• Journal of Environmental Health Sciences
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• v.5 no.1
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• pp.18-20
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• 1978

An experimental study was conducted to determine the quantity of contamination of organophosphrous pesticides accumulated in each human tissues. The samples used for this experiment were spleen, lung, heart, liver and kindney and those tissues were homogenized by a blender. The homogenized materials was extracted with mixed solvent, acetone/benzene (1:1) and cleaned up on a activated carbon column and determined by gas chromatography using AFID supported on 5% QF-1. The average recovery rate was 94% and the results obtained are summarized as follows. 1) The quantities of Malathin accumulated in each tissues were 0.53 ppm in spleen, 0.42 ppm in lung, 0.34 ppm in kidney, 0.19 ppm in heart and 0.19 ppm in liver. 2) Residues of pesticides in chronic or acute intoxicated tissues were highest in the spleen, decreasing in order of the lung, kidney, heart, and liver. 3) According to the above resuk we can conclude that the most proper material in detecting the pesticide is the spleen.

• Journal of Life Science
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• v.11 no.2
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• pp.111-120
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• 2001

The pathological aspects of purified ricin from the seeds of the castor oil plant, Ricinus communis, were examined, using light and transmission electron microscopy. ICR mice were exposed to ricin by peritoneal injection with 100 ng/1 $m\ell$ PBS(pH 7.0) mouse and histological observations on the liver, spleen, thymus, lung and heart were carried out at intervals up to 48 h after exposures. All the organs examined were damaged by ricin. Among the organs, the spleen and thymus; immune organs were the most sensitive to ricin, whereas the effect delayed in the liver, lung and heart. Furthermore, the immune cells in each organ were the most sensitive to ricin. Accordingly, the effect of ricin on the organs seems to be affected by the immune cells existed in each organ, In each organ, the immune cells showed apoptotic changes, while the capillary endothelial and parenchymal cells showed necrotic changes.

• Korean Journal of Veterinary Service
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• v.13 no.2
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• pp.189-195
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• 1990

During 9 months (March-November, 1989), observation of Leucocytozoon infection rate to blood and parenchymatous viscera (spleen, liver, heart) in Pusan, Gyeongnam (Kimhae, Yangsan) districts slaughtered chicken and the results obtained were as follow : 1. Among the blood smear sample of 213 heads of the chicken, 43 heads (20.2%) were infected with Leucocytozoon 2nd stage gametocyte and 4 heads (1.9%) were mixed infected with Leucocytozoon 5th stage gametocyte. 2. In histopathological detection of schizont in tissues section of spleen, liver and heart, there were 16.7% in spleen, 5.6％ in liver and 9.1％ in heart, mean detection rate were 10.6%. Spleen had the highest detection rate of schizont. 3. In seasonal-related Infection rate, summer was higher than spring.

• Journal of Korean Medical classics
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• v.22 no.1
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• pp.61-70
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• 2009

The five viscera[五藏], one of the key concepts from Traditional Oriental Medicine in understanding the nature of human body, endows the characteristic of five phases[五行] on the five representative organs, based on the five phases theory[五行論]. Although the theory from "Geummun-Sangseo(今文尙書)" which states the order of 'liver-mok[肝木] heart-hwa[心火] pancreas-to[脾土] lung-geum[肺金] kidney-su[腎水]' is now widely approved by present-day academics concerning arrangement of five changes and the five viscera, there are some other less-known theories of arrangement. "Gomun-Sangseo[古文尙書]" had suggested the order of 'pancreas-mok[脾木] lung-hwa[肺火] heart-to[心土] liver-geum[肝金] kidney-su[腎水]', which was never practiced, and "Dong-uisusebowon(東醫壽世保元)" of Ijema(李濟馬) expressed the theory of 'lung-mok[肺木] pancreas-hwa[脾火] heart-to[心土] liver-geum[肝金] kidney-su[腎水]'.

• Environmental Analysis Health and Toxicology
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• v.10 no.1_2
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• pp.15-20
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• 1995

The effects of volatile substances inhalation on lactate dehydrogenase and cholinesterase in rats were investigated. Male Sprague-Dawley rats were exposed to marketed odorant, ethyl acetate and ethyl ether for 15 days. Enzyme activities were measured in serum and several tissues such as liver, lung, brain, heart, kidney and muscle to find differences of effects according to the organ. Cholinesterase activity in serum and most of tissues revealed time-dependent decrease in the case of marketed odorant inhalation. Especially in heart and kidney significant decrease was observed. Ethyl acetate exposure to rats revealed also decrease in serum and all tissues by 40% to 60%. Ethyl ether inhalation showed significant decrease by 30% to 50%. Lactate dehydrogenase activity was markedly increased in serum and similarly in heart, brain and kidney by exposure to marketed odorant. No changes were observed in liver. Ethyl acetate exposure to rats revealed increase in serum by about 200%, compared to normal group and in other tissues by 40% to 70% except in liver and muscle. Ethyl ether inhalation showed significant increase in serum by about 100%. There was no change in 'liver and slight increase in muscle.

• Journal of Haehwa Medicine
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• v.13 no.1
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• pp.107-128
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• 2004

This thesis is focused to get treatment on climacteric syndrome through literary study. The results are followed as below. 1. The climacteric syndrome is beginning with lowering of secretion of female hormone. It's not understood as abnormal disease but as normal phenomenon. 2. The causes of climacteric syndrome are defined as deficiency of the Kidney, stagnation of Liver, disharmony between Heart and Kidney, insufficiency of both the Heart and the Spleen, blood stagnation. 3. The causes of climacteric bleeding are continuous with overstrain, injury of the five emotions, blood heat, deteriorating blood. 4. The treatment of climacteric syndrome are mainly nutrition of Kidney and Liver, that of Kidney heat, descending Yang of Liver, nutrition of blood of heart, having a comunication with Kidney and Heart, nutrition of Spleen and Stomarch. 5. For the prescriptions on climacteric syndrome, the treatments such as Jaguium(左歸飮), Wooguium(右歸飮), Soyosan(逍遙散加減), Jibakjihwangtang(知柏地黃湯加減), Esuntang(二仙湯), Ejihwan(二至丸加味), Sihogayonggolmoryutang(柴胡加龍骨牡蠣湯加減) are used. And the acupuncture points such as Conception Channel, the Spleen Channel, the Urinary Bladder Channel, the Kidney Channel which are related to the lower belly of woman.

• Korean Journal of Veterinary Service
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• v.17 no.2
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• pp.114-121
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• 1994

Clinically healthy 12 female Manina breed chicken (6 of 75 days old : group 46 of 145 days old： group B, female) were examined to establish physiological basic data on organ tissues total Creatine phosphokinase (CPK) activities and CPK isoenzymes fractions. The tissues examined were the Lung, Heart, Liver, Proventriculus, Gizzard, Duodenum, Colon and Muscle. The results obtained were summarized as follows : 1. Total CPK activities were high with decreasing order of the Muscle > Proventriculus >Giz-zard >Heart >Duodenum> Colon >Lung >Liver in group A and Muscle >Proventriculus >Giz-zard >Heart > Colon >Duodenum > Lung > Liver in group B. Significance of total CPK activities in group difference was only found Colon, group B showed higher values than that of group A (p< 0.01). 2. In the pattern of CPK isoenzymes fractions, Lung, Heart, Liver, Proventriculus, Gizzard, Duodenum and Muscle were high with decreasing order of CK2 >CK3, Colon showed the pattern with decreasing order of CK3 >CK2. Significance of CPK isoenzymes fractions in group difference was only found Liver, CK2 in group B(P<0.01) and CK3 in group A(P<0.01) were higher than that of the other group.

• Journal of Preventive Medicine and Public Health
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• v.26 no.2 s.42
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• pp.231-250
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• 1993

Thirty five male Sprague-Dawley rats were treated with cadmium chloride solution ranging from 0.2 to 3.2mg $CdCl_2/kg$ by intravenous single injection. At 48 hours after administration of cadmium, total cadmium, MT bound cadmium and histopathologic finding in liver, kidney, lung, heart, testis, metallothionein in liver, kidney and total cadmium in bleed were examined. Tissue cadmium concentration was highest in liver, followed by in kidney, heart, lung and testis. Cadmium bound to rnetallothionein (MT-Cd) and ratio of MT-Cd to total cadmium were increased in liver and kidney dependently of cadmium exposure dose, but not significantly changed in other organs. On histopathologic finding, the most susceptible organ was heart in considering cadmium exposed dose, but testis in considering cadmium concentration. Blood cadmium concentration was increased with dose-dependent pattern, and significantly correlated with tissue cadmium concentration, so that we may estimate tissue cadmium concentration by measurement of blood cadmium concentration. Metallothionein in liver and kidney was increased with dose-dependent pattern, higher in liver than in kidney, and was significantly correlated with tissue cadmium concentration. However, metallothionein induction efficiency of tissue cadmium(${\mu}g\;MT/{\mu}g\;Cd$) was eater in liver than in kidney, and reverse to tissue concentration or exposed dose of cadmium.

• Korean Journal of Exercise Nutrition
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• v.23 no.1
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• pp.21-27
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• 2019

[Purpose] In the present pilot study, we aimed to investigate the effects of the Silverrobics exercise program, which is similar to aerobic dance, on the factors related to glucose metabolism and liver enzymes. [Methods] Eight elderly women with obesity and impaired fasting glucose participated in the Silverrobics exercise program (60 minutes per session for five times a week for 8 weeks). The program was conducted at 50-60% of the heart rate reserve at 1 to 2 weeks and at 60-80% of the heart rate reserve at 3 to 8 weeks. To verify the effect of this 8-week exercise program on glucose metabolism and liver enzymes, blood analysis at pre- and post-training was performed. [Results] After the Silverrobics exercise program, there were significant decreases in the glucose (p<0.05), glycated hemoglobin A1c (p<0.05), 1,5-anhydroglucitol (p<0.05), and insulin levels (p<0.01) and homeostatic model assessment of insulin resistance score (p<0.05). However, there were no significant effects on the liver enzymes, except for alkaline phosphatase. The alkaline phosphatase level increased after the Silverrobics exercise program (p<0.05). [Conclusion] Although the Silverrobics exercise program had no beneficial effects on the liver enzymes, it may play an important role in preventing liver diseases considering the effects on glucose metabolism.

• The Korean Journal of Pharmacology
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• v.8 no.2
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• pp.41-47
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• 1972

Fluorides were supposed to exert a stimulatory action on the catecholamine release. In this study, the authors attempted to investigate the action of sodium fluoride on the catecholamine release from the isolated perfused cow adrenal gland and rat heart. And also the inhibitory effect of sodium fluoride on the monoamine oxidase activity in rat heart and liver mitochondria was investigated. The monoamine oxidase activity was measured by the conversion of benzylamine to benzaldehyde. The results obtained were follows; 1. Sodium fluoride stimulated the release of catecholamine from the isolated perfused cow adrenal gland and rat heart. 2. Sodium fluoride inhibited the rat heart and liver mitochondrial monoamine oxidase activity.