• Title/Summary/Keyword: Liquid crystal, Biodegradatio

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Synthesis and Physical Properties of Bioc'ompatible and Biodegradable Chitin Derivatives V. -Biodegradation of liquid Crystalline Chitin Derivatives by Lysozyme- (생체적합성과 생분해성을 갖는 키틴유도체의 합성과 물성V -라이소자임에 의한 액정성 키틴 유도체의 생분해특성-)

  • 김선정;이영무
    • Journal of Biomedical Engineering Research
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    • v.15 no.1
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    • pp.89-96
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    • 1994
  • The ether-type chitin derivatives were synthesized by reacting chitin with chloropropane, propylene oxide and chloropropane diol to form propyl chitin(PPC), hydroxypropyl chitin(HPC) and dihydroxypropyl chitin(DHPC). These derivatives formed a lyotropic cholesteric liquid crystallinity in concentrations over 30 wt% solution in formic acid (99%). Cast films from liquid crystalline solutions were degraded by lysozyme in pseudo-extra cellular tluid(PECF)solutions, at pH 1.2, pH 6.7 and pH 8.2. Three ether-type chitin derivatives rapidly degraded within the first week, and showed a decreased mechanical strength in neutral pH range. Dihydroxypropyl chitin showed the best biodegradation among these derivatives.

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