• Journal of Preventive Medicine and Public Health
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• 제57권3호
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• pp.212-222
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• 2024

Objectives: Epilepsy is a chronic disease that requires long-term treatment and intervention from health workers. Medication adherence is a factor that influences the success of therapy for patients with epilepsy. Therefore, this study aimed to analyze the role of pharmacists in improving the clinical outcomes of epilepsy patients, focusing on medication adherence. Methods: A scoping literature search was conducted through the ScienceDirect, PubMed, and Google Scholar databases. The literature search included all original articles published in English until August 2023 for which the full text was available. This scoping review was carried out by a team consisting of pharmacists and neurologists following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) Extension for Scoping Reviews and the Joanna Briggs Institute guidelines, including 5 steps: identifying research questions, finding relevant articles, selecting articles, presenting data, and compiling the results. Results: The literature search yielded 10 studies that discussed pharmacist interventions for patients with epilepsy. Five articles described educational interventions involving drug-related counseling with pharmacists. Two articles focused on similar pharmacist interventions through patient education, both verbal and written. Three articles discussed an epilepsy review service, a multidisciplinary intervention program involving pharmacists and other health workers, and a mixed intervention combining education and training with therapy-based behavioral interventions. Conclusions: Pharmacist interventions have been shown to be effective in improving medication adherence in patients with epilepsy. Furthermore, these interventions play a crucial role in improving other therapeutic outcomes, including patients' knowledge of self-management, perceptions of illness, the efficacy of antiepileptic drugs in controlling seizures, and overall quality of life.

• 고전문학과교육
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• 제32호
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• pp.159-191
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• 2016

본 논문에서는 필자가 서울시내 A대학에서 2014년 2학기 국어국문학과 전공선택 과목인 <고전과 창작> 수업시간에 실시한 강의에 근거하여, 수업시간에 실행한 재창작 수업의 과정을 소개하고, 그 과정에서 보여주는 대학생들의 자기성찰 양상을 탐색하고자 하였다. 수업에 참여한 대학생들이 3회의 발표를 통해 만들어낸 작품을 주 분석 대상으로 삼았다. 2장에서는 고전작품 재창작을 위한 수업 진행의 과정으로서 '재창작 작품 선정 배경 및 기획의도 발표', '원작에 대한 분석 및 재창작 사례 탐색', '작품 재창작 및 메타글쓰기'에 대해 논의하였다. 3장에서는 작품 재창작 과정을 통한 대학생의 자기성찰 양상을 탐색해보았다. 학생들이 재창작하고자 하는 고전 작품을 선정하고, 분석하고, 재창작하고, 재창작한 작품에 대한 자기평가에 이르는 과정을 통해서 그들이 가지고 있는 삶에 대한 태도가 어떠한지, 문제가 있다면 그 문제를 대하는 태도와 경향성은 어떠한지 살펴보는 데 역점을 두었다. 수업에 참여한 학생들은 재창작의 대상으로 제각기 서로 다른 작품을 선택하였지만, 이번 논의에서는 <심청전>을 재창작한 두 명의 대학생을 대상으로, 그들이 창작한 작품과 자기 성찰 양상을 비교분석하였다. 그리하여 아버지와의 관계 양상에 따른 창작결과물의 특성에 대해 살펴볼 수 있었다. 고전을 활용한 보다 효과적인 재창작 수업을 위해 작품을 선정하고 보다 체계적이고 다양한 재창작 방법론에 대한 모색이 필요할 것이다. 그러나 고전을 활용한 재창작 수업은 원작의 작품서사를 활용하기 때문에 창작에 대한 부담을 줄일 수 있었고, 자기성찰의 매개가 되는 고전작품을 통해 평소 본인이 고민하는 문제에 대한 깊이 있는 탐색이 가능하다. 또한 공개적인 작품 발표를 통해 보다 객관적인 입장에서 자기서사를 탐색할 수 있고, 피드백을 통해 다른 사람의 의견을 수렴하는 것이 가능하다는 점을 확인할 수 있었다.

• Radiation Oncology Journal
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• 제32권2호
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• pp.99-102
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• 2014

We present a case of unresectable cancer of the base of tongue treated with hypofractionated 3D conformal radiotherapy and concomitant chemotherapy. Based on the excellent tumour response in this radiotherapy regimen and international experience in short course treatments we shortly reviewed, we propose that this therapeutic approach could be considered in a curative setting for patients unsuitable for the a standard long course radiochemotherapy schedule.

• IMMUNE NETWORK
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• 제9권6호
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• pp.209-235
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• 2009

There has been an explosion of literature focusing on the role of regulatory T (Treg) cells in cancer immunity. It is becoming increasingly clear that Treg cells play an active and significant role in the progression of cancer, and have an important role in suppressing tumor-specific immunity. Thus, there is a clear rationale for developing clinical strategies to diminish their regulatory influences, with the ultimate goal of augmenting antitimor immunity. Therefore, manipulation of Treg cells represent new strategies for cancer treatment. In this Review, I will summarize and review the explosive recent studies demonstrating that Treg cells are increased in patients with malignancies and restoration of antitumor immunity in mice and humans by depletion or reduction of Treg cells. In addition, I will discuss both the prognostic value of Treg cells in tumor progression in tumor-bearing hosts and the rationale for strategies for therapeutic vaccination and immunotherapeutic targeting of Treg cells with drugs and microRNA.

• Journal of Acupuncture Research
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• 제34권3호
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• pp.59-69
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• 2017

Objectives : This study analyzed the current status of randomized controlled trials (RCTs) of miniscalpel acupuncture for lumbar spinal stenosis (LSS) in China. Methods : A literature search was performed using the China National Knowledge Infrastructure (CNKI) database. All studies up to June 7th, 2017 were searched. The quality of included RCTs was assessed with the Jadad scale. Results : Five RCTs were finally included in this review. The overall quality of the RCTs was assessed as low. All articles evaluated miniscalpel acupuncture as monotherapy or in combination with filiform needle therapy, drug injection therapy, Tuina treatment, thermal coagulation therapy, or spinal decompression. Miniscalpel acupuncture as monotherapy or adjunctive therapy showed greater therapeutic effect and fewer adverse effects. Conclusion : Miniscalpel acupuncture is a safe and effective nonpharmacological treatment for LSS. However, high-quality studies with consistent treatment protocols are needed to confirm these findings.

• 대한통합의학회지
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• 제3권2호
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• pp.1-8
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• 2015

Purpose: This study was conducted to know the evidence case to assessment about literatures of extensor carpi radialis therapeutic strategy of tennis elbow about dysfunction wrist extension with anatomy, biomechanic and function. Method: Patient was received the physical therapy program with medication for two weeks. Physical therapy program consists of strengthening exercise, stretching exercise and extracopereal shock wave therapy. Results: Patients could do computer and house works at three weeks significant with improved pain. The amounts used repetitive muscle was reduced slowly over a period of a day or two days for wrist moving. Wrist flexor strengthening exercise and could reduced the wrist extensor injury. Conclusion: Clinicians certainly realized biomechanic effects and anatomy of extensor carpiradialis and elbow joint.

• IMMUNE NETWORK
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• 제8권4호
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• pp.107-123
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• 2008

It has now been well documented in a variety of models that T regulatory T cells (Treg cells) play a pivotal role in the maintenance of self-tolerance, T cell homeostasis, tumor, allergy, autoimmunity, allograft transplantation and control of microbial infection. Recently, Treg cell are isolated and can be expanded in vitro and in vivo, and their role is the subject of intensive investigation, particularly on the possible Treg cell therapy for various immune-mediated diseases. A growing body of evidence has demonstrated that Treg cells can prevent or even cure a wide range of diseases, including tumor, allergic and autoimmune diseases, transplant rejection, graft-versus-host disease. Currently, a large body of data in the literature has been emerging and provided evidence that clear understanding of Treg cell work will present definite opportunities for successful Treg cell immunotherapy for the treatment of a broad spectrum of diseases. In this Review, I briefly discuss the biology of Treg cells, and summarize efforts to exploit Treg cell therapy for autoimmune diseases. This article also explores recent observations on pharmaceutical agents that abrogate or enhance the function of Treg cells for manipulation of Treg cells for therapeutic purpose.

• 대한두경부종양학회지
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• 제1권1호
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• pp.81-86
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• 1985

A case of primary laryngeal non-Hodgkin's lymphoma is detailed with a review of the literature, on this rare site of presentation. Histologic findings and radio-therapeutic technique are included with longterm follow-up data. Local radiotherapy is a curative treatment of choice due to longterm NED survival with preservation of voice.

• 대한두경부종양학회지
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• 제28권2호
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• pp.132-134
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• 2012

Ectopic thyroid is an uncommon embryologic aberration characterized by the presence of thyroid tissue in a site other than its usual pre-tracheal location. Dual ectopic thyroid is extremely rare, only few cases have been reported in the literature. Physical examination, laboratory test and radiologic examinations are usually performed for the diagnosis and therapeutic plan of dual ectopic thyroid. We report a 36-year old female with dual ectopic thyroid in lingual and hyoid regions but without thyroid tissue in its normal area. The diagnosis was made through pathologic examination after surgical resection.

• 대한물리의학회지
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• 제2권1호
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• pp.85-91
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• 2007

Purpose : The purpose of this study is understanding of Rett Syndrome. Rett Syndrome is a common developmental - neurologic disorder that has been reported almost exclusively in female. Recently mutations in the gene encoding X-linked methyl-CpG binding protein 2 (MECP2) have been identified as the cause of Rett syndrome. Consistent with the diagnostic criteria, hand skills, verbal or non - verbal communication skills and common motor skills were lost during regression. Regression most commonly occurred between 12 and 18 months of age. Methods : This is a literature study with books, articles, web site for Rett syndrome international association. Results : There is a continuing need to further elucidate the pre- and post - regression features of Rett syndrome. Rett syndrome need to physical therapy, musical therapy, special education and medical interventions. Conclusion : There has not been therapeutic method to the root of Rett syndrome but our goal is relaxation of symptom and physical therapist's study of Rett syndrome.