• 한국운동역학회지
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• 제19권4호
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• pp.637-645
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• 2009

이 연구는 여성노인의 태권에어로빅스 12주 훈련 후 앞굽이 몸통지르기 동작시 하지관절의 생체역학적 변화를 구명하는 것이다. 대상자는 여성노인 10명이 참여하였으며 카메라(MCU-240) 7대와 지면반력기(Kist1er-9286AA) 2대를 이용하여 데이터를 수집하였다. 유의수준 .10에서 운동전 후 차이는 다음과 같다. 첫째, 최소 관절각의 변화는 발목의 저측/배측굴곡(왼쪽, $p=0.001^*$), 외번/내번(양쪽, $p=0.009^*$, $p=0.04^*$)과 무릎의 외전/내전(왼쪽, $p=0.04^*$) 및 엉덩이의 내측/외측 회전(양쪽, $p=0.07^*$, $p=0.02^*$)에서 통계적으로 유의하게 나타났다. 둘째, 최대 관절모멘트 변화는 발목관절의 외번/내번 모멘트(양쪽, $p=0.05^*$, $p=0.05^*$), 무릎관절의 외전/내전 모멘트(왼쪽, $p=0.08^*$) 및 엉덩이관절의 내측/외측 회전 모멘트(오른쪽, $p=0.09^*$)가 통계적으로 유의하게 나타났다. 셋째, 최대 관절파워의 변화는 엉덩이관절의 굴곡/신전(양쪽, $p=0.05^*$, $p=0.01^*$)과 내전/외전(양쪽, $p=0.02^*$, $p=0.00^*$) 및 무릎의 내전/외전(왼쪽, $p=0.00^*$) 파워가 통계적으로 유의한 차이를 보였다. 결론적으로 태권에어로빅스 몸통지르기동작이 여성노인들의 하지 관절에 부분적인 생체변화를 일으켰다.

• 한국운동역학회지
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• 제20권4호
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• pp.395-406
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• 2010

The purpose of this study was to analyze the changes in kinematic and kinetic parameters of lower extremity joint according to rehabilitation period. Fourteen collegiate male athletes(age: $22.1{\pm}1.35$ years, height: $182.46{\pm}9.45cm$, weight: $88.63{\pm}9.25kg$) and fourteen collegiate athletes on functional ankle instability(age: $21.5{\pm}1.35$ years, height: $184.45{\pm}9.42cm$, weight: $92.85{\pm}10.85kg$) with the right leg as dominant were chosen. The subjects performed drop landing. The date were collected by using VICON with 8 camera to analyze kinematic variables and force platform to analyze kinetic variables. There are two approaches of this study, one is to compare between groups, the other is to find changes of lower extremity joint after rehabilitation. In comparison to the control group, FAI group showed more increased PF & Inversion at IC and decreased full ROM when drop landing. Regarding the peak force and loading rate, it resulted in higher PVGRF and loading. FAI group used more increased knee and hip ROM because of decreased ankle ROM to absorb the shock. And it used sagittal movement to stabilize. In terms of rehabilitation period, FAI group showed that landing patterns were changed and it increased total ankle excursion and used all lower extremity joint close to normal ankle. Regarding the peak force and loading rate, FAI group decreased PVGRF and loading rate. and also showed shock absorption using increased ankle movement. And COP variable showed that proprioception training increased stability during 8 weeks. The results of this study suggest that 8 weeks rehabilitation period is worthwhile to be considered as a way to improve neuromuscular control and to prevent sports injuries.

• Biomolecules & Therapeutics
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• 제26권3호
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• pp.298-305
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• 2018

Rhomboid family member 2 gene (Rhbdf2) is an inactive homologue lacking essential catalytic residues of rhomboid intramembrane serine proteases. The protein is necessary for maturation of tumor necrosis factor-alpha ($TNF-{\alpha}$) converting enzyme, which is the molecule responsible for the release of $TNF-{\alpha}$. In this study, Rhbdf2 knockout (KO) mice were produced by CRISPR/CAS9. To see the effects of the failure of $TNF-{\alpha}$ release induced by Rhbdf2 gene KO, collagen-induced arthritis (CIA), which is the representative $TNF-{\alpha}$ related disease, was induced in the Rhbdf2 mutant mouse using chicken collagen type II. The severity of the CIA was measured by traditional clinical scores and histopathological analysis of hind limb joints. A rota-rod test and grip strength test were employed to evaluate the severity of CIA based on losses of physical functions. The results indicated that Rhbdf2 mutant mice showed clear alleviation of the clinical severity of CIA as demonstrated by the significantly lower severity indexes. Moreover, a grip strength test was shown to be useful for the evaluation of physical functional losses by CIA. Overall, the results showed that the Rhbdf2 gene has a significant effect on the induction of CIA, which is related to $TNF-{\alpha}$.