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MANAGEMENT OF LESCH-NYHAN SYNDROME PATIENTS WITH SELF-MUTILATION BEHAVIOR USING THEIR TEETH : CASE REPORTS (레쉬니한 증후군(Lesch-Nyhan syndrome) 환자의 치아와 연관된 자해행동의 관리: 증례보고)

  • Lee, Ji-Mi;Lee, Sang-Ho;Lee, Nan-Young;Jih, Myeong-Kwan
    • The Journal of Korea Assosiation for Disability and Oral Health
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    • v.14 no.2
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    • pp.97-101
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    • 2018
  • Lesch-Nyhan syndrome is a rare X-linked recessive genetic disorder. During purine metabolism, the hypoxanthine guanine phosphribosyl transferase (HGPRT) enzyme is deficient causing phosphoribosyl transferase to accumulate and resulting in excessive uric acid. Clinical symptoms include hypercalcemia, choreoathetosis, spasticity, mental retardation, and self-injury to lips, tongue or fingers. This results not only in pain caused by the self-injury but also secondary infection of the wound site and the esthetic damage of the soft tissue defect. Dental treatments include conservative methods using intraoral appliances such as soft mouthguards, fixed lip bumpers, and occlusal guards, and invasive methods such as extraction of all teeth or forming an artificial anterior open bite. We report two cases of Lesch-Nyhan syndrome patients with self-mutilation behavior; one was treated with a preservative method using a soft mouthguard, and the other was treated with extraction of all teeth.

Growth Characteristic of Pinus densiflora by Soil Generated at Civil Works Site (현장발생토 활용 식재기반 조성유형별 소나무 생육 특성 평가)

  • Oh, Deuk-Kyun;Kim, Phil-Lip;Yoon, Yong-Han;Kim, Won-Tae
    • Journal of Environmental Science International
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    • v.28 no.8
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    • pp.655-667
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    • 2019
  • This research aims to identify the possibility of developing A horizon resources that can be used for construction and civil engineering work. As such, the utility of A horizon resources was examined by establishing planting ground through a mixture of soil layers and by analyzing the growth and development of Pinus densiflora. The physicochemical and physical properties of the soil were as follows: the A horizon was sandy clay loam, B horizon was sandy loam, and the mixture of two layers appeared as sandy loam, which was identical to the B horizon. The experimental groups did not show any significant difference in their physical properties of porosity and degree of water-stable aggregates. With regards to chemical properties, the A horizon as well as the mixture of A and B horizon showed acidity while the B horizon showed alkalinity. The figures of organic matter, total nitrogen, available phosphate, and replaceable potassium were greater as the A horizon content increased, whereas the figures of replaceable calcium, replaceable magnesium, and conductivity increased as the A horizon content decreased. As a result of the growth and development of Pinus densiflora in each planting ground, the final survival rates were all above 100%. However, the tree height and the rate of growth for the diameter of root were higher in the order of A horizon > A horizon + B horizon > B horizon,indicating that the increased A horizon content is related to the growth and development of Pinus densiflora. The treatment of soil with improvement agents, used to recover the functions of in-situ soil showing poor growth and development, did not have a clear impact on the soil texture and porosity. However, the degree of water-stable aggregates increased significantly when using O horizon as the soil improvement agent among the types of in-situ soil. In contrast, all items related to the chemical properties showed significant differences following the treatment by soil improvement agents. The survival rate according to the treatment of soil improvement agents for the growth and development of Pinus densiflora was higher in the order of organic horizon = no treatment > compound fertilizer > organic fertilizer + compound fertilizer > organic fertilizer; this result was statistically significant with a marginal significance value of the log-rank test(p < 0.05).

A Convergence Study on the Oral Myofunction and Oral Bacteria in the Elderly with Systemic Disease (전신질환 노인의 구강근기능과 구강 세균에 관한 융복합 연구)

  • Kim, Seol-Hee
    • Journal of Digital Convergence
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    • v.19 no.2
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    • pp.315-322
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    • 2021
  • The purpose of this study was to examine the correlations of oral myofunction and oral environment for the elderly with systemic diseases and to suggest need to improve oral health for the elderly. Data were collected from 64 elderly over the age of 65, from April to June 2019. Data were surveyed on general characteristics, oral myofunction, oral health-related quality of life, oral bacteria. Analysis was performed using PASW Statistics ver 18.0. The subjects were 43.8% systemic diseases, among them 40.6 percent of the people with more than two. The number of functional teeth was 18.6. Age was negatively correlated with functional teeth(r=-.384, p<.01) and tongue pressure (r=-).104, p<.001). Tongue pressure was a positive correlation with lip force(r=.279, p<.05). Age and total number of bacteria was negative correlation(r=-.336, p<.01). The functional teeth and total number of bacteria was positive correlation(r=.551, p<.001). The number of systemic diseases and total number of bacteria was positive correlation(r=.327, p<.01) the analysis of oral myofunction and oral bacteria in older patients with systemic diseases It was meaningful in suggesting a plan to improve oral health for the elderly. A practical policy plan was required to improve the quality of oral health life in a super-aged society.

A Study of Prestige Fashion Brands' Visual Identities on Visual Semiotic Analysis of Cosmetic Products' Packaging -Focused on Yves Saint Laurent and Giorgio Armani- (화장품 패키지의 시각기호학적 분석을 통한 패션 명품 브랜드의 시각적 정체성 연구 - 입생로랑과 조르지오 아르마니의 사례를 중심으로 -)

  • Lee, Mi-jin;Jeon, Hyeong-yeon
    • Journal of Communication Design
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    • v.64
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    • pp.64-75
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    • 2018
  • Luxury fashion brands, which have dominated the market of high-priced apparel, bags and shoes, are recently showing changes of stepping into the cosmetics market. The purpose of this study is to examine how luxury fashion brand identity is transferred to cosmetic brand while expanding into luxury cosmetic brand, and to analyze the plastic signs of cosmetic package design and to analyze visual identity through a semi-symbolic system. Therefore, in this study, we tried to analyze the visual semiotic analysis of the package design such as the cushion compact, the lip tint and the brand logo which appeared in the popular product line of the fashion luxury brand such as Yves Saint Laurent and Armani. As a result of the analysis, this study has identified the semantic qualities expressed by each plastic element through the visual semiotic analysis process of the cosmetic package of Yves Saint Laurent and Giorgio Armani. These traits were found to be used as visual signs to reveal the 'Classicism' identity pursued by Yves Saint Laurent and the 'Baroque' identity pursued by Armani. Based on the results of this study, this study finds that the brand identity as a fashion brand is not transferring to the visual identity of cosmetic brands in the case of Yves Saint Laurent. On the other hand, this study found that Armani uses visual communication strategies to effectively transfer the brand identity as a fashion brand to the visual identity of cosmetic brands. On these two different results, it is necessary to examine whether luxury fashion brands and also Korean fashion brands are expanding into the cosmetics market and how they can better grasp the existing brand identity and apply it to the communication strategies of cosmetics brands.

Rehabilitation of posterior support and vertical dimension in a class 3 malocclusion patient: A case report (III급 부정교합 환자에서 상악 가철성 국소 의치와 하악 임플란트 지지 고정성 보철물을 이용한 구강 회복 증례)

  • Oh, Ji-Hwan;Pyo, Se-Wook;Chang, Jae-Seung;Kim, Sunjai
    • The Journal of Korean Academy of Prosthodontics
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    • v.60 no.2
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    • pp.175-186
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    • 2022
  • A crossed occlusion resulting from the presence of posterior teeth in one arch but no opposing teeth in the opposite arch results in collapse of the vertical dimension. In this case, the patient has a class III malocclusion with crossed occlusion and anterior crossbite. In order to evaluate the proper vertical dimension, provisional denture was used to stabilize the vertical occlusal dimension for 3 months. After, provisional fixed restoration was used for the stabilizing occlusal relationship and aesthetic improvement for lip support. Definitive prosthesis in implants in the mandible and abutments in the maxillary were using Porcelain-fused-to-metal crown (PFM) crown and the maxillary unilateral edentulous area was treated with removable partial dentures. Through this, proper support of the posterior region and normal anterior occlusal relationship were formed, and the patient was able to obtain aesthetically and functionally satisfactory treatment results.

Development and Validation of Digital Twin for Analysis of Plant Factory Airflow (식물공장 기류해석을 위한 디지털트윈 개발 및 실증)

  • Jeong, Jin-Lip;Won, Bo-Young;Yoo, Ho-Dong;Kim, Tag Gon;Kang, Dae-Hyun;Hong, Kyung-Jin
    • Journal of the Korea Society for Simulation
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    • v.31 no.1
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    • pp.29-41
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    • 2022
  • As one of the alternatives to solve the problem of unstable food supply and demand imbalance caused by abnormal climate change, the need for plant factories is increasing. Airflow in plant factory is recognized as one of important factor of plant which influence transpiration and heat transfer. On the other hand, Digital Twin (DT) is getting attention as a means of providing various services that are impossible only with the real system by replicating the real system in the virtual world. This study aimed to develop a digital twin model for airflow prediction that can predict airflow in various situations by applying the concept of digital twin to a plant factory in operation. To this end, first, the mathematical formalism of the digital twin model for airflow analysis in plant factories is presented, and based on this, the information necessary for airflow prediction modeling of a plant factory in operation is specified. Then, the shape of the plant factory is implemented in CAD and the DT model is developed by combining the computational fluid dynamics (CFD) components for airflow behavior analysis. Finally, the DT model for high-accuracy airflow prediction is completed through the validation of the model and the machine learning-based calibration process by comparing the simulation analysis result of the DT model with the actual airflow value collected from the plant factory.

Addition of 2 mg dexamethasone to improve the anesthetic efficacy of 2% lidocaine with 1:80,000 epinephrine administered for inferior alveolar nerve block to patients with symptomatic irreversible pulpitis in the mandibular molars: a randomized double-blind clinical trial

  • Aggarwal, Vivek;Ahmad, Tanveer;Singla, Mamta;Gupta, Alpa;Saatchi, Masoud;Hasija, Mukesh;Meena, Babita;Kumar, Umesh
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.22 no.4
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    • pp.305-314
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    • 2022
  • Introduction: This clinical trial aimed to evaluate the anesthetic effect of the addition of 2 mg (4 mg/ml) of dexamethasone to 2% lidocaine (plain or with 1:80,000 epinephrine). The solutions were injected for a primary inferior alveolar nerve block (IANB) to provide mandibular anesthesia for the endodontic treatment of mandibular molars with symptomatic irreversible pulpitis. Methods: In a double-blinded setup, 124 patients randomly received either of the following injections: 2% lidocaine with 1:80,000 epinephrine, 2% lidocaine with 1:80,000 epinephrine mixed with 2 mg dexamethasone, or plain 2% lidocaine mixed with 2 mg dexamethasone, which were injected as a primary IANB. Ten minutes after injection, patients with profound lip numbness underwent electric and thermal pulp sensibility tests. Patients who responded positively to the tests were categorized as "failed" anesthesia and received supplemental anesthesia. The remaining patients underwent endodontic treatment using a rubber dam. Anesthetic success was defined as "no pain or faint/weak/mild pain" during endodontic access preparation and instrumentation (HP visual analog scale score < 55 mm). The effect of the anesthetic solutions on the maximum change in heart rate was also evaluated. The Pearson chi-square test at 5% and 1% significance was used to analyze anesthetic success rates. Results: The 2% lidocaine with 1:80,000 epinephrine, 2% lidocaine with 1:80,000 epinephrine mixed with 2 mg dexamethasone, and plain 2% lidocaine mixed with 2 mg dexamethasone groups had anesthetic success rates of 34%, 59%, and 29%, respectively. The addition of dexamethasone resulted in significantly better results (P < 0.001, 𝛘2 = 9.07, df = 2). Conclusions: The addition of dexamethasone to 2% lidocaine with epinephrine, administered as an IANB, can improve the anesthetic success rates during the endodontic management of symptomatic mandibular molars with irreversible pulpitis.

Fit Tests for Second-class Half Masks (2급 방진마스크 밀착도 평가)

  • Cho, Kee Hong;Kim, Hyun Soo;Choi, Ah Rum;Chun, Ji Young;Kang, Tae Won;Kim, Min Su;Park, Kyeong Hak;Kim, Ze One
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.32 no.2
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    • pp.146-152
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    • 2022
  • Objectives: The purpose of this study is to confirm whether there is a factor to affect the evaluation of fit test of a 2nd class half masks using a OPC test method. Methods: Total 34 adults including Males and Females were tested using OPC-based fit testing equipment while wearing a 2nd class half filtered mask. Results: 1. The result of measuring face dimensions using different tools such as a 3D scanner and digital calipers revealed that the variation of lip width was not statistically significant because there was only a difference of about 4 mm. However, it showed that a difference in face length was statistically significant enough with 10 mm(p<0.000). 2. The fit factor for each exercise stage according to gender was the highest at 124.54(p<0.001) in Step 3, and the fit factor was the lowest at 73.75 in Step 1. 3. In the evaluation of the degree of fit factor according to gender, female passed 67.44%, which was higher than the value in male(p<0.038). 4. The acceptance rate of the group having a face length of shorter than 110 mm was 91.67%. On the other hand, the acceptance rate of the group with a face length of longer than 110 mm was 47.27%(p<0.000). 5. The fit test was possible because the fit factor with 2nd class half masks corresponding to FFP1(Filtering Face Piece 1) was passed 55% or more. Conclusions: The test results showed that using a 2nd class half filtered mask, it is important to wear a properly designed mask so that face size does not affect the fit factor.

Implant-assisted removable partial denture using Milled-Bar and Attachment in partially edentulous maxilla: A case report (상악 부분 무치악 환자에서 Milled-bar와 어태치먼트를 이용한 임플란트 부분 피개의치 수복 증례 보고)

  • Jeong, Yun-Su;Jeong, Chang-Mo;Yun, Mi-Jung;Lee, So-Hyoun;Huh, Jung-Bo
    • The Journal of Korean Academy of Prosthodontics
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    • v.60 no.4
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    • pp.412-419
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    • 2022
  • For treatment of partially edentulous patients, a treatment using implant is widely used. Treatment method using implant are implant fixed prostheses and removable partial dentures, and for patients with severe bone resorption, removable implant overdenture with the effects of aesthetic and reducing cost can be used as treatment options. Specially, prosthesis with milled-bar and attachment has the effect of being splinted between implant fixtures, higher retention and stability than conventional removable partial denture. And it has the effect of improvement of aesthetic through lip support by denture base. In this case, the patient with severe alveolar bone resorption and partial edentulous maxilla and mandible was treated by implant-assisted removable partial denture using Milled-bar and ADD-TOC attachment. The esthetic was improved by removing the clasp because of effects of additional retention by using the attachment, and reducing palatal coverage of implant-assisted removable partial denture. The clinical results were satisfactory on the aspect of aesthetic and masticatory function.

Risk Analysis of All Types of Cancer among Firefighters and Police Officers Using National Health Insurance Claim Data (건강보험 청구 자료를 이용한 소방 및 경찰공무원의 암 종별 위험도 분석)

  • Lee, Woo-Ri;Yun, Byungyoon;Yoo, Ki-Bong;Yoon, Jin-Ha
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.32 no.3
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    • pp.242-252
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    • 2022
  • Objectives: Firefighters and police officers are exposed to various occupational hazards. No studies in Korea have investigated the occurrence of cancer by type of cancer for the two occupations. This study aims to investigate the risk of occurrences associated with types of cancers in firefighters and police officers. Methods: Utilizing National Health Insurance(NHI) Claims data from 2006-2015, the study included 8,871,468 general workers, 25,001 firefighters, and 102,274 police officers. Using general workers as a control group, we calculated the standardized incidence ratios(SIR) by types of cancer for firefighters and police officers. After calculating the SIR for all subjects, the SIR was calculated by stratifying according to gender. Results: SIR of colon cancer 1.38(95% CI, 1.11-1.69), cancer of the liver and intrahepatic bile ducts 1.27(95% CI, 1.04-1.54), and 1.88(95% CI, 1.28-2.65) bladder cancer were higher firefighters than general workers. SIR of Lip, oral cavity, and pharynx 1.26(95% CI, 1.07-1.47), Stomach 1.14(95% CI, 1.06-1.23), colon 1.33(95% CI, 1.21-1.46), liver and intrahepatic bile ducts 1.21(95% CI, 1.10-1.32), pancreas 1.24(95% CI, 1.02-1.49), other skin 1.60(95% CI, 1.26-2.00), bladder 1.27(95% CI, 1.04-1.54), other urinary tract 1.46(95% CI, 1.27-1.68), other parts of central nervous system 1.68(95% CI, 1.10-2.46) were higher police officers than general workers. Conclusions: Both firefighters and police officers are exposed to various cancer occurrence risks, necessitating the development of occupational medical protection measures to reduce risk exposure factors.