• 문화기술의 융합
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• 제4권3호
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• pp.253-259
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• 2018

떫은감 자원은 전통적으로 다방면의 여러 조직학적 질병을 치료하고 모발 성장을 비롯한 다양한 생물학적 활성에 매우 높은 효과가 있음이 알려져 왔다. 본 연구는 대머리 패턴의 검은 쥐 모델에 유전적으로 입증된 떫은감 추출물에 대한 발모 및 탈모방지 효능을 알아보고자 하였다. 표준화된 제형을 사용하여 대조군, 떫은감 추출물(10 mg/mouse/day)과 양성대조군인 미녹시딜(2 %)을 매일 두번씩 모발이 성장할 때까지 매일 등 피부에 일정량씩 도포 투여하여 조사하였다. C57BL/ 6 Black 쥐에서 모발 성장 세대를 통해 모발 성장의 변화 패턴이 관찰되었다. 모발 존재 면적과 모발의 길이는 처리 대조군 마우스 보다 떫은감 처리 마우스 처리구에서 유의하게 증가 하였다 (P>0.001). 또한 조직학적 평가에서도 대조군과 비교하여 떫은감 추출물의 처리구에서 모낭세포의 숫자가 현저하게 증가하였다. 따라서 본 실험 결과를 통하여 떫은감 추출물을 피부 도포시 누드 마우스의 모발 성장을 촉진하고 모발의 존재 영역을 확장시키고 모발 길이를 증가시켜 장기 모발 성장기의 지표가 될 수 있음을 알 수 있었다.

• 한국농공학회논문집
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• 제48권5호
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• pp.51-60
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• 2006

In order to examine the heat transfer characteristic of a soil warming system and effects of soil warming on the greenhouse heating load, control experiments were performed in two greenhouses covered with double polyethylene film. One treated the soil warming with an electric heat wire and the other treated a control. Inside and outside air temperature, soil temperature and heat flux, and heating energy consumption were measured under the set point of heating temperature of $5,\;10,\;15,\;and\;20^{\circ}C$, respectively. Soil temperatures in a soil warming treatment were observed $4.1\;to\;4.9^{\circ}C$ higher than a control. Heating energy consumptions decreased by 14.6 to 30.8% in a soil warming treatment. As the set point of heating temperature became lower, the rate of decrease in the heating energy consumptions increased. The percentage of soil heat flux in total heating load was -49.4 to 24.4% and as the set point of heating temperature became higher, the percentage increased. When the set point of heating temperature was low in a soil warming treatment, the soil heat flux load was minus value and it had an effect on reducing the heating load. Soil heat flux loads showed in proportion to the air temperature difference between the inside and outside of greenhouse but they showed big difference according to the soil warming treatment. So new model for estimation of the soil heat flux load should be introduced. Convective heat transfer coefficients were in proportion to the 1/3 power of temperature difference between the soil surface and the inside air. They were $3.41\;to\;12.42\;W/m^{2}^{\circ}C$ in their temperature difference of $0\;to\;10^{\circ}C$. Radiative heat loss from soil surface in greenhouse was about 66 to 130% of total heating load. To cut the radiation loss by the use of thermal curtains must be able to contribute for the energy saving in greenhouse.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2008년도 학술발표회 논문집
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• pp.1295-1299
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• 2008

Soil erosion is a natural process and has been occurring in most areas in the watershed. However, accelerated soil erosion rates have been causing numerous environmental impacts in recent years. To reduce soil erosion and sediment inflow into the water bodies, site-specific soil erosion best management practices (BMPs) need to be established and implemented. The most commonly used soil erosion model is the Universal Soil Loss Equation (USLE), which have been used in many countries over 30 years. The Sediment Assessment Tool for Effective Erosion Control (SATEEC) ArcView GIS system has been developed and enhanced to estimate the soil erosion and sediment yield from the watershed using the USLE input data. In the last decade, the Soil and Water Assessment Tool (SWAT) model also has been widely used to estimate soil erosion and sediment yield at a watershed scale. The SATEEC system estimates the LS factor using the equation suggested by Moore and Burch, while the SWAT model estimates the LS factor based on the relationship between sub watershed average slope and slope length. Thus the SATEEC and SWAT estimated soil erosion values were compared in this study. The differences in LS factor estimation methods in the SATEEC and SWAT caused significant difference in estimated soil erosion. In this study, the difference was -51.9%(default threshold)$\sim$-54.5%(min. threshold) between SATEEC and non-patched SWAT, and -7.8%(default threshold)$\sim$+3.8%(min. threshold) between SATEEC and patched SWAT estimated soil erosion.

• 한국농공학회논문집
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• 제50권1호
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• pp.3-12
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• 2008

Soil erosion is a natural process and has been occurring in most areas in the watershed. However, accelerated soil erosion rates have been causing numerous environmental impacts in recent years. To reduce soil erosion and sediment inflow into the water bodies, site-specific soil erosion best management practices(BMPs) need to be established and implemented. The most commonly used soil erosion model is the Universal Soil Loss Equation(USLE), which have been used in many countries over 30 years. The Sediment Assessment Tool for Effective Erosion Control(SATEEC) ArcView GIS system has been developed and enhanced to estimate the soil erosion and sediment yield trom the watershed using the USLE input data. In the last decade, the Soil and Water Assessment Tool(SWAT) model also has been widely used to estimate soil erosion and sediment yield at a watershed scale. The SATEEC system estimates the LS factor using the equation suggested by Moore and Burch, while the SWAT model estimates the LS factor based on the relationship between sub watershed average slope and slope length. Thus the SATEEC and SWAT estimated soil erosion values were compared in this study. The differences in LS factor estimation methods in the SATEEC and SWAT caused significant difference in estimated soil erosion. In this study, the difference was -51.9%(default threshold)${\sim}-54.5%$(min. threshold) between SATEEC and non-patched SWAT, and -7.8%(default threshold)${\sim}+3.8%$(min. threshold) between SATEEC and patched SWAT estimated soil erosion.

• 수산해양기술연구
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• 제52권4호
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• pp.290-298
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• 2016

This study aims to reduce the force exerted to the buoy of the gillnet by wave and current. Five buoy models were selected for experiments and their rope tensions under wave and current action were compared. Five models were EL (ellipsoid), EL-H (ellipsoid-hole), SL (streamlined body), SP (sphere) and CL (cylinder, traditional type). In the first experiment, the Five models were tested without any attachment. In the second experiment, a flagpole was attached to each model. As a result, in the condition without flagpole, the tensions of four models with the exception of the CL were about a half of that of the CL. In the condition with flagpole, the tension of all models was twice larger than that without flagpole. Thus, a new model was suggested to improve the problem, which has a combined body that of a flagpole and a buoy Three new models of CL-L (long and thin cylinder), LF (leaf shape) and LF-F (leaf shape with fin) were designed. Also a cylinder type (CLD) with a flagpole as a control was included in the experiment. As a result, the LF-F had the smallest tension and a half tension of the CLD. Therefore, it is supposed that the flagpole and buoy combined model could reduce the tension on buoy rope and contribute to improve the gillnet loss problem.

• 한국콘텐츠학회논문지
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• 제13권4호
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• pp.361-375
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• 2013

최근 모바일 애플리케이션 시장이 지속적인 성장을 하고 있는 반면 유료 모바일 애플리케이션의 수익성은 저하되고 있다. 심화된 경쟁으로 인하여 유료 모바일 애플리케이션의 가격은 지속적으로 하락하는 추세이며 사용자의 유료 모바일 애플리케이션 구입이 줄어들고 있는 추세이다. 그러나 기존 연구는 모바일 애플리케이션의 수용에만 초점을 맞추고 있어 유료 모바일 애플리케이션의 수용 저항과 같은 현상을 제대로 설명하고 있지 못한 상황이다. 이에 본 연구에서는 유료 모바일 애플리케이션에 대해 사용자의 수용 저항 요인을 분석하고자 한다. 이를 위해, 본 연구에서는 Stimulus-Organism-Response 모델을 기초로 유료 모바일 애플리케이션의 특성과 사회적 영향(Stimulus)이 사용자에게 지각된 손실과 지각된 혜택(Organism)으로 인지되어 애플리케이션 수용저항(Response)에 어떻게 영향을 미치는지를 검증하였다. 그 결과 유료 모바일 애플리케이션이 확산되지 못하고 소멸되는 현상이 지각된 손실 때문임을 설명하고 이러한 지각된 손실을 낮추기 위해 모바일 애플리케이션 개발시 초기 가격을 낮추고 부정적인 리뷰에 대해 적극적으로 대응해야 한다는 방향성을 제시하였다. 또한 개인적인 특성을 통제변수로 연구모형에 포함하여 자기효능감이 앱 수용저항을 낮출수 있다는 점을 검증하였다.

• Molecules and Cells
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• 제41권7호
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• pp.646-652
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• 2018

Neurodegeneration can result in memory loss in the central nervous system (CNS) and impairment of taste and smell in the peripheral nervous system (PNS). The neurodegeneration seen in Parkinson's disease (PD) is characterized by functional loss of dopaminergic neurons. Recent studies have also found a role for dopaminergic neurons in regulating taste memory rewards in insects. To investigate how taste memories and sugar sensitivity can be affected in PD, we utilized the $DJ-1{\beta}$ mutant fruit fly, $DJ-1{\beta}^{ex54}$, as a PD model. We performed binary choice feeding assays, electrophysiology and taste-mediated memory tests to explore the function of the $DJ-1{\beta}$ gene in terms of sugar sensitivity as well as associative taste memory. We found that PD flies exhibited an impaired ability to discriminate sucrose across a range of sugar concentrations, with normal responses at only very high concentrations of sugar. They also showed an impairment in associative taste memory. We highlight that the taste impairment and memory defect in $DJ-1{\beta}^{ex54}$ can be recovered by the expression of wild-type $DJ-1{\beta}$ gene in the dopaminergic neurons. We also emphasized the role of dopaminergic neurons in restoring taste memory function. This impaired memory property of $DJ-1{\beta}^{ex54}$ flies also allows them to be used as a model system for finding supplementary dietary foods that can improve memory function. Here we provide evidence that the associative taste memory of both control and $DJ-1{\beta}^{ex54}$ flies can be enhanced with dietary supplementation of the medicinal plant, omija.

• Journal of Electrical Engineering and Technology
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• 제9권5호
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• pp.1471-1481
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• 2014

This paper presents the new power dissipation model of individual switching device in a high-level modular multilevel converter (MMC), which can be mostly used in voltage sourced converter (VSC) based high-voltage direct current (HVDC) system and flexible AC transmission system (FACTS). Also, the voltage balancing method based on sorting algorithm is newly proposed to advance the MMC functionalities by effectively adjusting switching variations of the sub-module (SM). The proposed power dissipation model does not fully calculate the average power dissipation for numerous switching devices in an arm module. Instead, it estimates the power dissipation of every switching element based on the inherent operational principle of SM in MMC. In other words, the power dissipation is computed in every single switching event by using the polynomial curve fitting model with minimum computational efforts and high accuracy, which are required to manage the large number of SMs. After estimating the value of power dissipation, the thermal condition of every switching element is considered in the case of external disturbance. Then, the arm modeling for high-level MMC and its control scheme is implemented with the electromagnetic transient simulation program. Finally, the case study for applying to the MMC based HVDC system is carried out to select the appropriate insulated-gate bipolar transistor (IGBT) module in a steady-state, as well as to estimate the proper thermal condition of every switching element in a transient state.

• Journal of Korean Biological Nursing Science
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• 제23권3호
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• pp.199-207
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• 2021

Purpose: The purpose of this study was to investigate effects of NXP031, an inhibitor of oxidation by specifically binding to the complex of DNA aptamer/vitamin C, on dopaminergic neurons loss and the reaction of microglia in an animal model of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced subchronic Parkinson's disease (PD). Methods: A subchronic PD mouse model was induced via an intraperitoneal (IP) injection of MPTP 30 mg/kg per day for five days. NXP031 (vitamin C/aptamer at 200 mg/4 mg/kg) and vitamin C at 200 mg/kg were administered via IP injections at one hour after performing MPTP injection. This process was performed for five days. Motor function was then evaluated with pole and rotarod tests, after which an immunohistochemical analysis was performed. Results: NXP031 administration after MPTP injection significantly improved motor functions (via both pole and rotarod tests) compared to the control (MPTP injection only) (p<.001). NXP031 alleviated the loss of dopaminergic neurons in the substantia nigra (SN) and striatum caused by MPTP injection. It was found to have a neuroprotective effect by reducing microglia activity. Conclusion: NXP031 can improve impaired motor function, showing neuroprotective effects on dopaminergic neurons in the SN and striatum of MPTP-induced subchronic Parkinson's disease mouse model. Results of this study suggest that NXP031 has potential in future treatments for PD and interventions for nerve recovery.

• 한국습지학회지
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• 제23권2호
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• pp.173-182
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• 2021

수자원의 보전과 관리를 위해서는 갈수시의 유량감쇄 특성을 파악하는 것이 중요한 과제 중에 하나이다. 감쇄특성을 하천 유량자료를 이용하여 표현하기 위해서 여러 복잡한 특성을 고려하여야 하므로, 편의성을 위하여 선형 감쇄분석이 주로 적용되어 왔다. 그러나, 최근의 연구에서 제시된 지하수 유출과 비피압대수층의 저장능력의 비선형성을 고려하면, 비선형 감쇄모형의 적용성이 더 높다고 할 수 있다. 따라서, 본 연구의 목적은 유출자료를 이용하여 지하수의 증발손실, 저류 및 재함양과 같은 비선형 특성을 고찰하는 데 있다. 한강의 상류인 평창강 유역의 유출자료를 이용하여 분석을 수행하였으며, 지하수 수지를 구성하는 주요한 요소인 지하수 유출, 증발손실, 저류, 재함양에 대해서 고찰하고 정량화하였다. 연구결과에 따라서, 식생에 의한 지하수 손실이 감쇄곡선을 편향시키는 것으로 나타났다. 또한, 계절적 강우와 잠재증발산 경향을 감쇄분석에 적용하여 월별 증발산 손실과 지하수 함양량을 정량화하여 제시하였다.