• Title/Summary/Keyword: Lung, neoplasms

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A Case of Organizing Pneumonia Associated with FOLFIRI Chemotherapy

  • Lee, Yoon Jeong;Kim, Jun-Hyun;Kim, Sun Woong;Kang, Won Chan;Kim, Soo Jung;Kim, Ji Hye;Kim, Sun Jong
    • Tuberculosis and Respiratory Diseases
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    • v.77 no.6
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    • pp.262-265
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    • 2014
  • The combination chemotherapy of irinotecan with 5-fluorouracil and leucovorin (FOLFIRI regimen) was recently proven to be beneficial in patients with advanced colorectal cancer. Pulmonary toxicity is very rare in adverse effects of irinotecan. No case of organizing pneumonia (also known as bronchiolitis obliterans organizing pneumonia) associated with FOLFIRI chemotherapy has been reported. We experienced a case of a 62-year-old man who presented persistent dry cough and progressive dyspnea after receiving chemotherapy with FOLFIRI regimen. After surgical lung biopsy, the patient was diagnosed with FOLFIRI chemotherapy-induced organizing pneumonia which was successfully treated with steroid therapy.

A Clinical Study on 29 Cases of Vocal Cord Paralysis caused by Neoplasm (종양에 의한 성대마비 29예에 대한 임상적 고찰)

  • 김광문;김영호;최홍식;홍원표;김창규;권오휘
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.5 no.1
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    • pp.59-63
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    • 1994
  • The authors observed the clinical status of 29 patients with vocal cord paralysis caused by tumor from April, 1983 to September, 1993 at Department of Otorhinolaryngology, Yongdong Severance hospital, Yonsei University College of Medicine. The results were as follows: 1) In the kinds of neoplasms, the most frequent were lung Ca. with 13 cases(44.8%), followed by 8 cases by thyroid Ca., 3 cases by neurogenic tumor, 2 cases by mediastinum tumor, cervical esophagus Ca., tracheal Ca., glomus jugulare were 1 case each. 2) In sex distribution, there were 18 cases of males and 11 cases of females with the male to female ratio being 1.8:1. In age distribution, most of the cases(10 cases ; 34.5%) were in the 7th decade. 3) In chief complaints, most of the cases(17 cases : 58.6%) had hoarseness only and aspiration, stridor, dyspnea, cough, dysphagia were present in some cases. 4) In site of the paralysed vocal cord, 21 cases were in the left cord. 5 cases in the right cord and 3 cases in the both cords. 5) In the position of paralysed vocal cord, most of the cases(23 cases : 79.3%) were in the parmedian position.

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Endobronchial Chondroid Hamartoma Removed by Segmentectomy -Surgical Experience of One Case - (폐구역절제술로 제거된 기관지 내 연골성 과오종 -수술치험 1예 -)

  • Cho, Seong-Ho;Park, Sung-Dal
    • Journal of Chest Surgery
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    • v.38 no.9 s.254
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    • pp.652-655
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    • 2005
  • In comparison to parenchymal hamartoma, endobronchial hamartoma is rare benign neoplasm of the lung. Most parenchymal hamariomas are asymptomatic and are found incidentally. However, endobronchial hamartomas are frequently discovered through respiratory symptoms as a result of bronchial irritation or obstruction. A 47-year-old male patient was admitted to our hospital due to dry cough f month prior to admission. On bronchoscopic examination, a polypoid mass was found completely obliterating the anterior segmental bronchus of the left upper lobe. We report a case of endobronchial chondroid hamartoma, which was resected by anterior segmentectomy of the left upper lobe.

Epithelioid Hemangioendothelioma of the Spinal Cord - A Case Report - (척수에 발생한 상피양 혈관내피종 1예 - 증례보고 -)

  • Kim, Ki Tai;Won, You Sam;Lee, Seung Min;Yang, Jae Young;Choi, Chun Sik;Ju, Mun Bae;Keum, Joo Seob
    • Journal of Korean Neurosurgical Society
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    • v.30 no.5
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    • pp.627-632
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    • 2001
  • Hemangioendotheliomas are vascular neoplasms characterized by histologic appearance that are intermediate between hemangiomas and angiosarcomas first described by Weiss and Enzinger in 1982. They are classified into at least 3 subgroups, including epithelioid hemangioendothelioma, spindle cell hemangioendothelioma, and malignant endovascular angioendothelioma, and have been reported principally in soft tissues of the extremities, lung, liver, and bone. The cases involving the central nervous system reported are very rare. We report an intraspinal epithelioid hemangioendothelioma occurring in a 52-year-old man. To our knowledge, it is first case of spinal hemangioendothelioma in Korea.

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Multiple Extracranial Metastases of Atypical Meningiomas

  • Lee, Gyu-Chan;Choi, Seung-Won;Kim, Seon-Hwan;Kwon, Hyon-Jo
    • Journal of Korean Neurosurgical Society
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    • v.45 no.2
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    • pp.107-111
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    • 2009
  • Meningiomas are usually benign neoplasms in which extracranial metastases occur very rarely. We report a case of multiple extracranial metastases of an atypical meningioma following a local recurrence. A 68-year-old man presented with left-side motor weakness and dysarthria for two weeks. A computed tomography (CT) scan and magnetic resonance imaging (MRI) showed an intraventricular tumor. We performed a total mass removal, and the histopathologic findings were consistent with benign meningioma. Eight months later, the meningioma recurred. We performed a reoperation and whole brain radiation therapy postoperatively. The histopathologic findings showed atypical meningioma. Six months later, CT and MRI revealed metastases to multiple vertebrae, lung, ribs and perirenal soft tissue so a decompressive laminectomy with mass removal was performed. The histopathologic findings of the spinal tumors showed atypical meningioma. The results from perirenal biopsies were consistent with metastatic meningioma. In conclusion, extracranial metastasis as well as local recurrence must be considered in atypical or anaplastic meningioma. There must be regular follow-ups. Finally, an evaluation of the chest, abdomen and bone is necessary, especially when related symptoms or signs develop.

Synovial Sarcoma Arising from the Chest Wall in a Child (소아의 흉벽에서 발생한 윤활막 육종)

  • Kim, Seok;Park, Ki-Sung;Bae, Chi-Hoon
    • Journal of Chest Surgery
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    • v.43 no.4
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    • pp.470-473
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    • 2010
  • Synovial sarcoma is a malignant soft-tissue tumor that most commonly occurs in the extremities of young adults. There have been several cases of synovial sarcomas of the pleural and lung reported, but synovial sarcoma arising from the chest wall in childhood is very rare. Here we report a case of synovial sarcoma arising from the chest wall in a 3 year-old female patient. The tumor was completely resected. No adjuvant therapy was given. The patient is well 3 years after the operation.

Reliability and Validity of the Korean Version of the Cancer Stigma Scale

  • So, Hyang Sook;Chae, Myeong Jeong;Kim, Hye Young
    • Journal of Korean Academy of Nursing
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    • v.47 no.1
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    • pp.121-132
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    • 2017
  • Purpose: In this study the reliability and validity of the Korean version of the Cancer Stigma Scale (KCSS) was evaluated. Methods: The KCSS was formed through translation and modification of Cataldo Lung Cancer Stigma Scale. The KCSS, Psychological Symptom Inventory (PSI), and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire - Core 30 (EORTC QLQ-C30) were administered to 247 men and women diagnosed with one of the five major cancers. Construct validity, item convergent and discriminant validity, concurrent validity, known-group validity, and internal consistency reliability of the KCSS were evaluated. Results: Exploratory factor analysis supported the construct validity with a six-factor solution; that explained 65.7% of the total variance. The six-factor model was validated by confirmatory factor analysis (Q (${\chi}^2/df$)= 2.28, GFI=.84, AGFI=.81, NFI=.80, TLI=.86, RMR=.03, and RMSEA=.07). Concurrent validity was demonstrated with the QLQ-C30 (global: r=-.44; functional: r=-.19; symptom: r=.42). The KCSS had known-group validity. Cronbach's alpha coefficient for the 24 items was .89. Conclusion: The results of this study suggest that the 24-item KCSS has relatively acceptable reliability and validity and can be used in clinical research to assess cancer stigma and its impacts on health-related quality of life in Korean cancer patients.

A Rare Presentation of Metastasis of Prostate Adenocarcinoma to the Stomach and Rectum

  • Soe, Aye Min;Bordia, Sonal;Xiao, Philip Q.;Lopez-Morra, Hernan;Tejada, Juan;Atluri, Sreedevi;Krishnaiah, Mahesh
    • Journal of Gastric Cancer
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    • v.14 no.4
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    • pp.271-274
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    • 2014
  • Prostate cancer is the second most common cause of cancer death in men in the United States. The most common sites of metastasis include the bone, lymph nodes, lung, liver, pleura, and adrenal glands, whereas metastatic prostate cancer involving the gastrointestinal tract has been rarely reported. A 64-year-old African-American man with a history of prostate cancer presented with anemia. He reported the passing of dark colored stools but denied hematemesis or hematochezia. Colonoscopy revealed circumferential nodularity, and histology demonstrated metastatic carcinoma of the prostate. Esophagogastroduodenoscopy showed hypertrophic folds in the gastric fundus, and microscopic examination revealed tumor cells positive for prostate-specific antigen. Bone scanning and computed tomography of the abdomen and pelvis did not show metastasis. It is crucial to distinguish primary gastrointestinal cancer from metastatic lesions, especially in patients with a history of cancer at another site, for appropriate management.

A Case of Invasive Thymoma with Endotracheal Polypoid Growth

  • Hwang, Jin Tae;Kim, Min Hee;Chang, Ki Jun;Chang, Hyo Jeong;Choi, Soo Jeon;Yuh, Young Jin;Kim, Jung Yeon;Park, Hye Kyeong
    • Tuberculosis and Respiratory Diseases
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    • v.73 no.6
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    • pp.331-335
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    • 2012
  • Thymomas are one of the most common neoplasms of the mediastinum derived from thymic epithelium. It is common that invasive thymoma invades the lung, pericardium, and great vessels. Airway compression by mass effect also occurs, but direct polypoid tumor growth into the airway is extremely rare. Only 20 cases of invasive thymoma with endobronchial polypoid growth have previously been reported globally. However, there is no case report of invasive thymoma with endotracheal growth. Herein, we report a rare case of invasive thymoma with endotracheal polypoid growth in a 28-year-old woman.

Primary Pulmonary Carcinoma Ex-pleomorphic Adenoma of the Salivary Gland Type (일차성 폐의 침샘형 악성 다형선종)

  • Park, Sang-Jun;Cho, Sung-Woo;Lee, Hee-Sung
    • Journal of Chest Surgery
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    • v.43 no.2
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    • pp.217-220
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    • 2010
  • Pleomorphic adenoma is also called a mixed tumor and it most commonly occurs in the salivary gland. This neoplasm has a low grade malignant potential, but it may also show aggressive clinical behavior like recurrence or metastasis. We report here on a case of a tumor that was confirmed to be primary pulmonary carcinoma ex-pleomorphic adenoma by the pathologic examination after complete resection, and it had the characteristics of malignant neoplasms, such as multiple metastases.