• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.4953-4960
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• 2013

Primary liver cancer is one of the most common cancers at the global level, accounting for half of all cancers in some undeveloped countries. This disease tends to occur in livers damaged through alcohol abuse, or chronic infection with hepatitis B and C, on a background of cirrhosis. Various cancer-causing substances are associated with primary liver cancer, including certain pesticides and such chemicals as vinyl chloride and arsenic. The strong association between HBV infection and liver cancer is well documented in epidemiological studies. It is generally acknowledged that the virus is involved through long term chronic infection, frequently associated with cirrhosis, suggesting a nonspecific mechanism triggered by the immune response. Chronic inflammation of liver, continuous cell death, abnormal cell growth, would increase the occurrence rate of genetic alterations and risk of disease. However, the statistics indicated that only about one fifth of HBV carries would develop HCC in lifetime, suggesting that individual variation in genome would also influence the susceptibility of HCC. The goal of this review is to highlight present level of knowledge on the role of viral infection and genetic variation in the development of liver cancer.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제10권12호
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• pp.5307-5327
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• 2016

Restricted by finite battery energy, traditional wireless sensor networks (WSNs) can only maintain for a limited period of time, resulting in serious performance bottleneck in long-term deployment of WSN. Fortunately, the advancement in the wireless energy transfer technology provides a potential to free WSNs from limited energy supply and remain perpetual operational. A mobile charger called wireless charging vehicle (WCV) is employed to periodically charge each sensor node and keep its energy level above the minimum threshold. Aiming at maximizing the ratio of the WCV's vocation time over the cycle time as well as guaranteeing the perpetual operation of networks, we propose a feasible and optimal solution to this issue within the context of a real-time large-scale deployed WSN. First, we develop two different types of charging cycles: initialization cycles and renewable cycles and give relevant algorithms to construct these two cycles for each sensor node. We then formulate the optimization problem into an optimal construction algorithm and prove its correctness through theoretical analysis. Finally, we conduct extensive simulations to demonstrate the effectiveness of our proposed algorithms.

• 한국표면공학회지
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• 제49권1호
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• pp.87-91
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• 2016

The development of high performance transparent electrode with flexibility have been required for flexible electronics. Here, we demonstrate the silver nanowire and reduced graphene oxide hybrid transparent electrode for replacing brittle indium-tin-oxide electrode by spray coating technique and plasma reduction. The spray coating system is applied to deposit silver nanowire and over coated graphene oxide films and it has a great potential to scale-up. The resistance of silver nanowire transparent electrode is reduced by 10% and the surface roughness is decreased after graphene oxide coating. The over-coated graphene oxide is successfully reduced by $H_2$ plasma treatment and it is effective in increasing the environmental stability of electrode. The lifetime of silver nanowire and reduced graphene oxide hybrid electrode at $85^{\circ}C$ of Celsius degree of temperature and 85% of relative humidity has much increased.

• 한국가스학회지
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• 제7권2호
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• pp.1-6
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• 2003

본 연구에서는 이미 개발되어 있는 부식결함의 잔존강도를 평가식을 이용하여 파단, 대누출, 소누출의 손상모드 예측하는 절차를 제시하였다. 또한 이 손상모드에 따라 손상확률을 예측할 수 있는 방법을 제시하고 여기에 부식속도 정보를 결합하면 일정기간 경과 후 손상확률도 예측할 수 있음을 보였다. 이 결과는 노후배관의 수명 또는 교체주기의 예측에 매우 유용하게 활용될 수 있을 것이라 판단된다.

• Nutrition Research and Practice
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• 제13권6호
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• pp.461-472
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• 2019

BACKGROUND/OBJECTIVES: Globally, it has been projected that there will be 2 billion overweight and 1 billion obese individuals by 2030. In Korea, the prevalence of adult obesity (BMI > 25) increased from 29.7% in 2009 to 32.4% in 2015. Moreover, childhood obesity, which leads to adulthood obesity, has increasingly become a social problem. The purpose of this review is to summarize the scientific basis for the development of effective models and policies aimed at preventing obesity over a lifetime based on research modeling obesogenic environments. MATERIALS/METHODS: The review focuses on the characteristics of obesity prevalence and trends in 3P analysis (papers, patents, and products) as well as government-funded projects in Korean obesity obesogenic environments over the last 10 years. RESULTS AND DISCUSSION: As a result of the 3P analysis, studies on obesity risk factors were frequently carried out, according to two data bases RISS (4.9%) and PubMed (24.7%). Since there were only 17% patents related to the mechanism of preventing obesity in 7,951 Korean patents related to obesity, new paradigms of technologies to dominate the global obesity markets are needed. After government-funded projects were analyzed, communication and cooperation in multi-governmental departments were suggested to elucidate the characteristics of Korean obesity. Government should also produce short- and long-term road maps to develop a practical, successful outcome. Although the rate of obesity in Korea is currently lower than in other developed countries according to WHO criteria, without adequate governmental intervention, obesity rates will approach those of the top countries with high incidence rates of obesity within the next 10 years.

• 한국재료학회지
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• 제32권8호
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• pp.339-344
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• 2022

The lattice oxygen mechanism (LOM) is considered one of the promising approaches to overcome the sluggish oxygen evolution reaction (OER), bypassing -OOH^* coordination with a high energetic barrier. Activated lattice oxygen can participate in the OER as a reactant and enables O^*-O^* coupling for direct O₂ formation. However, such reaction kinetics inevitably include the generation of oxygen vacancies, which leads to structural degradation, and eventually shortens the lifetime of catalysts. Here, we demonstrate that Se incorporation significantly enhances OER performance and the stability of NiFe (oxy)hydroxide (NiFe) which follows the LOM pathway. In Se introduced NiFe (NiFeSe), Se forms not only metal-Se bonding but also Se-oxygen bonding by replacing oxygen sites and metal sites, respectively. As a result, transition metals show reduced valence states while oxygen shows less reduced valence states (O^-/O₂^2-) which is a clear evidence of lattice oxygen activation. By virtue of its electronic structure modulation, NiFeSe shows enhanced OER activity and long-term stability with robust active lattice oxygen compared to NiFe.

• Nuclear Engineering and Technology
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• 제56권6호
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• pp.2388-2394
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• 2024

In our previous works, two different spherical burnable poison particles (BPPs) as B₄C and Gd₂O₃ in pin-in block type HTGR core had utilized to suppress the excess reactivity and to control long-term reactivity during the burnup period. In the present work, we performed the neutronic analysis of a prismatic HTGR operating at 850 ℃ with thermal power of 100 MW containing spherical and cylindrical BPPs and then studied the self-shielding effect of BPPs and shape effect. The calculations were performed when the surface area (1) or volume (2) of cylindrical BPPs equals to that of the spherical BPPs. The calculations showed that the neutronic parameters were slightly better for the second case than the first one, such as the excess reactivity of the reactor core at the beginning of the cycle were more suppressed, the core lifetime were more extended, and the fuel-burning were more efficiently. The neutron spectrum in each region of the cylindrical BBPs slightly differs than that of the spherical BPPs. Therefore, the self-shielding effect of BPPs on reactor core performance depends on the particle's geometrical shape.

• 방사성폐기물학회지
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• 제6권2호
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• pp.155-162
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• 2008

후행 핵연료주기 경제성 평가는 추정 비용의 불확실성, 평가 대상기간의 장기성, 적용 할인율에 따른 계산결과의 변동성 등 많은 불확실성을 내포하고 있기 때문에 평가기관 또는 평가자에 따라 그 결과가 서로 상이하다. 본고에서는 지금까지 수행 된 주요 경제성 평가 연구들을 조사/분석하여 그 특징과 한계를 알아봄으로써 현재 국내에서 추진되고 있는 사용후핵연료 공론화 및 후행 핵연료주기 정책 연구 추진에 기초자료로 활용될 수 있도록 하고자 하였다. 분석 결과 사용후핵연료 재활용 옵션에 비해 직접처분 옵션이 유리하나, 입력 자료로 사용된 파라미터 값에 따라 결과의 불확실성이 많이 나타나 이 부분에 대한 추가적인 연구가 필요하다는 사실을 알 수 있었다.

• 정보처리학회논문지C
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• 제16C권4호
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• pp.535-542
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• 2009

무선센서네트워크는, 다수의 센서노드가 넓은 지역에 배치되어 자신의 전원에 의해 동작하고 다른 센서노드와 협력하여 환경검침 또는 물리량 검침을 수행하는 무선네트워크로 정의한다. 각각의 센서노드들은 자신의 배터리전원소모를 최소화하여, 장기간 사용할 수 있어야 하며, 센서 노드를 적절하게 배치하여 전체 네트워크 커버리지를 제공할 수 있어야 무선센서네트워크의 수명을 늘일 수 있다. 초기 센서노드의 배치로는 센서들의 배터리 수명 등의 이유로 제약이 있으며, 모바일센서노드는 센서가 이동하여 새로운 커버리지를 제공함으로써, 이러한 제약조건을 완화할 수 있다. 본 논문에서는 perimeter coverage property를 만족하는 모바일 센서들의 단계적인 이동을 통한 커버리지 제공기법을 제안한다. 각각의 모바일 센서노드들은 이웃한 센서노드들이 dead 노드인지 판단하게 되며, dead 노드인 경우, 센서네트워크의 커버리지 hole을 만드는지 여부를 판단한 후, 각각의 모바일 센서노드들은 hole의 중심점을 계산하고, 관련된 센서노드들이 협동하여, 단계적으로이동하여, 최종 hole을 커버하는 새로운 센서네트워크를 형성하게 된다. 본 제안기법을 시뮬레이션하여 DCM 기법과 비교한 결과, 에너지 효율을 결정하는 전체 움직임거리 측면에서 최소 50% 이상의 성능향상을 보임을 확인하였다.

• Nutrition Research and Practice
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• 제2권3호
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• pp.184-190
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• 2008

The purpose of this study was to compare the dietary habits, nutrient intake, bone mineral density(BMD) and bone metabolism in Korean male collegians as related to smoking situation. One hundred sixty one young adult males at the age of 20-26 participated in this study. The subjects were divided into four groups: non smoker(n=42), light smoker(n=34), moderate smoker(n=49) and heavy smoker(n=36). The anthropometric characteristics, smoking situations, dietary habits and nutrient intakes were observed. Bone status of the calcaneus was measured by using quantitative ultrasound(QUS). Bone metabolism markers including serum alkaline phosphatase activity(ALP) and N-mid osteocalcin(OC) were analyzed. There were no significant differences in height, weight, BMI, energy and calcium intake among the four groups. Iron intake of moderate and heavy smoker was significantly lower than that of light smoker. Heavy smokers consumed significantly lower vitamin C than moderate smokers, and their coffee consumption and lifetime alcohol consumption were significantly highest among the 4 groups. QUS parameters and serum ALP were not significantly different among the four groups. Serum OC levels were significantly lower in heavy and non smoker group compared to the moderate smoker group. In conclusion, heavy smokers in young male collegians had undesirable lifestyle and dietary habits, like as high consumption of coffee and alcohol, and low intake of Fe and vitamin C. Although, there was no significant difference in their current bone status from the other groups, these undesirable factors with heavy smoking may affect their bone health in the long term.