• 제목/요약/키워드: Lymphatic diseases

검색결과 67건 처리시간 0.032초

흰쥐에서 녹차추출물의 트랜스 지방 소장 흡수 억제 작용 (Green Tea Extract Decreases the Lymphatic Absorption of Trans Fat in Rats)

  • 김주연;노상규
    • 한국식품영양과학회지
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    • 제41권1호
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    • pp.73-78
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    • 2012
  • 트랜스 지방 과다섭취는 심혈관계 질환의 위험인자이다. 이 연구는 녹차의 섭취가 대표적인 트랜스 지방인 elaidic acid의 소장 흡수율에 미치는 영향을 조사하기 위해서 설계하였다. 소장 지방 흡수를 in vivo 상태에서 측정하기 위해서 흰쥐의 '소장지방흡수모델(mesenteric lymph duct cannulated rat model)'을 이용하여 십이지장주입관(intraduodenal catether)과 림프채취관(lymph duct cannula)을 각각 십이지장과 소장 림프관에 설치하였다. 십이지장주입관으로 주입된 지질유화액은 $180.0{\mu}mol$ elaidic acid, $400.0{\mu}mol$ triolein, $20.7{\mu}mol$ cholesterol, $3.1{\mu}mol$ a-tocopherol, $396{\mu}mol$ sodium taurocholate 그리고 24 mL PBS 용액을 기본성분으로 했고 이 지질유화액만 공급받은 동물을 대조군(control), 녹차추출물이 추가된 지질유화액을 공급받은 동물을 녹차군으로 하였다. 지질유화액은 시간당 3 mL씩 8시간 동안 주입하였고 동시에 소장 림프관에 설치된 림프채취관으로 분비되는 림프 시료를 매시간 8시간 동안 채취하여 분석하였다. 결과적으로, 8시간 동안 소장 림프채취관으로 분비된 림프의 양은 녹차에 의해서 유의적으로 감소하였고 elaidic acid의 흡수율(분비율) 또한 녹차에 의해서 유의적으로 감소하였다. 콜레스테롤, 올레산, 인지질의 흡수율도 녹차에 의해서 유의적으로 감소하였다. 이상의 결과들은 녹차가 elaidic acid 뿐만 아니라 기타 주요 식이성 지방들의 소장흡수를 억제하는데 효과적인 수단이 될 수 있다는 것을 증명한 연구라 판단된다.

공동을 동반한 만성 진행성 폐렴양 병변 (Chronic Progressive Pneumonic Consolidation with Cavity)

  • 권선옥;김형중;안철민;김성규;이원영;김상진;이기범
    • Tuberculosis and Respiratory Diseases
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    • 제38권4호
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    • pp.401-405
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    • 1991
  • Bronchioloalveolar cell carcinoma accounts for less than 6% of all primary lung cancer but has distinct clinical and radiological features and unusual pathologic appearance. The characteristic features are its peripheral location and tendency of rapid progression to diffuse type via aeroginous and lymphatic route without surgical intervention. Among them, mucin secretory type bronchioloalveolar cell carcinoma is the rarest and most distinctive. We experienced a case of mucin secretory type bronchioloalveolar cell carcinoma in a 47 year old female with roentgenographic findings of chronic progressive pulmonary consolidation with muliple cavities.

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과팽창이 동반된 미만성 망상형 간질성 폐침윤 (Diffuse Reticular Interstitial infiltrations Accompanied by Hyperinflation)

  • 이계영;김영환;한성구;심영수;김건열;한용철
    • Tuberculosis and Respiratory Diseases
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    • 제40권1호
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    • pp.79-83
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    • 1993
  • A 38-year-old female was admitted due to progressive exertional dyspnea and intermittent blood tinged sputum. Chest PA showed diffuse reticular infiltration accompanied by hyperinflation. $PaO_2$ was normal in resting state but profoundly decreased during exercise. Spirometry showed severe obstructive pattern but DLCO was markedly decreased. Lung volumes measured by helium equilibrium method was increased. On HRCT, numerous and relatively uniform sized cysts were evenly distributed throughout the bilateral lung fields. Open lung biopsy was performed and pulmonary lymphangioleiomyomatosis(LAM) was diagnosed based on the findings of abnormal proliferation of smooth muscle cells in the walls of lymphatic vessels, bronchioles, and small pulmonary veins. Immunohistochemical staining was negative for estrogen receptor but positive for progesterone receptor. Medroxyprogesterone therapy was initiated.

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공장으로 전이된 원발성 폐암종 1예 (A Case of Lung with Jejunal Metastasis)

  • 이정연;리원연;신표진;김신태;김태헌;조미연;안해련;용석중;신계철
    • Tuberculosis and Respiratory Diseases
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    • 제52권5호
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    • pp.539-544
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    • 2002
  • Primary lung cancer can metastasize by a direct local extension, hematogenous dessemination, and lymphatic spread. However, it less commonly metastasizes via a transbronchial invasion. Approximately half of all patients with lung cancer have metastases at the initial presentation. Autopsy data showed that there are an average of 4.8 metastatic sites. The most common sites for metastases include the lymph nodes, liver, adrenal gland, bone, and brain. However clinically significant metastases isolated in the small bowel seldom occur. Here we report a case of lung cancer with a small bowel metastasis.

결절성 경화증에 동반된 폐의 임파관평활근종증 2예 (Two Cases of Pulmonary Lymphangioleiomyomatosis Associated with Tuberous Sclerosis)

  • 안정천;조원용;인광호;강경호;유세화
    • Tuberculosis and Respiratory Diseases
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    • 제39권6호
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    • pp.542-547
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    • 1992
  • 결절성경화증과 동반된 폐임파관평활근종증은 매우 드문 질환으로서 가임기의 여성에게 국한되어 발생한다. 저자들은 결절성경화증이 있던 39세의 여자 환자에게서 반복되는 자연기흉으로 폐조직 생검결과 폐임파관 평활근종증으로 확진된 예와 양측신 혈관근지반종을 동반한 결절성 경화증을 갖은 32세 여자 환자에서 호흡기 증상은 없었으나 흉부 X-선 및 고해상도 흉부 컴퓨터 단층 촬영상 폐임파관 평활근종증을 보였던 예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

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정보적군집 크기를 가진 군집화된 구간 중도절단자료 분석을 위한결합모형의 적용 (Statistical Analysis of Clustered Interval-Censored Data with Informative Cluster Size)

  • 김양진;유한나
    • Communications for Statistical Applications and Methods
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    • 제17권5호
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    • pp.689-696
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    • 2010
  • 구간중도 절단자료는 감염 자료, 종양 발생 자료등 그 발생 시간을 정확하게 관측할 수 없는 경우에 흔히 발생되는 자료로 정확한 사건 발생 시간대신에 발생 전 마지막 관측시점과 발생 후 첫 번째 관측시점으로 구성된다. 이러한 종류의 자료는 Sun (2006)에 의해 자세하게 논의되었으며 관측 개체간의 독립성 가정 하에서 여러 가지 방법들에 의해 분석되어져 왔다. 본 논문에서는 관측 개체들이 군집으로부터 발생하여 더 이상독립성 가정이 적절하지 못한 경우를 고려한다. 특히 반응변수인 사건 발생 시간이 군집의 크기와 연관되어 있을 때, 이를 고려하기 위한 결합 모형을 제시한다. 제안된 모형은 림프계 필라리아병의 실제 자료에 적용한다.

Current Treatments for Breast Cancer-Related Lymphoedema: A Systematic Review

  • Li, Lun;Yuan, Liqin;Chen, Xianyu;Wang, Quan;Tian, Jinhui;Yang, Kehu;Zhou, Enxiang
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권11호
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    • pp.4875-4883
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    • 2016
  • Background and objective: Breast cancer-related lymphoedema (BCRL) is a disabling complication with long term impact on quality on life after breast cancer treatment. Its management remains a major challenge for patients and health care professionals; the goal of this overview was to summarize effects of different treatment strategies for patients with BCRL. Methods: A thorough search was undertaken to allow a systematic review or meta-analysis of treatments for BCRL. Two investigators independently selected studies and abstracted the data. Results: Combined physical therapy (CPT) with different combinations of surgery, oral pharmaceuticals, low-level laser therapy, weight reduction, mesenchymal stem cell therapy, kinesio tex taping, and acupuncture might be effective in reducing lymphoedema, but exercise demonstrated no obvious benefit. The results of direct comparisons showed CPT might be more effective than standard physiotherapy (ST). Manual lymphatic drainage (MLD) may not offer additional benefits to ST for swelling reduction, but could facilitate compression bandaging. MLD seemed to have similar effects with self-administered simple lymphatic drainage (SLD) or using an intermittent pneumatic compression pump (IPC). IPC might also not be associated with additional effectiveness for CPT. Efficacy of stem cell therapy vs. compression sleeve or CPT, as well as the effects of daflon and coumarin could not be established. Conclusion: Although many treatments for BCRL might reduce lymphoedema volume, their effects were not well established. The quality of many of the original studies in the included reviews was not optimal, so that in future randomized control trials are a high priority.

Balantidiasis in Gastric Lymph Node of Barbary Sheep (Ammotragus lervia)

  • Park, Nam-yong;Cho, Ho-seong;A.W.M. Effendy;Park, Jong-woog;Kim, Tae-soon;Shin, Sung-shik
    • 한국수의병리학회:학술대회논문집
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    • 한국수의병리학회 2003년도 추계학술대회초록집
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    • pp.39-39
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    • 2003
  • Balantidiasis is an infectious disease worldwide which is produced by a protozoan Balantidium coli. This single-celled organism is characterized by their large size ranging from 50 $\mu\textrm{m}$ to more than 500 $\mu\textrm{m}$ [1] which indicated by the presence of cilia on its cell surface. The parasite occurs in the lumen of cecum and colon of swine, humans and nonhuman primates as commensal, but can turn opportunist and invade injury tissues by other diseases [2]. It is difficult to diagnose the disease clinically since they are asymptomatic [3]; and can be complicated with other disease or parasitism. Here we report the incidental findings of Balantidiasis in the lymphatic ducts of gastric lymph node of Barbary sheep (Ammotragus lervia). (omitted)

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Postoperative Chylothorax: the Use of Dynamic Magnetic Resonance Lymphangiography and Thoracic Duct Embolization

  • Lee, Chae Woon;Koo, Hyun Jung;Shin, Ji Hoon;Kim, Mi young;Yang, Dong Hyun
    • Investigative Magnetic Resonance Imaging
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    • 제22권3호
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    • pp.182-186
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    • 2018
  • Dynamic enhanced magnetic resonance lymphangiography can be used to provide anatomic and dynamic information for various lymphatic diseases, including thoracic duct injury, and can also help to guide the thoracic duct embolization procedure. We present a case of postoperative chylothorax demonstrated by dynamic enhanced MR lymphangiography. In this case, the chyle leakage site and location of cisterna chyli were clearly visualized by dynamic enhanced MR lymphangiography, thus allowing for management with thoracic duct embolization.