• 한국수의병리학회:학술대회논문집
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• 한국수의병리학회 2002년도 추계학술대회초록집
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• pp.136-136
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• 2002

A rat (Rottus norvegicus) infected with C. hepatica was trapped incidentally. At necropsy, grossly yellowish-white nodules were scattered on the liver surface. Microscopically, granulomatous and fibrotic nodules containing eggs and/or adult worms of C. hepatica were detected in the liver. Septal fibrosis forming pseudolobules was observed as a diffuse change throughout the liver. In double staining with immunostaining of -SMA and toluidine blue, myofibroblasts and mast cells were generally observed within the fibrous septa with mast cells being along the myofibroblasts. In this case, we hypothesized that myofibroblast and mast cell might playa role in septal fibrosis of rat liver induced by C. hepatica infection.

• Neonatal Medicine
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• 제28권2호
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• pp.83-88
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• 2021

Treatment guidelines for postnatal cytomegalovirus (pCMV) infection in preterm have not been established yet. Neutropenia, thrombocytopenia, hepatitis, colitis, and sepsis-like disease are among the clinical manifestations, which range from moderate to serious. We present a case of autopsy diagnosed as pCMV infection in a premature infant delivered at gestational age of 24 weeks and 5 days. On the 7th and 14th days of birth, urinary CMV polymerase chain reaction samples were negative, ruling out congenital CMV infection. However, autopsy examination revealed that the patient had disseminated pCMV infection. CMV inclusion bodies were found in the majority of tissues, including the lung, liver, pancreas, breast, kidney, and adrenal gland, but not the placenta. The thymus exhibited significant cortical atrophy and T-cell immunodeficiency, possibly induced by dexamethasone treatment for bronchopulmonary dysplasia or by pCMV infection itself. If dexamethasone treatment is extended or high doses are considered, it may be beneficial to test the CMV infection status to prevent aggravation of infection. This case demonstrates that, despite the low prevalence, pCMV infection should be considered a differential diagnosis in preterm if other conditions or etiology cannot justify clinical deterioration.

• Pediatric Infection and Vaccine
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• 제23권2호
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• pp.137-142
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• 2016

여러 기관을 침범하는 중증 주산기 거대세포바이러스 감염은 극저출생체중아 또는 면역저하 환자 이외의 경우에는 매우 드물다. 저자들은 재태연령 34주 6일, 2,460 g으로 출생한 후기 미숙아에서 다기관(중추신경계, 간, 폐, 위장관)을 침범한 거대세포바이러스에 의한 주산기 감염을 의심하고 ganciclovir 투약 후 회복된 증례를 경험하여 문헌 보고하는 바이다.

• 한국식품위생안전성학회지
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• 제12권4호
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• pp.300-303
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• 1997

The present study was carried out to know the distribution of freshwater mollusk on the chinese liver fluke in the middle of August, 1997 at the upper area of Kyungan stream located in Yongin Kun, Kyungki province. The snails were collected from the shallow and irrigation route in a rural area located along the upper area of Kyungan stream. The snails collected by hand were brought to the laboratory and cercariae naturally shed from the snails, Parafossarulus manchouricus were examined. Parafossarulus manchouricus is medically important intermediated host of the transmission of digenetic trematoda to human. Each snail was placed in aerated tap water for the detection of ceracariae and examined for expelled cercariae. Infection rate of the cercariae of Clonorchis sinensis was 3 (1.5%) among 195 individuals collected in the habitat. The identification of the cercaria of Clonorchis sinensis was performed as described by Komiya and Tajimi.

• Asian-Australasian Journal of Animal Sciences
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• 제14권1호
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• pp.96-100
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• 2001

Three commercial strains bred in the US (Hubbard), Holland (Lohman), and Canada (Shaver) and Balady breed of chickens were orally infected with $10^6$ cfu of Salmonella gallinarum per chick. Chicks were compared for weight gain, feed intake, feed conversion ratio, mortality rate and contamination of the liver, spleen and intestine with Salmonella gallinarum on the day of slaughter. The Balady chicks had significantly the lowest mortality rate (p<0.01) and weight gain (p<0.001) and poorest feed conversion ratio (p<0.001). Salmonella gallinarum could be shed from the liver, spleen and intestine with alternative rates in all strains. Lohman was the most resistance over the other two commercial strains, while Hubbard had the highest susceptibility. The Balady chicks were the most resistance. However, they may serve as a possible reservoir of Salmonella gallinarum and it may play a role of spreading the infection to the commercial farms in Jordan.

• 한국동물위생학회지
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• 제21권4호
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• pp.407-411
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• 1998

Aspergillosis, caused by infection with Aspergillus fumigatus and less commonly by other Aspergillus species, is a prevalent and costly respiratory disease of poultry, In a flock of chicks, the number of birds, 4∼5 months old, had become gradually emaciated and subsequently died. Gross necropsy revealed multiple granulomatous masses on the abdominal serosa. The masses, 4∼15 mm in size, were attached on mainly intestinal wall. Also, the smaller masses in size were on mesentery and pancreas. However, only a few small white nodules were scattered throughout liver and lung in few samples. Microscopically, the mass were granulomatous with a central area of necrosis containing numerous septate, branched fungal hypae consistent with Aspergillus sp. These were surrounded by macrophages, giant cells, lymphocytes and fibrous tissues. Nodular lesions of liver and lung were seemed to spread hemotogenously from intestine and the possible route of infection was speculated by oral. This report is a Aspergillus-induced granuloma limited to the serosa of abdominal cavity, especially of intestinal wall.

• 한국동물위생학회지
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• 제21권4호
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• pp.385-390
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• 1998

A rabbit farm reared about 500 New Zealand White in Kwangju city was occurred Eimeria stiedae infection. Morbidity and cumulative mortality were more than 39% and 14%, respectively, from May, 1997 to March, 1998. Most of cases with severe diarrhea were belong to younger than 2-month old. In necrospy, there were multifocally white nodules with about 1-5mm in diameter on the liver surface and dark greenish mucous exudate in intestinal lumen. Main microscopic lesions included marked hyperplasia of the bile duct epitheilia containing different developmental stages of Eimeria stiedae and inflammatory cell infiltration, and the degeneration of small intestinal epithelia. Many oocysts of Eimeria stiedae were detected in the intestinal contents and epithelia, the feces, the bile juice, the bile duct and the liver.

• Tuberculosis and Respiratory Diseases
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• 제53권1호
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• pp.79-84
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• 2002

저자들은 알코올성 간경변증 환자에서 발견된 폐 노카르디아 감염증 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• Parasites, Hosts and Diseases
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• 제52권6호
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• pp.621-629
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• 2014

Malaria is one of the most widespread infectious diseases of tropical countries with an estimated 207 million cases globally. In India, there are endemic pockets of this disease, including Aligarh. Hundreds of Plasmodium falciparum and P. vivax cases with severe pathological conditions are recorded every year in this district. The aim of this study is to find out changes in liver enzymes and kidney markers. Specific diagnosis for P. falciparum and P. vivax was made by microscopic examination of Giemsa stained slides. Clinical symptoms were observed in both of these infections. Liver enzymes, such as AST, ALT, and ALP, and kidney function markers, such as creatinine and urea, were estimated by standard biochemical techniques. In Aligarh district, P. vivax, P. falciparum, and mixed infections were 64%, 34%, and 2%, respectively. In case of P. falciparum infection, the incidences of anemia, splenomegaly, renal failure, jaundice, and neurological sequelae were higher compared to those in P. vivax infection. Recrudescence and relapse rates were 18% and 20% in P. falciparum and P. vivax infections, respectively. Liver dysfunctions and renal failures were more common in P. falciparum patients, particularly in elderly patients. Artesunate derivatives must, therefore, be introduced for the treatment of P. falciparum as they resist to chloroquine as well as sulfadoxine-pyrimethamine combinations.

• Parasites, Hosts and Diseases
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• 제51권1호
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• pp.31-36
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• 2013

An overview of the epidemiological, biological, and clinical studies of Taenia and taeniasis in Taiwan for the past century is presented. The phenomenal observations that led to the discovery of Taenia asiatica as a new species, which differ from Taenia solium and Taenia saginata, are described. Parasitological surveys of the aborigines in Taiwan revealed a high prevalence of taeniasis, which might be due to the culture of eating raw liver of hunted wild boars. Chemotherapeutic deworming trials involving many patients with taeniasis were discussed. Praziquantel was found to be very effective, but sometimes complete worms could not be recovered from the feces after treatment, probably due to the dissolution of the proglottids. Atabrine, despite some side effects, can still be used, in properly controlled dosages, as the drug of choice for human T. asiatica infection if we need to recover the expelled worms for morphological examinations. Research results on the infection of T. asiatica eggs from Taiwan aborigines in experimental animals were also noted. Since the pig serve as the natural intermediate host of T. asiatica and the predilection site is the liver, a differential comparison of other parasitic pathogens that might cause apparently similar lesions is also presented.