• Clinical and Experimental Pediatrics
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• 제53권10호
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• pp.880-885
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• 2010

Purpose: The recent trends of multiple births (MBs) conceived by assisted reproductive technology (ART) in Korea were analyzed as well as the relationship with maternal age, especially advanced maternal age. Methods: Data were obtained from the Korean Statistical Information Service and annual ART reports from the ART committee of the Korean Society of Obstetrics and Gynecology. Results: MBs increased from the early 1990s; there was a 275% increase by 2008. The number of total live births was 448,153 and MBs accounted for 10,767; the MB rate was 24.0% in 2006. Among 2,326 deliveries conceived by ART, multiple deliveries accounted for 786 (33.8%). The total number of live births with ART was 3,125 and 1,585 (50.7%) of them were MBs. During 2006, 14.7% of the entire MBs in Korea were associated with ART. The proportion of women of advanced maternal age was much higher in the ART group than in the total live birth group. Conclusion: MBs in women of advanced maternal age have been increasing in Korea with the use of ART. The results of this study showed that ART was a significant factor associated with the increase in MBs in Korea.

• Journal of Preventive Medicine and Public Health
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• 제52권2호
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• pp.123-130
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• 2019

Objectives: The aim of this study was to evaluate the impact of shifts in maternal age and parity on the increasing trends in the low birth weight (LBW) and very low birth weight (VLBW) rates from 2005 to 2015 in South Korea. Methods: Data from 4 993 041 live births registered with Statistics Korea during the period between 2005 and 2015 were analyzed. Applying a modified standardization method, we partitioned the total increment in the LBW and VLBW rates into (1) the increase in the LBW and VLBW rates due to changes in the maternal age and parity distribution (AP-dis) and (2) the increase due to changes in the age-specific and parity-specific rates (AP-spe) of LBW and VLBW for singleton and multiple births, respectively. Results: During the study period, the total increment in the LBW and VLBW rates was 1.43%p and 0.25%p, respectively. Among singleton births, changes in the AP-dis accounted for 79% (0.34%p) and 50% (0.06%p) of the total increment in the LBW and VLBW rates, respectively. Meanwhile, among multiple births, changes in the AP-dis did not contribute to the increase in the LBW and VLBW rates, with 100% of the increase in the LBW (1.00%p) and VLBW (0.13%p) rates being attributed to changes in the AP-spe. Conclusions: This study demonstrated that shifts in maternal age and parity were prominent contributors to the increase in the LBW and VLBW rates among singleton births between 2005 and 2015 in South Korea.

• Asian-Australasian Journal of Animal Sciences
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• 제8권1호
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• pp.29-35
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• 1995

A selection experiment with Romney Marsh sheep was used to evaluate correlated responses to selection. The selected flock was formed in 1979 by the Romney Group Breeders where selection was for prolificacy, defined as the number of live lambs born per ewe joined per year and a randomly selected control flock was established in 1982. Selection for prolificacy resulted in (i) increased ewe fertility, (ii) increased ewe ovulation rate, (iii) increased ewe litter size, (iv) decreased ewe body weight, (v) decreased lamb birth weight and (vi) decreased lamb 8-week weight. The rates of correlated responses per year respectively for ewe fertility, ewe ovulation rate, ewe litter size, ewe body weight, lamb birth weight and lamb 8-week weight were 0.033(0.002), 0.043(0.016), 0.019(0.005), -0.017(0.066), -0.055(0.025) and -0.150(0.057).

• Imaging Science in Dentistry
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• 제41권4호
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• pp.167-170
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• 2011

Ellis-van Creveld syndrome is a rare congenital genetic disorder having autosomal recessive inheritance. It is a syndrome affecting the Amish population of Pennsylvania in USA with prevalence rate of 1/5,000 live at birth. In non-Amish population, the birth prevalence is 7/1,000,000. The syndrome is characterized by bilateral postaxial polydactyly of the hands, chondrodysplasia of long bones resulting in acromesomelic dwarfism, ectodermal dysplasia affecting nails as well as teeth and congenital heart malformation. There were very rare reports of this syndrome in dentistry. The present case focuses on the striking and constant oral findings of these patients, which are the main diagnostic features of this syndrome. Since the oral manifestations affect the esthetic, speech, and jaw growth of the child, the dentists have an important role to play in proper management of such case.

• 한국환경보건학회지
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• 제34권5호
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• pp.361-368
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• 2008

Objective to assess whether exposure to air pollutants is associated with postneonatal infant death, using a timeseries methodology, between 1999 and 2003 in Seoul, Korea.. Methods We investigated the short-term effects of air pollution for 548,725 live births during the study period. The daily count of postneonatal infant deaths from all causes and from SIDS (sudden infant death syndrome) by birth order was analyzed by a Generalized Additive Poisson model, with controlling for the effects of seasonal trends, air temperature, relative humidity, barometric pressure, and day of the week as covariates. Results During the study period, we observed 699 deaths from all causes and 47 deaths from SIDS. We did not find any significant associations between daily mortality and ambient levels of air pollutants except for CO and $NO_2$. The estimated relative risk of postneonatal infant death from all causes was 1.17 (95% CI=1.04-1.32) and 1.16 (95% CI=1.03-1.29) by IQR (interquartile range) for CO and $NO_2$ respectively. Also, we observed no clear trend of the mortality effects of air pollution by birth orders. Conclusion In conclusion, our findings suggest that air pollution, in general, influenced adversely postneonatal infant death from all-cause and SIDS although it was not statistically significant. This study may support that the rationale.

• Asian-Australasian Journal of Animal Sciences
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• 제15권6호
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• pp.828-833
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• 2002

Thirty mature pregnant ewes of the Phan Rang breed with an initial live weight of 30 to 45 kg were used to compare the effects of three different diets in late pregnancy on ewe and lamb performance. All diets contained 20% of whole sugar cane, 16% rice bran, 26% cassava root and 6% molasses urea block. The remaining 32% of dry matter consisted of Jackfruit (JF diet), 16% each of Jackfruit and Cassava foliage (JF+CS diet) or Jackfruit and Flemingia foliage (JF+FM diet). The diets were fed at 3.5% of actual BW of the individual animal. The foliages were offered at 120% of the amount decided in the diets of the requirements. The JF+CS diet resulted in significantly higher feed intake than the JF diet, and also a higher feed intake than the JF+FM diet, but this difference was not significant. The ewe weight changes during the last 8 weeks of pregnancy, or from start to 24 h after lambing, were significantly different. The highest weight gain was obtained from the ewes fed the JF+CS diet. Diets had no effect on weight changes of ewes during 3 weeks after lambing but a significant effect on the litter birth weight, with the JF+CS diet giving the highest litter birth weight. There was, however, no effect on the litter weight at 21 days or litter growth rate from birth to 21 days due to the experimental diets.

• 한국발생생물학회지:발생과생식
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• 제20권3호
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• pp.219-225
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• 2016

Most of the commercial devices for vitrification are directly immersed into the warming solution (WS) for increasing of warming rate. However, the previous modified cut standard straw (MCS) which has reported is difficult to immerse into the WS. The aim of this study was to investigate whether the long cut straw (LCS) could be useful as a stable tool for vitrified-warmed human blastocysts. A total of 138 vitrified-warmed cycles were performed between November 2013 and November 2014 (exclusion criteria: women ${\geq}38$ years old, poor responder, surgical retrieval sperm, and severe male factor). The artificial shrinkage was conducted using 29-gauge needles. Ethylene glycol and dimethyl sulfoxide (7.5% and 15% (v/v)) were used as cryoprotectants. Freezing and warming were conducted using the LCS tool. The cap of LCS was removed using the forceps in the liquid nitrogen ($LN_2$) and then directly immersed into the first WS for 1 min at $37^{\circ}C$ (1 M sucrose). Only re-expanded blastocysts were transferred after it was cultured in sequential media for 18-20 h. A total of 294 blastocysts were warmed, and all were recovered (100%). Two hundred eighty-five embryos were survived (96.9%). The vitrified-warmed blastocysts of all patients were transferred without any cancellation. We were able to achieve a reasonable implantation (24.2%), following by clinical pregnancy (36.2%), which then continued to ongoing pregnancy (36.2%), and live birth (31.2%). Using LCS is achieved the acceptable rates of survival, pregnancy and live birth. Therefore, the LCS could be considered as a stable and simple tool for human embryo vitrificaton.

• Journal of Preventive Medicine and Public Health
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• 제20권2호
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• pp.322-330
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• 1987

출생시 체중변화의 양상과 산모의 연령 및 출산순위와의 관계를 알아보기 위하여 1977년 1월부터 1986년 12월까지 부산시내 1개 종합병원에서 총 14,346건의 분만 가운데 20주이후에 출생한 단태아 13,634명을 대상으로 산실의 분만대장에서 신생아의 출생순위분포, 산모의 연령분포, 신생아의 체중분포와 평균체중, 산모의 연령과 출산순위에 따른 저 체중아와 과체중아의 출생을, 유산경험율과 사산율을 조사하였다. 신생아의 평균체중은 1979년에는 남아 3074gm, 여아 2985gm에서 1986년에는 남아 3266gm, 여아 3210gm 으로 증가하였고, 저체중아의 발생율은 1977년 7.2%에서 점차 증가하여 1980년에는 10.4%였으나 그후 점점 감소하여 1986년에는 6.5%였다. 과체중아의 발생율은 2,9%에서 4.6%사이로 평균 3.9%였으며 특별한 변화 양상은 볼 수 없었다. 유산을 경험 한 산모의 비율은 1979년에 51.6%에서 1986년에는 45.1%로 감소하였고, 사산율도 1977년에는 2.6%에서 1986년에는 1.5%로 감소했다. 이와같은 변화에는 가족계획 실천율의 증가와 결혼연령의 상승으로 $25{\sim}34$세사이 산모의 1과 2순위 출생아가 차지하는 비율이 증가한 것이 크게 영향을 미친 것으로 생각되며, 과체중아의 비율은 늘지 않고 오히려 저체중아의 출생율은 감소되어 전체적으로 신생아의 건강이 향상되고 있는 것으로 나타났다.

• Clinical and Experimental Pediatrics
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• 제55권8호
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• pp.280-285
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• 2012

Purpose: The authors analyzed the trend from the birth-related statistics of high birth weight infants (HBWIs) over 50 years in Korea from 1960 to 2010. Methods: We used 2 data sources, namely, the hospital units (1960's to 1990's) and Statistics Korea (1993 to 2010). The analyses include the incidence of HBWIs, birth weight distribution, sex ratio, and the relationship of HBWI to maternal age. Results: The hospital unit data indicated the incidence of HBWI as 3 to 7% in the 1960's and 1970's and 4 to 7% in the 1980's and 1990's. Data from Statistics Korea indicated the percentages of HBWIs among total live births decreased over the years: 6.7% (1993), 6.3% (1995), 5.1% (2000), 4.5% (2000), and 3.5% (2010). In HBWIs, the birth weight rages and percentage of incidence in infants' were 4.0 to 4.4 kg (90.3%), 4.5 to 4.9 kg (8.8%), 5.0 to 5.4 kg (0.8%), 5.5 to 5.9 kg (0.1%), and >6.0 kg (0.0%) in 2000 but were 92.2%, 7.2%, 0.6%, 0.0%, and 0.0% in 2009. The male to female ratio of HBWIs was 1.89 in 1993 and 1.84 in 2010. In 2010, the mother's age distribution correlated with low (4.9%), normal (91.0%), and high birth weights (3.6%): an increase in mother's age resulted in an increase in the frequency of low birth weight infants (LBWIs) and HBWIs. Conclusion: The incidence of HBWIs for the past 50 years has been dropping in Korea. The older the mother, the higher was the risk of a HBWI and LBWI. We hope that these findings would be utilized as basic data that will aid those managing HBWIs.

• 한국주거학회논문집
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• 제9권3호
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• pp.69-77
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• 1998

This study has been performed to analyze living arrangement in later life. In this study, 276 Koreans aged 60 or more were interviewed for their current household structure. The results are drawn as follows: 1. Of all the households with at least one person aged 60 or more, those living in three generations account for the largest proportion, 39.9 percent. For the regional difference, the rate was slightly higher in urban areas than in rural areas. 2. 48.7% of the subjects living in owned homes were households with elderly only, but only 23% of those living in rented homes are elderly only. Overall, the rate of elderly-only households becomes the highest for those living in owned single structure homes. This result indicates that the elderly with higher economic status are more likely to live without children than others. 3. As for birth order, those who grew up as the first child are most likely to live in elderly-only households, while others are in three generation homes. 4. The elderly with few children are more likely to live independently than those with many children, not because they are without dependable children, but because spend less resource for childbearing and therefore are more independent. 5. Overall in this, it is supported that socioeconomic status and independability are more influential factors on living arrangement of the elderly than regional or emotional factors.