• 지질공학
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• 제22권2호
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• pp.173-183
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• 2012

본 연구에서는 응력완화실험을 통한 포화상태에서의 토노(Tono) 화강암의 표면변형에 대한 연구를 수행하였다. 본 실험을 위해서 실험이 진행되는 동안 실시간으로 다초첨 레이져 스캔 현미경(Confocal Laser Scanning Microscope, CLSM)으로 관찰이 가능하고 변위 및 응력에 대한 데이터 취득이 가능한 장치를 고안하였다. 광물내의 변형 및 광물경계부에서의 변형은 유한요소해석 방법을 사용하여 계산하였다. 그 결과 응력완화실험 중에는 광물 내부와 광물 경계부 모두에서 활발한 변형을 보이는 것이 관찰되었으며 이는 가해지는 응력이 높아질수록 더욱 커진다는 사실을 확인하였다. 또한 유한요소 해석의 결과는 광물내의 변화보다는 압축력에 의해서 발생되는 광물경계부에서의 변화가 더욱 크다는 것을 설명한다. 이를 도식화시켜 표현해보면 화강암 내부에서 광물 경계부의 변형이 광물 내부의 변형보다 크게 나타난다는 것을 쉽게 관찰 할 수 있다. 이는 흑운모와 석영의 물리화학적 특성에 기인된다고 사료된다. 즉 석영은 안정된 구체를 보이는 반면에 흑운모는 층상형태로 약한 결합구조를 보이고 있기 때문으로 판단된다.

• 대한지역사회영양학회지
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• 제11권1호
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• pp.39-51
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• 2006

This study was conducted to investigate the differences in daily nutrient intakes, dietary habits and nutrition knowledge between male and female college students. Male undergraduate students 004 subjects) and female undergraduate students (229 subjects) , enrolled at H University in Daejeon, were recruited for this study. The mean age of the subjects was 22.9 year in male and 20.4 year in female students. Daily intakes of energy and nutrients were calculated from the records of one day of dietary food intakes by 24-hour recall method, and general information, dietary habits and attitudes, food intake frequency and food preferences and knowledge for food and nutrition were surveyed through a questionnaire. About $70.1\%$ of male and $66.1\%$ of female students were in the normal range of BMI (18.5 - 23), and $25.2\%$ of male students were over-weighted in contrast to $27.7\%$ of female students were underweight. Males and females were taking $77.2\%$ and $77.9\%$ of RDA for energy, respectively, and $54.8\%$ of male and $48.0\%$ of female students were taking energy under $75\%$ of RDA. Many of them showed deficient intakes of calcium, iron, vitamin A and riboflavin. Average of MAR was 0.75 in male and 0.72 in female students. NAR for calcium, iron, vitamin A and riboflavin in male students were 0.55, 0.69,0.75 and 0.61, respectively, compared to 0.53, 0.51, 0.70 and 0.67 in female students. The nutrients, which have INQ less than 1, were calcium and riboflavin in male, compared to calcium, iron, and riboflavin in female students. There were no gender differences in meal regularity and meal skipping rates, but female students showed higher rates of skipping dinner than males (p < 0.001) About $50.8\%$ of female students were ingesting snacks 1 - 2 time/day, compared to $27.1\%$ of male students. For the food intake frequency, fruit group was significantly eating more for female than male students (p< 0.001) Though female students got higher scores for nutritional knowledge test (p < 0.001) than male students, they did not show better dietary habits or dietary attitudes than male students actually. Therefore, a more active and actual education program accustomed to the different genders and ages with focus on real changing of dietary behaviors needs to be developed and run in schools and local departments.

• 대한교통학회지
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• 제32권4호
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• pp.303-314
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• 2014

본 연구는 우리나라 도로 교통부분의 이산화탄소 배출량 관리를 위한 지역별 배출량 산정 방법에 대한 연구로서 지역별로 서로 다른 통행패턴(기종점 통행, 통과 통행)을 고려하였다. 기초자료는 국가교통DB센터(KTDB)에서 제공하는 O/D 및 Network 자료를 이용하였다. 분석 결과, 기존 연구에서 제공하는 수도권의 총 이산화탄소 배출량은 매우 유사한 수준으로 분석되었다. 경기도를 중심으로 권역을 설정하여 분석한 결과, 경기도 남부 지역에서는 통과교통량에 의한 이산화탄소 배출량이 지역 배출량에 비해 높게 나타났으며, 북부 지역에서는 지역 배출량의 비율이 높은 것으로 나타났다. 이러한 결과는 통행의 구분에 따라 지자체에서 관리할 수 있는 배출량과 국가 차원에서 관리할 수 있는 배출량을 구분할 필요가 있을 것으로 판단된다.

• 한국수자원학회논문집
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• 제43권12호
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• pp.1083-1091
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• 2010

분포형 수문 모형의 일강우 입력 자료는 불가피하게 불규칙하고 밀도가 낮은 관측망에서 기록된 값을 내삽해 사용하게 되나, 흔히 사용되는 대부분의 내삽법들은 실제 일강우의 다양한 공간적 분포를 잘 재현하지 못하는 문제가 있다. 본 연구에서는 널리 사용되는 다섯 가지의 강우 내삽 방법을 두개의 유역에 사용하여 비교하고 실제 공간적 분포를 보다 잘 나타낼 수 있는 2단계 내삽법을 제안하였다. 비교에 사용된 내삽법은 (1) 역가중치 방법(IDW), (2) 다중회귀분석 (MLR), (3) 월강우를 이용한 다중회귀분석법(CMLR), (4) 국지가중치 다중회귀분석(LWP) 등이다. 보다 향상된 내삽을 위한 2단계 내삽법은 먼저 로지스틱 회귀분석으로 강우-비강우 지역을 구분하고 강우 지역에서만 기존의 내삽법을 적용하여 강우량을 구하는 방법이다. 기존 방법과의 비교결과 공간적인 편차가 심한 일강우의 특성을 2단계 내삽법에서 잘 표현하고 있는 것으로 나타났다. 제안된 방법은 수문모형에의 적용뿐만 아니라 유출량의 예보 및 대기 순환 모형의 다운 스케일링에도 효과적으로 사용될 수 있을 것으로 기대된다.

• 보존과학회지
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• 제30권2호
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• pp.111-122
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• 2014

서천 봉선리유적은 백제의 중앙과 지방의 묘제가 혼재하고 있는 유적으로 백제 중앙에서 재지세력에세 사여한 것으로 추정되는 환두도가 다량 출토되었다. 이것은 재지세력이 백제 중앙의 관리 하에 놓이는 과정을 나타내는 부장유물로 추정된다. 이 중 4점의 환두도와 1점의 목병도를 대상으로 금속학적 분석을 실시하여 무기로서의 실용적 기능과 부장용 의장용으로써의 비실용적 기능에 대하여 연구하였다. 목병도 1점은 담금질과 고체침탄의 제강기술을 이용하여 제작되었으며 무기로서의 실용성을 가진다고 볼 수 있다. 반면 4점의 환두도는 인부에는 강도가 작은 미세조직이 나타나고 배부에서 충격을 흡수할 만큼의 미세조직이 나타나지 않으므로 목병도에 비해 무기로서의 기능은 떨어진다고 볼 수 있다. 즉, 서천 봉선리에서 출토된 목병도와 환두도는 실용기와 비실용기로 명확히 구분되는 것이 가장 큰 특징이라고 할 수 있다. 또한 미세조직 내에 존재하는 비금속개재물을 분석한 결과 우스타이트와 유리상이 함께 발견되므로 제련 공정에는 저온환원법이 적용되었을 가능성이 크다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권9호
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• pp.3595-3604
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• 2015

Hepatocellular carcinoma (HCC) has been one of the most fatal malignant tumors worldwide and its associated morbidity and mortality remain of significant concern. Based on in-depth reviews of serological diagnosis of HCC, in addition to AFP, there are other biomarkers: Lens culinaris agglutinin-reactive AFP (AFP-L3), descarboxyprothrombin (DCP), tyrosine kinase with Ig and eprdermal growth factor (EGF) homology domains 2 (TIE2)-espressing monocytes (TEMs), glypican-3 (GPC3), Golgi protein 73 (GP73), interleukin-6 (IL-6), and squamous cell carcinoma antigen (SCCA) have been proposed as biomarkers for the early detection of HCC. The diagnosis of HCC is primarily based on noninvasive standard imaging methods, such as ultrasound (US), dynamic multiphasic multidetector-row CT (MDCT) and magnetic resonance imaging (MRI). Some experts advocate gadolinium diethyl-enetriamine pentaacetic acid (Gd-EOB-DTPA) MRI and contrast-enhanced US as the promising imaging madalities of choice. With regard to recent advancements in tissue markers, many cuting-edge technologies using genome-wide DNA microarrays, qRT-PCR, and proteomic and inmunostaining studies have been implemented in an attempt to identify markers for early diagnosis of HCC. Only less than half of HCC patients at initial diagnosis are at an early stage treatable with curative options: local ablation, surgical resection, or liver transplant. Transarterial chemoembolization (TACE) is considered the standard of care with palliation for intermediate stage HCC. Recent innovative procedures using drug-eluting-beads and radioembolization using Yttrium-90 may exhibit beneficial effects in HCC treatment. During the past few years, several molecular targeted agents have been evaluated in clinical trials in advanced HCC. Sorafenib is currently the only approved systemic treatment for HCC. It has been approved for the therapy of asymptomatic HCC patients with well-preserved liver function who are not candidates for potentially curative treatments, such as surgical resection or liver transplantation. In the USA, Europe and particularly Japan, hepatitis C virus (HCV) related HCC accounts for most liver cancer, as compared with Asia-Pacific regions, where hepatitis B virus (HBV) may play a more important role in HCC development. HBV vaccination, while a vaccine is not yet available against HCV, has been recognized as a best primary prevention method for HBV-related HCC, although in patients already infected with HBV or HCV, secondary prevention with antiviral therapy is still a reasonable strategy. In addition to HBV and HCV, attention should be paid to other relevant HCC risk factors, including nonalcoholic fatty liver disease due to obesity and diabetes, heavy alcohol consumption, and prolonged aflatoxin exposure. Interestingly, coffee and vitamin K2 have been proven to provide protective effects against HCC. Regarding tertiary prevention of HCC recurrence after surgical resection, addition of antiviral treatment has proven to be a rational strategy.

• 자원환경지질
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• 제24권4호
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• pp.421-434
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• 1991

경상분지내에서 가장 뚜렷한 선구조로 나타나는 양산 단층이 지나는 곳으로 생각되는 네 지역을 선정하여 육상자력탐사를 실시하였다. 정성적 분석을 위한 자료처리과정으로는 표준자기장 (IGRF) 보정, 상향 연속과 자극화 변환을 수행하였고, 정량적 해석을 위해서는 수평 2층 지하 지질구조에 있어서 하부층까지의 심도를 모델변수로 하는 비선형 자동 역산법을 적용하였다. 육상자력 이상도의 상향 연속 결과와 동일 지역에서 수행된 항공 자력 탐사자료를 비교한 바에 의하면 두 자료의 유사도가 비교적 높게 나타났다. 네 곳의 탐사지역내에서 양산 단층의 주향은 북동$6^{\circ}-15^{\circ}$의 경향이 우세하게 나타났으며, 단층의 경사는 지역적인 암상의 변화에도 불구하고 수직내지 약간 동쪽 방향의 경사를 갖는 것으로 나타났다. 탐사 지역중 가장 북쪽에 위치하는 안강부근의 제 1 탐사지역에서는 단층구조에 의한 자력효과가 화성암의 관입에 의한 효과와 함께 나타난 복잡한 양상을 띠며, 언양부근의 제 2 탐사 지역에서는 단층면을 따라 약 200 - 300 미터의 폭을 갖는 화산성, 혹은 화성 기원의 관입이 일어난 것으로 보인다. 용연 부근의 제 3 지역에서는 다른 지역과는 달리 단층운동에 의한 것으로 생각되는 파쇄대가 약 600 - 700 미터 정도의 폭으로 비교적 뚜렷하게 나타났다. 가장 남쪽에 위치하는 양산부근의 제 4 지역에서는 안산암 시료가 매우 큰 대자율 값을 보이며, 본 연구 결과 이 지역의 단층선은 기존 연구에서 제시된 단층선보다 약 500 미터 정도 동쪽으로 치우쳐 나타난다.

• 한국소음진동공학회논문집
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• 제14권6호
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• pp.528-535
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• 2004

Ultrasonic Vibrator is designed to achieve the maximum vibration amplitude at 30 kHz by in-cluding a horn (diameter, 40 mm), mechanical vibration amplifier at the top of the ultrasonic vibrator in the system and making the complete system resonate. In addition, it is experimentally visualized by particle imaging velocimetry (PIV) that the acoustic streaming velocity in the gap is at maximum when the gap between the ultrasonic vibrator and stationary plate agrees with the multiples of half-wavelength of the ultrasonic wave. This fact results from the resonance of the sound wave and the theoretical analysis of that is also accomplished and verified by experiment. It is observed that the magnitude of the acoustic streaming dependent upon the gap between the ultrasonic vibrator and stationary plate possibly changes due to the measurement of the average velocity fields of the acoustic streaming induced by the ultrasonic vibration at resonance and non-resonance. There exists extremely small average velocity at non-resonant gaps while the relatively large average velocity exists at resonant gaps compared with non-resonant gaps. It also reveals that there should be larger axial turbulent intensity at the hub region of the vibrator and at the edge of it in the resonant gap where the air streaming velocity is maximized and the flow phenomena is conspicuous than that at the other region. Because the variation of the acoustic streaming velocity at resonant gap is more distinctive than that at non-resonant gap, shear stress increases more in the resonant gap and is also maximized at the center region of the vibrator except the local position of center (r〓0). At the non-resonant gap there should be low values of vorticity distribution, but in contrast to the non-resonant gap, high and negative values of it exist at the center region of the vibrator with respect to the radial direction and in the vicinity of the middle region with respect to the axial direction. Acoustic streaming is noise-free due to the ultrasonic vibration and maintenance-free because of the absence of moving parts. Moreover, the proposed method by acoustic streaming can be utilized to the nano and micro-electro mechanical systems as a driving mechanism in addition to the augmentation of the streaming velocity.

• 대한두경부종양학회지
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• 제15권1호
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• pp.35-39
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• 1999

Objectives: The treatment for squamous cell carcinoma of the tonsil remains controversial. Surgery or radiation therapy alone is effective in treating early tonsil cancer, but results with single treatment modality in advanced disease have been disappointing. We retrospectively analyzed 37 patients with advanced squamous cell carcinoma of the tonsil for two treatment modalities in an effort to identify more efficacious therapeutic options. Materials and Methods: From 1990 through 1997, 37 patients who were treated primarily with surgery, were retrospectively sudied. The patients were grouped into two groups according to the method of treatment, extended tonsillectomy followed by irradiation and/or postradiation neck dissection(Group I) and a combination of composite resection and postoperative radiation(Group II). Results: The three year disease-tree survival in patients with stage IV lesions was 59.09% for the Group I patients, and 56.25% for the Group II patients. This difference was not statistically significant(p=0.775). The primary tumor recurrence rate in Group I was 16.7% in contrast to 23.1% for Group II. The local recurrence rate in the neck was 16.7% for the Group I patients and 23.1% for the Group II patients. There was no significant difference in the frequency of recurrences in the primary or neck in the patients treated with extended tonsillectomy or composite resection(p=0.639). Fistula formation and aspiration occurred in four patients after composite resection. Additionally, there were three trismus, one soft tissue necrosis, and one velopharyngeal insufficiency. Major complications were not observed in the patients treated with extended tonsillectomy and irradiation: velopharyngeal insufficiency was observed in eight patients and soft tissue necrosis in two patients. Conclusion: Extended tonsillectomy followed by irradiation may be an effective therapy with low morbidity in selected patients with tonsil cancer.

• Korean Journal of Radiology
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• 제22권9호
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• pp.1525-1536
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• 2021

Objective: To investigate the feasibility of cine three-dimensional (3D) balanced steady-state free precession (b-SSFP) imaging combined with a non-local means (NLM) algorithm for image denoising in evaluating cardiac function in children with repaired tetralogy of Fallot (rTOF). Materials and Methods: Thirty-five patients with rTOF (mean age, 12 years; range, 7-18 years) were enrolled to undergo cardiac cine image acquisition, including two-dimensional (2D) b-SSFP, 3D b-SSFP, and 3D b-SSFP combined with NLM. End-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), and ejection fraction (EF) of the two ventricles were measured and indexed by body surface index. Acquisition time and image quality were recorded and compared among the three imaging sequences. Results: 3D b-SSFP with denoising vs. 2D b-SSFP had high correlation coefficients for EDV, ESV, SV, and EF of the left (0.959-0.991; p < 0.001) as well as right (0.755-0.965; p < 0.001) ventricular metrics. The image acquisition time ± standard deviation (SD) was 25.1 ± 2.4 seconds for 3D b-SSFP compared with 277.6 ± 0.7 seconds for 2D b-SSFP, indicating a significantly shorter time with the 3D than the 2D sequence (p < 0.001). Image quality score was better with 3D b-SSFP combined with denoising than with 3D b-SSFP (mean ± SD, 3.8 ± 0.6 vs. 3.5 ± 0.6; p = 0.005). Signal-to-noise ratios for blood and myocardium as well as contrast between blood and myocardium were higher for 3D b-SSFP combined with denoising than for 3D b-SSFP (p < 0.05 for all but septal myocardium). Conclusion: The 3D b-SSFP sequence can significantly reduce acquisition time compared to the 2D b-SSFP sequence for cine imaging in the evaluation of ventricular function in children with rTOF, and its quality can be further improved by combining it with an NLM denoising method.