• Korean Journal of Clinical Pharmacy
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• v.10 no.3
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• pp.107-110
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• 2000

Theophylline and $\beta$-adrenergic agonists are frequently used together in patients with respiratory diseases. However the clinical impact of $\beta_2$-adrenergic agonists on the blood concentration of theophylline is not fully evaluated. Formoterol, a newly available oral ${\beta}_2$-adrenergic agonist is frequently used in pediatric respiratory patients. The objective of this study was to investigate the effect of oral formoterol on theophylline's blood concentration. Randomized prospective study was conducted. Twenty-four children were enrolled on the study. Their age ranged 2 to 73 months (mean 35.8 months). Theophylline group (12 patients) received 10 mg/kg/day of for theophylline orally. Theophylline/formoterol group (12 patients) received 10 mg/kg/day of theophylline and $4\;{\mu}g/kg/day$ of formoterol orally. All medications were administered at least for 5 days starting on admission day. Theophylline's trough concentrations were obtained on days 3 and day 5. Pulse rates were recorded before the study medications were given on admission, and days 3 and day 5. Statistical significance was calculated by two-tailed Student's t-test. Theophylline's levels in children given theophylline and formoterol together were lower an those given theophylline alone ($6.38\pm0.90\;{\mu}g/ml\;vs\;7.43\pm0.77\;{\mu}g/ml$ on day 3(p<0.05), $5.62\pm0.56\;{\mu}g/ml\;vs.\;6.78\pm0.61\;{\mu}g/ml$ on day 5 (p<0.05)). In both groups, theophylline's trough concentration on day 5 were lower than day 3. There was no significant side effects in both groups. In conclusion, the new ${\beta}_2$ selective adrenergic agonist formoterol reduced serum theophylline levels in children with respiratory diseases. Further investigation is needed to clarify the long term effect of this drug interaction.

• Journal of Periodontal and Implant Science
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• v.26 no.1
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• pp.276-292
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• 1996

The purpose of this study was to evaluate whether removal of gingival epithelium with pulsed Nd :YAG laser could inhibit the downgrowth of junctional epithelium after alloplastic material grafting in periodontal bone defect. The periodontal bone defects were created surgically on the palatal aspect of the upper right and left molar teeth in 30 rats and filled with resorbable calcium carbonate($Biocoral\;450^{(R)}$: Inoteb, France). The control sites(right molar area) was sutured. The test side (left molar area) received controlled deepithelization of the oral and sulcular epithelium with pulsed Nd:YAG laser($Sunrise\;Maste^{(R)}$: Sunrise Technologies, U.S.A.) under the mode of 1.75W, 15Hz, 116mJ/pulse and was sutured. The control and test sites were evaluated clinically and histologically, at 1, 3, 7, 14, and 28 days postoperation. Clinically, the gingiva showed normal color and shape at the 5th day in the control site and at the 10th day in the test sites. Histologically, the junctional epithelium was formed at the 7th day in the control sites and at the 14th day in the test sites, and the long JE attachment were observed at the 28th day in both sites. The attachment of connective tissue to root surface was observed initially at the 7th day in the control sites and at the 14th day in the test sites, and completed at the 28th day in both sites. In summary, these results showed that the removal of oral epithelium using pulsed Nd:YAG Laser could not prevent epithelial downgrowth after alloplastic material implantation in rat periodontal bone defect.

• Journal of Korean Medical classics
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• v.29 no.3
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• pp.113-132
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• 2016

Objectives : In this study, the Abdominal Diagnostic Method of Kitao Shunpo(北尾春圃) about Movement Qi between kidneys in Sanghauidam(桑韓醫談) and Jeonggisinron(精氣神論) are investigated for the purpose of understanding the definite technique of the method and the position in the context of abdominal diagnosis in Japan. Methods : The materials related to the abdominal diagnosis to Movement Qi between kidneys were selected from Sanghauidam and Jeonggisinron written by Kitao Shunpo, and analyzed to know the characteristics of the method. Results : Kitao Shunpo suggested the theoretical background of the Abdominal Diagnostic Method that Original Qi(元氣) is made from Original Essence(元精) when a person is born, and mentality(神) and body essence(精), qi(氣) and blood(血) are formed from those. Movement Qi between kidneys(腎間動氣), that is to say innate Original Qi can be diagnosed in abdominal region by the method in Japanese Medicine. Kitao Shunpo decided deficiency and excess of Original Qi and prognosis in clinical treatment by the method, and suggested the standard pulse condition of the Movement Qi between kidneys. Conclusions : After the theory about Movement Qi between kidneys appeared in Nanjing(難經), many doctors have not made attention to diagnose that for a long time, until Kitao Shunpo with other Japanese doctors established the theoretical background of the Abdominal Diagnostic Method, and applied the theory to clinical treatment.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2007.10a
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• pp.901-904
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• 2007

Nowadays, in many fields of medical treatment, we can make an observation and a diagnosis of inward disease without using a surgical operation. As one of them, ultra-sound diagnosis system can be available widely in its cost and size compared with other medical instruments. This system also make it possible for us to see the inner parts of the body in real time harmlessly for a long time. So it can be utilized to inspect the movement of heart or fetus and to diagnose an internal disease of the soft tissues. Ultra-sound images can be generated by the reflexive and scattered wave through the pulse generator and so in ultrasound images there exist inherently many affective noised signals. In this paper, we are to take an noise-restrained image and to extract a more affective regions of the images.

• Journal of Biomedical Engineering Research
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• v.29 no.5
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• pp.371-375
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• 2008

In blood pressure measurement, the oscillometric method detects and analyzes the pulse pressure oscillation while deflating the cuff around the arm. For its principle, one has to inflate cuff pressure above the subject's systolic pressure and deflate below the diastolic pressure. Most of the commercialized devices inflate until the fixed target pressure and deflate until the fixed completion pressure because there is no way to know the systolic and diastolic pressure before measurement. Too high target pressure makes stress to the subject and too low target pressure makes big error or long measurement time because of re-inflation. There are similar problems for inadequate completion pressure. In this study, we suggest new algorithm to set proper target and completion pressure for each subject by analyzing pressure waveform while inflating period. We compared our proposed method and auscultation method to see the errors of estimation. The differences between the two measurements were -4.02$\pm$4.80mmHg, -10.50$\pm$10.57mmHg and -0.78$\pm$5.l7mmHg for mean arterial pressure, systolic pressure and diastolic pressure respectively. Consequently, we could set the target pressure by 30 mmHg higher than our estimation and we could stop at 20mmHg lower than our estimated diastolic pressure. Using this method, we could reduce the measurement time.

• Journal of radiological science and technology
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• v.18 no.2
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• pp.61-73
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• 1995

For the managements of the diagnostic X-ray equipments, the authors examined the output of single phase rectification assembly, Three phase rectification assembly and serial radiographic appartus, and got the following conclusions. 1. When the tube voltages in X-ray control panels ware compared to the measured values on the kVp pulse meter, only little differences were detected in all the X-ray equipments. And most of the equipments were all well managed within the internationally permitted limits, excepting the 12.02 % error at 120 kVp in three phase rectifying assembly. 2. As for the X-ray qualities affecting the X-ray images, the serial radiographic apparatus showed excellence, while the single phase rectification assembly were somewhat inferior to the others only maining the internationally recommended limits. 3. The tube voltage ranges where the X-ray output showed excellence were $100{\sim}200\;mA$ in serial radiographic apparatus, $200{\sim}350\;mA$ in three phase rectification assembly and $350{\sim}400\;mA$ in single phase rectification assembly respectively. 4. In the repeatability test of the X-ray equipments, CVs were in the range of $0.0029{\sim}0.049$, which is within the HEW or KS standards. Consequently all the equipments are thought to be well-manage. 5. This study on characteristics and output of the X-ray equipments was accomplished within a limited short time. Long-time researches on the function managements for the X-ray equipments should be followed along with the periodical checking the output for reduction of X-ray exposures to the patients or radio-technologists, and for maintanance and prediction of trouble of the equipments.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.4
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• pp.2639-2646
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• 2015

This study was to identify the effects of supportive nursing intervention using video-program of operating room nurses before operation on laparoscopic hysterectomy patient's anxiety. This study was nonequivalent control group pre-post test design. The data were collected from May 1 to Jun 20, 2013 and analyzed by $x^2-test$, Fisher's exact test and t-test using SPSS 20.0 program. Experimental group(who received supportive nursing intervention) and control group(who received booklet education) was respectively consisted of 25 patients who were laparoscopy hysterectomy. The anxiety(p=.002) of experimental group was significantly lower than control group. The systolic(p=.012) and diastolic(p=.045) pressure of experimental group was significantly lower than control group, but pulse wasn't. The supportive nursing intervention for preoperative patient is considered effective and useful in reducing anxiety. Further research is warranted to investigate the supportive nursing intervention long-term effect.

• Korean Journal of Optics and Photonics
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• v.17 no.3
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• pp.290-295
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• 2006

The coupling between copper wire and a THz electromagnetic wave is one of the important factors to build up the magnitude and spectrum of a THz wave. We measured a I THz spectrum range THz pulse into a $480{\mu}m$ diameter and 23cm long copper wire waveguide. We measured THz pulses up to $275{\mu}m$ air gap between the end of the copper wire and transmitter or receiver chips. The coupling sensitivity of the transmitter is 3 times bigger than that of the receiver. The THz pulses propagated to air by the end of the receiver-side copper wire tip acting as a transmitter antenna. We confirmed that the THz field concentrates near the copper wire surface by opening the pin hole to the copper wire waveguide.

• Journal of the korean academy of Pediatric Dentistry
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• v.29 no.3
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• pp.455-462
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• 2002

Currently, the ages of the patients visiting dental hospital for dental care are becoming younger and the interest in the treatment for the handicapped and incapable of cooperation children increases. As a method for treatment of these patients, the sedation treatment is considered. A dental sedation using chloral hydrate and hydroxyzine of them were used widely and for a long time. In this study, the samples were consisted of incapable of cooperation or very young children required treatment of restoration under local anesthesia. Then, the vital signs were accessed in pediatric dental sedation using the combination of chloral hydrate and hydroxyzine. As a result of this study, the vital signs were little different in pediatric dental sedation using the combination of chloral hydrate and hydroxyzine. Simply, the respiration rate and pulse rate decreased according to sleeping of patients. Therefore, the sedation using the combination of chloral hydrate and hydroxyzine induced to appropriate sedation in incapable of cooperation or very young children with little effects of vital signs.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.61 no.12
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• pp.1892-1897
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• 2012

Modern electronic circuits are of importance for the function of communication, traffic systems and security systems. An intentional threat to these systems could be of big casualties and economic disasters. This study has examined susceptibility of electronic circuits inside the cavity by HPEM(High Power Electromagnetics). The UWB measurements were done at an anechoic chamber using a RADAN voltage source, which can generate a transient impulse of about 200 kV. The HPEM wave penetrated inside the metal case appeared to the long damped ringwave of pulse length compared with the incident wave. In addition, the resonant frequency generated inside the metal case occurred primarily in the range of 1~3 GHz. The frequency band of 1~3 GHz was influenced on the electronic circuit, which was confirmed by an external antenna and an internal absorber. The electronic circuit was influenced by HPEM infiltrated into the cavity at the 86 kV/m out of the metal cases. Also in case of an absorber the susceptibility of an electronic circuit was smallest among other cases(aperture, antenna). It is considered that absorber has a function absorbing electromagnetic wave infiltrated into the cavity and simultaneously limiting resonance by varying a boundary condition inside the cavity. Based on the results, electronic equipment systems could be applied to protection that has suited system requirements.