• 대한임상독성학회지
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• 제4권2호
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• pp.170-174
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• 2006

Methylene blue is a basic thiazine dye frequently used for histologic staining. In clinical toxicology settings, it is also used to treat clinically significant methemoglobinemia. It has dose-dependent oxidation or reduction properties, acting as a reducing agent at lower doses and as an oxidizing agent at higher doses. Hemolytic anemia and hyperbilirubinemia are known toxic effects of methylene blue treatment that have been reported clinically. A 42-year-old woman developed significant methemoglobinemia after acute dapsone overdose; she was treated appropriately with intravenous methylene blue in the therapeutic range. The patient's methemoglobin levels returned to normal. However, 2-4 days later she was noted to have rebound methemoglobinemia, hemolytic anemia, and hyperbilirubinemia. A repeat of Coomb's test and other anemia workups were negative. For management of methylene blue-induced hemolytic anemia, she was administered steroid therapy, N-acetylcysteine, and a blood transfusion. She ultimately recovered, and there were no long-term sequelae from the methylene blue poisoning.

• Journal of Ship and Ocean Technology
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• 제3권1호
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• pp.27-41
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• 1999

The objective of the paper is to study the impact of changing the traditional hull design of bulk carriers by providing them with a double hull while keeping the same deadweight. It is demonstrated that by introducing the double hull the structural reliability is increased throughout the entire life and also the extend of the needed repair is reduced. The results are obtained with recently developed mathematical tools for the reliability assessment of ship hulls subjected to the existence of multiple cracks both in the stiffeners and in the plating and it models the crack growth process. The effect of corrosion is represented as time dependent. The long-term stress range acting on the elements is defined as a function of the local transverse pressure of the internal cargo and outside sea water combined with the stresses resulting from the longitudinal bending of the hull, which is a combined with the stresses resulting from the longitudinal bending of the hull, which is a combineation of horizontal and vertical bending moments. The effect of maintenance actions is modelled as a stochastic process. The results show that a different design of the midship section improves the structural safety and also the economy with respect to structural repair of bulk carriers.

• Bulletin of the Korean Chemical Society
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• 제33권11호
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• pp.3749-3754
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• 2012

Nanoporous carbons with a high specific surface area were prepared directly from thermoplastic acrylic resin as carbon precursor and MgO powder as template by carbonization over the temperature range, $500-1000^{\circ}C$. The effect of the carbonization temperature on the pore structure and $CO_2$ adsorption capacity of the obtained porous carbon was examined. The textural properties and morphology of the porous carbon materials were analyzed by $N_2/-196^{\circ}C$ and $CO_2/0^{\circ}C$ adsorption/desorption isotherms, SEM and TEM. The $CO_2$ adsorption capacity of the prepared porous carbon was measured at $25^{\circ}C$ and 1 bar and 30 bar. The specific surface area increased from 237 to $1251m^2/g$, and the total pore volumes increased from 0.242 to $0.763cm^3/g$ with increasing the carbonization temperature. The carbonization temperature acts mainly by generating large narrow micropores and mesopores with an average pore size dependent on the level of carbonization of the MgO-templated nanoporous carbons. The results showed that the MgO-templated nanoporous carbons at $900^{\circ}C$ exhibited the best $CO_2$ adsorption value of 194 mg/g at 1 bar.

• 한국수소및신에너지학회논문집
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• 제27권1호
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• pp.42-48
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• 2016

This study presents an experiment investigation on natural convection heat transfer of air-cooling Proton exchange membrane fuel cells (PEMFCs) in a enclosure system for unmanned aerial vehicles (UAVs). Considered are replacing fuel cell stack with Aluminum block for heat generating inside a enclosure chamber. The volume ratio of fuel cell stack and chamber for simulation to the actual size of aerial vehicle is 1 to 15. The parameters considered for experimental study are the environmental temperature range from $25^{\circ}C$ to $-60^{\circ}C$ and the block heat input of 10 W, 20 W and 30 W. Effect of the thermal conductivity of the block and power level on heat transfer in the chamber are investigated. Experimental results illustrate the temperature rise at various locations inside the chamber as dependent upon heat input of fuel cell stack and environmental temperature. From the results, dimensionless correlation in natural convection was proposed with Nusselt number and Rayleigh number for designing air-cooling PEMFC powered high altitude long endurance (HALE) UAV.

• Journal of the Korean Wood Science and Technology
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• 제31권3호
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• pp.35-41
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• 2003

The mechanical and physical properties of wood are strongly dependent upon the slope of grain. Specially, tensile strength is more severely affected by the slope of grain. Therefore, tension tests were performed on small thin wood samples made from Pinus radiata with varying the slope of grain. Determining the tensile strength for clear thin wood samples the other variabilities associated with material, size, drying, defects, etc were discarded. Slope of grain was measured by the slope of grain indicator and actual slope of grain was also determined by a protractor. Correlation coefficients between machine measured and actual slope of grain for 40 pieces of 2×20 mm, 300 mm long Pinus radiata were 0.84 for wide face measurement. Results also showed that tensile strength and MOE from stress wave tests decreased with increasing the slope of grain. This study did not establish a relationships for tensile strength and MOE from stress wave with slope of grain. However, the trends of MOEs from stress wave test with both slope of grain are agreed well with Hankinson's equation. Predicted tension strength curve by Hankinson's equation was also agreed well with the experimental data over the range from 0 to 13 degrees for slope of grain.

• Geomechanics and Engineering
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• 제30권5호
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• pp.449-460
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• 2022

Safe underground construction in a rock mass requires adequate ground investigation and effective determination of rock conditions. The estimation of rock mass behavior is difficult, because rock masses are innately anisotropic and heterogeneous at different scales and are affected by various environmental factors. Quantitative rock mass classification systems, such as the Q-system and rock mass rating, are widely used for characterization and engineering design. The measurement of rock classification parameters is subjective and can vary among observers, resulting in questionable accuracy. Geophysical investigation methods, such as seismic surveys, have also been used for ground characterization. Torsional shear wave propagation characteristics in cylindrical rods are equal to that in an infinite media. A probabilistic quantitative relationship between the Q-value and shear wave velocity is thus investigated considering long-wavelength wave propagation in equivalent continuum jointed rock masses. Individual Q-system parameters are correlated with stress-dependent shear wave velocities in jointed rocks using experimental and numerical methods. The relationship between the Q-value and the shear wave velocity is normalized using a defined reference condition. This relationship is further improved using probabilistic analysis to remove unrealistic data and to suggest a range of Q-values for a given wave velocity. The proposed probabilistic Q-value estimation is then compared with field measurements and cross-hole seismic test data to verify its applicability.

• BMB Reports
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• 제56권3호
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• pp.140-144
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• 2023

While CD8⁺ cytotoxic T cells have long been considered the primary effector in controlling tumors, the involvement of CD4⁺ "helper" T cells in anti-tumor immunity has been underappreciated. The investigations of intra-tumoral T cells, fueled by the recent advances in genomic technologies, have led to a rethinking of the indirect role of CD4⁺ T cells that have traditionally been described as a "helper". Accumulating evidence from preclinical and clinical studies indicates that CD4⁺ T cells can acquire intrinsic cytotoxic properties and directly kill various types of tumor cells in a major histocompatibility complex class II (MHC-II)-dependent manner, as opposed to the indirect "helper" function, thus underscoring a potentially critical contribution of CD4⁺ cytotoxic T cells to immune responses against a wide range of tumor types. Here, we discuss the biological properties of anti-tumor CD4⁺ T cells with cytotoxic capability and highlight the emerging observations suggesting their more significant role in anti-tumor immunity than previously appreciated.

• Composites Research
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• 제22권3호
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• pp.9-17
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• 2009

본 논문에서는 분자동력학 방법을 이용하여 Ag 필름/Cu기판에 대한 나노인덴테이션 특성을 파악하였다. 필름의 강성과 경도는 필름의 두께에 관계되어있으며, 임계범위 내에서, 그래인 크기가 증기하면 강성과 경도도 증가하는 것을 확인하였다. 5nm 두께 이하의 Ag필름/Cu기판의 강성과 경도는 벌크 Ag의 경우에 비해 낮은 값을 나타내었다. 특히 4nm 두께 이하의 Ag필름/Cu기판의 인덴테이션에 있어서, 전위 집적과 불일치 전위사이의 상호작용에 의해 계면상에서 꽃모양의 전위 루프가 발생 하였다. 이는 인덴테이션 하중과 변위 커브에서 하중이 저하되는 것과 관계있는 것으로 사료되고 있다.

• 한국농공학회논문집
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• 제65권6호
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• pp.51-63
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• 2023

To improve the problem that the settlement curve of the consolidation theory of Terzaghi does not match well with the actual settlement curve, we included a secondary compression settlement and analyzed it by varying the beginning point and then obtained the following results. The current methods of calculating the compression index from the  log𝜎 curve and the coefficient of consolidation from the time-dependent settlement curve for each consolidation pressure proved that the final settlement amount will be consistent after a long time, but the actual settlement amount will always be smaller than the predicted settlement amount during the settlement progress stage. The consolidation factors estimated by the curve fitting with the condition that the secondary compression begins in the second half of the primary compression showed similar values to the consolidation factors estimated by the curve fitting for the primary compression only, and the settlement curves were in better agreement throughout the compression. It showed different values, showing low validity. It can be inferred that secondary compression acts from the point when a significant portion of the excess pore water pressure is dissipated, and the loading stress begins to have more influence on the skeletal structure of the soil. Analysis results show that secondary compression begins at the range of 91 % to 98 % on the average degree of primary consolidation.

• 한국환경생태학회지
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• 제28권6호
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• pp.642-649
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• 2014

청둥오리는 대표적인 한국내 월동 수조류로 넓은 농경지를 월동지로 이용한다. 한국의 중부지역에 위치한 만경강 하류지역에서 청둥오리 월동 행동권 및 월동지에서 이동거리를 파악하고자 하였다. 2011-2013년 월동기에 Cannon-net을 이용하여 포획된 청둥오리 7개체에 GPS-이동통신 시스템을 기반으로 하는 야생동물위치추적장치(WT-200)를 부착하였다. 청둥오리 행동권 분석은 GIS용 SHP 파일과 ArcGIS 9.0 Animal Movement Extension을 이용하였으며, 커널밀도측정법(Kernel Density Estimation : KDE)과 최소볼록다각형법(Minimum Convex Polygon Method : MCP)을 이용하여 분석하였다. 청둥오리 행동권은 최소볼록다각형법(MCP)에 의해서 $118.8km^2$(SD=70.1, n=7) 이었으며, 커널밀도측정법(KDE)으로는 $60.0km^2$(KDE 90%), $23.0km^2$(KDE 70%) and $11.6km^2$(KDE 50%)이었다. 야생동물위치추적장치(WT-200) 부착지점으로부터 이동거리는 평균 19.4km이었으며, 최대이동거리는 33.2km, 최소이동거리는 9.4km이었다. GPS좌표가 획득된 정점간 거리는 평균 0.8km이었으며, 정점간 이동거리는 최소 6.5km에서 최대 19.7km이었다. 청둥오리는 월동기 동안 매우 짧은 거리를 이동하였으며, 월동지에서 수계 의존성이 매우 높은 경향을 보였다.