available breast milk production support foods examined, such as Heath Heather ($50{\mu}g/mL$, p<0.001), Happy Mama ($50{\mu}g/mL$, p<0.01), BioLys ($50{\mu}g/mL$, p<0.001), Enfamama ($25{\mu}g/mL$, p<0.0001), and Pregnagen ($25{\mu}g/mL$, p<0.001). Avocado fruit yoghurt ($25{\mu}g/mL$, p<0.05), avocado fruit jam yoghurt ($50{\mu}g/mL$, p<0.01), Enfamama ($100{\mu}g/mL$, p<0.05), and Pregnagen ($100{\mu}g/mL$, p<0.05) influenced the production of pro-collagen type I C peptide and suppressed MMP-1 secretion. This result indicates that only avocado jam yoghurt significantly influenced both the prevention of skin keratinization and acceleration of recovery of skin fibrous structure. Therefore, avocado is a favorable ingredient for nutrition-balanced dietary foods or an essential ingredient in products for revitalization of human skin.

EXTENSIONS OF t-MODULES

  • Woo, Sung-Sik
    • Communications of the Korean Mathematical Society
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    • v.9 no.2
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    • pp.361-367
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    • 1994
  • An elliptic module is an analogue of an elliptic curve over a function field [D]. The dual of an elliptic curve E is represented by Ext(E, $G_{m}$) and the Cartier dual of an affine group scheme G is represented by Hom(G, G$G_{m}$). In the category of elliptic modules the Carlitz module C plays the role of $G_{m}$. Taguchi [T] showed that a notion of duality of a finite t-module can be represented by Hom(G, C) in a suitable category. Our computation shows that the Ext-group as it stands is rather too "big" to represent a dual of an elliptic module.(omitted)

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