• Title/Summary/Keyword: Local tissue

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The Clinical Manifestations of Lipoblastoma in Children (소아 Lipoblastoma의 임상 양상)

  • Nam, So-Hyun;Kim, Dae-Yeon;Kim, Seong-Chul;Kim, In-Koo
    • Advances in pediatric surgery
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    • v.13 no.2
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    • pp.179-186
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    • 2007
  • Lipoblastoma is a rare benign soft tissue tumor occurring in infancy and early childhood. It is characterized by fat lobules with varying degrees of maturity, multivaculoated lipoblasts, fibrocapillary networks and myxoid stroma. Lipoblastoma has a good prognosis with no metastases despite its potential for local invasion. From Jan, 1990 through April, 2007, 12 children underwent the operation for lipoblastoma, 7 boys and 5 girls, diagnosed at median 22 months (5 ~ 43 months). Median follow up was 6 year 7 months. Primary sites included back (n = 5), intraabdominal (n = 2) and one in each of buttock, chest wall, neck, nose and scalp. Tumors presented with a growing mass in 9 patients, abdominal distension in 2, and an incidental finding on chest radiography in one. Complete excisions were done in all patients. There was one recurrence in a patient with a scalp mass. After reoperation, he has been doing well without evidence of recurrence. Lipoblastoma has a favorable prognosis, but recurrence can occur even with complete excision. Regular follow up is necessary to detect recurrences.

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Leiomyosarcoma of the Face

  • Ko, Young-Il;Lim, Jin-Soo;Han, Ki-Taik;Kim, Min-Cheol
    • Archives of Craniofacial Surgery
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    • v.15 no.1
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    • pp.36-39
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    • 2014
  • Leiomyosarcoma is a rare form of soft tissue neoplasm, with only 1% to 5% occurring in the head and neck region. Current recommended treatment suggests surgical excision with a wide lateral margin, but no definite guidelines regarding excisional margin have been established yet. Recently, complete excision with a narrow surgical margin has been recommended, and the authors present a case of cutaneous leiomyosarcoma on the face that was successfully managed by complete removal with a narrow excisional margin. A 74-year-old woman presented with a 3 cm sized, rapidly growing cutaneous mass on her right preauricular area. Preoperative biopsy of the skin lesion suggested a cutaneous leiomyosarcoma. The authors performed complete surgical excision with a 1 cm lateral margin, and the resulting skin defect was repaired with bilateral V-Y advancement local flaps. Histopathology and immunohistochemistry evaluation confirmed a moderately differentiated cutaneous leiomyosarcoma, with negative margin involvement. The patient refused of any additional treatment, but showed no locoregional recurrence during the 1.5 years of postoperative follow-up period. With a regular postoperative follow-up, cutaneous leiomyosarcomas may be successfully treated with a narrow surgical margin.

Two Cases of Acute Lung Injury Caused by Nitrogen Dioxide Inhalation (이산화질소($NO_2$)에 의한 폐손상 치험 2예)

  • Kim, Yeon-Jae;Kim, Seong-Ho;Kim, Su-Dong;Cha, Seung-Ick;Lee, Yeung-Suk;Park, Jae-Yong;Jung, Tae-Hoon
    • Tuberculosis and Respiratory Diseases
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    • v.40 no.4
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    • pp.436-441
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    • 1993
  • Human lung injury caused by the inhalation of nitrogen dioxide($NO_2$) has been reported in occupational situations other than agriculture, including arc welding, production of nitric acid or explosives, and blasting operations. Nitrogen dioxide reacts with the water in the respiratory tract to form nitric acid. The nitrates and nitrites formed from dissociation of nitric acid cause extensive local and systemic tissue damage. We present two cases of acute lung injury due to accidental inhalation of $NO_2$ gas in occupational situtions with a review of the literature.

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Myopericarditis by an Ingestion of Hydrofluoric acid - A case report (불화수소 음독 후 발생한 심금염 1례)

  • Kim Sun Hyu;Kim Hyun;Ji Ho Jin;Jang Yong Soo;Oh Sung Bum;Lee Kang Hyun;Hwang Sung Oh
    • Journal of The Korean Society of Clinical Toxicology
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    • v.2 no.1
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    • pp.63-66
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    • 2004
  • Hydrofluoric acid (HF), one of the strongest inorganic acids, is used mainly for industrial purpose. Hydrofluoric acid injuries has a potential for both systemic as well as severe local tissue destruction. One of the most serious consequences of severe exposure to HF by any route is marked lowering of serum calcium (hypocalcemia) and other metabolic changes, such as hypomagnesemia and which may result in a fatal outcome if not recognized and treated. promptly cardiotoxicity is not well known except arrhythmias, which are a primary cause of death. We report a case of myopericarditis by ingestion of hydrofluoric acid.

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CASE REPORT : THE CONSERVATIVE TREATMENT OF UNILOCULAR PLEXIFORM AMELOBLASTOMA (보존적 치료를 통한 단방성 총상형 법랑모세포종의 치험례 : 증례보고)

  • Choi, Su-Jin;Chee, Young-Deok;Koh, Se-Wook;Kim, Hyong-Woo;Choi, Ji-Yeun;Lee, Jae-Hwan
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.34 no.4
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    • pp.498-502
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    • 2008
  • Ameloblastoma is the most common aggressive benign odontogenic tumor of the jaws. Because of slow growth and tendency to local invasion of bone and soft tissue, high rates of recurrence are common. The treatment for ameloblastoma is still controversial and poses some special problems in children. Because of growth of the jaw and the different incidence, prognosis of the tumor make the surgical consideration different from adults. Radical resection cause facial deformity, jaw abnormal movement and masticatory disturbance especially to child and adolescents. So conservative treatment as enucleation, curettage is acceptable initial treatment of ameloblastoma in children who can be followed up in a precise, detailed manner. This report describes a case of unilocular plexiform ameloblastoma treated by enucleation and curettage followed by marsupialization.

The Applications of the Duplex Stainless Steel as Hyperthermia Materials

  • Kim, Young-Kon
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2009.05a
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    • pp.7.1-7.1
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    • 2009
  • The use of Duplex stainless steel as a thermo-implant categorizes into two clinical applications: hyperthermia and thermal ablation or destruction. The goal of hyperthermia is to destroy the heat-sensitive abnormal cells and minimize normal cell death maintaining heat between $42^{\circ}C$ and $46^{\circ}C$. Thermal ablation takes place when the local tissue temperature increases greater than $46^{\circ}C$. This elevated temperature denatures protein irreversibly resulting cellular death. The author introduced several thermo-implants such as thermo-rod, thermo-stent, thermo-coil and thermoacupuncture-needle. Those thermo-implants are made of duplex stainless steel which can produce regulated heat by itself within an induction magnetic field. Thermal ablation characteristics of the thermo-rod on tumor hyperthermia depend on configurations of the thermo-rods and the magnitude of the induction magnetic strength. The exothermic properties of the thermo-implants can be characterized using the calorimetric test and the heat affected zone(HAZ) analyses in vitro. Thermal radiation studies using thermo-coils and thermo-stents show the capability of the occlusion of animal blood vessels and inhibiting the proliferation of the abnormal smooth muscle cell growth and inflammatory cell reactions maintaining the heat between $42^{\circ}C$ and $46^{\circ}C$ minimizing a normal cell death in the study on external iliac artery of the New Zealand White (NZW) rabbit. Thermal stimulation study using thermo-acupuncture needles suggests the potential applications of the automated acupunctural therapies.

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Chondrosarcoma of Proximal Tibia Trated by Allograft - A Case Report - (동종골 이식술로 치료한 경골 근위부에 발생한 연골 육종 - 증례 보고 -)

  • Jung, Gu-Hee;Kim, Jae-Do;Chung, So-Hak;Cha, Sang-Won
    • The Journal of the Korean bone and joint tumor society
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    • v.12 no.2
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    • pp.165-170
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    • 2006
  • We reported a case of chondrosarcoma in proximal tibia in a 44-year-old man. MR images demonstrated a $3.5{\times}20$ cm sized bone tumor. In reconstruction of resected proximal tibia, we used the allograft bone and soft tissue defects were covered by medial gastrocnemius rotation flap and skin graft. There were no local recurrence and distant metastasis and any complication such as secondary infection, nonunion, metal failure at the time of the last follow-up. There was no limitation of knee motion through the appropriate rehabilitaion programs.

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Clinical effectiveness of combining platelet rich fibrin with alloplastic bone substitute for the management of combined endodontic periodontal lesion

  • Goyal, Lata
    • Restorative Dentistry and Endodontics
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    • v.39 no.1
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    • pp.51-55
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    • 2014
  • The term "endo-perio" lesion has been proposed to describe the destructive lesion resulting from inflammatory products found in varying degrees in both the periodontium and the pulpal tissues. In most of the cases, clinical symptoms disappear following successful endodontic therapy. However failure after conventional root canal treatment calls for surgical intervention. A 35 year old male patient with endo-perio lesion in right maxillary lateral incisor was treated with platelet rich fibrin (PRF) and alloplastic bone substitute after conventional endodontic therapy. At the end of 6 months there was gain in clinical attachment, increased radiographic bone fill and reduction in probing depth which was maintained till 18 month follow-up. Present case report aims to evaluate the efficacy of PRF and alloplastic bone substitute in the management of intrabony defect associated with endo-perio lesion in maxillary lateral incisor because the healing potential of PRF and bone graft has not been widely studied in endodontics. The use of PRF allows the clinician to optimize tissue remodelling, wound healing and angiogenesis by the local delivery of growth factors and proteins. The novel technique described here enables the clinician to be benefited from the full regenerative capacity of this autologous biologic material.

Basal Cell Adenocarcinoma of the Parotid Gland (이하선의 기저세포선암)

  • Lee Joon-Ho;Chung Woung-Yoon;Park Cheong-Soo
    • Korean Journal of Head & Neck Oncology
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    • v.13 no.1
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    • pp.81-85
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    • 1997
  • Basal cell adenocarcinoma is a rare, recently described neoplasm of the salivary gland. We have experienced three cases of basal cell adenocarcinoma of the parotid gland. The tumors from patient 1 and patient 2 showed intraparotid growth in superficial lobe without cervical lymphnode metastasis. So, patient 1 and patient 2 underwent only a superficial parotidectomy and subdigastric lymphnode dissection without any adjuvant therapy. They are alive without recurrence or distant metastasis. But that of patient 3 showed widely invasive growth with multiple cervical lymph node metastases. The CT scan showed a $8{\times}7cm$ sized huge mass replacing the parotid gland with irregular margin and multiple lymphnode enlargements along the internal jugular vein. Total parotidectomy with sacrifying the facial nerve and standard radical neck dissection were caried out. Microscopically, the tumor consisted of solid nest and sheet of uniform basaloid cells separated by a fibrous connective tissue stroma with the evidence of lymphovascular invasion. As a result of the lymphnode metastasis and invasiveness of the tumor, radiation therapy was given postoperatively. We thought that close follow-up would be mandatory in this patient because of high risk of possible local recurrence and distant metastasis.

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A Case of Chondroid Choristoma on the Dorsum of the Tongue (설배부에 발생한 연골성분리종 1례)

  • Kil, Bu Kwan;Son, Ho Jin;Kim, Bo Mun;Joung, Jae Won;Kim, Jeong Kyu
    • Korean Journal of Head & Neck Oncology
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    • v.34 no.2
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    • pp.43-46
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    • 2018
  • Chondroid choristomais a rare tumor like lesion of normal tissue in an unusual location. Oral cavity chondroid choristoma is exceedingly uncommon. This lesion is commonly covered by normal oral mucosa and can develop during a whole lifetime. We experienced a case of 57-year-old man who presented as 6-months history of asymptomatic mass on the dorsal surface of the tongue. We performed surgical excision under local anesthesia, and the pathological diagnosis was chondroid choristoma. After surgery, patient was followed up without any recurrence and discomfort. Therefore, we report this case with a review of literature.