• Title/Summary/Keyword: Lp-$PLA_2$ inhibition assay

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Antiarteriosclerosis Effects of Black Rices Extract (흑미 추출물에 대한 항동맥경화 효과(Notes))

  • Lim, Chi-Hwan;Kim, Jong-Min;Baek, Seung-Hwa
    • Journal of Society of Preventive Korean Medicine
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    • v.12 no.3
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    • pp.91-98
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    • 2008
  • 80% MeOH extract of black rices fractionated with n-hexane, EtOAc, and n-BuOH. Copper-induced LDL oxidation inhibition assay and ACAT inhibition assay examined with fractions. n-Hexane and EtOAc fractions showed high inhibition activity. We divided n-hexane fraction into three sub-layers(H1 - H3) and EtOAc into eight sub-layers(E1 - E8). H1, H2, E6, and E7 are showed higher inhibition activity than standard in Lp-PLA2 inhibition assay and H1 and E6 are showed higher ACAT inhibition activity than standard.

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Antioxidative and $Lp-PLA_2$ Inhibitory Activities in 29 Fruits and Vegetables (시중 유통 과일 및 채소류 29종의 항산화 효과 및 $Lp-PLA_2$ 활성 저해 연구)

  • Kim, Ji-Young;Lee, Cho-Rong;Cho1, Kyung-Hyun;Lee, Jeung-Hee;Lee, Ki-Teak
    • Food Science and Preservation
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    • v.16 no.4
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    • pp.512-517
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    • 2009
  • Total phenolic content and the antioxidative activity (DPPH radical-scavenging capacity) of 29 fruits and vegetables were determined. The total phenolic contents of plum (1.06 mg GAE/g fresh weight) and cherry (0.95 mg GAE/g fresh weight) were high, whereas those of banana, carrot, and cucumber (each at 0.07 mg GAE/g fresh weight) were low. In the DPPH radical-scavenging assay, apple mango extract showed the highest value(92.8%) among the 29 ethanol extracts tested, followed by paprika (75.4%), beet (75.3%), and cherry (75.1%). In the $Lp-PLA_2$ inhibition assay, cherry (34.95% inhibition) and grape (31.03%) showed the highest $Lp-PLA_2$ activities among the 29 fruits and vegetables examined.